Clinical trials: Fracture of Lower Limb
Femoral Neck Fractures, Intertrochanteric Fractures
Opioid-Free Pain Treatment in Trauma Patients
Analgesic drug study that will compare pain outcomes of opioid analgesia and opioid-free analgesia in post-operative orthopedic patients.
- Conditions
- Femoral Neck Fractures, Intertrochanteric Fractures, Femoral Shaft Fracture, Distal Femur Fracture
- Trial name
- NCT06078371
- Testing
- Opioid-free pain treatment
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Kansas Medical Center
Femoral Neck Fractures
Recovery of Physical Functioning After Hip Fracture
The survivors after hip fracture often report severe pain and loss of physical functioning. The poor outcomes cause negative impact on the person's physical functioning and quality of life and put a financial burden on society.
- Trial name
- HIPFRAC (NCT02780076)
- Testing
- Functional training program
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Vestre Viken Hospital Trust
Unstable Trochanteric Fractures
Proximal Femoral Nail Antirotation™ (PFNA) Versus Gamma Nail 3™ (Gamma3) for Intramedullary Nailing of Unstable Trochanteric Fractures
The purpose of this study is to compare rates of any fracture fixation complication and revision rates after intramedullary fixation of unstable trochanteric fractures between the Proximal Femoral Nail Antirotation™…
- Trial name
- PROGAINT-ES (NCT00736684)
- Testing
- Proximal Femoral Nail AntirotationTM (PFNA), Gamma Nail 3TM (Gamma3)
- Where
- 6 sites in Spain
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Femoral Shaft Fractures and Patellar Fractures, Knee Fractures
Development and Clinical Evaluation of a Novel Hollow Cusp Fracture Reducer for Femoral Shaft and Patellar Fractures
This study aimed to develop and clinically evaluate a novel hollow cusp fracture reducer for enhancing the precision and efficiency of closed reduction and internal fixation in patients with femoral shaft fractures and patellar…
- Conditions
- Femoral Shaft Fractures and Patellar Fractures, Knee Fractures, Femoral Fractures
- Trial name
- NCT07534904
- Where
- China
- Volunteers
- 142 people
- Sponsor
- Hanzhong Central Hospital
Ankle Fractures
AORIF Complex Ankle Fractures
The aim of this study is to evaluate the intraarticular lesions, to identify fractures specifically at risk for these, and to assess the results following arthroscopically assisted open reduction and internal fixation of complex…
- Trial name
- NCT04033848
- Testing
- Arthroscopic assisted ankle fracture treatment
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Femoral Neck Fracture
Trochanteric Bursa Repair and Lateral Hip Pain After Hemiarthroplasty for Femoral Neck Fracture
This study aims to determine whether repairing the trochanteric bursa during hip hemiarthroplasty reduces lateral hip pain after surgery in patients aged 65 years and older with femoral neck fractures.
- Trial name
- NCT07878143
- Testing
- Trochanteric Bursa Repair, Trochanteric Bursa Left Unrepaired
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Osman Sarıyar
Neck of Femur Fracture
Comparative Effects of Closed Kinetic Chain Exercises and Mobilization Exercises in Elderly Females With NFF
This study investigates the additional benefits of Mobilization Exercises and Closed Kinetic Chain Exercises (CKCE) in elderly individuals with post-operative neck of femur fracture.
- Trial name
- NCT06901843
- Testing
- Mobilizations Exercises, Closed Kinetic Chain Exercises
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Superior University
Fast-track Protocol, Hip Fracture
IMPLICATION OF FAST-TRACK PROTOCOL FOR HIP FRACTURE FIXATION IN ALEXANDRIA UNIVERSITY HOSPITALS
The present study aims to evaluate the impact of fast-track protocol of hip fracture fixation within 48 hours on patients' mortality and morbidities.
- Conditions
- Fast-track Protocol, Hip Fracture, 30 Days Mortality
- Trial name
- NCT06881121
- Testing
- Fast-track protocol for hip fracture fixation
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Alexandria University
Ankle Injuries, Fracture, Ankle
Patient Education Using 3D Printed Model
Complex high energy fractures of the lower extremity are life changing injuries and are known to be associated with poor functional outcome post operatively.
- Trial name
- NCT04009252
- Testing
- 3D Model Education
- Volunteers
- 28 people
- Sponsor
- Ottawa Hospital Research Institute
Hip Fractures, Post Operative Pain
Dose and Concentration Relationship for PENG Block in Hip Surgery
A number of peripheral nerve blocks are routinely performed in patients who will undergo orthopedic hip surgery for pain relief.
- Trial name
- NCT05400148
- Testing
- Bupivacaine Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Ankle Fractures
Local Multimodal Injection Versus Regional Anesthesia in Controlling Pain for Treating Rotational Ankle Fractures
The investigators plan to evaluate the efficacy in reducing post-operative pain between local multimodal analgesia as compared to regional anesthesia in rotational ankle fractures.
- Trial name
- NCT05019638
- Testing
- Regional anesthesia group, Local multimodal analgesia group
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Hip Fractures
Goal Directed Hemodynamic Therapy Based on Noninvasive Monitoring in Patients With Hip Fracture
Crude incidence rate in Spain of hip fracture in people over 65 years was 511 cases per 100,000 in 2002. About 30% of patients die in the first year.
- Trial name
- NCT02479321
- Testing
- GDT based on noninvasive monitoring, System ClearSight® and Platform EV Clinic 1000®
- Where
- Spain
- Volunteers
- 568 people
- Sponsor
- Juan-Víctor Lorente, MD, PhD
Ankle Fractures, Leg Fracture
Sciatic Nerve Block for Ankle and Leg Fracture Manipulation in the Emergency Department
The goal of this feasibility clinical trial is to assess the acceptability of ultrasound-guided sciatic nerve block when performed at Emergency Departments for manipulation and temporary stabilization of distal leg and ankle…
- Trial name
- AnkleMan (NCT06329752)
- Testing
- Ultrasound-guided Sciatic Nerve block (20 mL of 2% Lidocaine)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Osteoporosis
Clinical Validation of BBCT-hip
The clinical study is aimed at assessing the accuracy of the in silico methodology BBCT-hip. BBCT-hip takes as inputs the subject-specific height and weight, and the CT scan of his femur to predict the risk of fracture for the…
- Trial name
- ValidaBBCT-hip (NCT06270758)
- Testing
- CT scan at the femur
- Where
- 2 sites in Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Anesthesia, Hip Fractures
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
The ANDES Platform Trial is a pragmatic, multicenter, adaptive randomized controlled platform trial in patients aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Anesthesia, Hip Fractures, Dementia, Cognitive Impairment
- Trial name
- ANDES platform (NCT06452147)
- Testing
- Nerve block, Standard anesthesia care, Bupivacaine liposome
- Where
- 13 sites in China
- Volunteers
- 1,860 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Total Knee Arthroplasty, Total Hip Arthroplasty (THA)
AI-based Rehabilitation for Hip and Knee Surgery Patients
This study aims to evaluate the efficacy and safety of an AI-based home rehabilitation application ("Exersite Rehab") for patients who have undergone hip or knee arthroplasty(Total Knee Arthroplasty (TKA), Total Hip Arthroplasty…
- Conditions
- Total Knee Arthroplasty, Total Hip Arthroplasty (THA), Hip Fracture Surgery
- Trial name
- NCT07505628
- Testing
- Exersite Rehab (AI-based Mobile Application), Printed Educational Brochure (Traditional Rehabilitation)
- Where
- 2 sites in South Korea
- Volunteers
- 106 people
- Sponsor
- Gangnam Severance Hospital
Patella Fracture
Comparison of Patella Plating Versus Tension Band Wiring for the Treatment of Unstable Patellar Fractures
This study aims to compare the efficacy and safety of patella anatomical locking plate fixation versus tension band wiring in the treatment of patellar fractures.
- Trial name
- WASP (NCT06981039)
- Testing
- Patella Anatomical Locking Plate, Tension Band Wiring
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Fractured Neck of Femur
Optimal Positioning of Local Anaesthetic in Femoral Nerve Block Prior to Hip Surgery
The aim of the study is to compare patient comfort and analgesic efficacy of ultrasound guided femoral nerve block using the following endpoints: circumferential spread, anterior or posterior local anaesthetic deposition prior to…
- Trial name
- NCT01527812
- Testing
- Femoral nerve block
- Where
- Ireland
- Volunteers
- 60 people
- Sponsor
- Cork University Hospital
Broken Leg
Tibial Shaft Nailing Treated With Suprapatellar Nailing
The goal of this project is to determine the incidence of intra-articular knee pathology following tibial shaft fractures as evaluated by intraoperative knee aspiration and physical exam, and to evaluate for chondral injuries…
- Trial name
- NCT02510339
- Testing
- Observation
- Volunteers
- 16 people
- Sponsor
- Orlando Health, Inc.
Ankle Fractures, Foot Fracture
Waterproof Casting Versus Standard Casting for Short Leg Walking Casts
The purpose of the study is to determine whether the use of waterproof padding in short leg walking casts will lead to an increase in cast-related complications, as compared to the standard non-waterproof casting in children.
- Conditions
- Ankle Fractures, Foot Fracture, Ankle Sprains, Foot Sprain
- Trial name
- NCT04961957
- Testing
- Waterproof padding, Non-waterproof padding
- Where
- United States
- Sponsor
- West Virginia University
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