Clinical trials: Fracture of Lower Limb
Ankle Fractures
Combined Randomised and Observational Study of Type B Ankle Fracture Treatment
This study will determine whether operative management confers improved short and long-term outcomes for patients with isolated AO type 44-B1 distal fibula fractures when compared with non-operative management.
- Trial name
- CROSSBAT (NCT01134094)
- Testing
- Open reduction internal fixation of the ankle, Non Operative
- Where
- 21 sites in Australia
- Volunteers
- 160 people
- Sponsor
- The University of New South Wales
Ankle Fracture, Malleolus Fracture
Surgical Versus Nonsurgical Treatment of Fibular Fractures: A Prospective Randomized Study
Isolated surgical repair of the inside portion of the tibia may be enough to stabilize an ankle fracture in which both the tibia and the fibula are broken.
- Conditions
- Ankle Fracture, Malleolus Fracture, Medial Malleolus Fracture, Bimalleolar Fracture
- Trial name
- NCT02032966
- Testing
- Nonsurgical, Surgical
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Tennessee
Hip Fractures
Improvement of Function After Hip Fracture in Geriatric Rehabilitation Unit Via Augmented Reality Device "SELFIT"
Type of study: prospective interventional the purposes of the research :To examine the effect of treatment using the SELFIT system on function, walking and balance in patients after hip fractures hospitalized in the geriatric…
- Trial name
- NCT06029361
- Testing
- Selfit Device group, Control Group
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Femoral Neck Fractures
Comparison of Clinical Efficacy Between Dynamic Dip Screw and Cannulated Compression Screw for Fresh Femoral Neck Fracture
For fresh femoral neck fracture internal fixation, both DHS and CCS can make strong fixation of hip and have good recovery. There is no statistical difference in complications after surgery between the two procedures.
- Trial name
- NCT04959370
- Testing
- internal fixation implantation of dynamic hip screw, internal fixation implantation of cannulated compression screw
- Where
- China
- Volunteers
- 91 people
- Sponsor
- Peking University Third Hospital
Ankle Fractures
Hardware Removal After ORIF of Ankle Fractures
Ankle fractures account for 10 % of fractures in the adult population. A part of patients (40%) is treated surgically. After healing of the fractures, about one year after the operation, a surgery is often performed to remove the…
- Trial name
- NCT05798741
- Testing
- Hardware removal
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Hôpital Fribourgeois
Ankle Injuries, Fracture
Lymphomyosot for Ankle Edema Following Fracture
Ankle fractures are invariably complicated by severe soft-tissue swelling which can significantly prevent surgical repair (open reduction and internal fixation - ORIF) of the fractured bone for up to two weeks.
- Trial name
- NCT00884988
- Testing
- Lymphomyosot
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Shaare Zedek Medical Center
Hip Fractures, Femoral Shaft Fractures
Trial of a Distal Targeting System for Cephalomedullary Nails as Part of Surgical Repair of Hip and Femoral Shaft Fractures
This study will be a prospective, case - control trial looking at the use of a previously FDA approved device made by Stryker, a distal targeting system that eases the distal targeting of screws in cephalomedullary nails in hip…
- Trial name
- NCT03943329
- Testing
- Standard of Care, Distal targeting device technique of distal screw placement
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Pain, Postoperative, Ankle Fractures
Efficacy of Multimodal Periarticular Injections in Operatively Treated Ankle Fractures
The purpose of this study is to determine the efficacy and safety of a peri-articular multimodal injection for post-operative pain control following operative management of closed, rotational ankle fractures.
- Trial name
- NCT02967172
- Testing
- Ropivacaine, Epinephrine, Morphine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Iowa
Pelvis; Fracture
Surgical Treatment of Pelvis in Fragility Fracture in Germany: a Prospective, National, Multicenter, Observational, Comparative Cohort Study Comparing Isolated Posterior Versus Combined Anterior-posterior Surgical Fracture Stabilization
Over a period of approximately two years, patients above the age of 65 who have suffered from an FFP equal to or higher than type IIc FFP, according to Rommens and Hofmann, will be eligible for inclusion.
- Trial name
- AO TOP (NCT06550934)
- Testing
- Fracture stabilization
- Volunteers
- 420 people
- Sponsor
- AO Innovation Translation Center
Delirium in Old Age, Frailty
Association of Frailty and Delirium in Elderly Hip Fracture Patients
Several studies have shown that frailty can be used as a marker for risk of adverse outcomes in elderly patients such as falls, disability, hospitalization, mortality, and can be used to predict patient clinical outcomes.
- Trial name
- NCT05246254
- Testing
- Frailty index scale
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Trimalleolar Fracture, Posterior Malleolus
Fixation of the Posterior Malleolus in Medium-sized Trimalleolar AO Weber-B Fractures.
The optimal treatment of ankle fractures with involvement of the posterior malleolus remains a subject of debate. Despite a large amount of literature on the role of the posterior malleolus in a so-called trimalleolar fracture…
- Conditions
- Trimalleolar Fracture, Posterior Malleolus, Open Reduction and Internal Fixation
- Trial name
- POSTFIX (NCT02596529)
- Testing
- Fixation, NO Fixation
- Where
- 3 sites in Netherlands
- Volunteers
- 84 people
- Sponsor
- Medical Center Haaglanden
Ankle Fracture, Ankle Sprain
Applicability of the Ottawa Ankle Rules
The aim of this prospective study was to compare outcomes in patients handled by emergency physician according to OAR versus by an orthopedic resident.
- Trial name
- NCT01561365
- Testing
- Ottawa ankle rules
- Where
- Israel
- Volunteers
- 92 people
- Sponsor
- Hadassah Medical Organization
Hip Fracture, Antithrombotic Therapy
Assessing the Effectiveness and Safety of Pericapsular Nerve Group (PENG) Block in Hip Fracture Patients on Antithrombotic Therapy
PENG block will be done on patients with hip fracture either receiving antithrombotic therapy or not under ultrasound guidance
- Conditions
- Hip Fracture, Antithrombotic Therapy, PENG Block
- Trial name
- PENG Block (NCT06582667)
- Testing
- PENG block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Hip Arthroplasty, Postoperative Pain
Comparison of Pericapsular Nerve Group+ Lateral Femoral Cutaneous Nerve Block Versus Lumbar Erector Spinae Plane Block in Hip Arthroplasty Surgery
Hip replacement surgery (partial or total hip arthroplasty) is commonly performed in elderly patients and is associated with significant postoperative pain.
- Conditions
- Hip Arthroplasty, Postoperative Pain, Hip Fractures, Postoperative Delirium (POD)
- Trial name
- NCT07445009
- Testing
- PENG + LFCN Block, PENG + Lumbar ESP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Automobile Driving With an Aircast Walker, Automobile Driving With a Walking Cast
Effects of Right Lower Limb Orthopedic Immobilization on Braking Function
Research on the implications of orthopedic injury and surgery on automobile driving ability has been limited. Only a handful of orthopedic issues have been studied to date, especially the safe postoperative resumption of driving.
- Trial name
- NCT01171287
- Testing
- Driving with an Aircast Walker, Driving with a walking cast, Driving with a running shoe
- Where
- 2 sites in Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Hip Fractures
Comparison of Cryoablation of Pericapsular Nerve Group (PENG) to Fascia Iliaca Catheter in Patients With a Hip Fracture
The purpose of this study is to determine if patients with hip fractures who undergo cryoablation of the PENG have improved pain control 30 days from surgery when compared to those who have a fascia iliaca catheter.
- Trial name
- NCT06278987
- Testing
- PENG block and cryoablation, fascia iliaca compartment block
- Sponsor
- University of Minnesota
Hip Fracture, Aged
A New Clinical Pathway for Patients With Fractured Neck of Femur
The intention is to evaluate the effectiveness of a multi-factorial medical treatment of patients with hip fractures in a specially designed unit for elderly hip fracture patients (orthogeriatric unit) as compared to traditional…
- Trial name
- NCT00667914
- Testing
- geriatric work-up, Orthopedic care as usual
- Volunteers
- 397 people
- Sponsor
- Norwegian University of Science and Technology
Femoral Neck Fractures, Bone Density
Radiostereometric Analysis of Acetabular Wear and Periprosthetic Bone Mineral Density Changes in Hemiarthroplasties
Substudy and continuation of HEMI-SAB-UUS (NCT00491673) Study on radiostereometric measurements of acetabular wear in bipolar hemiarthroplasties and measurements of periprosthetic bone mineral density in cemented and uncemented…
- Conditions
- Femoral Neck Fractures, Bone Density, Acetabular Wear, Hemiarthroplasty
- Trial name
- HEMI-RSADEXA (NCT00607516)
- Testing
- Cemented primary bipolar hemiarthroplasty of the hip, Uncemented primary bipolar hemiarthroplasty of the hip
- Where
- Norway
- Volunteers
- 22 people
- Sponsor
- Ullevaal University Hospital
Hip Fracture, Analgesia Post Fracture
PENG Block: Continuous Infusion vs. Programmed Intermittent Bolus in Neck of Femur Fracture
Pericapsular Nerve Group Block (PENG) is an effective regional anaesthesia modality in providing analgesia following neck of femur fracture.
- Trial name
- NCT07046052
- Testing
- continuous infusion of levobupivacaine, Programmed Intermittent Bolus of Levobupivacaine
- Where
- Ireland
- Volunteers
- 150 people
- Sponsor
- University College Cork
Ankle Fracture - Medial Malleolus
Medial Malleolus: Operative Or Non-operative
Medial malleolus: Operative Or Non-operative (MOON study) Ankle fractures are a common Orthopaedic trauma presentation, accounting for approximately 10% of the workload.
- Trial name
- MOON (NCT03362229)
- Testing
- Fixation, Non-fixation
- Where
- United Kingdom
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Royal Infirmary of Edinburgh
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