Clinical trials: Fracture of Lower Limb
Venous Thromboembolism
Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Thromboembolism in Patients Undergoing Hip Fracture Surgery
The primary objective was to compare the efficacy of once daily [q.d] subcutaneous [s.c.] injections of Semuloparin sodium (AVE5026) with q.d. s.c.
- Trial name
- SAVE-HIP2 (NCT00721760)
- Testing
- Enoxaparin sodium, Semuloparin sodium
- Where
- 25 sites in United States, Argentina and 23 more
- Volunteers
- 1,003 people
- Sponsor
- Sanofi
Hip Fractures, Surgical Blood Loss
Tranexamic Acid in Intertrochanteric and Subtrochanteric Femur Fractures
The objective of this study is to evaluate the effect of Tranexamic Acid (TXA) on blood loss and need for perioperative blood transfusion following intertrochanteric and subtrochanteric femur fractures.
- Trial name
- NCT02580227
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Good Samaritan Regional Medical Center, Oregon
Hip Fractures
Comparison of Pericapsular Nerve Group Block With Suprainguinal Fascia Compartment Block in Hip Fractures
Ultrasound-guided Supra-inguinal Fascia Iliaca compartment Block (SIFCB) and Pericapsular Nerve Group Block (PENG) are increasingly being used for postoperative analgesia for hip surgery.
- Trial name
- NCT06169462
- Testing
- PENG block, PENG block+ SIFCB
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Fracture; Radius, Lower or Distal End
Anterior Plate Osteosynthesis of Fractures of the Lower Extremity of the Radius: Does the Systematic Use of Short Epiphysic Screws Limit the Posterior Protrusion of the Screws Without Compromising Stability
Anterior plate osteosynthesis of fractures of the lower extremity of the radius may be accompanied by tendinous complications : tenosynovitis of extensors or even tendon ruptures caused by the end of the epiphyseai screws.
- Trial name
- SHORT (NCT04094935)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Femoral Fractures
European Quality of Care Pathways Study on Proximal Femur Fracture (EQCP-PFF)
Care pathways, a complex intervention to (re)organise, standardize and evaluate care processes, are used worldwide and in different kinds of settings. Although their international use, the impact is unclear.
- Trial name
- EQCP-PFF (NCT00962910)
- Testing
- PFF evidence based pathway
- Volunteers
- 514 people
- Sponsor
- European Pathway Association
Coronary Heart Disease, Stroke
Examining the Long-Term Risks of Oophorectomy
At the time of hysterectomy for benign disease, the overall health benefits of preserving ovarian function in a large population of women have not been established.
- Conditions
- Coronary Heart Disease, Stroke, Breast Cancer, Ovarian Cancer
- Trial name
- NCT00655447
- Where
- United States
- Volunteers
- 32,175 people, healthy volunteers welcome
- Sponsor
- Parker, William H., M.D.
Fracture of Femoral Neck
Clinical Study of a Novel Sliding Compression Locking Plate in the Treatment of Fresh Femoral Neck Fractures
To verify the safety and efficacy of sliding compression locking plates in the treatment of fresh femoral neck fractures
- Trial name
- NCT06713291
- Testing
- Sliding compression locking plate, Three cannulated compression screws
- Where
- 3 sites in China
- Volunteers
- 1,150 people
- Sponsor
- Chinese PLA General Hospital
Hip Fractures
Surgical Treatment of Hip Fractures Under Peripheral Regional Anesthesia
The study investigates whether treatment of proximal femoral fractures is possible using a peripheral regional anesthesia technique.
- Trial name
- NCT04005404
- Testing
- Ropivacaine (sciatic nerve block), Ropivacaine (lumbar plexus block L2-L4), Ropivacaine (lumbar plexus block Th12-L1)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Helios Research Center
Tibial Fracture
Autologous Implantation of Mesenchymal Stem Cells for the Treatment of Distal Tibial Fractures
Mesenchymal stem cells are found in bone marrow, and have the ability to differentiate into different tissue types. The primary objective of the study is to examine the safety of using such cells to treat patients suffering from…
- Trial name
- NCT00250302
- Testing
- autologous mesenchymal stem cells implantation
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Hadassah Medical Organization
Femur Fracture
Post-operative Anemia in Lateral Fractures of the Femur.
It was conducted a prospective study with a series of 45 patients with lateral fragility fractures of the femur treated by three different intramedullary nails.
- Trial name
- NCT05225753
- Testing
- hemoglobin serum value
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Femoral Neck Fractures
Intraoperative Monitoring of Femoral Head Perfusion
An ICP monitor will be used to record blood flow/perfusion of the femoral head following fixation of femoral neck fractures. FDA approved device but not for this use.
- Trial name
- NCT04110639
- Testing
- Intracranial pressure (ICP) monitor, Standard of Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Healthcare of Atlanta
Leg Injury, Bone Fracture
Electromiographic Analysis of the Quadriceps After Trauma
The lower limb is the region most affected by fractures in the human body. The magnitude of the trauma can cause injuries to structures adjacent to the fracture, promoting joint instability and consequently predisposition to…
- Trial name
- NCT05574556
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Anesthesia Morbidity, Anesthesia; Adverse Effect
Comparison of CLSB With Sedation Versus General Endotracheal Anesthesia on Postoperative Outcomes in Elderly Patients Undergoing Hip Fracture Surgery
Hip fracture is a global public health problem. The postoperative mortality and disability rate of hip fracture is high, and early surgery is still the most effective treatment method, but these patients are often associated with…
- Trial name
- NCT03318133
- Testing
- anesthesia
- Where
- China
- Volunteers
- 1,086 people
- Sponsor
- Shanghai 6th People's Hospital
Fall Injury, Hip Fractures
Fall, Fracture and Frailty
This project aims to improve the global outcome for an aging individual after a traumatic fall, through identifying conditions contributing to a fall and promoting recovery and rehabilitation.
- Conditions
- Fall Injury, Hip Fractures, Risk Reduction, Osteoporosis, Osteopenia
- Trial name
- FFF (NCT05712252)
- Where
- Sweden
- Volunteers
- 1,200 people
- Sponsor
- Region Skane
Hip Fractures, Hip Disease
CLIC1 in Patients Presenting PD
In this study, mononuclear cells, particularly monocytes, were collected from the peripheral blood of elderly patients who underwent orthopedic hip surgery under spinal anesthesia.
- Trial name
- NCT05446181
- Testing
- Perioperative delirium, Hip surgery
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Seoul National University Bundang Hospital
Hip Fractures, Older Patients
Prospective Observational Study Based on a Cohort of Geriatric Patients With Hip Fracture Treated in the Centers Belonging to the GIOG Group
The study aims to collect the clinical activity and management data of the Orthogeriatrics and Orthopedics Units participating in the study on a continuous and long-term basis.
- Conditions
- Hip Fractures, Older Patients, Comprehensive Geriatric Assessment
- Trial name
- GIOG (NCT05150249)
- Where
- 11 sites in Italy
- Volunteers
- 7,000 people
- Sponsor
- University of Milano Bicocca
Tibial Fractures, Surgery
Clinical Validation of the C-Arm Rotational View (CARV) to Avoid Rotational Malalignment After Intramedullary Nailing of Tibial Shaft Fractures.
Tibia shaft fractures are common long bone fractures in the field of Orthopaedic Trauma. In the USA, a total of 492.000 tibial fractures were reported per year by the National Center of Health Statistics (NCHS).
- Conditions
- Tibial Fractures, Surgery, Complication,Postoperative
- Trial name
- NCT05459038
- Testing
- C-Arm Rotational View (CARV)
- Where
- 2 sites in Australia, Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Tibial Fractures, Fracture Infection
Zimmer® Natural Nail® (ZNN) Bactiguard Tibia Post-Market Clinical Follow-up Study
Primary objective of this study is to compare fracture related infection (FRI) rates of ZNN Bactiguard Tibia to conventional uncoated titanium-alloy nails 12 months after tibia fracture fixation.
- Trial name
- NCT05022485
- Testing
- ZNN Bactiguard tibia
- Where
- 16 sites in Austria, France and 6 more
- Volunteers
- 500 people
- Sponsor
- Zimmer Biomet
Tibia Fracture
Unreamed Intramedullary Tibial Nailing in Treatment of Open IIIa Diaphyseal Tibial Fractures in Adults
To study the incidence of non union of Unreamed intramedullary nailing in type IIIa Open diaphyseal fractures of the tibia as a primary outcome and the incidence of complications and clinical and functional outcome as a secondary…
- Trial name
- NCT06280417
- Testing
- Unreamed intramedullary tibial nail
- Volunteers
- 25 people
- Sponsor
- Assiut University
Tibia Fracture
M.I.P.O. vs Intramedullary Nailing in Tibia Fractures
The investigators are comparing two methods of standard treatments in distal tibial fractures. locked plating (M.I.P.O. technique) with intramedullary nailing.
- Trial name
- MINT (NCT01047826)
- Testing
- Minimally Invasive Plate Osteosynthesis, intramedullary tibial Nailing
- Where
- Saudi Arabia
- Volunteers
- 180 people
- Sponsor
- King Abdullah International Medical Research Center
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