Clinical trials: Fracture of Lower Limb
Hip Fractures, Muscular Atrophy
Effects of Exercise on Markers of Inflammation in Skeletal Muscle in Elderly Hip Fracture Patients
Decreased skeletal muscle mass is a prevalent condition among the elderly, and an important cause of disability and functional decline.
- Trial name
- NCT00006194
- Testing
- Exercise
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)
Geriatric Hip Fracture
A Comparative Evaluation of Nottingham Hip Fracture Score (NHFS) and Acute Physiology and Chronic Health Evaluation (APACHE) II Score to Predict 30-day Mortality in Geriatric Patients Above 60 Years Undergoing Hip Fracture Surgery.
This study aims to compare the Nottingham Hip Fracture Score (NHFS) and the Acute Physiology and Chronic Health Evaluation II (APACHE II) score in predicting 30-day mortality in geriatric patients over 60 years old undergoing hip…
- Trial name
- NCT06598566
- Testing
- Nottingham Hip Fracture Score (NHFS) score, Acute Physiology and Chronic Health Evaluation (APACHE)-II score
- Where
- India
- Volunteers
- 182 people
- Sponsor
- Tata Main Hospital
Hip Fractures
Activating Older People After a Hip Fracture
The main aim of this study is to determine if the ActiveHip tele-rehabilitation mobile application improves the functional level and the quality of life of patients who undergone hip surgery after a fracture.
- Trial name
- ActiveHip (NCT04859309)
- Testing
- ActiveHip+ mobile application, Standard care in a hip fracture
- Where
- Spain
- Volunteers
- 104 people
- Sponsor
- Universidad de Granada
Femoral Fractures
A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Distal Femur Fractures
This study looks at two (2) types of surgical treatments and hopes to answer the question, "which is the best way to surgically treat a distal femur fracture?" Both procedures being studied are standard of care (used routinely)…
- Trial name
- NCT00429663
- Testing
- reamed, interlocking intramedullary nail, locking periarticular plate
- Where
- 22 sites in United States
- Volunteers
- 160 people
- Sponsor
- Boston Medical Center
Osteomyelitis, Bone Infection
Clinical Effectiveness of S53P4 Bioactive Glass in Treatment of Long-bone Chronic Osteomyelitis
This clinical trial studies the clinical effectiveness of S53P4 bioactive glass (BAG) as a bacterial growth inhibiting bone graft substitute in a one-stage or two-stage surgical procedure for treatment of chronic long bone…
- Conditions
- Osteomyelitis, Bone Infection, Non-Union Fracture, Bone Infection of Lower Leg
- Trial name
- NCT04945434
- Testing
- S53P4 bioactive glass (BonAlive)
- Volunteers
- 78 people
- Sponsor
- Academisch Ziekenhuis Maastricht
Femoral Fractures, Hip Fractures
A Study to Evaluate the Safety and Effectiveness of TRIGEN™ INTERTAN™ (10S Models)
This is a post-market study to evaluate the revision rate of femoral fractures, treated with INTERTAN 10S Nails at one-year post-operation.
- Trial name
- NCT04865146
- Testing
- TRIGEN™ INTERTAN™
- Where
- 7 sites in China
- Sponsor
- Smith & Nephew Medical (Shanghai) Ltd
Femoral Fractures
Supracondylar Distal Femur Fractures and Abaloparatide
Supracondylar femur fractures in the geriatric population present a unique challenge to the orthopaedic surgeon both in terms of fixation, healing, and final extremity axial alignment.
- Trial name
- NCT04626141
- Testing
- Abaloparatide
- Where
- United States
- Sponsor
- Daniel Horwitz
Hip Infection
Relationship Between Preoperative Subcutaneous Trochanteric Fat Thickness and Postoperative Infection Risk
The effect of preoperative subcutaneous trochanteric fat thickness and trochanteric soft tissue thickness on postoperative infection risk in patients undergoing hemiarthroplasty for femoral neck fracture
- Trial name
- NCT06428760
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara City Hospital Bilkent
Hip Fractures
Patients With Acute Hip Fractures Will Receive Either the PENG Block or no Block Respectively.
Hip fracture pain is often severe and traditionally managed by systemic opioids which have increased risk of side effects in frail elderly patients.
- Trial name
- PENGBlock (NCT04996979)
- Testing
- Ropivacaine 0.5% Injectable Solution
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- Singapore General Hospital
Hip Fracture
Fast Track Admittance of Hip Fracture Patients
The study examines time spent in the emergency room on admission of patients with hip fracture in a cohort with a traditional setup compared with a prospective cohort with a fast track admission schedule including nurse…
- Trial name
- NCT00345488
- Volunteers
- 300 people
- Sponsor
- Hvidovre University Hospital
Hip Fractures
Stroke Volume Optimisation in Patients With Hip Fracture
The aim of this study is to assess whether intra-operative fluid supplementation (to improve tissue perfusion) can reduce the incidence of postoperative complications in elderly patients with hip fracture.
- Trial name
- FRACTALE (NCT00444262)
- Testing
- hemodynamic optimisation guided using esophageal Doppler, VOLUVEN and others solute
- Where
- 19 sites in France
- Volunteers
- 215 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fracture Non Union, Fracture Healing
Prospective Validation Study of the CD8+TEMRA Cells As a Prognostic Biomarker of Healing Outcome After Fracture
In approx. 10-15% of all fracture patients, there is a prolonged healing time or even a complete absence of fracture healing (non-union).
- Conditions
- Fracture Non Union, Fracture Healing, Long Bone Delayed-Union Fracture, Humerus Shaft Fracture
- Trial name
- BioBone (NCT06658379)
- Testing
- CD8+TEMRA
- Where
- 7 sites in Germany
- Volunteers
- 640 people
- Sponsor
- Charite University, Berlin, Germany
Bimalleolar Ankle Fractures
CMF Bone Stimulation as Adjunct to Surgical Treatment of Ankle Fractures
The OL1000 is intended to be used as a non-invasive adjunctive treatment for adult males or females that have sustained a closed, unstable ankle fracture that requires surgical treatment for stabilization.
- Trial name
- NCT02688855
- Testing
- Active Combined Magnetic Field OL1000 Bone Growth Stimulator
- Where
- 9 sites in United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Encore Medical, L.P.
Femoral Neck Fractures
Does Capsulotomy in Closed Reduction of Femoral Neck Fractures Decrease Incidence of Avascular Necrosis?
Femur's neck injuries are frequently encountered fractures. They are usually due to high energy or low energy indirect trauma. Healing of these fractures is usually hindered due to "avascular necrosis (AVN)" or "non-union" of the…
- Trial name
- NCT06436352
- Testing
- Capsulotomy and fixation, Fixation only
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kasr El Aini Hospital
Femoral Fracture
The Role of Fat Emboli in the Trauma Inflammatory Response
This is an observational study designed to investigate the role of fat emboli in patients who are undergoing a tibial or femoral fracture procedure in the operating room.
- Trial name
- NCT02069327
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Poudre Valley Health System
Hip Fracture
Training of Patients With Hip Fracture
The primary purpose of this study is to illustrate whether there is a difference in the 6 minutes walking test in patients with hip fractures who have received 6 vs. 12 weeks of physical training after discharge from hospital.
- Trial name
- NCT01174589
- Testing
- Strength training
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Lolland Community, Denmark
Tibial Fractures
Mobile Monitoring of Fracture Healing
The objective of this study is to develop methods for using forces measured on circular external fixators to predict the state of individual patient's healing of severe tibial fractures and defects.
- Trial name
- NCT02534259
- Testing
- Force monitoring of external fixator struts
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Milton S. Hershey Medical Center
Intertrochanteric Fractures
The Effect of Loss of Offset After Pertrochanteric Fracture Treated With a Intramedullary Nail
The purpose of this study is determine the relationship between pain and protrusion of the implant after surgery for a intertrochanteric fracture.
- Trial name
- PLAIN (NCT01344785)
- Testing
- Intramedullary nailing
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Danderyd Hospital
Hip Fractures
Balance Rehabilitation After Hip Fracture Surgery
The overall functional gain by balance rehabilitation after hip fracture surgery has not yet been fully investigated. Therefore, clinical studies should be conducted to evaluate the effectiveness of systematic and safe balance…
- Trial name
- BRS (NCT03618576)
- Testing
- Balance specific exercise
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Hip Fracture
Strength Training After Hip Fracture Surgery
The purpose of this study is to examine the effect of progressive strength training of the fractured limb in patients with hip fracture, during admittance in an acute orthopedic ward.
- Trial name
- NCT00848913
- Testing
- Rehabilitation with strength training, Rehabilitation without strength training
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Hvidovre University Hospital
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