Clinical trials: Fracture of Lower Limb
Sarcopenia, Hip Fractures
Sarcopenia and Bone Mineral Density Relation in Hip Fracture Patients
The study aims to investigate the relationship between sarcopenia and bone mineral density (BMD) in patients with hip fractures using sonographic thigh adjustment ratio (STAR) and dual-energy X-ray absorptiometry (DXA), as well…
- Trial name
- NCT06508957
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Kastamonu University
Learning Curves and Outcomes of Simulation-based Training
Is Two-on-one Instruction in Virtual Reality Simulation-based Training of Operating Fractures of the Hip for Medical Students as Effective as One-on-one Instruction
The training of orthopedic surgeons has historically relied heavily on an apprenticeship model as the primary way of teaching the various procedures an aspiring surgeon needs to master.
- Trial name
- NCT06612619
- Testing
- Dyad instruction
- Where
- Denmark
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Multiple Closed Pelvic Fractures With Disruption of Pelvic Ring, Fragility Fracture
Early Internal Fixation Versus NonOperative Care With Early Rehabilitation for LC1 Fragility Fractures of the Pelvis
The goal of this randomized pilot study is to assess feasibility of the trial and to collect information to inform the design of a definitive trial.
- Conditions
- Multiple Closed Pelvic Fractures With Disruption of Pelvic Ring, Fragility Fracture, Internal Fixation, Nonoperative Care
- Trial name
- PIVOT-LC1-Pi (NCT06496867)
- Testing
- Early Internal Fixation, Nonoperative Care with Early Rehabilitation
- Where
- 13 sites in United States, Spain
- Volunteers
- 48 people
- Sponsor
- University of Southern California
Lateral Malleolus Fractures
Double Compression Screw Fixation for Symptomatic Non-union of Lateral Malleolar Ankle Fractures
The aim of this prospective clinical trial study is to evaluate the clinical and radiological outcomes of treating non-union of the lateral malleolar ankle fractures by double compression screw fixation technique.
- Trial name
- NCT07539922
- Testing
- Double Compression Screw Fixation for Symptomatic Non-union of Lateral Malleolar Ankle Fractures
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Sohag University
Hip Fractures, Anesthesia
Variations in Anesthesia Care for Hip Fracture Surgery
The investigators will use health administrative data to examine the variation of anesthesia type for hip fracture surgery, as well as sources of variation and predictors of variation.
- Conditions
- Hip Fractures, Anesthesia, Death
- Trial name
- NCT02787031
- Testing
- Neuraxial anesthesia, General anesthesia
- Where
- Canada
- Volunteers
- 107,317 people
- Sponsor
- Ottawa Hospital Research Institute
Hip Fractures, Cognitive Impairment
Optimized Rehabilitation of Older Adults With Hip Fracture and Signs of Cognitive Impairment - Feasibility Study
Older adults suffering from a hip fracture are a significant concern, with higher incidence rates among women. Mortality rates post-hip fracture are alarming, with up to 8-fold increased risk within 3 months and significant…
- Trial name
- ENHANCE (NCT06286722)
- Testing
- Progressive, individualized and structured exercise program
- Where
- 6 sites in Denmark
- Volunteers
- 20 people
- Sponsor
- Lolland Community, Denmark
Tibial Fracture, Femoral Fracture
Magnesium-Titanium Hybrid Intramedullary Nail System For Long Bone Fractures
This is a prospective, multicenter, randomized, controlled, non-inferiority clinical trial designed to evaluate the safety and effectiveness of the magnesium-titanium hybrid intramedullary nail system compared with the marketed…
- Conditions
- Tibial Fracture, Femoral Fracture, Humeral Fracture
- Trial name
- NCT07569575
- Testing
- Magnesium-Titanium Hybrid Intramedullary Nail System, Commercially Locked Metallic Intramedullary Nail
- Where
- 5 sites in China
- Volunteers
- 160 people
- Sponsor
- HuaMg Perfection Med Tech (Suzhou) Co., Ltd.
Post Operative Pain
Comparison of Analgesic Efficacy of Suprainguinal Fascia Iliaca and Quadro-iliac Blocks in Hip Fracture Surgery
This prospective, randomized, double-masked trial compared two ultrasound-guided regional analgesic techniques, suprainguinal fascia iliaca block (SIFI) and quadro-iliac plane block (QIPB), in adults undergoing surgery for hip…
- Trial name
- NCT07546903
- Testing
- Suprainguinal Fascia Iliaca Block, Quadro-Iliac Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Hitit University
Hip Fractures, Analgesia
Comparison of the Efficiency of Femur Nerve Block and Intravenous Analgesia Treatment in Hip Fracture Patients
It is well-established that hip fractures impose a significant medical, socioeconomic, and financial burden. In the elderly population, the associated mortality and morbidity are particularly pronounced: within one year following…
- Conditions
- Hip Fractures, Analgesia, Femoral Nerve
- Trial name
- NCT06862154
- Testing
- IV Analgesia- Fentanyl, Femoral Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Marmara University
Hip Fractures, Knee Osteoarthritis
Effect of Remimazolam and Propofol on Postoperative Delirium
Remimazolam is an ultra-short acting benzodiazepine agonist which is used widely for general anesthesia and sedation. Remimazolam has several advantages.
- Conditions
- Hip Fractures, Knee Osteoarthritis, Femur Fracture
- Trial name
- NCT05514405
- Testing
- Remimazolam (Byfavo), Propofol
- Where
- South Korea
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Inje University
Femoral Neck Fractures
Comparison of the Direct Anterior Approach (DAA) and the Direct Lateral Approach (DLA) in Patients Treated With Partial Hip Replacement for Femoral Neck Fracture Based on Postoperative Functional Status
The goal of this clinical trial is to learn whether the surgical approach used for hemiarthroplasty can improve clinical and functional outcomes in adults with displaced femoral neck fractures.
- Trial name
- NCT07501741
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Hip Fractures
Effects of S-ketamine and Continuous Iliac Fascia Space Block on Perioperative Neurological Cognitive Impairment and Postoperative Rehabilitation in Elderly Patients With Hip Fracture
Elderly patients with hip fracture are older and have a high incidence of perioperative complications. the postoperative recovery of elderly patients with hip fracture is affected by hemodynamic instability and pain caused by…
- Trial name
- NCT05304559
- Testing
- S-Ketamine, Continuous iliac fascia space block, Normal saline
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Sarcopenia, Hip Fracture
Prevalence and Pathophysiology of Sarcopenia in the Elderly Patient With Hip Fracture
Sarcopenia is the loss of muscle mass and function that accompanies aging. The term sarcopenia comes from the Greek "sarx" (flesh) and "penia" (loss).
- Conditions
- Sarcopenia, Hip Fracture, Frailty
- Trial name
- PREFISSARC (NCT01477086)
- Where
- Spain
- Volunteers
- 198 people
- Sponsor
- Hospital Viamed Valvanera, Spain
Femoral Fractures
Dexmedetomidine and Bupivacaine With Bupivacaine in Ultrasonography Guided Fascia Iliaca Compartment Block in Adults
Few studies have reported the efficacy of adding dexmedetomidine to bupivacain for fascia illiaca compartment black. Comparison of dexmedetomidine and bupivacaine with bupivacaine alone on the quality of ultrasonography guided…
- Trial name
- NCT02658760
- Testing
- Dexmedetomidine, Bupivacaine
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Hamidreza Mahboobi
Pelvic Fracture
Pelvic Fractures in the Elderly
The aim of the project is to predict the patient under conservative therapy as a function of the patient Classification of Rommens and Hofmann and other potential prognostic factors.
- Trial name
- PelvFx (NCT03476824)
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Basel, Switzerland
Tibial Fracture
Safety of Spinal Anesthesia in Patients With Tibial Shaft Fracture
There is a elevated risk of acute compartment syndrome (ACS) related to tibial shaft fractures due to oedema and reduced blood flow in traumatised tissues. This may lead to lack of oxygen and even necrosis.
- Trial name
- NCT01795287
- Testing
- General anesthesia, Spinal anesthesia
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- University of Oulu
Hip Fractures, Stroke
Feasibility of the Geriatric Activation Program Pellenberg With Caregiver Involvement
This interventional study aims to see if involving caregivers as exercise partners with the physiotherapist throughout in-hospital geriatric rehabilitation and the first six weeks following discharge is feasible.
- Conditions
- Hip Fractures, Stroke, Frailty
- Trial name
- NCT05419284
- Testing
- GAPP+Care, +Care, Observation of GAPP+Care
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Hip Fractures, Hemodynamic Stability
Hemodynamic Safety of Levobupivacaine vs Bupivacaine in Patients Over 65 Years Undergoing Hip Surgery
The altered hemodynamics, and therefore the arterial hypotension is the most prevalent adverse effect after subarachnoid anesthesia.
- Trial name
- NCT03843970
- Testing
- Levobupivacaine Hydrochloride 0.5%, Isobaric bupivacaine 0.5%
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Hospital Clínico Universitario de Valencia
Proximal Tibia Fracture
The Efficacy and Cost Effectiveness of Preoperative and Postoperative Cryotherapy in Proximal Tibia Fractures
Consenting patients with proximal tibia fractures will be randomized to 10 degree or 21 degree cryotherapy sleeves. Time to discharge and complications will be monitored.
- Trial name
- ARCTIC CAT (NCT01104831)
- Testing
- Cryotherapy, Room temperature cuff
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Bleeding, Complications
Comparing Different Routes and Doses of Phytonadione (Vitamin K) for Reversing Warfarin Treated Patients With Hip Fracture Before Surgery
It is well known that femoral neck fractures carry a significant increase in patients' mortality and that surgical intervention is the preferred treatment.
- Trial name
- NCT00905229
- Testing
- Phytonadione
- Where
- Israel
- Sponsor
- HaEmek Medical Center, Israel
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