Clinical trials: Fracture of Lower Limb
Osteoporotic Fractures, Hip Fractures
Prediction and Secondary Prevention of Fractures
The purpose of this study is to investigate patient related factors that contribute to increased risk of recurrent fractures and to investigate patient adherence to prescribed anti-osteoporotic drugs.
- Conditions
- Osteoporotic Fractures, Hip Fractures, Wrist Fractures, Ankle Fractures
- Trial name
- NOFRACTsub (NCT02608801)
- Where
- 6 sites in Norway
- Volunteers
- 840 people
- Sponsor
- Oslo University Hospital
Patients With Fractures
Osteogenon in Orthopedics and Traumatology
The aim of this study was to evaluate the supportive effect of the ossein-hydroxyapatite complex in fracture healing. The investigators hypothesized that the ossein-hydroxyapatite complex would positively impact fracture healing…
- Trial name
- Osteogenon (NCT07210281)
- Testing
- received an ossein-hydroxyapatite complex
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- University of Opole
Old Age, Hip Fractures
Validity and Reliability of the Modified Delirium Diagnostic Tool - Provisional (DDT-Pro) (Thai Version) in Peri-operative Fragility Hip Fracture Patient
Nowadays, the number of hip fracture patients is increasing. As Thailand enters into an aging society, hip fractures are becoming more common. They are typically treated with surgery.
- Conditions
- Old Age, Hip Fractures, Delirium
- Trial name
- NCT06504251
- Testing
- Delirium Diagnostic Tool-Provisional ( DDT-Pro )
- Where
- Thailand
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Hip Fracture
Effects of Bisphosphonates and Nutritional Supplementation After a Hip Fracture
The study hypothesis is that nutritional supplementation together with bisphosphonates have a better preserving effect on bone mineral density (BMD) after hip fracture than bisphosphonates alone and that nutritional…
- Trial name
- NCT01950169
- Testing
- Risedronate, Nutritional supplement, Calcium and vitamin D3
- Where
- Sweden
- Volunteers
- 79 people
- Sponsor
- Karolinska Institutet
Femoral Neck Fractures
Femoral Neck Locking Plate Vs Multiple Cannulated Cancellous Screws in Treatment of Femoral Neck Fractures in Young Adults: Randomized Controlled Clinical Trial Study
Fracture neck femur are common injuries, especially seen in the elderly in the emergency setting. It is also seen in young patients with high-energy trauma.
- Trial name
- NCT06162637
- Testing
- femoral neck locking plate, multiple cannulated cancellous screws
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Eslam Mohamed AHmed
Left Ventricular Dysfunction, Femoral Fracture
Optimization Study of Cardiac Risk Patients With Hip Fracture
Elderly patients undergoing surgery for proximal hip fracture have a high risk of morbidity and mortality (M\&M) postoperatively.
- Trial name
- NCT01219712
- Testing
- Colloids, dobutamin, levosimendan
- Where
- 3 sites in Sweden
- Volunteers
- 200 people
- Sponsor
- University Hospital, Linkoeping
Ankle Fractures
Ziptight or Tricortical Screw Fixation of Acute Tibiofibular Syndesmotic Injury
Treatment of syndesmotic injury with Weber C fracture. A randomized study comparing ZipTight suture endobutton and one tricortical 3,5 mm syndesmotic screw.
- Trial name
- S16 (NCT02930486)
- Testing
- ZipTight suture endobutton, Tricortical 3.5 mm syndesmotic screw
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Vestre Viken Hospital Trust
Surgical Site Infection
PVI to Prevent S. Aureus SSI After Fixation of HELEF (POTENT Study)
The purpose of this study is to see whether applying povidone iodine (PVI) to the noses of patients undergoing lower extremity (leg, ankle, or foot) orthopedic fixation procedures of high-energy lower extremity fractures (HELEF)…
- Trial name
- POTENT (NCT05763602)
- Testing
- povidone-iodine topical ointment
- Where
- 6 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- Loreen Herwaldt
Femoral Fracture, Blood Pressure
Cerebral Oxygenation and Spinal Anaesthesia in Elderly Patients With Hip Fracture
The aim of this study is to observe how the hemodynamic changes induced by spinal blockade affect cerebral oxygenation. Elderly patients are very frail. Hypotension is very frequent during spinal anaesthesia.
- Conditions
- Femoral Fracture, Blood Pressure, Cognitive Impairment
- Trial name
- NCT01647230
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Hospital de Sabadell
Hip Fracture, Antithrombotic Therapy
Assessing the Effectiveness and Safety of Pericapsular Nerve Group (PENG) Block in Hip Fracture Patients on Antithrombotic Therapy
PENG block will be done on patients with hip fracture either receiving antithrombotic therapy or not under ultrasound guidance
- Conditions
- Hip Fracture, Antithrombotic Therapy, PENG Block
- Trial name
- PENG Block (NCT06582667)
- Testing
- PENG block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Ankle Injuries
Early Weightbearing and Mobilization Versus Non-Weightbearing and Mobilization in Unstable Ankle Fractures
The primary objective of the investigators randomized controlled trial is to determine if early protected weightbearing and ankle range of motion after surgical treatment (open reduction internal fixation - ORIF) for ankle…
- Trial name
- NCT01196338
- Testing
- Early weight-bearing and range of motion exercises, non-weight bearing, no range of motion
- Where
- 2 sites in Canada
- Volunteers
- 110 people
- Sponsor
- University of Toronto
EOS
Study of Residuals Deformities After Diaphyseal Femoral Fracture in Children Treated by Skin Traction
Diaphyseal femoral fracture in children <6 years old are treated by the skin traction technique. As demonstrated by numerous studies, given the significant potential for bone remodeling in young children, remodeling (excluding…
- Trial name
- FRAFEMKID (NCT06245993)
- Testing
- EOS imaging
- Where
- France
- Volunteers
- 53 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Elderly Patients, Malnutrition
Nutritional Intervention and Outcomes in Elderly After Hip Fracture Surgery
Hip fracture is one of the most frequently occurred injury in the elderly and usually requires surgical treatment. Malnutrition is common in elderly patients with hip fracture and is associated with worse outcomes.
- Conditions
- Elderly Patients, Malnutrition, Hip Fractures, Nutritional Intervention
- Trial name
- NCT04451538
- Testing
- Nutritional intervention group, Control group
- Where
- 3 sites in China
- Volunteers
- 30 people
- Sponsor
- Peking University First Hospital
Osteoarthritis (OA) of the Hip, Avascular Necrosis of Bone of Hip
MDR Vivacit-E Elevated Study
The main objective of this study is to confirm long-term safety, performance, and clinical benefits of the Vivacit-E Vitamin E HXLPE Elevated Liners when used in primary total hip arthroplasty.
- Conditions
- Osteoarthritis (OA) of the Hip, Avascular Necrosis of Bone of Hip, Protrusio Acetabuli, Traumatic Arthropathy-Hip
- Trial name
- NCT07150221
- Testing
- Vivacit-E Elevated Liners
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Zimmer Biomet
Hip Fracture, Vitamin D Deficiency
The Effect of Supplementation of Vitamin D Deficiency in Older People With Acute Hip Fracture:
This study will be done to evaluate the effect of load dose of vitamin D compared to the dose of usual clinical practice, in improving mobility and reducing disability in older people following a hip fracture.
- Trial name
- VITAMINA_D (NCT03213886)
- Testing
- Calcifediol (Vitamin D)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Leonor Cuadra Llopart
Femoral Neck Fractures
A Dose Finding Study for Pain Relief of a Broken Hip
Studies have suggested a link with effective pain relief and reduced illness and death in high risk patients. Ultrasound guided nerve blocks have been associated with an increased success rate and allow visualization of all the…
- Trial name
- NCT00926666
- Testing
- Levobupivacaine
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- NHS Greater Glasgow and Clyde
Hip Fractures, Anemia
The Effect of Preoperative Ferric Carboxymaltose Administration on Mortality in Geriatric Hip Fractures
Hip fractures (HF) are the most common and serious pathology affecting the hip and are associated with a high mortality risk in elderly patients.
- Conditions
- Hip Fractures, Anemia, Complication,Postoperative
- Trial name
- NCT06080893
- Testing
- Ferric carboxymaltose
- Where
- Turkey (Türkiye)
- Volunteers
- 209 people
- Sponsor
- Istanbul University
Femoral Neck Fractures, Internal Fixation
Three Cancellous Screws Versus Four Cancellous Screws for Femoral Neck Fixation
This study is a prospective randomized controlled clinical study. Patients with femoral neck fracture (AO classification 31-B) will be randomly divided into three-screw fixation group and four-screw fixation group.
- Trial name
- NCT04869332
- Testing
- three cancellous screws, four cancellous screws
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Peking University Third Hospital
Achilles Tendon Rupture, Ankle Fractures
Swedish Multicenter Trial of Outpatient Prevention of Leg Clots
Lower limb immobilization is associated with high risk of complications, i.e. venous thromboembolism (VTE) and failed healing. Pharmacoprophylaxis of VTE is in leg-immobilized patients, however, low- or non-effective and…
- Conditions
- Achilles Tendon Rupture, Ankle Fractures, Venous Thromboembolism
- Trial name
- StopLegClots (NCT03259204)
- Testing
- Adjuvant IPC
- Where
- Sweden
- Volunteers
- 1,400 people
- Sponsor
- Karolinska University Hospital
Hip Fracture
Statin in Hip Fracture
Statins (or HMG-CoA reductase inhibitors) have largely proven their efficacy in the primary and secondary prevention of cardiovascular events.
- Trial name
- STAFF (NCT01494090)
- Testing
- Rosuvastatin
- Where
- 6 sites in France
- Volunteers
- 36 people
- Sponsor
- University Hospital, Brest
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.