Clinical trials: Fractures, Spinal
Spinal Metastases
Trial of Combined Radiotherapy and Vertebroplasty for Patients With Painful Metastatic Spinal Lesions
Since patients with spinal metastases are living longer, durable palliation with long-term tumor control are becoming increasingly important. EBRT results in durable local control of bone metastasis.
- Trial name
- NCT04242589
- Testing
- Radiotherapy, Vertebropladty
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- AHS Cancer Control Alberta
Radius; Deformity, Hip Osteoarthritis
Clinical Evaluation and Cost-effectiveness Analysis of 3D Digital Surgery in Traumatology
Digital surgery, in combination with patient specific instrumentation (PSI) is being used more and more in traumatology due to its proven benefits and applications.
- Conditions
- Radius; Deformity, Hip Osteoarthritis, Hip Arthritis, Hip Arthropathy
- Trial name
- NCT06603831
- Testing
- patients treated using 3D technology and Patient-Specific Instrumentation, Patients treated with conventional surgery, without using 3D technology
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Corporacion Parc Tauli
Vertebral Body Fractures
Study on the Treatment of Osteoporotic Vertebral Fractures Using Vertebral Body Stenting
This is a randomized, controlled study to document and evaluate the clinical performance of the Vertebral Body Stenting (VBS) System in osteoporotic fractures of the thoracic and lumbar spine.
- Trial name
- NCT01847898
- Testing
- Vertebral Body Stenting (VBS), Balloon Kyphoplasty
- Where
- 5 sites in Austria, Germany
- Volunteers
- 100 people
- Sponsor
- Synthes GmbH
Hip Fracture
Comparison of Three Analgesic Strategies for Hip Fracture Surgery
Hip fracture surgery is associated with significant postoperative pain and increased opioid requirements. Regional anesthesia techniques may improve analgesia and reduce opioid consumption.
- Trial name
- HIP-3B (NCT07676734)
- Testing
- Quadro-Iliac Plane Block, Suprainguinal Fascia Iliaca Block, Standard Multimodal Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Femur Neck Fracture, Spinal Anesthesia
Comparison of Unilateral Spinal Anesthesia and Nerve Block in Hip Fractures
This randomized study aims to compare the efficacy and hemodynamic effects of hypobaric unilateral spinal anesthesia (HUSA) and lumbar plexus block (LP-SP) in patients undergoing femoral neck fracture surgery.
- Conditions
- Femur Neck Fracture, Spinal Anesthesia, Lumbar Plexus Nerve Block
- Trial name
- NCT07272226
- Testing
- Hipobaric Unilateral Spinal Anesthesia Group, Lumbar Plexus Block (LP-SP)
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Spine Fracture
Percutaneous Kyphoplasty Using Rotary Cutter in Osteoporotic Vertebral Fractures
Kyphoplasty(PKP) is performed under general anaesthesia in patients with osteoporotic vertebral compression fracture. The balloon is first placed into the fractured vertebra and inflated with contrast agent for height…
- Trial name
- NCT03850938
- Testing
- Conventional Kyphoplasty, Kyphoplasty with Rotary Cutter
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Li Min
Hip Fractures, Anesthesia
Fractional Spinal Anesthesia and Systemic Hemodynamics in Frail Elderly Hip Fracture Patients.
Aging and frailty make the elderly patients susceptible to hypotension following spinal anaesthesia. The systemic haemodynamic effects of spinal anaesthesia are not well known.
- Conditions
- Hip Fractures, Anesthesia, Hypotension Drug-Induced, Cardiac Output, Low
- Trial name
- NCT05101291
- Testing
- Bupivacain
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Sahlgrenska University Hospital
Osteoporosis, Postmenopausal
Effects of Arzoxifene on Bone Fractures and Incidence of Breast Cancer
The purpose of this trial is to study: Effects of arzoxifene on bone fractures and bone mass. Effects of arzoxifene on getting breast cancer.
- Trial name
- NCT00088010
- Testing
- Arzoxifene
- Where
- United States
- Volunteers
- 9,369 people
- Sponsor
- Eli Lilly and Company
Spine Fracture, Osteoporosis
Controlled Reduction of AO Spine B3 Fractures in Ankylosing Spinal Disorders Using an Inflatable Positioning Device: Technical Note and Retrospective Single-centre Case Series
Retrospective observational
- Conditions
- Spine Fracture, Osteoporosis, Spondylitis, Ankylosing
- Trial name
- NCT07847320
- Volunteers
- 23 people
- Sponsor
- Diakonie-Klinikum Stuttgart
Osteoporosis, Vertebral Fracture
A Trial of Vertebroplasty for Painful Chronic Osteoporotic Vertebral Fractures (Vertos V)
Background The standard care in patients with a painful osteoporotic vertebral compression fracture (VCF) is conservative therapy.
- Trial name
- VERTOSV (NCT01963039)
- Testing
- percutaneous vertebroplasty
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Elisabeth-TweeSteden Ziekenhuis
Disc Degenerative Disease, Spondylolisthesis
A Clinical Study of a Spine Fusion System in Vertebral Body Fusion Surgery
The primary objective of this study is to demonstrate that the efficacy and safety of Spine fusion system manufactured in China is no inferior than imported product.
- Conditions
- Disc Degenerative Disease, Spondylolisthesis, Spinal Fracture, Spinal Deformity
- Trial name
- NCT02252185
- Testing
- Johnson&Johnson Medical Suzhou made Spine Fusion System, Imported EXPEDIUM screws and OPAL cage
- Where
- 8 sites in China
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Medical (Suzhou) Ltd.
Spinal Fractures
Study to Investigate the Long Term Survivorship of Coflex
Examine the long-term survivorship via CT Scan of the coflex in patients who presented with spinous process fracture(s) at 24 months in the Paradigm Spine coflex IDE Study.
- Trial name
- NCT02918669
- Testing
- CT Scan
- Volunteers
- 12 people
- Sponsor
- Paradigm Spine
Spinal Fractures
Effect and Essentiality of Vertebroplasty Surgery in Acute Vertebral Compression Fractures
Percutaneous vertebroplasty is now a common procedures of patients with acute osteoporotic vertebral compression fractures in medical units all over China, but the efficacy and essentiality of the surgery remain uncertain and is…
- Trial name
- NCT03360383
- Testing
- percutaneous vertebroplasty, conservative treatment
- Volunteers
- 400 people
- Sponsor
- Peking University People's Hospital
Vertebral Fracture, Balance
Evaluation of Balance and Gait Weight Distribution in Patients With Vertebral Column Fractures
Vertebral column fracture presents a significant warning of subsequent osteoporotic fracture and frequent falls. The presence of an osteoporotic vertebral fracture is also a predictor of further risk of vertebral and other…
- Conditions
- Vertebral Fracture, Balance, Gait, Unsteady
- Trial name
- NCT05010135
- Testing
- Zebris Gait System assessment for gait weight distribution + EMG evaluation of Quadriceps, Hamstrings, Tib Anterior and Calves + Positional Sense assessment
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Tung Wah College
Osteoporosis
Addressing Vertebral Osteoporosis Incidentally Detected to Prevent Future Fractures
Osteoporosis is a common and progressive condition that leads to broken bones (fractures), which cause pain, disability, deformity, and even death.
- Trial name
- AVOID Fracture (NCT00388908)
- Testing
- Reminders and opinion leader generated guidelines +/- leaflets and counselling, Usual Care
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- University of Alberta
Failed Lumbar Fusion
Study on Allogeneic Osteoblastic Cells Implantation in Rescue Interbody Fusion
Failed fusion and failure to relieve back pain following spinal fusion are still frequent, irrespective of the type of procedures or grafts used by the surgeon.
- Trial name
- NCT02328287
- Testing
- ALLOB®
- Where
- 3 sites in Belgium
- Volunteers
- 6 people
- Sponsor
- Bone Therapeutics S.A
Kyphosis, Spinal Fractures
Intra-operative Assessment of the Intellirod LOADPRO Spinal Rod Strain Sensor for Use During Kyphotic Corrective Surgery
The LOADPRO Study is an intra-operative, non-significant risk (NSR) case series feasibility assessment of the Intellirod LOADPRO™ System measuring spinal rod strain in long spinal kyphotic corrective constructs.
- Trial name
- LOADPRO (NCT02768675)
- Testing
- LOADPRO
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Intellirod Spine
Lumbar Spinal Stenosis, Lumbar Disc Herniation
In Turkish Version Lumbar Spine Surgery Expectation Survey
The aim of this study was to determine the Turkish validity and reliability of Lumbar Spine Surgery Expectations Survey developed by Mancuso.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Radiculopathy, Lumbar Fracture
- Trial name
- NCT04547075
- Testing
- Turkish validity and reliability
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Kutahya Health Sciences University
Femur Fracture, Hip Surgery
Pericapsular Nerve Group (PENG) Block on Pain During Participant Positioning for Spinal Anesthesia in Hip Fracture Surgery
Hip fracture surgery is a common orthopedic procedure, especially in elderly patients. These fractures are quite common in adults over the age of 65, and the one-year mortality rate ranges from 12% to 37%.
- Trial name
- NCT06813755
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Marmara University
Vertebral Fracture, Compression Fracture
Spine Bone Cements Outcomes - Post Market Follow-up
A Post-Market Clinical Follow-Up (PMCF) Study to collect clinical data on safety and performance of all TEKNIMED Spine range of products: SPINEFIX, HIGH V+, OPACITY+ and F20 bone cements and mixing and injection systems, and all…
- Conditions
- Vertebral Fracture, Compression Fracture, Osteoporotic Fractures
- Trial name
- NCT06367582
- Testing
- Vertebroplasty (VP), Kyphoplasty (KP), Pedicular Screw Augmentation (PSA)
- Where
- 12 sites in France, Portugal and 2 more
- Volunteers
- 500 people
- Sponsor
- Teknimed