Clinical trials: Fractures, Spinal
Hip Fracture, Analgesia
Ultrasound Percapsular Nerve Group Block VS Fascia Iliaca Block for Hip Fracture
Spinal anesthesia (SA) is a widely accepted anesthetic technique for hip fracture repair among elderly. Positioning for SA can be extremely painful. Effective management of pain is important for these patients comfort.
- Conditions
- Hip Fracture, Analgesia, Acute Pain
- Trial name
- NCT04285333
- Testing
- fascia iliaca block, percapsular nerve group block
- Where
- Tunisia
- Volunteers
- 88 people
- Sponsor
- University Tunis El Manar
Osteoporosis, Postmenopausal
Motor Control Exercise in Osteoporotic Women
The objective of this study was to explore the effectiveness of Motor Control Exercise on pain, postural alignment and spinal curvatures in women with osteoporotic vertebral fractures.
- Trial name
- NCT01172574
- Testing
- Motor control exercise
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- National and Kapodistrian University of Athens
Back Pain
The Effect of PTH(1-84) or Alendronate on Reduction of Back Pain in Postmenopausal Women With an Osteoporosis Related Vertebral Fracture(s) (FP-005-IM)
The primary objective of this trial is to show that PTH(1-84) is superior to alendronate in reducing back pain intensity over a 24-week treatment period in postmenopausal women with an osteoporosis related vertebral fracture(s).
- Trial name
- NCT00713258
- Testing
- Parathyroid hormone (PTH) (1-84), Alendronate
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Nycomed
Vertebral Fracture, Osteoporosis
A Prospective Observational Study of Artificial Intelligence Morphometric Evaluation of Vertebral Fractures
The study will be conducted as a monocentric observational prospective study design wants to evaluate the prevalence of vertebral fractures in the cohort of patients that perform a chest-abdomen CT for medical indication other…
- Trial name
- NCT06449742
- Testing
- AI software and automatic 3D reconstruction
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- IRCCS San Raffaele
Fracture of Proximal End of Femur
Comparison of Analgesic Effectiveness of Intravenous Ketamine and Fentanyl for Spinal Anesthesia is Sitting Position in Patients With Proximal Femur Fracture
This is a prospective comparative study which will be conducted in patients with proximal femur fracture undergoing operative interventions under subarachnoid block in sitting position.
- Trial name
- NCT04418674
- Testing
- Ketamine, Fentanyl
- Where
- 2 sites in Nepal
- Volunteers
- 52 people
- Sponsor
- Jenny Bajracharya
Thoracic Spine Fracture, Lumbar; Spine, Fracture
Effectiveness of Conservative Treatment in Patients With Thoracic and Lumbar Fractures Without Neurological Deficit
The goal of this observational study is to compare the long-term clinical outcomes of two treatment methods (conservative therapy and surgical treatment) in patients with fractures of the thoracic and lumbar spine without…
- Conditions
- Thoracic Spine Fracture, Lumbar; Spine, Fracture, Thoracolumbar Burst Fracture, Fracture of Spine, Level Unspecified
- Trial name
- NCT06059820
- Testing
- rehabilitation treatment, Spine fusion
- Where
- 2 sites in Russia
- Volunteers
- 40 people
- Sponsor
- Sklifosovsky Institute of Emergency Care
Osteoporosis, Hyperkyphosis
Relationship Between Thoracic Hyperkyphosis and Fall Risk in Women with Fragility Vertebral Fractures
Multiple vertebral fragility fractures, one of the main complications of osteoporosis, are frequently associated with thoracic hyperkyphosis, which in turn leads to significant postural alterations.
- Conditions
- Osteoporosis, Hyperkyphosis, Vertebral Body Fracture
- Trial name
- NCT06842758
- Testing
- Rehabilitation Treatment, None Treatment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Palermo
Osteoporosis, Interstitial Lung Disease
Opportunistic Screening for Osteoporotic Vertebral Fractures in Patients With Diffuse Interstitial Lung Disease
It is well known that some chronic respiratory pathologies such as asthma or chronic obstructive pulmonary disease (COPD) are associated with an increased risk of osteoporosis, due to the pathology itself and the therapies…
- Conditions
- Osteoporosis, Interstitial Lung Disease, Vertebral Fracture
- Trial name
- NCT05714787
- Testing
- Chest CT Scan examination
- Where
- France
- Volunteers
- 202 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
SPINAL Fracture
Incidence of Metal Failure During First Year Following Transpedicular Screws Fixation of Dorsolumbar Spine Fracture
Recording incidence of metal failure in transpedicular screws fixation of dorsal umbra spine fracture during first year follow up
- Trial name
- NCT03312998
- Testing
- Xrays
- Volunteers
- 100 people
- Sponsor
- Assiut University
Sickle Cell Disease, Sickle Cell Anemia
Sickle Cell Disease (SCD) Bone Pain Study
A prospective study to determine how low bone mineral density and/or vertebral compression fractures associate with pain in adults with sickle cell disease
- Conditions
- Sickle Cell Disease, Sickle Cell Anemia, Low Bone Density, Osteoporosis
- Trial name
- NCT05283148
- Testing
- Dual-energy X-ray absorptiometry, Vertebral fracture analysis, Adult Sickle Cell Quality of Life Measurement System pain impact questionnaire
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of California, Davis
Acute Spinal Cord Injury, Acute Spinal Paralysis
Canadian-American Spinal Cord Perfusion Pressure and Biomarker Study
This multicenter study will enroll 100 patients with acute traumatic cervical and thoracic SCI who have a lumbar intrathecal catheter inserted within 24 hours of their injury.
- Conditions
- Acute Spinal Cord Injury, Acute Spinal Paralysis, Spinal Cord Injuries, SPINAL Fracture
- Trial name
- CASPER (NCT03911492)
- Testing
- SCPP Management => 65 mmHg
- Where
- 8 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Pathological Fracture of Vertebra Due to Secondary Osteoporosis (Disorder), Pathological Fracture of Vertebra Due to Neoplastic Disease (Disorder)
Xpede Clinical Study
The purpose of this clinical study is to confirm the efficacy and safety of the Kyphon®Xpede™ Bone Cement in human use in China.
- Trial name
- NCT03730207
- Testing
- Xpede™ Bone Cement, Mendec Spine Bone Cement
- Where
- 3 sites in China
- Volunteers
- 180 people
- Sponsor
- Medtronic Spinal and Biologics
Osteoporosis, Vertebral Fracture
Study of Effect of Exercise With Osteoporosis and Vertebral Fracture
The aim of this randomized controlled trial is to evaluate the effectiveness for health-related quality of life (HRQOL) of a 3-month course of exercises for a group of postmenopausal women with osteoporosis who has at least one…
- Trial name
- NCT01120197
- Testing
- Exercise group, Control Group
- Where
- Norway
- Volunteers
- 89 people
- Sponsor
- Ostfold Hospital Trust
Lower Extremity Fracture
Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb Surgeries
A study to compare between intravenous atropine and glycopyrrolate in preventing spinal anesthesia induced hypotension in patients undergoing major lower limb orthopedic surgeries.
- Trial name
- NCT03580889
- Testing
- Atropine, Glycopyrrolate, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Nepal
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Vertebral Fracture
Prevalence of Subclinical Vertebral Fractures in Rheumatoid Arthritis and Ankylosing Spondylitis
Study of prevalence of subclinical vertebral fractures in Rheumatoid Arthritis and Ankylosing spondylitis
- Trial name
- NCT06092775
- Testing
- DEXA scan,X_ray
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Assiut University
Spinal Fractures, Vertebral Compression Fractures
SpineJack® Versus Conservative Treatment Study (SPICO Study)
This study will compare two standard treatments in acute stable traumatic vertebral fractures (types A1 and A3.1 by Magerl Classification). The two treatments are as follows: 1. SpineJack® system 2.
- Conditions
- Spinal Fractures, Vertebral Compression Fractures, Back Injuries, Trauma
- Trial name
- NCT02657265
- Testing
- SpineJack system, Conservative management
- Where
- 9 sites in France
- Volunteers
- 100 people
- Sponsor
- Vexim SA
Hip Fracture Surgeries
FASCIA ILIACA BLOCK VERSUS INTRAVENOUS NALBUPHINE AS ANALGESIC METHOD BEFORE POSITIONING FOR SPINAL ANESTHESIA IN PATIENTS UNDERGOING SURGERY FOR HIP FRACTURES
Investigators will compare FASCIA ILIACA BLOCK VERSUS INTRAVENOUS NALBUPHINE AS ANALGESIC METHOD BEFORE POSITIONING FOR SPINAL ANESTHESIA IN PATIENTS UNDERGOING SURGERY FOR HIP FRACTURES
- Trial name
- NCT07613801
- Testing
- Bupivacain, Nalbuphine
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Liaquat National Hospital & Medical College
Multiple Myeloma
Health-Related Quality of Life (QOL), Physical and Respiratory Function in Patients With Myeloma Affecting the Spine
The purpose of this study is to create a prospective database of patients with myeloma affecting the spine. This database will define changes in health-related quality of life over time, and the effect of incident fractures and…
- Trial name
- NCT01006070
- Testing
- kyphoplasty
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Vertebral Fracture
Anesthesia Methods on Percutaneous Kyphoplasty
The aim of this research is to examine the effects of the anesthesia method and preoperative characteristics on postoperative results and complications in patients who underwent percutaneous kyphoplasty (PKP).
- Trial name
- NCT05526794
- Testing
- Analgesic consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Spinal Fractures, Osteoporosis
Vertebroplasty for the Treatment of Fractures Due to Osteoporosis
Vertebroplasty is a procedure used to stabilize broken vertebrae, the bones that form the spine. This study will evaluate the effectiveness of vertebroplasty for the treatment of fractures due to osteoporosis.
- Trial name
- NCT00068822
- Testing
- Percutaneous vertebroplasty
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- Mayo Clinic