Clinical trials: Fractures, Spinal
Ankylosing Spondylitis, Spinal Fractures
Effect of Biological Disease Modifying Anti Rheumatic Drug (bDMARD) Treatment on Spinal Fracture Incidence in Patients With Ankylosing Spondylitis (AS)
Ankylosing spondylitis (AS) is a rheumatoid disease affecting all segments of the axial skeleton, leading to the complete fusion of all spinal segments - the bamboo-spine.
- Trial name
- NCT02840695
- Testing
- bDMARD treatment
- Volunteers
- 9,858 people
- Sponsor
- Uppsala University
Vertebral Fracture, Kyphoplasty
Porous Titanium Microspheres in Kyphoplasty
Study is a prospective observational, performed in the context of normal clinical practice, of patients with osteoporotic vertebral compression fractures identified as candidates for kyphoplasty treatment with porous trabecular…
- Trial name
- NCT05815251
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Unit of neurosurgery, Departement of Neurosciences, University of Torino
Healthy, Osteopenia
Clinical Study to Predict the Risk of Bone Fractures With the POROUS Ultrasound Device
Osteoporosis is a widespread medical condition among older people. It causes the bones to weaken and become more likely to break.
- Conditions
- Healthy, Osteopenia, Osteoporosis
- Trial name
- POROUS-preFX (NCT06567054)
- Testing
- Measurements with the POROUS R3C ultrasound device at the midshaft tibia, DXA measurement of the hip and lumbar spine, DXA-based Vertebral Fracture Assessment (VFA)
- Where
- 6 sites in Austria, Germany and 1 more
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- POROUS GmbH
Spinal Anesthesia, Hip Fractures
Peri-Capsular Nerve Group and Supra Inguinal Fascia Iliaca BLOCK for Analgesia and Ease of Positioning During Neuraxial Anesthesia in Hip Fracture Patients
Severe pain associated with fractured hip often results in difficulty during positioning for spinal anesthesia (SA). Among many regional analgesic techniques, the fascia iliaca compartment block (FICB) is popular among…
- Trial name
- NCT05987254
- Testing
- suprainguinal fascia iliaca block, pericapsular nerve group block
- Where
- 3 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Cervical Spine Fracture
Mid-Term Outcomes Of Fracture Odontoid Management in Assiut University
The aim of this study is to evaluate and assess the mid-term outcomes of treating odontoid fracture cases admitted to the Trauma Unit of Assiut University Hospital.
- Trial name
- NCT05842694
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Assiut University
Efficiency, Spinal Anesthesia
The Efficiency of Preoperative Pericapsular Nerve Group Block Applied With Ultrasound and Success of Spinal Anesthesia
We aimed to investigate the effectiveness of the pericapsular nerve group (PENG) block applied with preoperative ultrasonography (USG) in patients who were operated on under spinal anesthesia due to hip fracture and whether it…
- Conditions
- Efficiency, Spinal Anesthesia, Block
- Trial name
- PENG (NCT06209372)
- Testing
- Group PENG, Group C
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Suleyman Demirel University
Pseudoarthrosis, Spinal Stenosis
A Study Comparing Fusion Rates of Two Lumbar Fusion Procedures
The purpose of this study is to demonstrate the relative efficacy of two lumbar fusion procedures: transacral lumbar interbody fusion when used in conjunction with unilateral or bilateral posterior pedicle screw fixation as an…
- Conditions
- Pseudoarthrosis, Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease (DDD)
- Trial name
- NCT01972256
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- Baxano Surgical, Inc.
Vertebral Fracture, Multiple Myeloma
Treatment of Malignant Vertebral Fractures With Percutaneous Balloon Kyphoplasty.
Balloon Kyphoplasty is an alternative to vertebroplasty in the treatment of painful malignant vertebral fractures. This is a mini-invasive percutaneous treatment, aiming to stabilize the vertebral fracture, decrease of pain.
- Conditions
- Vertebral Fracture, Multiple Myeloma, Osteolytic Metastases
- Trial name
- KYPHOK (NCT00748631)
- Testing
- balloon kyphoplasty
- Where
- 4 sites in France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteoporosis, Fracture Risk Assessment
Five-Year CT Follow-Up of Vertebral Fracture Risk Using Opportunistic Osteoporosis Screening
This study evaluates whether opportunistic osteoporosis screening using routinely acquired computed tomography (CT) scans improves fracture risk prediction compared with guideline-recommended FRAX-based screening from age 50.
- Conditions
- Osteoporosis, Fracture Risk Assessment, Osteoporotic Fracture of Vertebra
- Trial name
- NCT07487688
- Testing
- Opportunistic osteoporosis screening
- Where
- Germany
- Volunteers
- 2,799 people
- Sponsor
- Technical University of Munich
Femur Fracture, Peripheral Nerve Block
Peripheral Nerve Blocks vs Selective Spinal Anesthesia in Patients With Femur Fracture
Proximal Femur Fractures (PFF) represent one of the most common orthopedic injuries worldwide, affecting especially elderly patients with potentially disabling outcomes and a marked impairment of quality of life.
- Conditions
- Femur Fracture, Peripheral Nerve Block, Spinal Anesthesia
- Trial name
- NCT06155903
- Testing
- Selective Spinal Anesthesia, Peripheral nerve blocks, Anesthesiological mixtures (Spinal anesthesia)
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- Federico II University
Lung Edema, Hip Fractures
Ultrasound in Evaluation of Preoperative Fluid Management of Hip Fracture Surgery Patients
Goal directed fluid therapy is a new standard surgical procedure which is successful in patients undergoing hip revision arthroplasty, There has been a reduction of postoperative complications, most importantly surgery with a…
- Trial name
- NCT05916599
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Cervical Vertebra Injury, Cervical Vertebra Fracture
Three Instructional Interventions for Prehospital Cervical Spinal Immobilization by Laypeople
It is not known if bystanders equipped with point-of-care (POC) instruction are as effective as bystanders with in-person training for c-spine immobilization.
- Trial name
- NCT05359575
- Testing
- Audio kit, Instructional flashcard (version 1), In-person training
- Where
- United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Male Osteoporosis
Efficacy in Reducing Fractures and Safety of Zoledronic Acid in Men With Osteoporosis
This study will investigate if the drug zoledronic acid given once yearly is safe and has beneficial effects in treating osteoporosis by reducing bone loss and fractures in men with osteoporosis.
- Trial name
- NCT00439647
- Testing
- Zoledronic acid 5 mg iv
- Where
- 128 sites in Argentina, Australia and 21 more
- Volunteers
- 1,199 people
- Sponsor
- Novartis Pharmaceuticals
Spine Fracture, Degenerative Disc Disease
Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Cervical
Multicenter Post market clinical follow-up Study on the Safety and Performance of Ennovate® Cervical - Prospective, pure data collection of all Ennovate Cervical patients in Total Indications
- Conditions
- Spine Fracture, Degenerative Disc Disease, Spinal Instability, Spinal Tumor
- Trial name
- CERISE (NCT05296889)
- Testing
- posterior stabilization for the cervical spine
- Where
- 4 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Aesculap AG
Spinal Fracture, Spinal Injuries
Pre-therapeutic Value of Emergency Spine MRI in Patients With Thoraco-lumbar Spine Injuries - A Prospective Study.
The main objective is to determine whether the realisation of an emergency spine MRI in addition to CT-scan( Computed Tomography) in patients with thoraco-lumbar spine injuries changes the therapeutic management.
- Conditions
- Spinal Fracture, Spinal Injuries, Wounds and Injuries
- Trial name
- NCT07265310
- Testing
- Clinical value of spine MRI in therapeutic management of patients admitted for thoraco-lumbar spine injuries, in addition to ct-scan.
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Metastatic Cancers, Multiple Myeloma
Vertebral Augmentation and Radiotherapy of Collapse Spinal Metastatic Cancer
Vertebral augmentation with radiotherapy to increase the functional status and quality of life for patients with vertebral body metastatic cancers.
- Conditions
- Metastatic Cancers, Multiple Myeloma, Vertebral Fracture
- Trial name
- NCT02376933
- Testing
- Vertebroplasty, Radiotherapy
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Arizona
Hip Fractures
Combined Plexus Block for Hip Fracture Surgery.
Hip fracture surgery requires high risk anesthetic procedure for elderly patients (1). General anesthesia, continuous spinal anesthesia and peripheral nerve blocks are three anesthetic techniques possible.
- Trial name
- NCT03356704
- Testing
- no intervention
- Volunteers
- 593 people
- Sponsor
- University Hospital, Montpellier
Postmenopausal Osteoporosis, Spinal Fractures
Epidemiology, Identification Rate and Treatment Penetration of Osteoporotic Vertebral Fractures in Switzerland
In Switzerland, the prevalence of vertebral fractures in community- dwelling women is unknown and the published data from the Swiss hospitals statistics represent only the tip of the iceberg.
- Trial name
- SwOF (NCT02234414)
- Where
- 3 sites in Switzerland
- Volunteers
- 303 people
- Sponsor
- Prof. Dr. med. Kurt Lippuner
Osteopenia, Kyphosis
Effects of the "Spinomed Active" Orthosis on Chronic Back Pain in Women With Vertebral Fractures.
Osteoporotic vertebral fractures often lead to postural changes, chronic spinal pain conditions and limited functionality. Orthoses that straighten the spine have been shown in studies to have a positive effect on pain, posture…
- Trial name
- NCT04854629
- Testing
- Spinomed active
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Spinal Fractures
Survival After Surgical Treatment of Axis Fractures in Elderly
Fractures of the second cervical vertebra (C2) are the most common spinal fracture among the elderly. Non-surgical treatment comprises of cervical collar treatment for 12 weeks, while surgical treatment for elderly could mean…
- Trial name
- NCT02839057
- Testing
- Non-surgical treatment, Surgical treatment
- Volunteers
- 6,231 people
- Sponsor
- Uppsala University