Clinical trials: Fractures, Spinal
Hip Fractures, Acute Post Operative Pain
PENG vs SIFI Block for Positioning Pain During Spinal Anesthesia
This study aims to compare the effectiveness of preoperative ultrasound-guided suprainguinal fascia iliaca compartment block (SFICB) and pericapsular nerve group block (PENG) in preventing positioning pain during spinal…
- Conditions
- Hip Fractures, Acute Post Operative Pain, Nerve Block, Spinal Anesthesia
- Trial name
- NCT05549011
- Testing
- PENG Block, SIFI compartment block, Numeric Rating Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Spinal Cord Injuries, Spinal Injuries
DBS of PPN to Improve Walking in Chronic SCI Patients
Spinal cord injury (SCI) is a devastating condition affecting over 1 million individuals in North America. SCI often results in severe motor impairments with few available treatments options.
- Conditions
- Spinal Cord Injuries, Spinal Injuries, Spinal Fractures
- Trial name
- NCT04325165
- Testing
- DBS Implantation
- Sponsor
- University Health Network, Toronto
Osteoporosis, Vertebral Fracture
Chiropractor Delivered Virtual Intervention After Vertebral frActure
This study will determine feasibility of a chiropractor delivered virtual intervention for individuals following osteoporotic vertebral fracture. This pilot trial will have two parallel groups with a 1:1 ratio.
- Trial name
- VIVA (NCT07288684)
- Testing
- VIVA
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Waterloo
Hip Fracture
Analgesia for Positioning Hip Fracture Patients for Spinal Anesthesia
The purpose of this study is to compare two analgesic methods performed preoperatively to assist positioning patients for performance of spinal anesthesia, namely fascia iliaca blockade and intravenous fentanyl.
- Trial name
- NCT02037633
- Testing
- Fentanyl, Fascia iliaca compartment block, ropivacaine
- Where
- Greece
- Volunteers
- 41 people
- Sponsor
- Asklepieion Voulas General Hospital
Vertebral Compression Fractures, Pathological Fracture
Prospective Evaluation of Therapeutic Combination in Treating Vertebral Compression Fractures
The purpose of this study is to collect clinical and radiographic outcomes in patients undergoing vertebroplasty procedures for the treatment of osteoporotic or pathological fractures of the vertebral body to understand the role…
- Conditions
- Vertebral Compression Fractures, Pathological Fracture, Facet Joint Arthropathy
- Trial name
- PROTECT (NCT06670404)
- Testing
- Vertebroplasty
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Prof Nicolas Theumann
Diabetes Mellitus, Type 1, Bone Fracture
Prevalence of Vertebral Fractures in Patients With Type 1 Diabetes
Background : Type 1 diabetes is associated with an increased risk of fractures. The mechanisms accounting for this bone fragility are not yet fully understood.
- Conditions
- Diabetes Mellitus, Type 1, Bone Fracture, Bone Health
- Trial name
- DenSiFy (NCT04064437)
- Testing
- Clinical tests, Biochemical tests, DXA scan
- Where
- 2 sites in Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Hip Fractures
Total Hip Arthroplasty Instability and Lumbo-pelvic Kinematics: EOS Imaging Assessment of Variation in Spinal and Pelvic Parameters From Standing to Sitting
The authors hypothesize that a pelvic kinematic disorder, demonstrated by a significant decrease in sacral slope, is associated with the risk of instability of total hip prosthesis, the sacral slope being measured by an EOS…
- Trial name
- HIPEOS (NCT03603470)
- Testing
- EOS imagery
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Femur Fracture, Spinal Anesthesia
Echocardiography Examination Of The Cardiac Effects Of Different Regional Anesthesia Methods
Nerve blocks applied with neuraxial anesthesia and ultrasonography are used for many operations today. Neuraxial blocks cause varying degrees of decrease in the blood pressure level of the patients.
- Conditions
- Femur Fracture, Spinal Anesthesia, Lumbar Plexus Block
- Trial name
- NCT04975386
- Testing
- Transthoracic echocardiogram
- Volunteers
- 62 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Hip Fractures, Spinal Anesthesia
The Effect of Spinal Column Flexion on Unilaterality of Spinal Anesthesia
The effect of two different positions on spinal anesthesia in hip fracture surgery
- Trial name
- NCT06293404
- Testing
- Bupivacain
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
SMA - Spinal Muscular Atrophy
Adrenal& Bone Complications in Paediatric Patients Living With Spinal Muscular Atrophy (SMA)
Spinal muscular atrophy (SMA) is a genetic disorder that is known to cause damage to specialised nerve cells, called motor neurons.
- Trial name
- SMA-ABC (NCT07530926)
- Where
- United Kingdom
- Volunteers
- 550 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Elective Posterior Lumbar Spinal Fusion for Spinal Stenosis, Spondylolisthesis
Assessing the Diagnostic Accuracy of Corrected Flow Time (FTc) and Pleth Variability Index (PVI) as Predictors of Fluid Responsiveness in Patients in the Prone Position Using the Jackson Table
Appropriate fluid management is an important part of anesthesia in patients undergoing surgery, and several dynamic indices have been suggested to have high predictability for fluid responsiveness in patients receiving mechanical…
- Conditions
- Elective Posterior Lumbar Spinal Fusion for Spinal Stenosis, Spondylolisthesis, Spinal Fractures, Scoliosis or Tumors
- Trial name
- NCT02826889
- Testing
- Philips Intelivue MP70 monitor, Pleth Variability Index (PVI)
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
Rheumatoid Arthritis, Osteoporosis
Efficacy of Monthly Ibandronate in Women With RA and Reduced Bone Mineral Density Receiving Long-term Steroids
This study was to investigate the efficacy of oral monthly ibandronate in the management of glucocorticoid induced osteoporosis in women with rheumatoid arthritis.
- Conditions
- Rheumatoid Arthritis, Osteoporosis, Osteopenia
- Trial name
- NCT01287533
- Testing
- Ibandronate
- Where
- South Korea
- Volunteers
- 167 people
- Sponsor
- Yeong-Wook Song
Spinal Cord Injury, Bone Loss
Effect of Alendronate on Bone in People With Chronic Spinal Cord Injury (SCI) Previously Treated With Teriparatide
The purpose of this study is to determine if a year of alendronate treatment will maintain or increase bone mass density (BMD) compared to baseline BMD values in people with chronic spinal cord injury (SCI).
- Conditions
- Spinal Cord Injury, Bone Loss, Osteoporosis
- Trial name
- NCT02195895
- Testing
- Alendronate, Calcium, Vitamin D
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Northwestern University
Pain
A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)
The purpose of this study is to see if changing from one pain medication like morphine or oxycodone to another pain medication, oxymorphone (OPANA®), will be helpful to patients.
- Trial name
- NCT00580294
- Testing
- Oxymorphone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Degenerative Lumbar Spinal Stenosis, Degenerative Spondylolisthesis
Clinical Evaluation of Orion Lamina Cover in Patients Undergoing Lumbar Laminectomy With Instrumented Fusion
Laminectomy with internal fixation and osseofusion is a common surgery for treating degenerative spinal diseases. It removes excessive bone spurs and removes the lamina for decompression to relieve nerve compression, and then…
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Spondylolisthesis, Spinal Stenosis, Scoliosis
- Trial name
- NCT06532968
- Testing
- ORION spinal lamina cover
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Orion Biotech Inc.
Postmenopausal Osteoporosis, Vertebral Fracture
How Vertebral Fractures Effect Balance In Postmenopausal Women
Osteoporosis is defined as low bone mineral density caused by altered bone microstructure, ultimately predisposing patients to fragility fractures.
- Conditions
- Postmenopausal Osteoporosis, Vertebral Fracture, Fracture of Vertebra, Fall
- Trial name
- NCT06502301
- Testing
- Cross-sectional study
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Istanbul University - Cerrahpasa
Spinal Cord Injuries (SCI), Osteoporosis
Osteoporosis Awareness in Chronic Spinal Cord Injury
Osteoporosis is a common and serious complication of spinal cord injury (SCI), substantially increasing the risk of fragility fractures.
- Conditions
- Spinal Cord Injuries (SCI), Osteoporosis, Health Knowledge, Attitudes
- Trial name
- NCT07725081
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Afyonkarahisar Health Sciences University
Vertebral Fracture, Cement Augmentation
Assessing Cement-bone Incorporation and Adjacent Segment Degeneration Following Cement Augmentation; an MRI-PET Follow-up
3-year PET-MRI follow-up after vertebral balloon kyphoplasty aiming to investigate cement incorporation.
- Trial name
- NCT03369288
- Testing
- PET MRI
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Spinal Fracture, Osteoporosis
Quality of Life After Vertebroplasty Versus Conservative Treatment in Patients With Painful Osteoporotic Vertebral Fractures
The purpose of this study is to determine whether percutaneous vertebroplasty is able to improve long-term quality of life in patients with pain secondary to osteoporotic vertebral fractures, compared to conventional medical…
- Conditions
- Spinal Fracture, Osteoporosis, Back Pain
- Trial name
- NCT00994032
- Testing
- percutaneous injection of cement into the vertebral body, Medical treatment
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Hospital Clinic of Barcelona
Osteoporosis
Impact of Vertebral Fracture Knowledge on Persistence in Subjects Taking Glucocorticoid Therapy
To evaluate the effect of subject knowledge of their disease status on persistence in subjects receiving Actonel 5 mg daily over a 12-month period for the prevention and treatment of GIO.
- Trial name
- ACTIVATE (NCT00616694)
- Testing
- Actonel
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Sanofi