Clinical trials: Fractures, Spinal
Degenerative Disc Disease, Trauma (Including Fractures)
BIO4 Clinical Case Study: Cervical Spine
The goal of this study is to investigate the efficacy of BIO4 bone matrix in patients undergoing 1 or 2-level Anterior Cervical Discectomy and Fusion (ACDF) spine surgery.
- Conditions
- Degenerative Disc Disease, Trauma (Including Fractures), Spondylolisthesis
- Trial name
- NCT03077204
- Testing
- 1 or 2-Level ACDF utilizing BIO4 with Bio AVS Cervical Allograft (with graft window)., Aviator Anterior Cervical Plating System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Seton Healthcare Family
SPINAL Fracture, Burst Fracture
Surgical Versus Non-Surgical Treatment of Thoracolumbar Burst Fracture
Treatment for acute traumatic thoracolumbar burst fractures differs significantly across the world in patients without neurological impairments and without damage to the posterior column of the spine.
- Conditions
- SPINAL Fracture, Burst Fracture, Spinal Instability of Thoracolumbar Region
- Trial name
- A34RCT (NCT05769114)
- Testing
- Surgical stabilization
- Where
- 2 sites in Switzerland
- Volunteers
- 52 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Post Operative Pain, Bradycardia
Comparison of EOSP Between Usg Guided S-FICB vs USG Guided PENG Block in Pts Undergoing Femur Fracture Surgery
To compare the immediate and postoperative analgesic efficacy of S-FICB and PENG block will be the objective. The use of ultrasonography in anesthesia has helped the anesthetist to see the nerve, needle and the distribution of…
- Conditions
- Post Operative Pain, Bradycardia, Hypotension, Femur Fracture
- Trial name
- NCT06568770
- Testing
- USG GUIDED SUPRA-INGUINAL FASCIA ILIACA BLOCK, PERICAPSULAR NERVE BLOCK
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Sahiwal medical college sahiwal
Vertebral Compression Fractures, Osteoporotic Vertebral Compression Fractures
A Controlled Trial of Vertebroplasty for Acute Painful Osteoporotic Fractures
The objective of this study is to gather data regarding the efficacy, safety and cost-effectiveness of percutaneous vertebroplasty in the acute fracture group with fractures less than 6 weeks old.
- Conditions
- Vertebral Compression Fractures, Osteoporotic Vertebral Compression Fractures, Acute Vertebral Fractures
- Trial name
- NCT01482793
- Testing
- Vertebroplasty
- Where
- Australia
- Volunteers
- 120 people
- Sponsor
- Optimus Clinical Research
Hip Fracture
Comparison of the Ultrasound Supra-inguinal Fascia Iliaca Block vs Femoral Nerve Block
Patients were randomly assigned to tow groups: infrainguinal ultrasound guided iliaca fascia block (FIBSI) and femoral nerve block (FNB) for FIBSI, the probe is placed transversely between anterior superior iliac spine (ASIS) and…
- Trial name
- NCT04692428
- Testing
- Locoregional analgesia
- Where
- Tunisia
- Volunteers
- 100 people
- Sponsor
- University Tunis El Manar
Spondylolisthesis, Neurologic Deficits
A Postmarket Surveillance Study of the Paradigm Spine Dynamic Stabilization System (DSS)
The purpose of the Post-Market Surveillance study is to evaluate safety.
- Conditions
- Spondylolisthesis, Neurologic Deficits, Kyphosis, Pseudarthrosis
- Trial name
- DSS (NCT01461005)
- Testing
- Dynamic Stabilization System (DSS)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Paradigm Spine
Depressed Lateral Condyle Fracture, Benign Bone Tumour Cavity
Bioactive Glass as Bone Graft Substitute in Operative Treatment of Bone - a 10 Years Follow-up Study
The main aim is to evaluate the long-term safety and bone healing in the operated area and to compare bioactive glass granules with autogenous bone as a filler material.
- Conditions
- Depressed Lateral Condyle Fracture, Benign Bone Tumour Cavity, Spinal Fusion
- Trial name
- NCT00935870
- Testing
- Bioactive glass and/or autogenous bone
- Where
- Finland
- Volunteers
- 63 people
- Sponsor
- Vivoxid Ltd
Healthy, Osteopenia
Clinical Study to Estimate Bone Mineral Density With the POROUS Ultrasound Device
Osteoporosis is a widespread medical condition among older people. It causes the bones to weaken and become more likely to break.
- Conditions
- Healthy, Osteopenia, Osteoporosis
- Trial name
- POROUS-BMD (NCT07187518)
- Testing
- Measurements with the POROUS R4C ultrasound device at the midshaft tibia, DXA measurement of the hip and lumbar spine
- Where
- 2 sites in Germany
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- POROUS GmbH
Lower Limb Fracture
Comparison of Postoperative Analgesia Between Intravenous Paracetamol and Intranasal Tapentadol
The aim of the study was to compare the analgesic efficacy of intranasal tapentadol nasal spray 44.5mg and intravenous paracetamol 1gm during the postoperative period by Visual analog scale(VAS)in patients undergoing lower…
- Trial name
- NCT05999890
- Testing
- Tapentadol Hydrochloride
- Where
- India
- Volunteers
- 74 people
- Sponsor
- Kempegowda Institute of Medical Sciences, Bangalore
Osteoporotic Vertebral Fracture, Between T5 and L5
Comparison of Balloon Kyphoplasty and Vertebroplasty in Subacute Osteoporotic Vertebral Fractures
This study aims to compare two treatments in subacute (more than 6 week duration) non-traumatic (usually osteoporotic) vertebral fractures. The two treatments are the following: 1.
- Conditions
- Osteoporotic Vertebral Fracture, Between T5 and L5, Chronic Arthritis, Longer Than Six Weeks Duration
- Trial name
- OSTEO+6 (NCT00749086)
- Testing
- balloon kyphoplasty, vertebroplasty
- Where
- France
- Volunteers
- 97 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spinal Cord Injury
S-100B and Neuron-specific Enolase (NSE) in Spinal Trauma
The investigators are studying the clinical worth of the serum markers S-100B and NSE in patients with spinal cord injuries e.g. in patients with vertebral fractures.
- Trial name
- WBS (NCT00980434)
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Cervical Radiculopathy, Cervical Spinal Fusion
FUSION EVALUATION AFTER ANTERIOR CERVICAL DISCECTOMY AND FUSION WITH STAND ALONE LOCKING CAGE WITH BLADE HRCC®
Cervical degenerative disease is an almost universal concomitant of human aging. Over half of the middle aged population has cervical spondylosis.
- Conditions
- Cervical Radiculopathy, Cervical Spinal Fusion, Cervical Myelopathy
- Trial name
- NCT03950349
- Where
- France
- Volunteers
- 50 people
- Sponsor
- CHU de Reims
Hip Fractures, Supra-inguinal Fascia Iliaca Block
Preoperative Supra-inguinal Fascia Iliaca Block for Positioning Analgesia in Hip Fracture Patients Undergoing Spinal Anesthesia
The goal of the clinical trial is to learn if preoperative Superficial Inguinal Fascia Iliaca (SIFI) block works to reduce pain during positioning for spinal anesthesia.
- Conditions
- Hip Fractures, Supra-inguinal Fascia Iliaca Block, Spinal Anesthesia
- Trial name
- NCT07556614
- Testing
- Isobaric bupivacaine 0.5%
- Where
- Pakistan
- Volunteers
- 132 people
- Sponsor
- Ghurki Trust and Teaching Hospital
Spinal Fusion, Lumbar Fusion
Lumbar Fusion With Porous Versus Non-Porous Cages
The objective of this single site, randomized controlled trial is to assess and compare radiographic and clinical outcomes in patients who are to undergo lumbar interbody fusion procedures (TLIF), supplemented with pedicle screw…
- Conditions
- Spinal Fusion, Lumbar Fusion, Arthrodesis, Spondylolisthesis
- Trial name
- NCT05583864
- Testing
- CONDUIT Porous Titanium Spinal Cage, PROTI 360 Titanium-Coated PEEK Spinal Cage
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Francis Farhadi
Kyphosis
Kyphotic Measure Using Distance From the Wall
Are the KypDisT and conventional C7WD are practical, valid, reliable, and effectiveness of the tools to discriminate the functional ability impairments relating to kyphosis when compare with gold standard (Cobb's method), and…
- Trial name
- NCT02914041
- Volunteers
- 96 people
- Sponsor
- Khon Kaen University
Spine Fracture, Orthosis
ORthosis vs No Orthosis After Surgically Treated Traumatic Thoracolumbar Fractures
Rationale: There is no evidence in the current literature regarding the additional value of an orthosis after surgically treated thoracolumbar spine fractures.
- Conditions
- Spine Fracture, Orthosis, Traumatic Fracture, Posterior Fixation
- Trial name
- ORNOT (NCT03097081)
- Testing
- No orthosis, Orthosis
- Where
- Netherlands
- Volunteers
- 45 people
- Sponsor
- Amsterdam UMC, location VUmc
Cuff Tear Arthropathy, Primary Osteoarthritis
Follow-up Evaluating Clinical and Radiological Outcomes of Total Shoulder Arthroplasty With Permedica's MIRAI Prosthesis
This observational study is conducted in order to evaluate the effectiveness of the primary total shoulder arthroplasty with the Permedica's MIRAI Modular Shoulder Prosthesis System on the general population of patients who are…
- Conditions
- Cuff Tear Arthropathy, Primary Osteoarthritis, Secondary Osteoarthritis, Shoulder Osteoarthritis
- Trial name
- NCT05128500
- Testing
- Total Shoulder Arthroplasty with Permedica's MIRAI
- Where
- 4 sites in Germany, Italy and 1 more
- Volunteers
- 76 people
- Sponsor
- Permedica spa
Low Back Pain, Stress Fracture
Treatment of Spondylolysisin Pediatric Patients.
A clinical trial comparing healing of unilateral or bilateral spondylolysis in children treated with a Boston thoracolumbar orthosis (brace) or with a soft spinal brace (Porostrap lumbar support) for four months.
- Trial name
- NCT03675152
- Testing
- Soft spinal brace, thoracolumbar orthosis, Excersice restriction
- Where
- 2 sites in Finland
- Volunteers
- 60 people
- Sponsor
- Turku University Hospital
Hip Fractures
MED90 of Ropivacaine for Peripheral Nerve Block on Posture-evoked Pain in Spinal Anesthesia Positioning
This study aims to determine the minimum effective dose of ropivacaine for peripheral nerve block on posture-evoked pain for spinal anesthesia in elderly patients with hip fracture.
- Trial name
- NCT04705974
- Testing
- Fascia iliaca block, Femoral nerve block, Pericapsular nerve group block (PENG block)
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Huazhong University of Science and Technology
Lumbar Vertebral Fracture
Percutaneous Screw Fixation vs. Open Fixation in the Treatment of Thoracolumbar Fractures
In this single-center retrospective study, the investigators will include all patients admitted to Parkland Hospital who underwent surgical fixation of thoracolumbar fractures between the years 2000 and 2017.
- Trial name
- PrecScrew (NCT04495400)
- Testing
- Thoracolumbar Fracture Fixation
- Where
- United States
- Volunteers
- 485 people
- Sponsor
- University of Texas Southwestern Medical Center