Clinical trials: Fractures, Spinal
Spine Fracture
Comparison Of Deep Versus Moderate Neuromuscular Blockade on Intra-Operative Blood Loss During Spinal Surgery
Reduction of intra-operative blood loss
- Trial name
- NCT05294926
- Testing
- Rocuronium, nerve stimulator
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Assiut University
Fracture of Lower Limb
Comparing Heavy Levobupivacaine With Enantiomeric Excess of 50% and Heavy Racemic Bupivacaine.
The purpose of this study is to compare the non-inferiority between Heavy Levobupivacaine with Enantiomeric Excess of 50% and Heavy Racemic Bupivacaine During Spinal Anesthesia for Orthopedic Procedures in the Lower Limbs.
- Trial name
- NCT01308047
- Testing
- Bupivacaine
- Where
- 2 sites in Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cristália Produtos Químicos Farmacêuticos Ltda.
Back Pain
To Evaluate Success of Cement Treatment of Spinal Compression Fractures
Patients with vertebral compression fracture will be treated cement injection into the spine and monitored using standard evaluations.
- Trial name
- NCT00166374
- Testing
- balloon kyphoplasty
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Chronic Renal Failure, Hip Fracture
Effects of Dexmedetomidine Premedication on Geriatric Patients With Chronic Renal Failure Undergoing Hip Surgery
Geriatric patients (age ≥ 65 years) undergo surgery for hip fractures that develops due to osteoporosis and falls. Dialysis-dependent chronic kidney disease is associated with an increased risk of cardiovascular comorbidity.
- Trial name
- NCT01837290
- Testing
- dexmedetomidine infusion for premedication, Midazolam, saline infusion
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Baskent University
Spinal Cord Injury, Osteoporosis
Early Intervention to Reduce Bone Loss After Spinal Cord Injury
After a complete spinal cord injury (SCI), the patient becomes wheelchair-dependent, and the associated lack of weight-bearing and inactivity of paralysed muscles can lead to extensive bone loss in the long bones of the legs.
- Trial name
- NCT02334410
- Testing
- Whole body vibration (WBV)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Strathclyde
Osteoporosis
Study of FORTEO Use in Subjects in the Community Setting
The purpose of this study is to evaluate the long-term effectiveness, safety, and tolerability of FORTEO in a larger, more diverse "real world" population than studied in clinical trials
- Trial name
- DANCE (NCT01078805)
- Testing
- FORTEO
- Where
- United States
- Volunteers
- 4,167 people
- Sponsor
- Eli Lilly and Company
Vertebral Body Compression
Efficacy of Kyphoplasty With a New Intervertebral Expander
Balloon kyphoplasty is a well-established treatment option to achieve pain relief and to correct kyphotic deformity caused by osteoporotic vertebral compression fracture.
- Trial name
- NCT03521661
- Testing
- Kyphoplasty
- Volunteers
- 41 people
- Sponsor
- Mohammad ARAB MOTLAGH
Spinal Fractures
PASS MIS® Post-market Clinical Follow-up
Prospective, multicenter non comparative and observational study (post-market clinical follow-up).
- Trial name
- NCT02931266
- Testing
- PASS MIS®
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Medicrea International
Osteoporotic Vertebral Fracture, Neuropathic Pain
Osteoporotic Fracture and Lidocaine Plaster 5% for Neuropathic Pain preventioN
Osteoporotic vertebral fractures may lead to chronic pain with a neuropathic component, which is often underdiagnosed and undertreated in older adults.
- Trial name
- FLYNN (NCT07691359)
- Testing
- Lidocaine 5% medicated plaster
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Necrosis of Femoral Head, Knee Osteoarthritis
Probiotics Attenuate Postoperative Cognition Decline
The aim of this study was to evaluate whether perioperative probiotics can reduce the incidence of postoperative cognitive dysfunction and postoperative delirium.
- Conditions
- Necrosis of Femoral Head, Knee Osteoarthritis, Fracture of Neck of Femur, Lumbar Disc Herniation
- Trial name
- NCT04017403
- Testing
- Bifidobacterium triple live capsule
- Where
- 3 sites in China
- Volunteers
- 220 people
- Sponsor
- RenJi Hospital
Osteoporotic Vertebral Compression Fractures
Continuous Mobility and Physical Activity in Vertebroplasty vs Sham for Osteoporotic Vertebral Fracture
The aim of this clinical trial is to determine if vertebroplasty is an effective treatment for acute, painful vertebral fractures due to osteoporosis.
- Trial name
- VOPE2 COMPAS (NCT06776003)
- Testing
- Vertebroplasty
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Spine Centre of Southern Denmark
Accidental Falls, Bone Fracture
Flooring for Injury Prevention Trial
This study will evaluate the efficacy of novel compliant flooring in reducing injuries due to falls in a long-term care facility, determine the cost effectiveness of this intervention, and assess perceptions about compliant…
- Conditions
- Accidental Falls, Bone Fracture, Traumatic Brain Injury, Head Injuries, Closed
- Trial name
- FLIP (NCT01618786)
- Testing
- SmartCell flooring, Plywood flooring
- Where
- Canada
- Volunteers
- 151 people
- Sponsor
- Dr. Stephen Robinovitch
Vertebral Fracture
Kyphoplasty With Structured Titanium Spheres
The aim of the trial is to study efficacy and safety of Kyphoplasty technique with porous titanium microspheres in patients with type A vertebral body fracture (according to Magerl classification).
- Trial name
- NCT04169659
- Testing
- Kyphoplasty with insertion of Sctructured Titanium Microspheres, Kyphoplasty with Polimethylmetacrilate (convetional surgery)
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- ARNAS Civico Di Cristina Benfratelli Hospital
One or Two Traumatic Vertebral Fractures, Located Between T11 and L5
Feasibility Study of Balloon Kyphoplasty in Traumatic Vertebral Fractures Needing Surgical Fixation
Some unstable traumatic vertebral fractures (types A3.2, A3.3, B1 et C1 according to MAGERL classification) may undergo unpredictable secondary displacement.
- Conditions
- One or Two Traumatic Vertebral Fractures, Located Between T11 and L5, Balloon Kyphoplasty
- Trial name
- TRAUMAA3B1C1 (NCT00749229)
- Testing
- balloon kyphoplasty
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spinal Anesthesia
Application of Unilateral Epidural Anesthesia in Older Patients With Hip Fracture
Because of population ageing, fragility fractures have become a huge burden on healthcare systems and wider society. Fractures result in a sharp drop in both short-term and long-term quality of life, they have a strong influence…
- Trial name
- NCT06093412
- Testing
- unilateral epidural anesthesia, combined lumbar and epidural anesthesia
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Sichuan Provincial People's Hospital
Spinal Anesthesia, Analgesia
Femoral Nerve Block vs Peri-capsular Nerve Group Block for Hip Fracture Analgesia
The purpose of the study is to compare the analgesic efficacy of femoral nerve block and peri-capsular nerve group block administered before spinal anesthesia for positioning to spinal anaesthesia in patients undergoing surgery…
- Conditions
- Spinal Anesthesia, Analgesia, Hip Fractures
- Trial name
- NCT05444803
- Testing
- femoral nerve block, peri-capsular nerve group block
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Antalya Training and Research Hospital
Vertebral Fracture, Osteoporotic Fractures
CCEF in the Treatment of Acute VFFs: Randomized Controlled Trial
in recent years the search for therapeutic protocols that could enhance the VFFs healing, thus reducing bed rest-related complications and improving the quality of life of osteoporotic patients.
- Trial name
- NCT05803681
- Testing
- Capacitive Coupled Electric Fields (CCEF), Calssic clinical protocol
- Volunteers
- 70 people
- Sponsor
- University of Bari Aldo Moro
Osteoporotic Fracture
Prevention of Residual Low Back Pain After Percutaneous Kyphosis(PKP) Using Posterior Branch Block of Spinal Nerve
The purpose of this study was to block the posterior branch of lumbar spinal nerve during PKP operation and compare it with the patients without spinal nerve block, so as to verify the effect of posterior branch block of spinal…
- Trial name
- NCT04108507
- Testing
- posterior branch block of spinal nerve
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Spinal Fractures
Uppsala Study on Odontoid Fracture Treatment in the Elderly
A multicenter randomized controlled trial is performed in Sweden (Uppsala, Malmo and Stockholm) comparing surgery with posterior C1-C2 fusion and conservative treatment with a rigid collar.
- Trial name
- USOFT (NCT02789774)
- Testing
- Posterior fusion C1-C2, Rigid cervical collar
- Where
- 2 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- Uppsala University
Spinal Fracture, Traumatic Fracture
Surgical Treatment of the Thoracolumbar Spine Fractures.
The thoracolumbar segment fractures are the most frequent along the spine, and surgical treatment is indicated in unstable fractures.
- Trial name
- NCT03316703
- Testing
- Conventional open surgery, Minimally invasive percutaneous surgery
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo