Clinical trials: Fractures, open to volunteers
Fracture Femur, Hip Arthroplasty Replacement
Cognitive and Physical Recovery After Hip Fracture in Frail Patients Using Digital Rehabilitation Technology
The aim of this study is to evaluate whether integrating a technology-based rehabilitation approach with conventional therapies in the rehabilitation of patients with proximal femoral fracture may be advantageous compared with…
- Conditions
- Fracture Femur, Hip Arthroplasty Replacement, Total Hip Arthroplasty (THA)
- Trial name
- FEWF (NCT07392515)
- Testing
- Experimental intervention - integrated treatment with a sensor-based device, Conventional rehabilitation intervention
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- C.O.T. Cure Ortopediche Traumatologiche S.p.A.
Trauma Centers, Trauma Patients
Assess the Efficacy of Tailored Patient Information and Voluntary Patient-managed Outpatient Digital Follow-up (I-POD) as an Adjunct to Standard Treatment According to National Guidelines in the National Trauma Plan Among Adult Trauma Patients in Norway.
The POSTRAUMA trial is a clinical trial at The Regional trauma centre of Western Norway, Haukeland University Hospital. Trauma is the leading cause of death worldwide in patients aged 1-45 years.
- Conditions
- Trauma Centers, Trauma Patients, Trauma (Including Fractures), Trauma Injury
- Trial name
- POSTRAUMA (NCT07268716)
- Testing
- The intervention is a tailored patient Information and Patient-managed Outpatient Digital follow-up treatment
- Where
- Norway
- Volunteers
- 256 people
- Sponsor
- Haukeland University Hospital
Rib Fractures
INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures
This is a prospective, randomized, non-blinded study comparing CINB plus medical therapy versus standard medical care (non-steroidals and opioids intravenous/oral inpatient and oral outpatient) alone for patients with multiple…
- Trial name
- NCT05642026
- Testing
- Ropivacaine, Non steroidal anti-inflammatory drug and opioids
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Zachary Warriner
Gingival Margin Elevation
Effect of Different Base Materials on Ginigiva During Gingival Margin Elevation
This study will be conducted to investigate 1. The effect of deep margin elevation with different base materials (resin modified glass ionomer, flowable composite, injectable hybrid composite) on fracture resistance and marginal…
- Trial name
- NCT06944080
- Testing
- base material(Tetric® N-Flow,Beautifil-Flow PLUS,GC fuji II LC capsule)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Minia University
Trauma (Including Fractures), Trauma Abdomen
5 Minute 'HOT' Trauma CT Rates Of Detection Study
Many injured patients receive urgent CT imaging to identify major injury. CT imaging of trauma patients is often time critical and the accurate detection of life-threatening findings on this CT is essential.
- Conditions
- Trauma (Including Fractures), Trauma Abdomen, Trauma Blunt, Trauma Centers
- Trial name
- NCT07314437
- Testing
- Education
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital Plymouth NHS Trust
Spine Fracture, Osteoporosis
Controlled Reduction of AO Spine B3 Fractures in Ankylosing Spinal Disorders Using an Inflatable Positioning Device: Technical Note and Retrospective Single-centre Case Series
Retrospective observational
- Conditions
- Spine Fracture, Osteoporosis, Spondylitis, Ankylosing
- Trial name
- NCT07847320
- Volunteers
- 23 people
- Sponsor
- Diakonie-Klinikum Stuttgart
Cervical Spine Fractures, Cervical Spine Injury
Study on Orthosis in Cervical Spine Fracture Treatment
Background and Purpose: Neck fractures affect over 1,100 people in Sweden each year, with the majority being frail older adults.
- Conditions
- Cervical Spine Fractures, Cervical Spine Injury, Rigid Collar
- Trial name
- SOFT (NCT06848660)
- Testing
- A rigid cervical collar
- Where
- 6 sites in Sweden
- Volunteers
- 616 people
- Sponsor
- Uppsala University Hospital
Femoral Neck Fractures
Comparison of the Direct Anterior Approach (DAA) and the Direct Lateral Approach (DLA) in Patients Treated With Partial Hip Replacement for Femoral Neck Fracture Based on Postoperative Functional Status
The goal of this clinical trial is to learn whether the surgical approach used for hemiarthroplasty can improve clinical and functional outcomes in adults with displaced femoral neck fractures.
- Trial name
- NCT07501741
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Hemorrhagic Shock, Pelvic Fractures
Hemorrhagic Shock in Orthopedic Fractures
The goal of this observational study is to learn about the incidence and predators of hemorrhagic shock in patients with Long bone and pelvic fractures .The main question it aims to answer is: In which bone fracture the…
- Conditions
- Hemorrhagic Shock, Pelvic Fractures, Long Bone Fractures
- Trial name
- NCT07695129
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Sohag University
Tibial Fracture
Tibial IMN Vs. Tibial Micromotion IMN
Our null hypothesis is that micromotion tibial intramedullary fixation (IMFN) does not impact union or complication rates when compared to standard of care treatment with non-micromotion tibial nail fixation.
- Trial name
- NCT06976801
- Testing
- Intramedullary tibial Nail, Intermedullary nail
- Where
- United States
- Volunteers
- 372 people
- Sponsor
- University of Chicago
Fracture of Neck of Femur
Orthopedic Intelligent Navigation System in the Treatment of Fresh Femoral Neck Fractures
The goal of this clinical trial is to verify the safety and effectiveness of orthopaedic surgical navigation system in the treatment of fresh femoral neck fractures.
- Trial name
- NCT06713018
- Testing
- Three cannulated compression screws by navigation system, Traditional three cannulated compression screws
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chinese PLA General Hospital
Fracture Distal Radius
Distal Radius Interventions for Fracture Treatment
This protocol describes a multicenter, prospective randomized superiority trial with a patient preference cohort comparing functional outcomes between children treated with sedated reduction versus no formal reduction.
- Trial name
- DRIFT (NCT05131685)
- Testing
- Reduction, Immobilization
- Where
- 24 sites in United States
- Volunteers
- 334 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Pain
Cannulated Bone Bolt® Screw System Versus Standard Cannulated Screw System Fixation for Pelvic Fractures
The investigators aim is to determine if the cannulated Bone Bolt® screw system will provide improved post-operative pain control as compared to standard cannulated screw system fixation for the operative treatment of LC1…
- Trial name
- NCT07209280
- Testing
- Cannulated Bone Bolt® Screw System, Standard Cannulated Screw System
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Distal Femur Fracture
Distal Femur Fx: ORIF(Open Reduction and Internal Fixation) vs DFR (Distal Femur Replacement Total Knee Arthroplasty)
Supracondylar femur periprosthetic fractures about a total knee arthroplasty (TKA) are a catastrophic and challenging complication of TKA and unfortunately are increasing in incidence.
- Trial name
- NCT05792189
- Testing
- Timed Up and Go Test on subjects with ORIF of distal femur fractures, Koos Jr assesment on subjects with ORIF of distal femur fractures, Timed Up and Go Test on subjects with DFR of distal femur fracture
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Florida
Humeral Shaft Fracture
Unipolar Versus Bipolar Interlocking in Humeral Shaft Fractures in Adults
Shaft fractures account for 20% of humeral fractures and 3% of all adult fractures in France, with an estimated incidence of 13 to 20/100,000 people.
- Trial name
- UNILOCH (NCT05877014)
- Testing
- questionnaires, scanner
- Where
- France
- Volunteers
- 390 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Osteoporotic Fractures, Vertebral Fracture
Percutaneous Vertebroplasty Vs. Sham for Osteoporotic Vertebral Compression Fractures Focusing on Pain and Economy.
The purpose of this randomized double-blind clinical trial is to determine the efficacy of percutaneous vertebroplasty (PVP) in relieving severe pain in patients with MRI-verified acute or sub-acute osteoporotic vertebral…
- Trial name
- VOPE2 (NCT06141187)
- Testing
- Vertebroplasty
- Where
- Denmark
- Volunteers
- 240 people
- Sponsor
- Spine Centre of Southern Denmark
Arthritis, Femoroacetabular Impingement
Conjoint Analysis of Patient Preferences in Joint Interventions
This study is an observational study to test and validate a questionnaire and statistical model used to determine patient preferences regarding treatment for any one of 11 musculoskeletal conditions: hip arthritis, knee…
- Conditions
- Arthritis, Femoroacetabular Impingement, Osteochondritis Dissecans, Hip Fractures
- Trial name
- NCT02664337
- Testing
- Decision tool, Standard treatment information
- Where
- United States
- Volunteers
- 2,310 people
- Sponsor
- Duke University
Alcohol Use Disorder, Stress Reaction
Neurobehavioral Profiles of Adaptive Stress Responses in Individuals With Alcohol Use Disorder
The goal of this observational study is to investigate longitudinal stress response profiles and adaptive versus non-adaptive stress responses in alcohol use disorder.
- Conditions
- Alcohol Use Disorder, Stress Reaction, Social Stress, Craving
- Trial name
- A03 (NCT06105853)
- Testing
- Trier Social Stress Test, Barlab Cue-Exposure, Functional magnetic resonance imaging
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Next Generation Sequencing (NGS), Surgical Site Infection (SSI)
Efficacy of Integrating Next Generation Sequencing for Treatment of Surgical Site Infection After Fracture Fixation:
The study focuses on the serious problem of infections and wound-healing issues that can happen after high-energy bone fractures.
- Conditions
- Next Generation Sequencing (NGS), Surgical Site Infection (SSI), Fracture Fixation
- Trial name
- NGS (NCT07458230)
- Testing
- NGS diagnostic findings
- Where
- 18 sites in United States
- Volunteers
- 250 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Stress Response
Effect of Nebulized Lignocaine on the Stress Response of Endotracheal Intubation in Pediatrics Undergoing Tonsillectomy Operation Monitored by Rise in Serum Cortisol Level Post Intubation
This randomized clinical trial aims to is examining the effect of preoperative nebulized lidocaine on the stress response to intubation, monitored by rise in serum cortisol level post intubation
- Trial name
- NCT07139730
- Testing
- Lignocaine 2% concentration solution
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University