Clinical trials: Fragmentation, Sleep
Pain, Healthy
Fragmented Sleep, Pain, and Biomechanics
This interventional study aims to test the effects of sleep disruption on pain sensitivity and biomechanics in healthy individuals during experimental knee and shoulder pain.
- Conditions
- Pain, Healthy, Sleep Disturbance
- Trial name
- NCT06336109
- Testing
- Hypertonic saline knee and shoulder injection
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Obstructive Sleep Apnea
Inspiratory Muscle Strength Training for Sleep-related Breathing Disorders
The purpose of the current study is to investigate the effects of a novel breathing training, called inspiratory muscle strength training (IMST), on sleep patterns, breathing and blood pressure for patients diagnosed with mild…
- Trial name
- NCT02709941
- Testing
- Inspiratory muscle strength training
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Arizona
Menopause
Menopausal Sleep Fragmentation and Body Fat Gain
This study aims to investigate the impact of menopause-related sleep fragmentation on metabolic biomarkers of body fat gain. The investigators hypothesize that experimental sleep fragmentation will result in an adverse leptin…
- Trial name
- NCT03047330
- Testing
- Estradiol withdrawal, Fragmented sleep
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
COVID-19, Healthy Volunteers
Executive Functioning and Sleep Fragmentation in COVID-19 Patients
This project aims to investigate executive functioning abilities (primary outcome) and quality of sleep (secondary outcome) in patients with COVID-19 (while distinguishing between those with and without sleep fragmentation)…
- Trial name
- NCT05764096
- Testing
- No intervention
- Where
- Italy
- Volunteers
- 76 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Chronic Respiratory Failure
Adaptation to Nocturnal Noninvasive Ventilation in Patients With Chronic Respiratory Failure (ROOMILA)
BACKGROUND: Adaptation to noninvasive ventilation (NIV) is a critical step for acceptability and efficacy of this treatment during sleep in patients with chronic respiratory failure.
- Trial name
- ROOMILA (NCT01255111)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Groupe de Recherche sur le Handicap Respiratoire
Alzheimer's Disease, Obstructive Sleep Apnea
Role of Hypoxia Ans Sleep Fragmentation in Alzheimer's Disease. and Sleep Fragmentation.
Alzheimer's Disease (AD) is the most prevalent neurodegenerative disease, manifested as an initial deficit of episodic memory that evolves into a global cognitive and psychosocial dysfunction and which prevalence is increasing…
- Trial name
- NCT02814045
- Where
- 2 sites in Spain
- Volunteers
- 144 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Sleep Apnea Syndromes, Sleep Initiation and Maintenance Disorders
Sleep Deficiency and Stroke Outcome
Deficient sleep duration and sleep disturbances - such as insomnia, sleep disordered breathing (SDB) and restless legs syndrome (RLS)- are associated with hypertension and cardio-cerebrovascular morbidity and mortality.
- Conditions
- Sleep Apnea Syndromes, Sleep Initiation and Maintenance Disorders, Insomnia, Restless Legs Syndrome
- Trial name
- NCT02559739
- Where
- 2 sites in Switzerland
- Volunteers
- 447 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
White Noise, Sleep
Sleepless at Scripps: An Inpatient White Noise Study
Sleep is an important part of the healing process, and patients admitted to the hospital often report poor sleep. Patients have difficulty not only falling sleep, but also staying asleep.
- Conditions
- White Noise, Sleep, Sleep Fragmentation, Sleep Duration
- Trial name
- NCT05475262
- Testing
- Active white noise, Inactive white noise
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Scripps Health
Circadian Dysregulation, Sleep Fragmentation
Compromised Sleep and Circadian Health After Critical Illness: From Diagnosis to Prediction (CHRONOCRIT)
The intensive care unit (ICU) is recognizably detrimental to sleep and circadian health, and critical survivors frequently report the presence of alterations in this regard after hospital discharge.
- Trial name
- CHRONOCRIT (NCT05995132)
- Where
- Spain
- Volunteers
- 271 people
- Sponsor
- Institut de Recerca Biomèdica de Lleida
Sleep Fragmentation, Behavioural and Psychiatric Symptoms of Dementia
Therapy Light Rooms for Improved Sleep in Dementia Patients
This intervention study will investigate the effect of therapy light rooms on sleep, circadian rhythms, mood, behavioural problems and function in nursing home (NH) patients with dementia.
- Conditions
- Sleep Fragmentation, Behavioural and Psychiatric Symptoms of Dementia, Dementia
- Trial name
- DEMLIGHT (NCT03357328)
- Testing
- Therapy light room, Standard light
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- University of Bergen
Parkinson's Disease, Sleep Fragmentation
Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease (Aim 2)
Parkinson's Disease (PD) is the second most common of the age-related neurodegenerative disorders, affecting over 1,900 adults per 100,000 over the age of 80 in the US.
- Trial name
- NCT05070013
- Testing
- Deep Brain Stimulation
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Nebraska
Sleep Disorder, Healthy
Effects of Experimental Sleep Disturbances on Receptor Function of Study Drug
The overall goal of this project is to determine whether common sleep disturbance patterns, sleep continuity disturbance (SCD) and Sleep Fragmentation (SF), alter cerebral study drug receptor availability, drug-based analgesia…
- Trial name
- Sleep-MOR (NCT04299490)
- Testing
- Sleep Fragmentation, Sleep Continuity Disruption, Undisturbed Sleep
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Chronic Obstructive Pulmonary Disease
Effects of an Air Purifying Device (PureNight) on Sleep Quality in Obstructive Lung Disease
Many individuals with chronic lung disease have night time symptoms that disrupt their sleep. The purpose of this study is to determine the effects of an air purifying device (PureNight, Halo Innovations, Minneapolis, MN) on…
- Trial name
- NCT01772342
- Testing
- HEPA filtration
- Volunteers
- 50 people
- Sponsor
- VA New York Harbor Healthcare System
Sleep Deprivation, Sleep Fragmentation
Understanding Sleep in Hospitalized Older Patients
The overall goal of this research is to elucidate how environmental, healthcare, and patient-level factors and patients' level of perceived control impact sleep duration and quality in hospitalized older patients and to assess…
- Trial name
- NCT01057823
- Where
- United States
- Volunteers
- 771 people
- Sponsor
- University of Chicago
Sleep, Mild Cognitive Impairment
Light and Sleep Fragmentation
This trial will examine scheduled exposure to bright light in the morning and afternoon as a countermeasure to sleep fragmentation in older individuals with mild cognitive impairment.
- Conditions
- Sleep, Mild Cognitive Impairment, Mood Disorders
- Trial name
- NCT06009289
- Testing
- Light therapy
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Stanford University
Sleep Fragmentation, Poor Quality Sleep
Impact of Behavioral Treatment of Insomnia on Nighttime Urine Production
Nocturia is prevalent in older adults and it vastly reduces quality of life. Yet its treatment remains inadequate because its causes are not well understood, especially nocturnal polyuria or increased urine production at night.
- Conditions
- Sleep Fragmentation, Poor Quality Sleep, Nocturia, Nocturnal Enuresis
- Trial name
- NCT03883724
- Testing
- Brief behavioral treatment of insomnia (BBTI), Information-only control (IC)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh