Clinical trials: Frail
Physical Activity
Training Intervention in Heart Failure and Frail Elderly Population
There is enough scientific evidence of the benefits detection of frailty in patients with heart failure, which is an important prognostic factor.
- Trial name
- TIHFEP (NCT02365155)
- Testing
- Multicomponent training intervention., Nutrition intervention, Cognitive intervention
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Hospital de la Ribera
Frail Elderly Syndrome
Frailty Assessment and Treatment Strategies in the Elderly at Risk of Functional Decline in the Community
This study aims to design a patient -centered program to prevent or delay frailty , functional decline and adverse events, and evaluates the effectiveness of the program with a randomized clinical trial.
- Trial name
- NCT03591055
- Testing
- CGA, medication review, exercise and cognitive stimulation
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Frailty, Frail Elderly Syndrome
Frailty Assessment in Vascular Hot Clinic Setting - Feasibility and Prognostic Value
A single-centre prospective study of feasibility assessing the suitability of introducing routine frailty screening in a controlled, and reproducible, outpatient department setting for Vascular Surgery patients.
- Conditions
- Frailty, Frail Elderly Syndrome, Surgery
- Trial name
- FAVOUR (NCT06040658)
- Testing
- Frailty assessment
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Hypertension, Dementia
BedMed-Frail: Does the Potential Benefit of Bedtime Antihypertensive Prescribing Extend to Frail Populations?
High blood pressure (present in 1 of 5 Canadian adults) increases the risk of heart attack and stroke. Blood pressure lowering pills reduce this risk - but perhaps not optimally.
- Trial name
- NCT04054648
- Testing
- Bedtime administration of the participant's pre-existing antihypertensive medications
- Where
- Canada
- Volunteers
- 776 people
- Sponsor
- University of Alberta
Elderly
Activity Monitoring in Frail Elderly Patients
The purpose of this stuydy is to assess the bias and repeatability of the DynaPort MicroMod in measuring movement / physical activity in frail elderly.
- Trial name
- NCT02089516
- Where
- 2 sites in Netherlands
- Volunteers
- 18 people
- Sponsor
- Medical Research Foundation, The Netherlands
Intelligent Video Surveillance, Fall
Superiority of Intelligent Video Surveillance + Telealarm Over Telealarm Alone in Elderly People at Risk of Falling
Maintaining the elderly at home and preventing them from falling are major public health issues. The vast majority of elderly people wish to remain at home.
- Conditions
- Intelligent Video Surveillance, Fall, Home, Frail Elderly Person
- Trial name
- VIGIALARM (NCT05875038)
- Testing
- video system, Tele-alarm
- Where
- France
- Volunteers
- 395 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Osteopenia, Sarcopenia
Effect of Electromyostimulation on Bone
Although there is some evidence that whole body electromyostimulation(WB-EMS) affect bone via its acute and longitudinal effects on muscle mass and strength, the corresponding impact on bone density and falls in older adults has…
- Conditions
- Osteopenia, Sarcopenia, Falls
- Trial name
- NCT01296776
- Testing
- wellness control group., whole-body electromyostimulation
- Where
- Germany
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Elderly, Frail
Improving Balance in Frail Elderly
The objective of this pilot study is to estimate, for a frail elderly population, the extent to which balance improves following a Core-Strength training program in comparison to a Stretch \& Strength program.
- Trial name
- NCT00785746
- Testing
- Core
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McGill University
Frail Elderly Syndrome, Frailty
Keeping Active in Residential Elderly
This trial will take the form of a feasibility study; designed to assess the feasibility of a proposed future clinical trial in this setting.
- Conditions
- Frail Elderly Syndrome, Frailty, Physical Activity
- Trial name
- KARE (NCT03141879)
- Testing
- HUR equipment resistance training intervention
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University of Birmingham
Frail Elderly Syndrome
No Association Between Vitamin C and E Supplementation, Frailty, and Grip Strength Over Five Years: The CoLaus Study
To assess the cross-sectional and 5-year prospective association between self-reported vitamin C+E dietary supplementation and markers of grip strength and frailty in community-dwelling Swiss adults.
- Trial name
- CoLaus (NCT03258970)
- Testing
- Observational cohort study
- Where
- Switzerland
- Volunteers
- 2,711 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Frail Elderly Syndrome
GrandMove Project to Promote Elders' Robustness Against Frailty
This is a single-blind, cluster randomized, cross-over trial to investigate the effectiveness of (1) a 6-month aerobic exercise program, (2) a 6-month resistance exercise program, versus (3) a 6-month psychoeducation program on…
- Trial name
- GrandMove (NCT05397288)
- Testing
- Resistance exercise (R), Aerobic exercise (A), Healthy lifestyle education (E)
- Where
- Hong Kong
- Volunteers
- 390 people
- Sponsor
- The University of Hong Kong
Anesthesia, General, Aged, 70 and Over
Frail Status of Elderly Patients After Repair and Anesthesia Guided by the bispectraL Index
The first aim of this study is to compare two methods of administration of intravenous anesthetics to obtain the same level of depth (bispectral index between 40 and 60): manual or automated and to determine a mid-term (6 months)…
- Trial name
- FRAGIL (NCT02524327)
- Testing
- Toolbox: Automated group, Manual group
- Where
- 4 sites in France
- Volunteers
- 134 people
- Sponsor
- Hopital Foch
Atrial Fibrillation
Efficacy and Safety of Apixaban in Korean Frail Atrial Fibrillation Patient
Atrial fibrillation (AF) is the most common arrhythmia, and its prevalence is increasing with the aging population [1]. As the prevalence of AF is significantly rising among the population over 70-80 years old and considering the…
- Trial name
- NCT05773222
- Testing
- Apixaban
- Where
- South Korea
- Volunteers
- 2,002 people
- Sponsor
- Seoul National University Hospital
Frailty, Older People
Sense of Control in Frail Older Persons
The proposed study seeks to explore the lived experience of control and wellbeing of older people diagnosed with frailty within the care service provision in southern England.
- Conditions
- Frailty, Older People, Sense of Control
- Trial name
- CONtrol (NCT04503811)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Bournemouth University
Frail Elderly
High Intensity Interval Training Versus Moderate Intensity Continuous Training in Frail Elderly
The assessment and systematic integration of physical activity into the care pathway of frail elderly people is essential to prevent loss of independence and improve the quality of life of this population.
- Trial name
- EPAF (NCT07211334)
- Testing
- Exercise Training
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Grenoble
Falls, Frailty
VIVI-OLIVE: Multicomponent Exercise and Extra Virgin Olive Oil in Older Adults at High Risk of Falls
VIVI-OLIVE is a multicenter randomized clinical trial evaluating whether a 24-month intervention combining an individualized multicomponent exercise program (VIVIFRAIL), Mediterranean diet counselling, and supplementation with 60…
- Trial name
- VIVI-OLIVE (NCT07829484)
- Testing
- VIVIFRAIL multicomponent exercise program, Mediterranean diet counselling, Extra virgin olive oil supplementation
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Fundacion Miguel Servet
Frail Elderly Syndrome, Heart Failure
Medical Monitoring of Older Adults Patients After Discharged From Heart Failure Hospitalization
Introduction: PRESAGE CARE has developed a solution for early detection of the risk of emergency department visits and unscheduled hospitalizations.
- Trial name
- NCT06018532
- Testing
- PRESAGE CARE
- Volunteers
- 100 people
- Sponsor
- Presage
Residents in Longterm Care Facilities
Better tArgetting, Better Outcomes for Frail ELderly Patients
The acronym for this proposal, BABEL, refers to the fact that a common "language" - the interRAI risk-stratification and decision-making tool - will be used in this project, allowing several measures of care quality in long-term…
- Trial name
- BABEL (NCT06034444)
- Testing
- interRAI LTCF
- Where
- Canada
- Volunteers
- 5,692 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Accidental Falls
Effect on Falls Reduction of a Multimodal Intervention in Frail and Pre-frail Elderly Community-dwelling People
Practice guidelines in caring for the geriatric population recommend performing an annual screening of falls . However, one of the problems that interfere with fall prevention programs is the lack of importance accorded to health…
- Trial name
- FAREMAVA (NCT02631330)
- Testing
- Multicomponent physical activity
- Where
- Spain
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- Hospital de la Ribera
Frail Elderly, Inpatients
Grip Strength Routine Implementation (GRImP)
Hand grip strength (GS) is a non-invasive marker of whole body skeletal muscle strength and function used in research and recommended as a simple inexpensive measure suitable for clinical use.
- Trial name
- NCT02447445
- Testing
- Grip strength assessment
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust