Clinical trials: Frail
Frail Older Adults
Effectiveness of a Comprehensive Patient-centered Hospital Discharge Planning Intervention for Frail Older Adults
A large number of frail older adults have difficulty performing activities of daily living and resuming former roles in the months following hospital discharge.
- Trial name
- HOME (NCT04154917)
- Testing
- HOME
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Université de Sherbrooke
Dental Prosthesis Failure, Frail Elderly Syndrome
Immediate Dental Prosthesis Functionalization Protocol in People Over 70 Years of Age
Sarcopenia and malnutrition are closely involved in frailty. To prevent them, it is essential to assess oral function. "Oral fragility" manifests with specific signs or symptoms, including occlusion loss due to tooth loss and…
- Trial name
- NCT05818436
- Testing
- Procedure: prosthetic functioning, Conventional dental prosthesis
- Where
- Chile
- Volunteers
- 124 people
- Sponsor
- University of Chile
Elderly, Frail, Accidental Falls
Reconfiguring the Patient Room to Increase Patient Stability
Despite decades of research into patient falls, falls and the injuries incurred continue to be a serious threat to patient safety. Fall rates continue to be unacceptably high.
- Conditions
- Elderly, Frail, Accidental Falls, Hospitals
- Trial name
- NCT04003779
- Testing
- Room configuration
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Utah
Frail Elderly, Coronary Artery Disease
Off-pump Versus On-pump Coronary Artery Bypass Grafting in Frail Patients
Frailty is defined as a geriatric syndrome of impaired resiliency to stressors (such as cardiac surgery) that has been delineated recently in the cardiovascular literature.
- Trial name
- FRAGILE (NCT02338947)
- Testing
- Off-pump coronary-artery bypass grafting, On-pump coronary-artery bypass grafting
- Where
- 7 sites in United States, Brazil
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Frail Elderly
Effect of Modified Poco-Poco Exercise to Frailty Stages, Expression of Global DNA Methylation, GDF15 and Lamin A COP
The goal of this clinical trial is to know the effect of multicomponent exercise in frail elderly in community to aging hallmarks. The main question[s] it aims to answer are: 1.
- Trial name
- NCT06628895
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION
- Where
- Indonesia
- Volunteers
- 17 people
- Sponsor
- Universitas Padjadjaran
Frailty, Frail Elderly
Prehabilitation of Elderly Patients With Frailty Syndrome Before Elective Surgery (PRAEP-GO)
The aim of the study is to evaluate the effect of a shared decision-making conference and three-week prehabilitation program on the outcome "care dependency" one year after surgery.
- Trial name
- NCT04418271
- Testing
- Prehabilitation- new form of care
- Where
- 23 sites in Germany
- Volunteers
- 1,199 people
- Sponsor
- Charite University, Berlin, Germany
Frailty, Frail Elderly Syndrome
The NADage Study: Nicotinamide Riboside Replenishment Therapy Against Functional Decline in Aging
This clinical study, designed as a double-blind, randomized, placebo-controlled trial, aims to investigate the potential of nicotinamide riboside (NR) to decelerate functional decline in the elderly frail population.
- Conditions
- Frailty, Frail Elderly Syndrome, Frailty Syndrome, Aging
- Trial name
- NADage (NCT06208527)
- Testing
- Nicotinamide Riboside (NR)
- Where
- 2 sites in Norway
- Volunteers
- 100 people
- Sponsor
- Haukeland University Hospital
Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment (MCI)
CPAP Randomized Controlled Trial
The overall goal of this randomized controlled trial is to test the hypothesis that in older adults with mild cognitive impairment (MCI) and previously untreated obstructive sleep apnea (OSA), 4 months of web-based sleep…
- Conditions
- Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment (MCI), Cognitive Decline Prevention in Pre-frail Older Adults
- Trial name
- NCT06773416
- Testing
- CPAP Therapy Combined with Web-Based Sleep Education for Cognitive and Sleep Health, Delayed CPAP Therapy Combined with Web-Based Sleep Education for Cognitive and Sleep Health
- Where
- Canada
- Volunteers
- 206 people
- Sponsor
- Sunnybrook Health Sciences Centre
Pre-frail Elderly
Effects of Combined Motor and Cognitive Training in Pre-frail Elderly
The objective of this study is to investigate psychometric properties of dual-task walking assessments and compare effects of combined motor and cognitive training on physical fitness, brain fitness, and dual-task walking…
- Trial name
- NCT04605809
- Testing
- combined motor and cognitive training, motor training alone, cognitive training alone
- Where
- Taiwan
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Stomach Neoplasms, Frail Elderly
Multimodal Prehabilitation To Improve The Clinical Outcomes Of Frail Elderly Patients With Gastric Cancer
The GISSG+2201 study was launched by Shandong Gastrointestinal Surgery Study Group (GISSG). The intention is to establish a multimodal prehabilitation protocol in frail elderly patients who undergo gastric cancer radical surgery…
- Trial name
- NCT05352802
- Testing
- Multimodal prehabilitation program, ERAS protocol
- Where
- China
- Volunteers
- 368 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Frailty Syndrome, Pre-frail Older Adults
Targeted Physical Function Exercises on Frailty and Falls Management in Pre-Frail Community-Dwelling Older Adults
The investigators will conduct a randomized controlled trial to assess the impact of targeted physical function exercises on frailty and falls in community-dwelling adults over 65 years of age.
- Trial name
- NCT06731712
- Testing
- Physical Function Exercises
- Where
- Greece
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Hellenic Mediterranean University
Frail Elderly Syndrome, Older Adults
A Digital Home-Based Physiotherapy Program for Active Aging
This clinical trial will aim to understand the effects of the TRAK-SILVER digital platform on pre-frail and older adults living at home, assessing its impact on physical activity level, emotional variables, and overall quality of…
- Trial name
- TRAK-SILVER (NCT06381336)
- Testing
- TRAK-SILVER platform
- Where
- Spain
- Volunteers
- 72 people
- Sponsor
- Trak Health Solutions S.L.
Frail Elderly
Prevalence of Malnutrition and Frailty Among the Urban Community Elderly in Bandung
The goal of this observational study is to learn prevalence of malnutrition and frailty in elderly in Community in Bandung. The main question it aims to answer: what is the prevalence of malnutrition and frailty in elderly in…
- Trial name
- NCT06701045
- Where
- Indonesia
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Frail Elderly
Video Decision Support for Advance Care Planning in Geriatric Patients With Frailty
As the proportion of the aging population continues to rise, age-related frailty syndrome, characterized by a decline in the function of multiple physiological systems and accompanied by vulnerability to stress, has become a…
- Trial name
- NCT06671353
- Testing
- video decision aid
- Where
- Taiwan
- Volunteers
- 96 people
- Sponsor
- National Taiwan University Hospital
Fall Prevention, Autonomy of Older People
Advanced Practice Nurses for Fall Incidence PrevenTion in Very Old Robust Adults
APN-FIT is a hybrid type 1 clinical trial comparing the effect of an APN delivered fall prevention programme with standard care in non-frail patients.
- Conditions
- Fall Prevention, Autonomy of Older People, Frail Elderly, Advanced Practice Nursing
- Trial name
- APN-FIT (NCT06617806)
- Testing
- Follow-up by the Advanced Practice Nurse
- Where
- France
- Volunteers
- 386 people
- Sponsor
- Nantes University Hospital
Thoracic, Thoracic Neoplasm
A Prospective Study Frailty for Esophagectomy and Lung Resection in Thoracic Surgery
The purpose of this study is to develop an all-encompassing frailty model using laboratory and functional studies. A frailty model will help us determine prior to surgery who will require rehabilitation and skilled nursing needs…
- Conditions
- Thoracic, Thoracic Neoplasm, Lung Cancer, Esophageal Cancer
- Trial name
- NCT03413449
- Testing
- Frailty model
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- The Cleveland Clinic
Exergaming, Frail Elderly
Home-Based Exergame Program for Community-Dwelling Older Adults
The purpose of this study was to investigate the effect of a home-based exergame program on physical function, fall efficacy, depression, and quality of life in older adults.
- Trial name
- NCT05802537
- Testing
- Home-based exergame program, Online education on fall prevention and musculoskeletal health management
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kyungdong University
Frail Elderly
Effects of Remote Exercise on Physical Function in Pre-Frail Older Adults
This study aims to compare the effects of remote versus in-person exercise interventions on physical function, balance, gait stability, and fall efficacy in pre-frail older adults aged 65 years and above.
- Trial name
- NCT06672640
- Testing
- Remote Exercise Program, In-Person Exercise Program, Physical Activity Education
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Kyungdong University
Frail Elderly Syndrome, Major Surgery
Multimodal Prehabilitation for Surgery in the Elderly: a Randomised, Prospective, Multicenter, Multidisciplinary Trial
This multicentric, randomised controlled trial is to the investigators knowledge the first implementation of a multimodal, multidisciplinary prehabilitation approach using knowledge from different specialties to lower…
- Trial name
- PREHABIL (NCT04461301)
- Testing
- Multimodal Prehabilitation
- Where
- Switzerland
- Volunteers
- 466 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Frailty, Surgery--Complications
Protocol for Patients Above 75 Years Undergoing Emergency Laparotomy
In the ProPEL study the effect of a protocol designed for elderly patients about to undergo emergency abdominal surgery will be investigated. The protocol addresses issues of both frailty and ceiling-of -care decisions.
- Conditions
- Frailty, Surgery--Complications, Outcome, Fatal, Frail Elderly Syndrome
- Trial name
- (ProPEL) (NCT04293653)
- Testing
- Protocol for patients above 75 undergoing emergency laparotomy or laparoscopy
- Where
- Norway
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital