Clinical trials: Frail Elderly Syndrome
Frail Elderly Syndrome
Multifactorial Fall Prevention Program
The main objective is evaluate the effectiveness of a Multifactorial Pilot Program on the Prevention of Falls in people aged 65 or over during 4 years at Gerencia de Atención Integrada de Talavera de la Reina.
- Trial name
- Dodgers (NCT05682872)
- Testing
- Physical exercise program (VIVIFRAIL) supervised by a physiotherapist, Adequacy of the environment, Polypharmacy review
- Where
- Spain
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Castilla-La Mancha Health Service
Frail Elderly Syndrome
Protocol of Geriatric Rehabilitation in Patients of 60 and Older Who Live in Moscow Boarding Houses or Nursing Homes
After screening complex geriatric assessment (CGA) the participants will undergo geriatric rehabilitation programs. After termination of 21-day program, CGA will be repeated and subjects will get a program of long-term…
- Trial name
- POSTSCRIPTUM (NCT05740436)
- Testing
- Geriatric rehabilitation program based on CGA
- Where
- Russia
- Volunteers
- 420 people
- Sponsor
- Pirogov Russian National Research Medical University
Frail Elderly Syndrome, Primary Prevention
Non-pharmacological Prevention of POD in Frailty Elderly Undergoing Elective Surgery Applied by Nursing Teams
The increase in the population over 60 years of age who could receive surgery due to changes in life expectancy and advances in surgical and anesthetic techniques.
- Conditions
- Frail Elderly Syndrome, Primary Prevention, Postoperative Delirium, Frailty
- Trial name
- NPPOD (NCT05993754)
- Testing
- Non-pharmacological intervention
- Where
- Chile
- Volunteers
- 400 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Frailty in Adult Surgery, Frail Elderly Syndrome
Patient's Database: Prepare for Your Surgery Program
Frailty is a multidimensional syndrome that predominantly affects older people and people with long-term treatments such as cancer and chronic pain.
- Conditions
- Frailty in Adult Surgery, Frail Elderly Syndrome, Database, Perioperative Care
- Trial name
- NCT06857981
- Testing
- Clinical data collection
- Where
- 2 sites in Chile
- Volunteers
- 120 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Frail Elderly Syndrome
Protocols and Guidelines for the Use of Digital Twins in Frail Older People
The Proto-Aging study aims to define experimental protocols and guidelines to enable the development of musculoskeletal models (digital twins) of elderly people, with the ultimate goal to comprehensively characterize frail elders…
- Trial name
- Proto-Aging (NCT05854316)
- Testing
- Comprehensive Biomechanical assessment
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Transplant-Related Disorder, Frail Elderly Syndrome
Improving Frailty With a Rigorous Ambulation Intervention in Lung Transplant Patients
The objective of this study is to assess the feasibility and effectiveness of dedicated ambulator-assisted physical activity in lung transplant inpatients.
- Conditions
- Transplant-Related Disorder, Frail Elderly Syndrome, Sarcopenia, Lung Graft Dysfunction
- Trial name
- iFRAIL (NCT03636412)
- Testing
- Ambulation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The Cleveland Clinic
Frail Elderly Syndrome, Frailty
Frailty Assessment by Edmonton Frail Scale to Predict Outcome in Patients Undergoing Cardiovascular Surgery
The aim of the study is to assess frailty of patients admited for cardio-vascular surgery in Cliniques Universitaires Saint Luc in Brussels.
- Conditions
- Frail Elderly Syndrome, Frailty, Surgery
- Trial name
- FRAIL-HEART (NCT03913299)
- Where
- 3 sites in Belgium
- Volunteers
- 2,080 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Dental Prosthesis Failure, Frail Elderly Syndrome
Immediate Dental Prosthesis Functionalization Protocol in People Over 70 Years of Age
Sarcopenia and malnutrition are closely involved in frailty. To prevent them, it is essential to assess oral function. "Oral fragility" manifests with specific signs or symptoms, including occlusion loss due to tooth loss and…
- Trial name
- NCT05818436
- Testing
- Procedure: prosthetic functioning, Conventional dental prosthesis
- Where
- Chile
- Volunteers
- 124 people
- Sponsor
- University of Chile
Frailty, Frail Elderly Syndrome
The NADage Study: Nicotinamide Riboside Replenishment Therapy Against Functional Decline in Aging
This clinical study, designed as a double-blind, randomized, placebo-controlled trial, aims to investigate the potential of nicotinamide riboside (NR) to decelerate functional decline in the elderly frail population.
- Conditions
- Frailty, Frail Elderly Syndrome, Frailty Syndrome, Aging
- Trial name
- NADage (NCT06208527)
- Testing
- Nicotinamide Riboside (NR)
- Where
- 2 sites in Norway
- Volunteers
- 100 people
- Sponsor
- Haukeland University Hospital
Frail Elderly Syndrome, Older Adults
A Digital Home-Based Physiotherapy Program for Active Aging
This clinical trial will aim to understand the effects of the TRAK-SILVER digital platform on pre-frail and older adults living at home, assessing its impact on physical activity level, emotional variables, and overall quality of…
- Trial name
- TRAK-SILVER (NCT06381336)
- Testing
- TRAK-SILVER platform
- Where
- Spain
- Volunteers
- 72 people
- Sponsor
- Trak Health Solutions S.L.
Thoracic, Thoracic Neoplasm
A Prospective Study Frailty for Esophagectomy and Lung Resection in Thoracic Surgery
The purpose of this study is to develop an all-encompassing frailty model using laboratory and functional studies. A frailty model will help us determine prior to surgery who will require rehabilitation and skilled nursing needs…
- Conditions
- Thoracic, Thoracic Neoplasm, Lung Cancer, Esophageal Cancer
- Trial name
- NCT03413449
- Testing
- Frailty model
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- The Cleveland Clinic
Frail Elderly Syndrome, Major Surgery
Multimodal Prehabilitation for Surgery in the Elderly: a Randomised, Prospective, Multicenter, Multidisciplinary Trial
This multicentric, randomised controlled trial is to the investigators knowledge the first implementation of a multimodal, multidisciplinary prehabilitation approach using knowledge from different specialties to lower…
- Trial name
- PREHABIL (NCT04461301)
- Testing
- Multimodal Prehabilitation
- Where
- Switzerland
- Volunteers
- 466 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Frailty, Surgery--Complications
Protocol for Patients Above 75 Years Undergoing Emergency Laparotomy
In the ProPEL study the effect of a protocol designed for elderly patients about to undergo emergency abdominal surgery will be investigated. The protocol addresses issues of both frailty and ceiling-of -care decisions.
- Conditions
- Frailty, Surgery--Complications, Outcome, Fatal, Frail Elderly Syndrome
- Trial name
- (ProPEL) (NCT04293653)
- Testing
- Protocol for patients above 75 undergoing emergency laparotomy or laparoscopy
- Where
- Norway
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Frail Elderly Syndrome, Surgery
Development and Validation of a Preoperative Frailty Index Using Health Administrative Data
The investigators will create a frailty index using health administrative data available for older people having surgery. The index will be based on the Canadian Study of Health and Aging Frailty Index and standard…
- Conditions
- Frail Elderly Syndrome, Surgery, Outcomes, Predictive Value of Tests
- Trial name
- NCT03354546
- Testing
- Frailty index
- Volunteers
- 511,285 people
- Sponsor
- Ottawa Hospital Research Institute
Elderly Infection, Frailty
Antibiotic Dosing in Geriatric Patients At the Emergency Department
In this pilot study, we will investigate whether - with the current dosing regimens, used in the Ghent University Hospital - pharmacodynamic targets regarding beta-lactam antibiotics (more specific Amoxicilline-Clavulanate…
- Conditions
- Elderly Infection, Frailty, Frail Elderly Syndrome, Infection, Bacterial
- Trial name
- AGED (NCT04436991)
- Testing
- Blood sampling, Sputum sample, Hemoculture
- Where
- Belgium
- Volunteers
- 180 people
- Sponsor
- University Hospital, Ghent
Frail Elderly Syndrome, Sarcopenia
Multidimensional Intervention in Pre-frail Patients Older Than 70 Years
Aging represents a huge advance in society and a health and social challenge. Spain has one of the highest life expectancies in the world, but other countries with the same demographic characteristics are ahead of us in quality…
- Trial name
- NCT04574271
- Testing
- Intensive dietary advice and exercise prescription, Usual dietary advice and exercise prescription
- Where
- Spain
- Volunteers
- 340 people
- Sponsor
- Endocrinology and Clinical Nutrition Research Center, Spain
Frailty, Frailty Syndrome
Smart Home Technologies for Assessing and Monitoring Frailty in Older Adults
This project aims to address the impact of frailty on older adults, particularly its connection to cognitive impairments such as dementia.
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome, Pre-Frailty
- Trial name
- NCT05961319
- Testing
- Smart-Home Monitoring
- Where
- 2 sites in Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Frailty, Aging
AGE SELF CARE: Promoting Healthy Aging Through a Group Visit Program
Aim 1: To assess the feasibility and acceptability of delivering AGE SELF CARE through virtual medical group visits by measuring recruitment rate, adherence, and participant satisfaction.
- Conditions
- Frailty, Aging, Frailty Syndrome, Frail Elderly Syndrome
- Trial name
- NCT06079762
- Testing
- AGE SELF CARE group visit program
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Brigham and Women's Hospital
Frail Elderly Syndrome
Comparative Analysis of Risk Factors and Prediction of Frailty Syndrome
Assessing frailty syndrome in elderly patients in Almaty To study the features of the clinical course in the group of patients with a pre-frailty and in the group with frailty syndrome
- Trial name
- FRAILTY-KZ (NCT06496022)
- Testing
- Frail scale, Barthel scale, SARC-F
- Where
- Kazakhstan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Asfendiyarov Kazakh National Medical University
Heart Failure, Frailty
INTEgRated Health CARE for Patients With Frailty and Heart Failure
Frailty, an aging-related syndrome of physiological decline characterized by marked vulnerability to adverse health outcomes, has attracted increasing attention in cardiology due to the growing elderly population with heart…
- Conditions
- Heart Failure, Frailty, Frail Elderly Syndrome, Symptom, Behavioral
- Trial name
- INTERCARE-HF (NCT06444321)
- Testing
- INTERCARE-HF
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Vestre Viken Hospital Trust