Clinical trials: Frail Elderly Syndrome
Malnutrition, Dementia
Fortified Foods in Older Inpatients
Malnutrition in older inpatients is a significant problem espicially among those with dementia. A number of methods have been used to tackle this issue and oral nutritional supplements (ONS) were proven to be the most effective…
- Conditions
- Malnutrition, Dementia, Aging, Frail Elderly Syndrome
- Trial name
- NCT03176030
- Testing
- Fortified Foods
- Where
- United Kingdom
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Non-ST Elevation Myocardial Infarction, Frail Elderly Syndrome
the Invasive and Conservative Strategies in Elderly Frail Patients With Non-STEMI
The role of a routine invasive strategy in frail patients with non-ST-segment elevation acute myocardial infarction is currently uncertain. We hypothesize that a routine invasive strategy will improve outcomes.
- Trial name
- MOSCA-FRAIL (NCT03208153)
- Testing
- Invasive, Conservative
- Where
- Spain
- Volunteers
- 167 people
- Sponsor
- University of Valencia
Frailty, Frailty Syndrome
Maintaining and imPrOving the intrinSIc capaciTy Involving Primary Care and caregiVErs
The POSITIVE platform offers the possibility of unsupervised monitoring of pre-frailty and frailty status in a community setting, to detect the onset of frailty and to assess its evolution.
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome
- Trial name
- POSITIVE (NCT04592146)
- Testing
- Frailty multicomponent intervention supported by POSITIVE, Frailty multicomponent intervention
- Where
- 3 sites in Poland, Spain and 1 more
- Volunteers
- 150 people
- Sponsor
- Hospital Universitario Getafe
Heart Failure With Preserved Ejection Fraction, Sarcopenia
Effectiveness of a Cardiac Rehabilitation Program in Elderly Patients With Heart Failure.
The main objective of the study is to assess the effectiveness of a cardiac rehabilitation program on functionality, measured by kinematic analysis, cardiorespiratory capacity, and ventricular ejection fraction in elderly…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Sarcopenia, Frail Elderly Syndrome, Comorbidities and Coexisting Conditions
- Trial name
- FUNNEL+ (NCT05393362)
- Testing
- Cardiac Rehabilitation Program (CR), Control Group (CG)
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- University of Malaga
Frail Elderly Syndrome, Aging
Autologous Stem/Stromal Cellular Stromal Vascular Fraction (cSVF) In Frailty-Aging Processes
With increasing age and health issues associated with aging, many systemic cellular and structural changes are known to occur. The intent of this trial is to determine the safety and efficacy of delivery of autologous cellular…
- Conditions
- Frail Elderly Syndrome, Aging, Degenerative Disease
- Trial name
- GARM-W (NCT03514537)
- Testing
- Microcannula harvest adipose stromal tissues, Centricyte 1000, Sterile Normal Saline IV Deployment of cSVF
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Healeon Medical Inc
Frail Elderly Syndrome
Protocol of Geriatric Rehabilitation in Patients of 60 and Older Who Live in Moscow Boarding Houses or Nursing Homes
After screening complex geriatric assessment (CGA) the participants will undergo geriatric rehabilitation programs. After termination of 21-day program, CGA will be repeated and subjects will get a program of long-term…
- Trial name
- POSTSCRIPTUM (NCT05740436)
- Testing
- Geriatric rehabilitation program based on CGA
- Where
- Russia
- Volunteers
- 420 people
- Sponsor
- Pirogov Russian National Research Medical University
Frail Elderly Syndrome
The Dynamics of Frailty in Older People
In the context of reduced resources and rising demand for unplanned care, the delivery of appropriate services to support people with frailty will be key to providing cost-effective, quality care for older people.
- Trial name
- NCT04139278
- Testing
- Observational
- Where
- United Kingdom
- Volunteers
- 300,000 people
- Sponsor
- University of Southampton
Pre-frail Elderly
The Effect of Cholecalciferol in Pre-frail Elderly
Vitamin D plays important role in musculoskeletal health and has been known to influence immune system. Inflammaging is one of risk factors that may contribute to development of frailty in elderly.
- Trial name
- NCT04847947
- Testing
- Cholecalciferol
- Where
- Indonesia
- Volunteers
- 120 people
- Sponsor
- Universitas Indonesia
Frail Elderly Syndrome, Frailty
Seated Physical Activity in Ageing
This trial will take the form of a feasibility study; designed to assess the feasibility of a proposed future clinical trial in this setting.
- Conditions
- Frail Elderly Syndrome, Frailty, Physical Activity
- Trial name
- SPAA (NCT03141866)
- Testing
- Exercise Intervention 1: Move It Or Lose It (MIOLI), Exercise Intervention 2: Machine-based resistance training intervention
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Birmingham
Chronic Obstructive Pulmonary Disease, Diabetes
Multi-level Integration for Patients With Complex Needs Facilitated by ICTs. A Shared Approach, Mutual Learning and Evaluation Are Expected to Create Synergies Among the Partners and to Bring Forward Integration of Care in Europe
CareWell will enable the delivery of integrated healthcare to frail elderly patients in a pilot setting through comprehensive multidisciplinary integrated care programmes where the role of ICTs can foster the coordination and…
- Conditions
- Chronic Obstructive Pulmonary Disease, Diabetes, Chronic Heart Failure, Frail Elderly Syndrome
- Trial name
- CAREWELL (NCT03042039)
- Testing
- New Care
- Where
- 5 sites in Croatia, Italy and 3 more
- Volunteers
- 1,712 people
- Sponsor
- Him SA
Frail Elderly Syndrome
Subjective Factors of Polymedication in the Elderly: a Qualitative Study of the Perceptions of Patients, Relatives and Referent Physicians.(DOSAGE)
The DOSAGE Study is a qualitative transversal study aiming to describe and understand the subjective factors of polymedication in the elderly population (75 years old and more), defined as 10 simultaneous drugs.
- Trial name
- DOSAGE (NCT03309228)
- Testing
- individual interviews
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Frailty Syndrome, Geriatric Health
Longitudinal Assessment of Maximal Inspiratory Pressure and Functional Capacity Following Inspiratory Muscle Training in Frail Older Adults (IMT-2)
This study aims to evaluate the effects of an 8-week inspiratory muscle training program on maximal inspiratory pressure and functional capacity in frail older adults aged 80 years and above.
- Conditions
- Frailty Syndrome, Geriatric Health, Respiratory Muscle Weakness, Age-Related Frailty
- Trial name
- NCT07328334
- Testing
- Inspiratory Muscle Training
- Volunteers
- 30 people
- Sponsor
- Universidad Francisco de Vitoria
Frail Elderly Syndrome, Surgery--Complications
Outcome of Very Old Patients Admitted for Elective Major Surgery, the Effect of Frailty
The aim of the study is to investigate the effect of frailty in patients ≥ 80 years admitted for elective major abdominal surgery.
- Trial name
- NCT03721471
- Testing
- Scoring of frailty
- Where
- Norway
- Volunteers
- 144 people
- Sponsor
- Haukeland University Hospital
Frailty, Frail Elderly Syndrome
Frailty Assessment in Vascular Hot Clinic Setting - Feasibility and Prognostic Value
A single-centre prospective study of feasibility assessing the suitability of introducing routine frailty screening in a controlled, and reproducible, outpatient department setting for Vascular Surgery patients.
- Conditions
- Frailty, Frail Elderly Syndrome, Surgery
- Trial name
- FAVOUR (NCT06040658)
- Testing
- Frailty assessment
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Frail Elderly Syndrome
Implementing, Evaluating, and Scaling Up of the Strengthening a Palliative Approach in Long Term Care (SPA-LTC) Program
This study will evaluate the implementation of the Strengthening a Palliative Approach in Long-Term Care (SPA-LTC) program using a cross-jurisdictional, effectiveness-implementation type II hybrid design (dual testing of clinical…
- Trial name
- NCT03935997
- Testing
- Strengthening a Palliative Approach in Long-Term Care (SPA-LTC) Program
- Where
- 4 sites in Canada
- Volunteers
- 594 people
- Sponsor
- McMaster University
End Stage Renal Failure on Dialysis, Frail Elderly Syndrome
The Effect of Intradialytic Exercise on the Physical Function of People Undergoing Hemodialysis
The investigators intend to recruit 50 patients into an intradialytic exercise study that will measure the impact of resistance bands exercises under the guidance of an exercise physiologist on the physical function of…
- Trial name
- IDEX (NCT03944824)
- Testing
- Exercise Plan using resistance bands, Modified Fried Frailty Scale
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Satellite Healthcare
Frail Elderly Syndrome
Validation of a Record-based Frailty Assessment According to the Multidimensional Prognostic Index
Background Various phenotype and cumulative frailty assessment tools have been developed and compared in research. For use in an in-hospital setting, a cumulative and graded frailty assessment method is preferred in order to…
- Trial name
- NCT03794674
- Testing
- No intervention.
- Where
- Denmark
- Volunteers
- 92 people
- Sponsor
- University of Aarhus
Frail Elderly Syndrome
Exercise Mediation on Hormonal, Immune and Psychological Well-being in Institutionalized Frail Older Women.
Frailty syndrome is a complex aging expression determined by ontogenetic and phylogenetic factors. Chronic stress has been shown to have immunosuppressive effects, to accelerate immunosenescence and to cause cumulative disorders…
- Trial name
- UC (NCT04435899)
- Testing
- Physical exercise
- Where
- Portugal
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Cognitive Impairment, Frail Elderly Syndrome
Cognition and the Immunology of Postoperative Outcomes
This research will test the hypothesis that immune system disequilibrium / dysfunction explains why preoperative cognitive impairment is a strong predictor of postoperative morbidity in older surgical patients.
- Conditions
- Cognitive Impairment, Frail Elderly Syndrome, Delirium, Surgery
- Trial name
- NCT04792983
- Testing
- No intervention
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Brigham and Women's Hospital
Frail Elderly Syndrome
Effects of WBV Associated With IMT on Inflammatory Markers, Body Composition, Muscle Strength and Thickness
Aging generates immune, muscular and functional changes. In the pre-frail elderly these changes may be increased and, therefore, preventive interventions are indicated to minimize the consequences of sarcopenia in this…
- Trial name
- NCT03689322
- Testing
- WBV + IMT
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco