Clinical trials: Free Flap
Surgical Flaps, Flap Failure Risk Factors
Adverse Events for Free Flap Surgery in Head and Neck Cancer
This is a cohort study collecting patients with head and neck cancer who underwent free flap surgery at a single medical center between January 2019 and January 2022.
- Conditions
- Surgical Flaps, Flap Failure Risk Factors, Hematoma Risk Factors, Thrombosis Risk Factors
- Trial name
- NCT06371365
- Testing
- Free Flap surgery
- Where
- Taiwan
- Volunteers
- 540 people
- Sponsor
- Kaohsiung Medical University
Head and Neck Cancers
Biomedical Innovation for Facial Bone Reconstruction in Oncology: BIOFACE PASS a Medico-economic Study Describing the Standard Pathway of Patients Treated by Free Bone Flap
The purpose of this study is to describe the standard of care pathway of patients treated by free bone flap for facial mandibullar or maxillar reconstruction after surgery for head and neck cancers.
- Trial name
- BIOFACE PASS (NCT06771336)
- Testing
- Questionnaires
- Where
- 9 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Toulouse
General Anesthesia
Effect of Goal-directed Fluid Therapy Using Stroke Volume Variation in Patients Undergoing Free Flap Reconstruction After Head and Neck Cancer Resection
Investigators hypothesized that goal-directed fluid therapy using stroke volume variation will improve postoperative recovery in patients undergoing free flap reconstruction after head and neck cancer resection.
- Trial name
- NCT02003066
- Testing
- Standard fluid therapy, Conservative fluid therapy
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Yonsei University
Glaucoma
Ahmed Glaucoma Valve Implantation; Graft-Free Short Tunnel Small Flap Versus Scleral Patch Graft
Glaucoma implants have been used for refractory glaucoma and are gaining popularity as a primary procedure in selected patients.
- Trial name
- NCT03551834
- Testing
- Conventional scleral patch graft glaucoma implantation, New surgical method (short tunnel small flap technique)
- Where
- Iran
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Free Tissue Flaps
Effect of Epidural Anesthesia on Blood Flow in Arterial Anastomosis of Free Flap
Comparing the changes of arterial anastomotic blood flow between general anesthesia alone and general anesthesia with epidural anesthesia in patients who undergoing free flap transposition using Duplex ultrasound.
- Trial name
- NCT03330808
- Testing
- Epidural anesthesia
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Asan Medical Center
Head and Neck Cancer, Patients Requiring a Free Flap Surgery
A Prospective Study Evaluating the Use of Intraoperative Stroke Volume Variation Via the FloTrac Device to Guide Fluid and Vasopressor Management in Head and Neck Free Flaps
This study aims to investigate whether the intraoperative use of the FloTrac device to guide fluid and vasopressor management during head and neck free flap surgery improves postoperative outcome.
- Trial name
- NCT02186938
- Testing
- FloTrac
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Medical University of South Carolina
Elective Reconstructive Surgery, Pain, Post Operative
The Efficacy and Safety of Lower Limb Nerve Blocks in Postoperative Analgesia for the Free Flap Donor Sites
The use of free fibular flaps and anterolateral thigh (ALT) flaps for repairing the oromandibular defects is well established, whereas few attentions were focused on postoperative analgesia for the donor area.
- Trial name
- NCT03071185
- Testing
- femoral nerve block, common peroneal nerve block
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xia Zhang
Free Flap Reconstruction
The Effect of Dexmedetomidine as an Adjuvant for Lower Limb Nerve Blocks
Peripheral nerve block has been recommended as the technique for postoperative pain management because it provides equivalent analgesia but with fewer adverse effects than either systemic or epidural analgesia.
- Trial name
- NCT03118076
- Testing
- 0.3% ropivacaine and 50 μg dexmedetomidine, Ropivacaine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xiaofeng Bai
Maxillary Neoplasms
Reconstruction of Maxillary and Midfacial Defects Using Latissimus Dorsi Scapular Free Flaps
Bony reconstruction of the midface with free tissue transfer is complex and challenging due to structural considerations such as the need for orbital support, patency of the nasal cavity, restoration of the palate and alveolus…
- Trial name
- NCT04522700
- Testing
- scapular free flap
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- hassan harby mohamed
Mandibular Tumors
Aesthetic Reconstruction of Onco-surgical Mandibular Defects Using FFF With and Without CAD/CAM Customized Cutting Guide
The purpose of this study is to compare Aesthetic results and operation time of free fibular flap with and without CAD/CAM customized osteotomy guide for reconstruction of mandibular defects.
- Trial name
- NCT03757273
- Testing
- FFF with CAD/CAM customized cutting guide, FFF without customized cutting guide
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Free Flap Transfer, Malignant Neoplasm
Observational Study of Outcomes After EchoMark and EchoSure-based Free Flap Monitoring
The purpose of this study is to evaluate the performance of the EchoMark and EchoSure as an ultrasound-based method of monitoring the viability of free flaps and patency of at-risk vessels.
- Trial name
- NCT03915717
- Testing
- EchoMark, EchoSure
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Sonavex, Inc.
Breast Reconstruction
Integrated Imaging System for In Vivo Visualization of Free Flap Perfusion Using Indocyanine Dye
The purpose of this study is to determine if the integrated imaging goggle (Smart Goggles) is as good as or better than current technology used to assess tissue perfusion (the extent of blood flow to the tissue) in certain types…
- Trial name
- NCT03625765
- Testing
- SmartGoggles
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Head and Neck Cancer, Intraoperative Complications
Coagulation and Vitamin K in Head and Neck Microvascular Free Flap Surgery
For patients with large head and neck tumors the recommended treatment, in many cases, is a combination of extensive surgery and postoperative radiotherapy.
- Conditions
- Head and Neck Cancer, Intraoperative Complications, Coagulation Disorder, Blood, Vitamin K Deficiency
- Trial name
- MVL-COAG (NCT04517461)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Region Skane
Microcirculation, Thermoregulation
Impact of Active Thermoregulation on the Microcirculation of Free Flaps
This study evaluates the impact of active thermoregulation on free flap microcirculation following free flap transfer. Thermoregulation is performed by passive warming, active warming (water circulation based device) and active…
- Conditions
- Microcirculation, Thermoregulation, Free Flap
- Trial name
- NCT02466594
- Testing
- Hilotherm Clinic®
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ulf Dornseifer, MD
Operation Time, Complication of Surgical Procedure
CAS Versus Traditional Freehand Technique for Mandibular Reconstruction With Free Vascularized Fibular Flap
A total of 153 patients who underwent mandibular reconstruction by VFF were included from Jan 1999 to Dec 2019. The mandibular resection and reconstruction were performed by four experienced oral and maxillofacial surgeons.
- Trial name
- NCT04965441
- Testing
- Computer-assisted surgery
- Where
- Belgium
- Volunteers
- 153 people
- Sponsor
- KU Leuven
Agitation, Delirium
Dexmedetomidine to Prevent Agitation After Free Flap Surgery
Reconstruction using microvascular free tissue flap has been an important management in patients with maxillofacial tumor. It is often characterised as long operation time, more traumatic and require restriction of patient's head…
- Trial name
- NCT01904760
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University
Head and Neck Cancer, Pain, Musculoskeletal
Continous Popliteal Block for Microvascular Free Flap Reconstruction in Ear, Nose and Throat Surgery
The aim of the study is to assess the effects of a continuous popliteal block on postoperative pain and recovery after major ear, nose and throat surgery with microvascular free flap reconstruction using a fibula graft.
- Trial name
- NCT03607227
- Testing
- Levobupivacaine, Saline Solution
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Region Skane
Surgical Wound
Single-Use Negative Pressure Wound Therapy for Free Flap Donor Sites
Various management options for free flap donor sites that require split thickness skin grafting exist. None has proven superior from both a patient care and a cost standpoint.
- Trial name
- NCT03340025
- Testing
- PICO Single Use Negative Pressure Wound Therapy System, xeroform gauze
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Best Tissue Constituent for Plantar Surface
Functional Outcome of Free Muscle Flaps Versus Free Skin Flaps for Post-traumatic Foot Plantar Surface Reconstruction
the investigators are trying to detect what is the best tissue constituent suitable for reconstruction of large post traumatic sof tissue defects of foot plantar surface
- Trial name
- NCT03152812
- Testing
- plantar surface reconstruction by free flaps
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- alhussein Ahmed Mahmoud El-Dahshan
Head and Neck Neoplasms, Pharyngectomy
Gastric Pull up Versus Free Flap Reconstruction for Laryngo-pharyngeal Defects
This study will compare the gastric pull up (GPU) with the free flap [(specifically, anterolateral thigh (ALT) and radial forearm free flap (RFFF)] techniques used in the reconstruction of alimentary tracts in patients who…
- Conditions
- Head and Neck Neoplasms, Pharyngectomy, Reconstructive Surgical Procedures
- Trial name
- GPU vs ALT (NCT03171558)
- Testing
- Gastric Pull Up, Free Flap Surgery
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia