Clinical trials: Freezing of Gait Symptoms in Parkinson Disease, open to volunteers
Parkinson Disease, Freezing of Gait Symptoms in Parkinson Disease
TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD
The goals of this clinical trial are to 1) learn how two different rehabilitation interventions for PD can reduce Freezing of Gait (FOG) in people with Parkinson's disease, as assessed by patients, clinicians, and wearable…
- Trial name
- NCT06815302
- Testing
- Experimental intervention, Active intervention
- Where
- 3 sites in United States, Brazil
- Volunteers
- 60 people
- Sponsor
- Oregon Health and Science University
Freezing of Gait, Parkinson Disease
DBS and Levodopa for Treating Freezing of Gait in Parkinson's Disease
Freezing of gait (FoG) is a complex symptom of Parkinson's disease (PD) that cause falls and disability in PD patients, heavily affect patients' autonomy and quality of life.
- Trial name
- NCT06316232
- Testing
- STIM ON plus, MED ON plus
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Istituto delle Scienze Neurologiche di Bologna
Parkinson Disease, Idiopathic, Freezing of Gait
Vortioxetine for Depressive Symptoms and Freezing of Gait in Parkinson Disease
The present study involves patients with Parkinson Disease (PD) suffering from freezing of gait (FOG) and depressive symptoms. The main aim of the study is evaluating the efficacy of vortioxetine in reducing moderate/severe FOG…
- Conditions
- Parkinson Disease, Idiopathic, Freezing of Gait, Depression Not Otherwise Specified
- Trial name
- NCT06805266
- Testing
- Vortioxetine (tablet)
- Volunteers
- 40 people
- Sponsor
- Marianna Amboni
Freezing of Gait Symptoms in Parkinson Disease
A System to Help With Freezing of Gait in Parkinson's Patients
The goal of this clinical trial is to learn if the ParkinSense system, a customizable, multimodal, and adaptable cueing system, can assist with freezing of gait (FOG) in patients with Parkinson's disease.
- Trial name
- NCT07542743
- Testing
- ParkinSense System
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Barron Associates, Inc.
Parkinson Disease, Freezing of Gait
Remote Mental Practice for Freezing of Gait in Parkinson's Disease
This single-blind, randomized controlled trial investigates the effects of a remotely delivered intervention based on mental practice (MP) combined with physical practice (PP) on freezing of gait (FOG) severity in people with…
- Trial name
- NCT06957405
- Testing
- MPPG (Mental and Physical Practice Group), PPG (Physical Practice Group)
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
Parkinson Disease, Freezing of Gait Symptoms in Parkinson's Disease
Brain-Machine Interface for Freezing of Gait
Gait problems in Parkinson's disease (PD), especially freezing of gait (FOG), greatly affect quality of life. While deep brain stimulation (DBS) is a highly effective treatment for many motor symptoms of PD, it is less effective…
- Trial name
- NCT06642519
- Testing
- Brain Stimulation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Toronto
Parkinson Disease, Gait Disorders, Neurologic
Correlation of STN-DBS Induced Visuospatial Changes and Freezing of Gait
The purpose of this research is to determine how deep brain stimulation (DBS) for Parkinson's disease affects attention and visuospatial function.
- Conditions
- Parkinson Disease, Gait Disorders, Neurologic, Visuospatial/Perceptual Abilities
- Trial name
- NCT06994728
- Testing
- Left STN-DBS on, right STN-DBS off first, Right STN-DBS on, left STN-DBS off first
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medical University of South Carolina
Parkinson Disease, Freezing of Gait
Use of CereGate Therapy for Freezing of Gait in PD
A Multi-Center, Controlled Study to Evaluate Use of CereGate Therapy to Reduce Freezing of Gait in Participants Diagnosed with Parkinson's Disease.
- Conditions
- Parkinson Disease, Freezing of Gait, Deep Brain Stimulation
- Trial name
- NCT05292794
- Testing
- CereGate Software; BSN cDBS Programmer; BSN Burst Programmer
- Where
- 7 sites in United States
- Volunteers
- 41 people
- Sponsor
- CereGate Inc.
Parkinson Disease, Freezing of Gait
Investigating the Neural Signature of Freezing of Gait in Parkinson's Disease
Freezing of Gait (FOG) is a disabling symptom of Parkinson's disease (PD) and a leading cause for falls. Current medical management is inadequate to alleviate FOG so there is need for improved treatments.
- Conditions
- Parkinson Disease, Freezing of Gait, Basal Ganglia Diseases, Brain Disease
- Trial name
- FOG-EEG (NCT06841718)
- Where
- Belgium
- Volunteers
- 28 people
- Sponsor
- KU Leuven
Parkinson&Amp;#39;s Disease, Freezing of Gait
Understanding Freezing of Gait Using Brain Signals and Virtual Reality
Freezing of gait - the inability to start or continue walking - is a particularly disabling problem in Parkinson's disease that has few treatment options.
- Conditions
- Parkinson&Amp;#39;s Disease, Freezing of Gait, Freezing of Gait Symptoms in Parkinson&Amp;#39;s Disease
- Trial name
- NCT07092995
- Testing
- VR Freezing Task, Dual Task, External Cueing
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of California, Los Angeles
Parkinson's Disease (PD), Freezing of Gait
Pharmacologically Modulating the Noradrenergic Arousal System to Reduce Freezing of Gait in Parkinson's Disease: a Multi-centre and Multi-modal Approach
The goal of this clinical trial is to learn if the medication atomoxetine can reduce freezing of gait in people with Parkinson's disease.
- Conditions
- Parkinson's Disease (PD), Freezing of Gait, Freezing of Gait Symptoms in Parkinson Disease
- Trial name
- AnTi-FREEZE (NCT07316296)
- Testing
- Atomoxetine
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Radboud University Medical Center
Freezing of Gait Symptoms in Parkinson Disease
CnF-DBS for Levodopa-Resistant FOG
The purpose of this trial is to study the safety, practicality, and effectiveness of deep brain stimulation (DBS) therapy in a brain region called the cuneiform nucleus (CnF) to treat disabling freezing of gait (FOG) in patients…
- Trial name
- CnF-DBS-FOG (NCT07781696)
- Testing
- Active Stimulation
- Where
- 3 sites in United States
- Volunteers
- 18 people
- Sponsor
- Iahn Cajigas
Freezing of Gait Symptoms in Parkinson's Disease, Deep Brain Stimulation
Imaging Biomarkers of FOG Response to DBS
For this study, the investigators are recruiting 54 individuals with Parkinson's Disease and Freezing of Gait (FOG) who are planning to undergo Deep Brain Stimulation (DBS).
- Trial name
- NCT06951906
- Testing
- fMRI
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Medical University of South Carolina
Parkinson Disease, Freezing of Gait Symptoms in Parkinson Disease
Pedunculopontine Nucleus Transcranial Ultrasound Stimulation as a Treatment of Freezing of Gait in Parkinson's Disease
This study is investigating the use of transcranial ultrasound stimulation (TUS) on the Pedunculopontine nucleus (PPN) in changing freezing of gait in people with Parkinson's disease.
- Trial name
- NCT07695233
- Testing
- Excitatory Stimulation, Inhibitory Stimulation
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Robert Chen