Clinical trials: Frequency Lowering
Overactive Bladder
Dose-Escalating Study of Propiverine Hydrochloride in Children Suffering From Overactive Bladder
The open-label dose-escalating two-centre study was designed to assess the pharmacokinetics as well as safety, tolerability and efficacy parameters of propiverine in patients 5-10 years of age suffering from…
- Trial name
- NCT00795925
- Testing
- propiverine hydrochloride
- Volunteers
- 30 people
- Sponsor
- APOGEPHA Arzneimittel GmbH
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Innovative Minimally Invasive Options in Treatment of Urinary Problems Related to Prostate Enlargement (BPH) in Men
For ageing men, Health related quality of life ( HRQoL) is challenged by two common issues: the onset of bothersome urinary symptoms attributable to prostate enlargement and diminishing ability to maintain normal sexual activity…
- Conditions
- Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia, Urinary Frequency/Urgency, Urinary Incontinence, Urge
- Trial name
- NCT03043222
- Testing
- UroLift as artifical device for prostatic urethral lift., Embospheres Microspheres as embolic agents for prostate artery embolization
- Where
- United States
- Sponsor
- St. Louis University
Urinary Bladder, Overactive, Lower Urinary Tract Symptoms
Use of Medium Frequency Electrotherapy in the Treatment of OAB, LUTS and Pelvic Pain
The aim of this study is to assess the effectiveness of medium frequency electrotherapy (interferential currents) treatment for overactive bladder (OAB), lower urinary tract symptoms (LUTS) and pelvic pain
- Conditions
- Urinary Bladder, Overactive, Lower Urinary Tract Symptoms, Pelvic Pain
- Trial name
- NCT03520166
- Testing
- Medium frequency electrotherapy (interferential currents), No treatment
- Volunteers
- 100 people
- Sponsor
- Fisioterapia Pélvica Avanzada Madrid, SRL
Stroke
Comparison of Frequency & Duration of Task Practice During Constraint Induced Movement Therapy
Stroke is a very serious medical condition, classically categorized as a neurological disorder that occurs due to obstructed blood flow to specific parts of the brain, and resultant death of that area.This obstructed blood supply…
- Trial name
- NCT04757467
- Testing
- Standard physiotherapy neuro-rehabilitation, Repetition-CIMT, Hour-CIMT
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Riphah International University
Urinary Incontinence
Validity and Reliability of the PRAFAB
PRAFAB assesses both the objective and subjective aspects of urinary incontinence. While differing from other questionnaires in this respect, it consists of only five questions.
- Trial name
- NCT07339657
- Testing
- Construct validity, Test-retest reliability
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Afyonkarahisar Health Sciences University
Overactive Bladder With Symptoms of Frequency, Urgency, and Urge Urinary Incontinence
The Effect Of Fluconazole On Pharmacokinetics Of Fesoterodine In Healthy Subjects
This study is designed to estimate the effect of fluconazole (200 mg BID for 2 days), a moderate CYP3A4 inhibitor on the pharmacokinetics of a single 8 mg oral dose of fesoterodine in healthy adult subjects.
- Trial name
- NCT00911235
- Testing
- Fesoterodine, fesoterodine plus fluconazole
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Pfizer
Overactive Bladder Syndrome
Efficacy of Transcutaneous Versus Percutaneous Posterior Tibial Nerve Stimulation in the Overactive Bladder.
The main aim of this study, is compare the effectiveness of transcutaneous posterior tibial nerve stimulation versus percutaneous posterior nerve stimulation in patients with overactive bladder.
- Trial name
- NCT04483817
- Testing
- Transcutaneous tibial nerve stimulation, Percutaneous tibial nerve stimulation
- Where
- Spain
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Fisiocore LC,SL
Urge Incontinence, Urinary Retention
Patient Registry to Study the Tined Lead Used With the InterStim System For Urinary Control
The purpose of this study is assess the long-term safety and effectiveness of the InterStim tined lead using a minimally invasive approach.
- Trial name
- NCT00225966
- Testing
- Device Medtronic InterStim Tined Leads Models 3889 and 3093
- Where
- 2 sites in United States
- Volunteers
- 153 people
- Sponsor
- MedtronicNeuro
Overactive Bladder, Urgency-frequency Syndrome
TEST-ON - Does iStim Reduce Urinary Urgency?
Overactive bladder (OAB) is a chronic disorder with an overall prevalence in the adult population of over 10%, but that may exceed 40% in elderly groups.
- Conditions
- Overactive Bladder, Urgency-frequency Syndrome, Urinary Frequency More Than Once at Night
- Trial name
- TEST-ON (NCT04957524)
- Testing
- iStim TENS unit and Transvaginal Probe
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Urinary Incontinence, Urge Incontinence
UCon Treatment of Overactive Bladder (OAB) in Males
UCon is a medical device for treatment of the symptoms of OAB and fecal incontinence (FI). It electrically stimulates the DGN through the skin to obtain modulated behaviour of the bladder musculature e.g., suppress undesired…
- Conditions
- Urinary Incontinence, Urge Incontinence, Nocturia, Urinary Frequency More Than Once at Night
- Trial name
- NCT05874375
- Testing
- Urge stimulation, Time limited stimulation
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- InnoCon Medical
Urinary Frequency, Urinary Urgency
Evaluation of Solifenacin in the Treatment of OAB Symptoms in Patients Who Have Successfully Undergone GreenLight Photoselective Vaporization of the Prostate (PVP)
The purpose of this study is to demonstrate that solifenacin post-operatively improves irritative symptoms in men whose obstructive symptoms have been relieved with the GreenLight laser outpatient procedure.
- Conditions
- Urinary Frequency, Urinary Urgency, Nocturia
- Trial name
- NCT00826527
- Testing
- Solifenacin PO
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Seattle Urology Research Center
Interstitial Cystitis, Chronic Interstitial Cystitis
Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial Cystitis
The purpose of this study is to assess the safety and efficacy of super-concentrated, freeze-dried aloe vera capsules for treatment of interstitial cystitis.
- Conditions
- Interstitial Cystitis, Chronic Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT04734106
- Testing
- Desert Harvest Aloe Vera Capsules
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Wake Forest University Health Sciences
Urinary Tract Infection, Leiomyoma
Lower Urinary Tract Infection (UTI) Evaluation in Women With Uterine Leiomyomata
To the investigators knowledge there is no research data published to date regarding the lower urinary tract symptoms in women with leiomyomas. The primary aims of this study are: 1.
- Trial name
- LOTUS (NCT01123603)
- Where
- United States
- Volunteers
- 860 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Urinary Urge Incontinence
The Effects of Sacral Neuromodulation for Urinary Urgency, Frequency, and Urge Incontinence
This prospective one group cohort study seeks to investigate the effects of sacral neuromodulation on urinary urgency, frequency and urge incontinence are maintained after the simulator device is temporarily turned off for a…
- Trial name
- NCT02776475
- Testing
- Sacral neuromodulation device turned off
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- TriHealth Inc.
Urinary Bladder, Overactive
A Study to Compare the Effectiveness and Safety of Fesoterodine and Placebo in an Elderly Population of Patients Who go to the Toilet Very Frequently Due to Overactive Bladder.
The drug being studied, fesoterodine fumarate helps prevent the bladder neck opening at unwanted times and has been shown to help patients with overactive bladder syndrome pass urine less frequently than before treatment.
- Trial name
- SOFIA (NCT00798434)
- Testing
- Fesoterodine fumarate
- Where
- 60 sites in Austria, Belgium and 13 more
- Volunteers
- 794 people
- Sponsor
- Pfizer
Interstitial Cystitis
Acupuncture for the Treatment of Interstitial Cystitis (IC) Symptoms
Acupuncture is a form of Chinese medicine that has been in existence for more than a thousand years. This clinical trial performs two types of acupuncture on traditional 'bladder' points to determine if one type demonstrates…
- Trial name
- NCT00094874
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Mary Elizabeth Groff Surgical Medical Research and Education Charitable Trust
Bladder, Lower Urinary Track Symptoms
Low-Energy Shock Wave Therapy for Overactive Bladder in Women With Metabolic Syndrome
Overactive bladder (OAB) is a common condition that causes urinary urgency, frequent urination, and nocturia, which can significantly affect quality of life.
- Conditions
- Bladder, Lower Urinary Track Symptoms, Metabolic Syndrome, Urgency-Frequency
- Trial name
- NCT07563764
- Testing
- Low-Energy Extracorporeal Shock Wave Therapy (LiESWT)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- KMUHIRB-F(I)-20230051
Urinary Bladder, Overactive
A Study to Test the Efficacy and Safety of the Beta-3 Agonist Mirabegron (YM178) in Patients With Symptoms of Overactive Bladder
The study is intended to test efficacy, safety and tolerability of two doses of once daily (qd) Mirabegron against placebo to treat patients with symptoms of overactive bladder.
- Trial name
- CAPRICORN (NCT00912964)
- Testing
- Mirabegron
- Where
- 151 sites in United States, Canada and 9 more
- Volunteers
- 2,030 people
- Sponsor
- Astellas Pharma Inc
Restless Legs Syndrome, Sleep Quality
Restless Legs Syndrome and Sleep Quality in Pes Planus
Pes planus, also known as flatfoot, is a common foot deformity that can affect the biomechanics of the lower limbs. However, its relationship with neurological conditions has not been studied extensively.
- Conditions
- Restless Legs Syndrome, Sleep Quality, Pain, Quality of Life
- Trial name
- FLAT-RLS (NCT07117591)
- Where
- Turkey (Türkiye)
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Bozok University
Overactive Bladder
Efficacy and Safety Study of Botulinum Toxin Type-A (Dysport®) in Continent Female Subjects Suffering From Idiopathic Overactive Bladder
The purpose of this study is to determine the optimal dose of botulinum toxin type A injected in the detrusor muscle to improve urinary symptoms, urodynamic parameters and quality of life of continent women suffering from…
- Trial name
- NCT00578097
- Testing
- Botulinum toxin type A
- Where
- 34 sites in Belgium, Czechia and 6 more
- Volunteers
- 81 people
- Sponsor
- Ipsen