Clinical trials: Functional Abdominal Pain Disorders
Constipation - Functional, Abdominal Distension
Stress Ball and Video Distraction During Pediatric Enema
This randomized controlled trial aims to evaluate the effects of stress ball use and video distraction during enema administration on fear, anxiety, and pain levels in children treated in the pediatric emergency department.
- Trial name
- SAVE (NCT07695428)
- Testing
- Stress Ball, Video Distraction
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Manisa Celal Bayar University
Migraine, Musculoskeletal Pain
Overlapping Pain Trajectory Study
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1.
- Conditions
- Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain
- Trial name
- COPC (NCT05752396)
- Testing
- Conditioned Pain Modulation, Offset Analgesia, Spatial Summation
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS)
Feasibility Study of a Guided Imagery Therapy Mobile Application for Functional Abdominal Pain Disorders in Children
Chronic abdominal pain is common among children, and the majority of cases are attributed to functional abdominal pain disorders. One approach to treating these disorders is by using psychological therapies.
- Conditions
- Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS), Functional Gastrointestinal Disorders (FGIDs), Gastrointestinal and Digestive Disorder
- Trial name
- NCT07222943
- Testing
- Guided Imagery Therapy
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Baylor College of Medicine
Functional Disorder of Intestine, Nausea Persistent
Efficacy of Ear Neurostimulation for Adolescents With Functional Abdominal Pain
This study evaluates the effectiveness of a neurostimulator applied to the outer ear for adolescents with functional gastrointestinal disorders.
- Trial name
- NCT02367729
- Testing
- Neurostimulator
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Medical College of Wisconsin
Pregnancy Related, Pelvic Floor Disorders
Effects of Reformer Pilates in Pregnant Women
Pregnancy is known as a period associated with important physiological and psychological changes in women's lives. There is moderately sufficient evidence in the literature to recommend supplementing prenatal physical activity…
- Conditions
- Pregnancy Related, Pelvic Floor Disorders, Pain, Back, Pain, Neck
- Trial name
- NCT06777771
- Testing
- Reformer pilates exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Izmir Democracy University
Functional Abdominal Pain Syndrome
Digital Psychological Intervention for Pediatric Functional Abdominal Pain Disorders in Primary Care
The project involves researching two psychological treatments for functional abdominal pain in children. The treatments will be offered to children as an early intervention, at primary care level.
- Trial name
- FAPD (NCT06481072)
- Testing
- Digital patient education, Digital patient education and iCBT
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Functional Abdominal Pain Syndrome
Therapeutic Effect of the Low FODMAP Diet in Children With Functional Abdominal Pain.
Diet components are important factors in pathogenesis of functional gastrointestinal disorders, especially in the irritable bowel syndrome.
- Trial name
- NCT03771027
- Testing
- The low FODMAP diet., The diet based on NICE guidelines.
- Where
- 2 sites in Poland
- Volunteers
- 33 people
- Sponsor
- University of Warmia and Mazury
Functional Abdominal Pain Disorder
Low-FODMAP Diet for Functional Abdominal Pain Disorders in Children.
This single-center, randomized, controlled, quadruple-blinded, superiority trial is performed to test the hypothesis that children with IBS and FAP-NOS who receive a low-FODMAP diet will have a lower mean abdominal pain intensity…
- Trial name
- NCT04528914
- Testing
- Low-FODMAP diet
- Where
- Poland
- Volunteers
- 42 people
- Sponsor
- Medical University of Warsaw
IBS (Irritable Bowel Syndrome), Bloating
A Study Evaluating the Impact of Regular FODMAP-targeting Digestive Enzyme Blend Use on Gastrointestinal Symptoms in Individuals With Self-Reported Bloating
This study is a randomized, double-blind, placebo-controlled, within-individual crossover trial designed to assess the impact of regular use of a consumer-grade FODMAP-targeting digestive enzyme blend (FODZYME®) on…
- Conditions
- IBS (Irritable Bowel Syndrome), Bloating, Abdominal Pain, Gut Health
- Trial name
- NCT07591584
- Testing
- FODMAP-targeting digestive enzyme blend
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kiwi Health Inc
Irritable Bowel Syndrome, Abdominal Pain
Peppermint Oil for the Treatment of Irritable Bowel Syndrome: Optimizing Therapeutic Strategies Using Targeted Delivery
Peppermint oil has shown to be effective in the treatment of Irritable Bowel Syndrome (IBS) symptoms in several meta-analyses. However, the level of evidence is moderate and peppermint oil remains relatively under-used in IBS.
- Conditions
- Irritable Bowel Syndrome, Abdominal Pain, Colonic Diseases, Functional
- Trial name
- PERSUADE (NCT02716285)
- Testing
- Ileocolonic release peppermint oil, Small intestinal release peppermint oil
- Where
- 4 sites in Netherlands
- Volunteers
- 190 people
- Sponsor
- Maastricht University Medical Center
Post-Acute COVID-19 Syndrome, Irritable Bowel Syndrome
Effect of Lecithin-based Curcuma and Boswellia on Post-acute COVID-19 IBS
This open-label study investigates the effects of lecithin-based formulations of Curcuma longa (Meriva™) and Boswellia serrata (Casperome™) extracts on post-acute COVID-19 irritable bowel syndrome (PCIBS) and irritable bowel…
- Conditions
- Post-Acute COVID-19 Syndrome, Irritable Bowel Syndrome, Abdominal Pain, Dysbiosis
- Trial name
- NCT06423586
- Testing
- Curcuma longa and Boswellia serrata extracts
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Irritable Bowel Syndrome
Milnacipran (Savella) in Irritable Bowel Syndrome (IBS)
Purpose: The investigators are proposing to examine the use of Savella® (Milnacipran) for treating irritable bowel syndrome (IBS) in women. Participants: Eligible participants will meet the Rome III diagnostic criteria for IBS.
- Trial name
- NCT01471379
- Testing
- Milnacipran
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Spencer Dorn, MD, MPH
Diarrhoea Predominant Irritable Bowel Syndrome
Quality of Life in Diarrhea-predominant Irritable Bowel Syndrome Taking GABA
The study aims to evaluate the impact on quality of life and abdominal discomfort of GABA and Melissa food supplement administration in patients with diarrhea-predominant irritable bowel syndrome.
- Trial name
- NCT06755489
- Testing
- GABA
- Where
- 2 sites in Italy
- Volunteers
- 20 people
- Sponsor
- University of Pisa
Irritable Bowel Syndrome, Digestive System Diseases
Effect of TU-100 in Patients With Irritable Bowel Syndrome (IBS)
The purpose of this study is to compare the effects of 5g of Daikenchuto (TU-100) three times per day (Daikenchuto [TU-100] is a botanical agent that modulates gastrointestinal nerves), and placebo on rectal sensation (sensation…
- Conditions
- Irritable Bowel Syndrome, Digestive System Diseases, Gastrointestinal Diseases, Intestinal Diseases
- Trial name
- NCT01890837
- Testing
- Daikenchuto (TU-100)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Tsumura USA
Functional Gastrointestinal Disorders, Abdominal Pain
Pepsin in Patients With Functional Dyspepsia
This non-interventional, observational study investigates the course of symptoms in patients with functional dyspepsia under treatment with a fixed combination of pepsin and amino acid hydrochloride over a period of approximately…
- Conditions
- Functional Gastrointestinal Disorders, Abdominal Pain, Dyspepsia, Nausea
- Trial name
- NCT03076411
- Testing
- Pepsin
- Where
- Germany
- Volunteers
- 97 people
- Sponsor
- Nordmark Arzneimittel GmbH & Co. KG
Functional Abdominal Pain Syndrome
Brain Mechanisms of Attention and Pain in Youth With FAPD
The objectives of this study are to identify neural mechanisms of increased pain in pediatric FAPD and examine mechanisms of disrupted attention in the presence of induced pain.
- Trial name
- NCT05892055
- Testing
- MRI Procedure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Michigan State University
Irritable Bowel Syndrome
Curcumin (Tumeric) in the Treatment of Irritable Bowel Syndrome: A Randomized-Controlled Trial
Evidence exists to support low-grade inflammation as the inciting factor leading to visceral hypersensitivity and alteration in motility in irritable bowel syndrome.In the medical literature,there is ample in vitro and in vivo…
- Trial name
- CuTIBS (NCT00779493)
- Testing
- curcumin
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Abdominal Pain
ADAPTing CBT for Pediatric Functional Abdominal Pain in Spain
Many youth experience ongoing stomach pain that does not have a clear medical cause. These conditions, called functional abdominal pain disorders, are common and can last for years.
- Trial name
- NCT07874867
- Testing
- Aim to Decrease Anxiety and Pain Treatment (ADAPT)
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Michigan State University
Gas Pain Related Intake
Efficacy and Tolerability of α-galactosidase in Treating Gas-related Symptoms in Children
The aim of this study was to evaluate the efficacy and tolerability of α-galactosidase in pediatric patients with predominant gas-related symptoms.
- Trial name
- NCT01595932
- Testing
- α-galactosidase
- Volunteers
- 52 people
- Sponsor
- Azienda Policlinico Umberto I
Irritable Bowel Syndrome, Inflammatory Bowel Diseases
A Personalized Approach to Abdominal Pain in Irritable Bowel Syndrome
Apart from its use to provide insight in IBS disease courses and in clinical research, ESM can provide patients with feedback about individual triggers of their symptoms, and thereby function as part of a personalized therapeutic…
- Conditions
- Irritable Bowel Syndrome, Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- PERCEPTIvE (NCT05998577)
- Testing
- ESM and Traqq
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Maastricht University Medical Center