Clinical trials: Functional Ability
Complications; Arthroplasty, Complications; Arthroplasty, Mechanical
Using MRI To Detect Soft Tissue Reactions And Implant Integration As Related To Implant Modularity
Patients with a total hip replacement may require early revision surgery due to an adverse local tissue reaction or bone resorption that occurs due to wear debris released from the implant.
- Trial name
- NCT02255331
- Where
- United States
- Volunteers
- 587 people
- Sponsor
- Hospital for Special Surgery, New York
Primary Ciliary Dyskinesia, Kartagener Syndrome
Physical Fitness, Exercise Capacity and Activities of Daily Living in Primary Ciliary Dyskinesia: a Retrospective Study
Decreased pulmonary function, peripheral muscle strength, and exercise capacity were reported in primary ciliary dyskinesia (PCD) in recent studies.
- Conditions
- Primary Ciliary Dyskinesia, Kartagener Syndrome, Immotile Cilia Syndrome
- Trial name
- NCT05040607
- Testing
- Data Collection
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Sleep, Quality of Life
Effects of a Healthy Lifestyle Program on Health Outcomes in Older Adults
Medical condition or disease under investigation : Quantitative and qualitative aspects of sleep, quality of life, functional ability and well-being in older adults (>55years) Purpose of clinical trial : To study the prospective…
- Conditions
- Sleep, Quality of Life, Functional Ability, Well-being
- Trial name
- NCT03576209
- Testing
- healthy lifestyle program
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Spinal Cord Injury
Clinical Evaluation of a Wheelchair Mounted Robotic Arm
The primary purpose of this project, is to evaluate the effect of a wheelchair mounted robotic arm (WMRA) to improve the functional independence of veterans with SCI.
- Trial name
- NCT00011609
- Testing
- Robotic Arm
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- US Department of Veterans Affairs
Dementia, Memory Loss
Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia
This project aims to examine the efficacy of remote, caregiver-led tES/brain stimulation intervention targeted to improve memory, mobility, and executive functioning among older adults with mild cognitive impairment or mild…
- Conditions
- Dementia, Memory Loss, Alzheimer Disease, Executive Dysfunction
- Trial name
- ACDCStim (NCT05661084)
- Testing
- Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (active)
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Hebrew SeniorLife
Dementia
Impact of Hospital Admission on Patients With Dementia
People with dementia have complex medical, social, and psychological needs and can be exacerbated by physical illness and the complex relationships between health care systems, patients and their families or caregivers.
- Trial name
- NCT02483065
- Testing
- mortality at discharge and 3-months after the admission in patients with and without dementia
- Volunteers
- 413 people
- Sponsor
- Hospital Galdakao-Usansolo
Ventricular Ejection Fraction
DMP115 in Patients With an Ejection Fraction Between 25%-40% to Evaluate the Use of Contrast Echocardiography to Assess Heart Function
The purpose of this clinical research study is to demonstrate the ability of Definity® enhanced versus unenhanced cardiac ultrasound to improve the accuracy and reproducibility of left ventricular ejection fraction (EF) when…
- Trial name
- NCT00401687
- Testing
- Definity® Vial for (Perflutren Lipid Microsphere) Injectable Suspension
- Where
- 10 sites in United States
- Volunteers
- 131 people
- Sponsor
- Lantheus Medical Imaging
BD
The Effect of Methylphenidate on Cognitive Abilities of Adults With Bipolar Disorder
The purpose of the study is to explore the effect of MPH on working memory, attention and decision making in adults with BD in remission or in depressed state.
- Trial name
- NCT02020200
- Testing
- MPH
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Shalvata Mental Health Center
Cerebral Palsy (CP)
Ultrasound or Whole Body Vibration on Knee Motion and Function in CP
This study compared the efficacy of therapeutic ultrasound (US) and whole-body vibration (WBV) as adjuncts to a standardized passive stretching regimen on improving knee joint range of motion (ROM) and functional capacity in…
- Trial name
- NCT07351292
- Testing
- ultrasound, whole body vibration
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Stroke, Hip Fractures
Outcome of Rehabilitation of Older People in Primary Health Care
The Outcome of Multi-Disciplinary, Structured Rehabilitation of Older People in a District Inpatient Rehabilitation Centre is better than in a Standard Primary Health Care Rehabilitation Programme in Short Term Beds in Nursing…
- Conditions
- Stroke, Hip Fractures, Osteoarthritis, Chronic Disease
- Trial name
- NCT01457300
- Testing
- Rehabilitation
- Where
- 2 sites in Norway
- Volunteers
- 302 people
- Sponsor
- University of Oslo
Cognitive Change, Memory; Disturbance, Mild
The Influence of Food for Special Dietary Use - Spread Enriched With 5-hydroxytryptophan, Theanine and Gamma-aminobutyric Acid on Psychophysiological Functions of Subjects Without Meaningful Organic and Cognitive Pathology
This is a single-centre, single-blind, two-arms, controlled study to assess the efficacy and safety of food for special dietary use enriched with 5-hydroxytryptophan, L-theanine and Gamma-aminobutyric acid in generally healthy…
- Conditions
- Cognitive Change, Memory; Disturbance, Mild, Emotional Regulation, Concentration Ability Impaired
- Trial name
- Spread Bogatyr (NCT05543811)
- Testing
- Food for special dietary use
- Where
- Russia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Federal State Budgetary Scientific Institution
Cognitive Function, Exercise Training
Aerobic Exercise Effects on Cognitive Function in Aging Individuals
Positive effects are exerted by participating in moderate exercise training with physical activity which positively affects body health, including cognitive abilities, among older adults.
- Trial name
- NCT06650345
- Testing
- supervised aerobic exercise
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Saud University
Aging, Aging Well
100-Year Human Aging Study
The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed clinical sites, mobile clinical sites, and an online participation pathway (current and future) to undergo…
- Conditions
- Aging, Aging Well, All-Cause Mortality, Mortality
- Trial name
- NCT07563777
- Testing
- Comprehensive Multi-System Clinical Screening
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Brain-damaged Patients
IRM Cognition in Patients With Head Trauma
Longitudinal descriptive study of a cohort of twenty brain-damaged patients for a two years period.
- Trial name
- NCT03181373
- Testing
- Cognitive rehabilitation program
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men, Hot Flashes
A Study to Learn if Elinzanetant Affects the Ability to Drive and Brain Function in Healthy Women
Researchers are looking for a better way to treat vasomotor symptoms (VMS), also known as hot flashes. Hot flashes are intense and sudden feelings of heat along with sweating and reddening of the skin.
- Trial name
- NCT06219902
- Testing
- Elinzanetant (BAY3427080), Zopiclone
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Bayer
Lower Extremity Fracture
The Effect of Tele-Nursing Application on Self-Care Ability and Daily Living Activities in Fracture Surgery Patients
This study aims to determine the effect of tele-nursing application based on Orem's Self-care Theory on self-care agency and daily living activities in trauma-related lower extremity fracture surgery patients.
- Trial name
- NCT06284759
- Testing
- post-discharge telenursing intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Gazi University
Mild Cognitive Impairment
Effects of Tai Chi on Cognition, I-ADLs, and HRQOL in Older People With MCI
The prevalence of older people with cognitive decline is increasing since the aging population is growing substantially worldwide. Cognitive impairment places older adults at high risk for functional disability.
- Trial name
- NCT03404765
- Testing
- Tai Chi
- Where
- Hong Kong
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Depressive Disorder, Somatoform Disorder
Physical Activity in Insurance Medicine: Effects on Patients With Psychiatric Disorders
We will conduct a randomized control trial to investigate whether and to what extent regular and guided group physical activity over 12 weeks (2 sessions à 1 hour/week) improves physical fitness and (physio-)psychological…
- Conditions
- Depressive Disorder, Somatoform Disorder, Anxiety Disorder, Personality Disorder
- Trial name
- PhysActIV (NCT01928264)
- Testing
- Physical activity
- Where
- Switzerland
- Volunteers
- 13 people
- Sponsor
- University Hospital, Basel, Switzerland
Dementia
Occupational Therapy Programme of Patients With Dementia Performing Activities of Daily Living
To assess the effectiveness of the Stimulation of Activities of Daily Living (SADL) Occupational Therapy programme on the independence of ADL by persons with dementia who are institutionalized.
- Trial name
- OTSALD (NCT02199353)
- Testing
- Stimulation of Activities Daily Living, Conventional ADLOccupational Therapy
- Where
- Spain
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Transfer Impairment
Evaluating the CG ASSIST Program for Caregiving Dyads
The CG ASSIST Project is a four-year study for older Veterans with transfer impairments and informal caregivers. CG ASSIST is an in-home training program for dyads designed to teach Veterans how to safely, skillfully, and (when…
- Trial name
- CG ASSIST (NCT02021565)
- Testing
- Immediate Intervention Group, Delayed Intervention Control Group
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development