Clinical trials: Functional Ability
Oncology
Validation of the GMFM-88 Scale and of the FAAP-O Scale in Pediatric Patients Affected by Cancer
The primary objective of this study is to validate the Gross Motor Function Measure Scale-88 (GMFM-88) on the Italian pediatric cancer population.
- Trial name
- FAAP-O (NCT04862130)
- Where
- 10 sites in Italy
- Volunteers
- 217 people
- Sponsor
- Associazione Italiana Ematologia Oncologia Pediatrica
Amyotrophic Lateral Sclerosis
Study of the Effects Strengthening Exercises in Individuals With ALS
Amyotrophic Lateral Sclerosis (ALS) is the most common motor neuron disease MND) among adults. Motor neurons in the spinal cord, brain stem, and cerebral motor cortex degenerate and create a variety of upper (UMN) and lower motor…
- Trial name
- NCT00204464
- Testing
- Exercise
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Saskatchewan
Down Syndrome
A Double-blind, Placebo-controlled Comparative Study and Open-label Extension Study to Confirm the Efficacy and Safety of E2020 in Subjects With Down Syndrome Having Regression Symptoms and Disabled Activities of Daily Living.
The purpose of this double-blind, placebo-controlled, comparative study and open-label extension study is to confirm the efficacy and safety of E2020 in subjects with Down syndrome having regression symptoms and disabled…
- Trial name
- NCT02094053
- Testing
- E2020-Donepezil hydrochloride
- Where
- 10 sites in Japan
- Volunteers
- 36 people
- Sponsor
- Eisai Co., Ltd.
Stroke
Evaluation of Sensorimotor Ankle Impairments in Chronic Stroke
The purpose of this study is to capture sensorimotor ankle function in a chronic stroke population through validation of novel, experimental metrics and their comparison with established, clinical measures of function.
- Trial name
- NCT06410989
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Healthy Subjects
Plasticity of the Compassionate Brain
The purpose of the study is to look at the long term effects of a complex socio-affective mental training program on a neuroscientific-, hormonal-, behavioral-, biological, and subjective measures-level.
- Trial name
- NCT01833104
- Testing
- Presence - Perspective - Affect, Presence - Affect - Perspective., Affect
- Where
- 2 sites in Germany
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- Max Planck Institute for Human Cognitive and Brain Sciences
Cognitive Ability, General
Nutrigenomics, PUFA, Iron and Cognition Amongst Under-two-year-old Indonesian Children
Rationale: Review on the positive effect of long chain polyunsaturated fatty acids (LCPUFA), especially docosahexanoic acid (DHA), supplementation on cognitive function in human using randomized controlled trials (RCTs) showed…
- Trial name
- NUPICO (NCT01504633)
- Testing
- DHA/EPA and iron supplementation
- Where
- Indonesia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Young Adults
Effect Of Resistance Training On Physical Fitness, Cognitive Ability, And Academic Performance In Young Adults
The goal of this study is to determine the effect of resistance training on physical fitness, cognitive ability, and academic performance in young adults.
- Trial name
- NCT06086808
- Testing
- Resistance Training, General Fitness and Toning
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Hypochondroplasia
Prospective Clinical Assessment Study in Children With Hypochondroplasia
This is a long-term, multicenter, non-interventional study of children ages 2.5 to <17 years with hypochondroplasia (HCH).
- Trial name
- HCH (NCT06410976)
- Where
- 25 sites in United States, Australia and 8 more
- Volunteers
- 150 people
- Sponsor
- QED Therapeutics, a BridgeBio company
Chronic Stroke, Non-use of the Paretic Upper Limb
Actimetry Monitoring of the Paretic Upper Limb in Chronic Post Stroke.
After a stroke, 80% of patients continue to have difficulty using their paretic upper limb in activities of daily living (ADL) despite post-stroke rehabilitation practices that aim to promote the use of the paretic upper limb.
- Trial name
- ParUse (NCT05581602)
- Testing
- Wearing bracelets (3-Axis Logging Accelerometer)
- Where
- 2 sites in France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
SCI - Spinal Cord Injury
tDCS and VI to Treat Neuropathic Pain and Function in SCI
Transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) will be applied for patient who suffer from neuropathic pain following spinal cord injury The tDCS treatment will be coupled with a video of a man…
- Trial name
- NCT03052244
- Testing
- tDCS+VI
- Volunteers
- 100 people
- Sponsor
- Loewenstein Hospital
Femoral Neck Fractures
Hemiarthroplasty or Internal Fixation for Displaced Femoral Neck Fractures
An estimated 1.6 million patients sustain a hip fracture every year, about half of these are intracapsular femoral neck fractures.
- Trial name
- NCT00464230
- Testing
- Bipolar hemiarthroplasty (Charnley/Hastings), Internal fixation with two parallel screws (Olmed)
- Where
- Norway
- Volunteers
- 220 people
- Sponsor
- Ullevaal University Hospital
Dry Eye Syndrome
The Effect of a New Emulsion in Dry Eye Patients on Tear Layer Aberrometry, Contrast Sensitivity, and Reading Ability
The purpose of this study is to investigate how the addition of a new emulsion artificial tear to the tear layer of dry eye and normal patients affects aberrometry, contrast sensitivity, and reading ability over time.
- Trial name
- NCT01013077
- Testing
- Optive, Soothe, New Emulsion, Soothe, New Emulsion, Optive, New Emulsion, Optive, Soothe
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Hemophilia, Upper Extremity
Comparison of Upper Extremity Functional Performance in Hemophilic and Healthy Children
The goal of this observational study is to evaluate the functional performance of the upper extremity joints (scapula, shoulder, elbow, and wrist) in haemophilic children and compare muscle strength and ADL limitations with…
- Conditions
- Hemophilia, Upper Extremity, Strength, Performance
- Trial name
- NCT06826209
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Stroke
A Rehabilitation Program Based on Daily Activities in Patients With Cerebrovascular Accident
Mixed qualitative and quantitative study, in two phases: Creation of a self-rehabilitation program based on people's daily living activities and designed with and for them.
- Trial name
- LARAQS (NCT05772663)
- Testing
- Personalized program of rehabilitation, Routine program of rehabilitation
- Where
- France
- Volunteers
- 158 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pyogenic Infections
NETs Formation in Patients With Recurrent Pyogenic Infections (NETS)
We aim to study if pathological NETs formation could be the underlying pathology among patients with recurrent infections and a normal screening of the immune system.
- Trial name
- NETs (NCT01112592)
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Osteopathic Manipulation, Postural; Defect
The Ability of Osteopathic Structural Evaluation to Assess Gait
Movement and loading asymmetry have been associated with injury risk for a variety of both acute and chronic musculoskeletal injuries.
- Conditions
- Osteopathic Manipulation, Postural; Defect, Somatic; Functional Disturbance
- Trial name
- NCT04860999
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Agitation, Dementia
Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY III)
A study to determine the safety and efficacy of BXCL501 dosing for episodes of agitation associated with dementia when they occur (given as needed [PRN]), for a maximum of 168 doses within a 12-week treatment period.
- Trial name
- NCT05665088
- Testing
- BXCL501
- Where
- 7 sites in United States
- Volunteers
- 13 people
- Sponsor
- BioXcel Therapeutics Inc
Cognitive Behavioral Therapy to Medical Treatment on Functional Ability of Patients With Vestibular Migraine
Efficacy of Cognitive Behavioral Therapy at Vestibular Migraine
The management of vestibular migraine is multifaceted and includes both pharmacological and non-pharmacological approaches. Aim of work Evaluate the efficacy of adding Cognitive Behavioral Therapy (CBT) to standardized Medical…
- Trial name
- NCT07849283
- Testing
- •Group A: Patients will receive Medical treatment only: Beta-blockers (Propranolol) , Calcium channel blockers, Group B: Cognitive Behavioral Therapy (CBT) +Medical treatment
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Functional Fitness, Cognitive Abilities
High-Intensity Exercise in Older Adults
The goal of this interventional study was to test the high-intensity interval training called Aphasia Physical Exercise (APEX) in healthy older adults. The main questions it aimed to answer were: 1.
- Trial name
- NCT06199661
- Testing
- APEX
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Spinal Fusion, Activities of Daily Living Following Complex Spinal Fusions
Impact of Body Habitus (Arm Span and Abdominal Girth) on Activities of Daily Living (ADL)
This study is being done to assess the impact of arm length and abdominal (belly) width on patient performance of daily self-care activities following multiple level spinal fusions.
- Trial name
- ADL (NCT04037059)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Duke University