Clinical trials: Functional Ability
Alzheimer's Disease
Effects of Rivastigmine Patch on Activities of Daily Living and Cognition in Patients With Severe Dementia of the Alzheimer's Type (ACTION) (Study Protocol CENA713DUS44, NCT00948766) and a 24 Week Open-label Extension to Study CENA713DUS44
The core study assessed the efficacy of a higher dose of rivastigmine 13.3 mg/24 h transdermally (15 cm^2 patch) compared to a lower dose of the rivastigmine 4.6 mg/24 h transdermally (5 cm^2 patch) in patients with Severe…
- Trial name
- ACTION (NCT00948766)
- Testing
- Rivastigmine 4.6 mg/24 h (5 cm^2), Rivastigmine 9.5 mg/24 h (10 cm^2), Rivastigmine 13.3 mg/24 h (15 cm^2)
- Where
- 95 sites in United States, Puerto Rico
- Volunteers
- 716 people
- Sponsor
- Novartis
Chronic Kidney Diseases, General Anesthesia
Effect of N-acetylcysteine on Renal Functioning of Chronic Kidney Diseases(CKD) Patients After General Anesthesia
Acute kidney injury (AKI) is one of the most serious and frequent complication of general anesthesia. Patients suffer from chronic kidney diseases (CKD) predispose to develop AKI.
- Trial name
- NCT01251029
- Testing
- N-acetylcysteine, Siran (N-acetylcysteine)
- Where
- Israel
- Sponsor
- Assaf-Harofeh Medical Center
COVID-19 Pandemic
Effects of Diagrammatic Breathing With and Without Resistance in Post Covid Patients on ADLs
Effects of diaphragmatic breathing exercise with and without resistance exercise program on functional capacity and activity of daily living in post covid patients
- Trial name
- NCT05543551
- Testing
- Diaphragmatic breathing with Resistance Training, diaphragmatic breathing with out resistance training
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Stroke
Comparative Effects of Motor Imagery and Mirror Therapy Versus Motor Relearning Program in Subacute Stroke Patients
Use of motor imagery, mirror therapy and motor relearning program in rehabilitation of people with stroke is on rise and these are unique and emerging techniques.
- Trial name
- NCT06308211
- Testing
- MOTOR IMAGERY+MIRROR THERAPY+ROUTINE PHYSICAL THERAPY, MOTOR RELEARNING PROGRAM+ROUTINE PHYSICAL THERAPY
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Stroke, Cardiovascular
Effects of Seated Tai Chi on Recovery Among Stroke Survivors
A randomized controlled trial using seated Tai Chi (TC) as a rehabilitation intervention will be conducted among subacute stroke survivors.
- Trial name
- NCT04138407
- Testing
- seated Tai Chi, Usual rehabilitation exercise
- Volunteers
- 320 people
- Sponsor
- Chinese University of Hong Kong
Scleroderma, Scleroderma (Limited and Diffuse)
Personalized Online Occupational Therapy Intervention for Adults With Scleroderma
This pilot exploratory randomized controlled trial will evaluate the feasibility, acceptability, and safety of a personalized online occupational therapy intervention for adults with scleroderma in Spain.
- Conditions
- Scleroderma, Scleroderma (Limited and Diffuse), Systemic Sclerosis (SSc)
- Trial name
- NCT07661836
- Testing
- Personalized Online Occupational Therapy Intervention, Usual Care
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Universidad de Zaragoza
Down Syndrome, Autism Spectrum Disorder
Neuro-Nutrition to Support Physiological Function and Cognitive Skills in People With Down Syndrome, Autism Spectrum Disorder, and ADHD
This study aimed to evaluate the impact of a specialized nutritional intervention on physiological performance, sleep quality, and cognitive abilities in individuals with neurodevelopmental disorders, specifically Down syndrome…
- Conditions
- Down Syndrome, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder (ADHD)
- Trial name
- NEURODIET-DSAA (NCT07165509)
- Testing
- T-2 Nutritional Supplement, Structured Dietary Program
- Where
- Mexico
- Volunteers
- 76 people
- Sponsor
- Elizabeth Guadalupe Ibarra Coronado
Activities of Daily Living, Chronic Obstructive Pulmonary Disease (COPD)
The Impact of Training on Self-Efficacy, Symptom Level, and Activities of Daily Living
This study is a randomized, controlled experimental trial with a pretest-posttest design, conducted to evaluate the effects of Pecha Kucha-based education on self-efficacy, symptom level, and activities of daily living in…
- Trial name
- NCT07482033
- Testing
- Intervention Group
- Volunteers
- 60 people
- Sponsor
- Istanbul Saglik Bilimleri University
Dementia, Alzheimer's Disease
Mass Practice of Activities of Daily Living in Dementia (STOMP)
People with Alzheimer's disease and related dementias present with changes in how they think, move and emotionally respond to daily life situations.
- Trial name
- STOMP (NCT02356055)
- Testing
- STOMP (Skill-building through Task-Oriented Motor Practice)
- Volunteers
- 32 people
- Sponsor
- University of Oklahoma
Obesity, Cognitive Ability, General
Physical Activity and Intermittent Exercise Training for Cardiovascular and Cognitive Gain in Obese Women
One hundred participants from a combination of (a) local advertisements and/or (b) those whose details are held on a research database (of previous volunteers indicating willingness to be contacted about future studies) will be…
- Conditions
- Obesity, Cognitive Ability, General, Cardiovascular Disease
- Trial name
- NCT02853279
- Testing
- Interval exercise training, Continuous exercise training (CON)
- Where
- 2 sites in United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Chronic Heart Failure With Preserved Ejection Fraction
Patient-reported Outcomes in Vericiguat-treated Patients With HFpEF
The primary hypothesis in this trial is that the treatment with vericiguat 10 mg or 15 mg in patients with HFpEF improves the KCCQ PLS (Kansas City Cardiomyopathy Questionnaire Physical limitation score) compared to placebo after…
- Trial name
- VITALITY-HFpEF (NCT03547583)
- Testing
- Vericiguat (BAY1021189) 2.5 mg, 5 mg or 10 mg IR tablets
- Where
- 177 sites in United States, Argentina and 19 more
- Volunteers
- 789 people
- Sponsor
- Bayer
Aging
The Ability of Pecan Consumption to Improve Vascular Function and Reduce Chronic Disease Risk in Aging Adults
Background: To date, there are no published studies on the effects of pecans on vascular function following a high-fat meal. Purpose: To examine the impact of daily pecan consumption for a 4-week period on vascular health and…
- Trial name
- NCT04385537
- Testing
- PECAN
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Physical Inactivity, Aging
Motivating Activity Through Text Communications - Helping Adults Increase Movement
The goal of this clinical trial is to compare the effect of different types of text messages on physical activity levels of middle-aged and older adults and to determine whether these messages are effective in adults age 40 and…
- Conditions
- Physical Inactivity, Aging, Cognitive Ability, Behavior Change
- Trial name
- MATCH AIM (NCT07593677)
- Testing
- Text Messaging Intervention
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Hemiplegic Cerebral Palsy
Kinesiotherapy on Upper Limb Function and Activities of Daily Living in Children With Hemiplegic Cerebral Palsy
This study will be randomized controlled trial, data will be collected from BASES special education school sialkot , Allama Iqbal Memorial Hospital, sialkot and Lahore.
- Trial name
- NCT07244081
- Testing
- control, experimental
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Spinal Cord Injuries (SCI), Upper Limb Function
FES Arm Cycling on Functional Ability and Strength in People With SCI
The goal of this feasibility study is to determine if Functional Electrical Stimulation (FES) arm cycling can be used to improve arm functional ability and arm strength in people with Spinal Cord Injury (SCI).
- Trial name
- NCT07385456
- Testing
- Functional electrical stimulation (FES) arm cycling
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Glasgow Caledonian University
Social Isolation in Older Adults, Quality of Life (QOL)
Virtual Senior Center
In a 3-group trial with randomization and follow-up for 12 months, we will compare use of the VSC as well as health and quality of life outcomes among 650 older adults in St.
- Conditions
- Social Isolation in Older Adults, Quality of Life (QOL), Activities of Daily Living
- Trial name
- VSC (NCT06946186)
- Testing
- Virtual Senior Center - GrandPad, Virtual Senior Center - No GrandPad
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Myasthenia Gravis, Adverse Childhood Experience
Psychological Health and Adverse Childhood Experiences in Myasthenia Gravis: Online Mental Health BMI Learning Program
This study evaluated psychological health in patients with myasthenia gravis (MG) using an online behavioral program called the "Positive Mental Health BMI Learning Program." The program consisted of four short video units…
- Conditions
- Myasthenia Gravis, Adverse Childhood Experience, Psychological Well-being, Mental Well-being
- Trial name
- NCT07291713
- Testing
- Positive Mental Health BMI Learning Program
- Where
- Taiwan
- Volunteers
- 77 people
- Sponsor
- Jiann-Horng Yeh
Hypertension, Cardiovascular Diseases
Effect of a Daily Life Activity-Based Awareness Training Program on Hypertensive Individuals
This randomized controlled study evaluated an education program based on the Roper, Logan, and Tierney model of daily living activities, supported by mindfulness, for hypertensive individuals.
- Conditions
- Hypertension, Cardiovascular Diseases, Self Efficacy, Treatment Adherence and Compliance
- Trial name
- NCT06547879
- Testing
- Hypertension Self Management Program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hacettepe University
Ageing
Fish Oil and Adaptations to Resistance Exercise in Older People
Skeletal muscle is the largest organ in the human body and has many important roles in determining our physical abilities and overall wellbeing.
- Trial name
- NCT02843009
- Testing
- Resistance Exercise Training, Supplementation
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Parkinson Disease
"Parkinson AKTIV - Non-pharmacological Treatments in an Innovative Parkinson's Network"
The purpose of this study is to evaluate the efficacy of an online platform that allows neurologists and therapists to exchange therapy recommendations, communicate assessments and plan physical therapy, occupational therapy as…
- Trial name
- ParkinsonAKTIV (NCT05251298)
- Testing
- Coordination through the online platform "JamesAKTIV"
- Where
- Germany
- Volunteers
- 370 people
- Sponsor
- University Hospital Muenster