Clinical trials: Functional Aging
Patient Compliance
Cognitive Regulation Training and Exercise Trial
The purpose of this double-blinded, randomized controlled study is to compare CORTEX (Cognitive Regulation Training and Exercise), a multi-faceted, center- and home-delivered- general and exercise-specific-active and traditional…
- Trial name
- CORTEX-II (NCT03124667)
- Testing
- Games, Videos
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Fall Prevention, Functional Independence
A Strategy for Fall Prevention in Aging Women
This retrospective study examined the effects of a 12-month training program on physical performance and functional ability in healthy older women.
- Conditions
- Fall Prevention, Functional Independence, Balance Impairment
- Trial name
- STABLE-WOMEN (NCT07481409)
- Testing
- Multicomponent and Stability Exercise Program
- Where
- Serbia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad
Sarcopenia
Effects of Eccentric Training Intervention in Older Adults
Sarcopenia leads to loss of muscle mass and muscle strength during the aging process. It has been reported that eccentric training has some positive effects on the preservation of eccentric strength, with less delayed onset…
- Trial name
- NCT04099316
- Testing
- Eccentric exercise, Conventional resistance exercise
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Aging
Ultrasound for Healthy Aging
The investigators will study the effects of an ultrasound bath device that uses low-frequency ultrasound on the healthy aging. Participants will have before and after ultrasound assessments of muscle and thinking skills, aging…
- Trial name
- NCT07168525
- Testing
- Ultrasound spa
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Vascular Aging
Oral Curcumin Supplementation in Middle-Aged and Older Adults Improves Vascular Function
The proposed study will assess the ability of curcumin, the active ingredient in the Indian spice tumeric, to improve the function of arteries with age.
- Trial name
- NCT01968564
- Testing
- High-dose curcumin pill, Low-dose curcumin pill
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Aging
The Effectiveness of Lifestyle Redesign Training in Elderly With Cognitive Decline
Taiwan is already an aging society due to the rapid increase of the aging population. To cope with this situation, it is necessary to make preparations for the care of the elderly.
- Trial name
- NCT04689763
- Testing
- Training
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Chang Gung Memorial Hospital
Aging, Cognitive Aging
Music Improvisation Training on Cognitive Function in Older Adults
This project will study the effects and mechanisms of a music improvisation training intervention on self-regulation of older adults with and without MCI.
- Conditions
- Aging, Cognitive Aging, Cognitive Impairment, Cognitive Training
- Trial name
- Music Training (NCT06721390)
- Testing
- Piano Improvisation, Music Listening
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Physical Disability, Cognitive Impairment
Improving Aging in Place in Subsidized Housing
This pilot study will evaluate the feasibility and preliminary effectiveness of an adapted version of the Function Focused Care intervention, delivered by telephone, for improving aging in place for older adults living in…
- Conditions
- Physical Disability, Cognitive Impairment, Physical Activity
- Trial name
- NCT04212442
- Testing
- Independent Living Program for Affordable Housing.
- Where
- 13 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Vascular Endothelium, Microvascular Circulation
Healthy Age-dependent Reference Values for Microvascular Structure and Function
The greatest challenge in our ageing society are cardiovascular diseases such as stroke, heart attack, peripheral artery disease of the legs with non-healing wounds (ulcers), or diabetes.
- Conditions
- Vascular Endothelium, Microvascular Circulation, Arterial Stiffness, Healthy Ageing
- Trial name
- NCT04897191
- Testing
- Age
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Cognitive Decline
Cognitive Function in Elderly Marathon Runners
There is substantial research on the effects of physical exercise on cognitive functions. However, less attention has been paid on the requirements of training intensity and length to enhance cognitive abilities in the elderly.
- Trial name
- APSOEM (NCT01045031)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Sarcopenia
The Krill Ageing Muscle Mechanisms (KAMM) Study
This study aims to determine the mechanisms via which krill oil supplementation increases muscle strength and whether this translates to improvements in gait and functional characteristics in older adults.
- Trial name
- KAMM (NCT06296875)
- Testing
- Vegetable oil, Krill oil
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Healthy Aging
Mindfulness and Attention Training Intervention to Lower Distractibility in Aging
The goal of this interventional study is to test the efficacy of combined mindfulness meditation training and cognitive training on brain function and cognition in healthy older adults.
- Trial name
- MATILDA (NCT05974605)
- Testing
- MM+HighC
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Aging, Physical Activity
Effects of Regular Exercise on Cerebrovascular Reserve in Older Adults
While it is well established that physical inactivity is a modifiable risk factor for vascular disease and cognitive decline, the mechanism by which exercise exerts its protective effect on the cerebral circulation and cognition…
- Conditions
- Aging, Physical Activity, Cognitive Function
- Trial name
- BIM (NCT03158337)
- Testing
- Aerobic exercise
- Where
- Canada
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Aging, Healthy
ACTIVE: Advanced Cognitive Training for Independent and Vital Elderly
The purpose of the ACTIVE study was to test if cognitive training interventions could maintain functional independence in elders by improving basic mental abilities, with follow-up assessments through five years.
- Trial name
- ACTIVE (NCT00298558)
- Testing
- Cognitive Training
- Where
- 7 sites in United States
- Volunteers
- 2,832 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Physical Inactivity, Healthy
Supervised Center-based vs. Unsupervised Home-based Exercise Programs (PRO-Training)
The superiority of supervised center-based training programs compared with unsupervised home-based ones in older adults remains unclear, and no evidence exists on whether including a motivational component could moderate these…
- Conditions
- Physical Inactivity, Healthy, Older Adult
- Trial name
- PRO-Training (NCT05619250)
- Testing
- Unsupervised home-based exercise group without motivational intervention (UNSUP), Unsupervised home-based exercise group with motivational intervention (UNSUP+), Supervised center-based exercise group without motivational intervention (SUP)
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Aging, Functional Status
Remote Physical and Cognitive Training Effects in Older Adults at Increased Risk of Clinical-functional Vulnerability
This study is a randomized, single-blind, parallel, controlled, superiority trial. The main objective is to verify the chronic effects of a remote 12-week low-intensity physical training program alone or in combination with…
- Trial name
- NCT05309278
- Testing
- Physical training, Cognitive training
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Exercise Training, Neurocognitive Function
Exercise and Neurocognition in Adults Relative to ApoE Genotype
The current project is a single-blinded, double-arm, 6-month randomized controlled trial aiming to assess the effects of a integrated intervention program on neurocognitive function with respect to event-related potential in…
- Conditions
- Exercise Training, Neurocognitive Function, Aging
- Trial name
- NCT05101174
- Testing
- Integrated Intervention Group (IIG), Control Group
- Where
- 2 sites in Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Aging, Health Promotion
Social Prescribing Intervention for Health Promotion in Community-Dwelling Older Adults
This study evaluates the effects of a social prescribing intervention on health promotion outcomes in community-dwelling older adults.
- Conditions
- Aging, Health Promotion, Mental Health
- Trial name
- NCT07540117
- Testing
- Mindfulness Meditation and Walking-Pole Exercise
- Where
- Taiwan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Aging Problems, Balance; Distorted
Comparison of the Effects of Different Living Environments in Geriatric Individuals: A Pilot Study
In Turkey, 63% of geriatric people who make up approximately 8.3% of the entire population live in their own living environment, 36% live with their children and 1% live in nursing homes.
- Conditions
- Aging Problems, Balance; Distorted, Pain, Quality of Life
- Trial name
- NCT04873791
- Testing
- Assessment of geriatric individuals living in home environment and nursing home.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dementia, Alzheimer Disease
Effects of Remote-based Resistance Training on Cardiometabolic Risk Factors, Cognitive Function, and Quality of Life in Adults Living With Alzheimer's Disease and/or Related Dementias
The investigators aim to study the effects of a 24-week remote-based resistance exercise training program on cardiovascular disease risk factors, cognitive function, and quality of life in older adults living with mild cognitive…
- Conditions
- Dementia, Alzheimer Disease, Dementia, Vascular, Lewy Body Disease
- Trial name
- NCT05004558
- Testing
- Remote-based Resistance Exercise Training
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Drexel University