Clinical trials: Functional Bowel Disorder, open to volunteers
Irritable Bowel Syndrome (IBS), Fibromyalgia (FM)
Evaluating the Added Benefit of Osteopathic Care to a Flexi-FODMAP Diet in Fibromyalgia Patients With Irritable Bowel Syndrome
Dietary modifications are often recommended as first-line treatment for irritable bowel syndrome, with the FODMAP diet being the most effective intervention to improve global gastrointestinal symptoms.
- Trial name
- POISE-IBS-RCT (NCT07176078)
- Testing
- Osteopathic care, Flexi-FODMAP Diet
- Where
- Belgium
- Volunteers
- 96 people
- Sponsor
- Universitair Ziekenhuis Brussel
Abdominal Pain/ Discomfort, Irritable Bowel Syndrome
The Mechanism Underlying the Analgesic Effect of the Music of IBS Pain
The proposed pilot study aims to assess the underlying mechanisms of the MBI on IBS pain and the feasibility of using novel technology in the outcome measurements.
- Trial name
- NCT06706778
- Testing
- Music intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
IBS - Irritable Bowel Syndrome
Ethosuximide and Pentoxifylline in the Treatment of Abdominal Pain Related to Irritable Bowel Syndrome
Ethosuximide and pentoxifylline in the treatment of abdominal pain related to irritable bowel syndrome
- Trial name
- NCT04217733
- Testing
- pentoxyifylline, Mebeverine, ethosuximide
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Irritable Bowel Syndrome (IBS)
Probiotic Mixture (L. Rhamnosus GG and L. Plantarum 299V) In Pediatric Irritable Bowel Syndrome
What is this study about? This clinical study aims to investigate whether a specific combination of probiotics-Lactobacillus rhamnosus GG and Lactobacillus plantarum 299V-can help children and adolescents with Irritable Bowel…
- Trial name
- PRIME (NCT07125625)
- Testing
- Experimental arm: probiotic
- Where
- 3 sites in Italy
- Volunteers
- 124 people
- Sponsor
- University of Bari
Functional Dyspepsia, Irritable Bowel Syndrome
Psychoemotional Status and Functional Gastrointestinal Disorders
This prospective cohort study will evaluate the influence of psychoemotional status on the clinical course and quality of life of adult patients with functional dyspepsia and/or irritable bowel syndrome diagnosed according to…
- Trial name
- NCT07539051
- Testing
- Questionnaire and Symptom Assessment, Helicobacter pylori Status Assessment
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- Center of New Medical Technologies
Menopause, Perimenopausal Disorder
Pelvic Floor Symptoms Across Menopausel Stages
The menopausal transition is associated with substantial hormonal alterations that may adversely affect lower urinary tract function, bowel function, and sexual health.
- Trial name
- NCT07690137
- Testing
- Assessment for Lower Urinary Tract Symptoms, Assessment for Bowel Symptoms, Constipation Severity Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Bezmialem Vakif University
Non-celiac Gluten Sensitivity
Tolerability of an Ancient Grain in Patients With Non-Celiac Wheat Sensitivity
Patients suffering from wheat-related troubles, in absence of celiac disease or wheat allergy diagnosis, can suffer from non-celiac wheat sensitivity (NCWS).
- Trial name
- NCT06191432
- Testing
- Administration of Triticum Monococcum flour, Administration of Triticum Aestivum flour
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- University of Palermo
Irritable Bowel Syndrome (IBS)
Synbiotic Supplement With Botanical Extracts for Gut Microbiota Balance in Irritable Bowel Syndrome
The goal of this clinical trial is to evaluate whether a synbiotic dietary supplement containing botanical extracts and multiple probiotic strains can improve gastrointestinal symptoms and modulate gut microbiota composition in…
- Trial name
- NCT07475299
- Testing
- Synbiotic supplement containing probiotic strains, botanical extracts, magnesium, vitamin B1, and L-theanine designed to support gut microbiota balance.
- Where
- Romania
- Volunteers
- 8 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Fibromyalgia, Irritable Bowel Syndrome
Exercise Interventions and Dietary Advice in Fibromyalgia and IBS
Fibromyalgia (FM) is a chronic disorder marked by widespread musculoskeletal pain, fatigue, sleep disturbances, and cognitive difficulties. Patients often experience hyperalgesia, allodynia, and muscle weakness.
- Trial name
- FM-IBS (NCT06923800)
- Testing
- Combined Exercise Program + A specific nutritional plan for individuals with IBS, Aerobic Exercise + A specific nutritional plan for individuals with IBS
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Irritable Bowel Syndrome (IBS)
Diet and Motility in IBS
The goal of this observational study is to identify factors that influence symptoms in children with irritable bowel syndrome (IBS), to find ways to make diet treatments work better and possibly create personalized plans to help…
- Trial name
- IBS (NCT07283341)
- Testing
- Wireless Patch System
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Ulcerative Colitis
Outcomes of Transanal Tran-section and Single-stapled (TTSS) Ileal Pouch-Anal Anastomosis
This study aims to compare the functional and surgical outcomes of Ulcerative Colitis (UC) patients undergoing Transanal Transection and Singl-Stapled (TTSS) versus Double-stapled Ileal Pouch-Anal Anastomosis (IPAA)
- Trial name
- TTSS-Pouch (NCT06331637)
- Testing
- Transanal Transection and Single-Stapled anastomosis (TTSS), Double-stapled anastomosis
- Where
- Italy
- Volunteers
- 174 people
- Sponsor
- Istituto Clinico Humanitas
Healthy, IBS - Irritable Bowel Syndrome
Microbiome Sampling in GI Disease With a Focus on Small Intestinal Microbial Assessment
GI disorders are influenced by the gut microbiome. To date, sampling of the small intestine in GI disorders has been limited. The investigators plan to sample the small intestinal contents during endoscopy for research purposes.
- Conditions
- Healthy, IBS - Irritable Bowel Syndrome, Inflammatory Bowel Diseases
- Trial name
- NCT06066866
- Testing
- endoscopic sampling of luminal fluid
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Stanford University
IBD (Inflammatory Bowel Disease)
Neurological Manifestations in Children Diagnosed With Inflammatory Bowel Disease
screen for neurologic and psychiatric disorders in children and adolescents with IBD.
- Trial name
- NCT07247994
- Volunteers
- 44 people
- Sponsor
- Bishoy Shehata Fahim
Non Celiac Wheat Sensitivity, IBS (Irritable Bowel Syndrome)
NCWS or IBS/FD in Relatives of CD Patients
Over 50% of non-celiac wheat sensitivity (NCWS) patients are HLA DQ2/DQ8 positive and often have a Celiac Disease (CD) family history.
- Conditions
- Non Celiac Wheat Sensitivity, IBS (Irritable Bowel Syndrome), Functional Dyspepsia, Celiac Disease
- Trial name
- NCT07584473
- Testing
- Wheat-Free Diet
- Where
- 2 sites in Italy
- Volunteers
- 600 people
- Sponsor
- University of Palermo
Irritable Bowel Syndrome
A Well-Being Intervention for People With IBS
The purpose of this randomized behavioral clinical trial is to examine whether a well-being intervention can improve both psychological well-being and physical outcomes in adults with Irritable Bowel Syndrome (IBS).
- Trial name
- NCT07600047
- Testing
- Well-Being Intervention
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Wisconsin, Madison
Obesity
Effect of Oral Calcium Butyrate Supplementation in Obesity
Obesity is characterized by gut microbiota dysbiosis, in which beneficial metabolites such as butyrate are reduced. Butyrate is a short-chain fatty acid produced by microbial fermentation that plays a key role in maintaining…
- Trial name
- Pacayeliztli (NCT07583017)
- Testing
- Calcium butyrate
- Where
- Mexico
- Volunteers
- 42 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Irritable Bowel Syndrome
A Single-arm, Open-label Clinical Trial to Evaluate the Effect of SMT04 in Irritable Bowel Syndrome (IBS)
Probiotic supplements improve IBS symptoms through manipulation of the gut microbiota. Metabolites derived from microbiota metabolism and host-microbiota co-metabolism have an impact on host intracellular signalling pathways.
- Trial name
- NCT06636513
- Testing
- SMT04 (M3XTRA)
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Changi General Hospital
Post Operative Patients
The Food Network Effect
The goal of this clinical trial is to learn if exposure to food related visual stimuli during the postoperative period can improve gastrointestinal recovery after abdominal surgery in adult patients.The main questions it aims to…
- Trial name
- NCT07618559
- Testing
- Food Related Visual Stimuli Exposure
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Casey Morehouse, DO