Clinical trials: Functional Cardiac Disorder
Peripheral Vascular Diseases, Heart Failure
Peripheral Artery Disease in Vastmanland
The main purposes of this study are: to describe the prevalence and degree of reduced left ventricular function and hypertrophy in patients with peripheral arterial disease in comparison to controls from the general population…
- Conditions
- Peripheral Vascular Diseases, Heart Failure, Ventricular Dysfunction
- Trial name
- PADVa (NCT01452165)
- Where
- Sweden
- Volunteers
- 457 people
- Sponsor
- Uppsala University
Heart Failure, Congestive
Effects of CPAP on Ventricular Function Modifications
To assess modifications of ventricular function induced by CPAP (Continuous Positive Airway Pressure).
- Trial name
- NCT00455611
- Testing
- CPAP (Continuous Positive Airway Pressure)
- Where
- Italy
- Sponsor
- Ospedale S. Giovanni Bosco
Heart Failure, Implantable Cardioverter Defibrillator (ICD)
Upper Extremity Function in Patients With Reduced Ejection Fraction Heart Failure and Cardiac Implantable Electronic Devices
The aim of this study is to evaluate in detail the factors that determine upper extremity function, determine its effect on prognosis, hospital admission, hospitalization, and mortality, and examine the results according to the…
- Conditions
- Heart Failure, Implantable Cardioverter Defibrillator (ICD), Cardiac Resynchronisation Therapy (CRT), Reduced Ejection Fraction Heart Failure
- Trial name
- NCT07253909
- Testing
- Not applicable- observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Hacettepe University
Long QT Syndrome
Pharmacokinetics of Eleclazine in Adults With Normal and Impaired Hepatic Function
The primary objective of this study is to evaluate the pharmacokinetic (PK) profile of oral eleclazine and its metabolite, GS-623134, in participants with normal and impaired hepatic function.
- Trial name
- NCT02412098
- Testing
- Eleclazine
- Where
- 7 sites in United States, Germany and 2 more
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Gilead Sciences
Amyloidosis, Cardiac Amyloidosis
Study of Olfactory Disorders in Patients With Cardiac Amyloidosis
Amyloidosis is a disease caused by the continuous accumulation of fibrillary proteins in the extracellular matrix causing the architecture of different organs to be disrupted. The prevalence of the disease increases with age.
- Conditions
- Amyloidosis, Cardiac Amyloidosis, Olfactory Loss, Hyposmia
- Trial name
- AMYLODOR (NCT04661800)
- Testing
- Sniffin's stick test
- Where
- France
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cirrhosis, Liver, Acute-On-Chronic Liver Failure
Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Refractory Ascites
Point-of-care echocardiography (POC-Echo) is used to determine left ventricular systolic and diastolic dysfunction (LVDD), inferior vena cava (IVC) dynamics and volume status in cirrhosis and Acute-on-chronic liver failure ACLF…
- Conditions
- Cirrhosis, Liver, Acute-On-Chronic Liver Failure, Refractory Ascites, Ascites
- Trial name
- NCT05700708
- Testing
- Echocardiographic assessment
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Acute Kidney Injury, Cardiac Valve Disease
Impact of Nicotinamide Riboside (NR) on Kidney Function in Patients Undergoing Cardiac Surgery
Acute kidney injury (AKI) associated with cardiac surgery is the most important complication in adult patients undergoing open heart surgery and is associated with increased mortality and morbidity.
- Trial name
- AKI-RCT (NCT06521307)
- Testing
- Nicotinamide riboside
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Atrial Fibrillation, Renal Insufficiency
Renal Function Post Cardioversion for Atrial Fibrillation
Atrial fibrillation is a common arrhythmia which requires electrical cardioversion in many patients in order to regain sinus rhythm.
- Conditions
- Atrial Fibrillation, Renal Insufficiency, Cardioversion
- Trial name
- AFCARD-II (NCT02742207)
- Testing
- Electrical atrial fibrillation Cardioversion, Cardioversion
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Hadassah Medical Organization
Thoracic Surgery, Postoperative Period
Efficacy of Triburter on Respiratory Muscle Function in Patients After CABG in Cardiac Rehabilitation Phase II
Post-surgery patients have muscle impairments, especially in the respiratory muscles, because the anesthesia, surgical incision, mechanical ventilation, pain, and prolonged postures, affect the mechanical condition of respiratory…
- Conditions
- Thoracic Surgery, Postoperative Period, Weakness, Muscle
- Trial name
- NCT05496049
- Testing
- Triburter, Incentive spirometry
- Where
- Colombia
- Volunteers
- 30 people
- Sponsor
- Fundación Cardiovascular de Colombia
Cardiovascular Disease
Spinal Cord Injury: Endurance, Strength and Cardiac Function Induced by Efficient Training Protocols
1. Measurements of peak oxygen uptake (VO2peak) during passive leg cycling (PLC) combined with arm crank ergometry (ACE), leg vascular occlusion (100mmHg above systolic BP) combined with ACE, and FES isometric contractions…
- Trial name
- NCT00987155
- Testing
- Ergometry
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Intrauterine Growth Restriction, Cardiopulmonary Disease
IUGR, Respiratory Muscle Function, and Exercise Capacity in Childhood
The study hypothesis is that intrauterine growth restriction (IUGR) may have long-term effects on respiratory muscle (RM) function, thus leading to reduced exercise capacity later in life.
- Trial name
- NCT03368755
- Testing
- Cardiopulmonary Exercise Testing, Respiratory Muscle Strength and Endurance
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- University of Patras
Chronic Heart Failure
Acupuncture on Cardiac and Autonomic Function in Human Heart Failure
Acupuncture treatment may improve the cardiac function and the quality of life in heart failure patients. These effects may be related to the inhibition of sympathetic activity and/or increased vagal function.
- Trial name
- NCT01804816
- Testing
- Acupuncture, No Intervention
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The Cleveland Clinic
Lymphoma, Sarcoma
WATCH (Wearable Artificial inTelligence for Cardiac Function and Health Monitoring)
The purpose of this study is to find a cost effective cardiovascular (CV) surveillance of cancer survivors over long periods of time to prevent the risk of progression of heart failure (HF) and related morbidity and mortality.
- Trial name
- NCT07058064
- Testing
- Electrocardiogram, Echocardiogram, LVEF echocardiogram
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Mayo Clinic
Any Patient Who Fulfills the Inclusion Criteria to be Implanted With a Dual Chamber Pacemaker Maybe Included in the Study as Per ACC/AHA Guidelines
Comparison of AAIsafeR and DDD Modes in Non-selected Patients
1 Purpose In patients with sinus node dysfunction (SND), the use of AAI mode is rare. In paroxysmal high-degree or complete atrio-ventricular (AV) block, paroxysmal vagally-mediated bradycardia, single chamber atrial pacemakers…
- Trial name
- CAN-SAVE R (NCT01219621)
- Testing
- Symphony Dual Chamber Rate Responsive Device
- Where
- 10 sites in Canada
- Volunteers
- 450 people
- Sponsor
- Sorin Group Canada
Obesity
Effect on Energy Metabolism at Cellular Level of Diet Plus Treatment With Ephedrine and Caffeine in Obesity
Brief Summary This trial was part of a sub-project targeted to diet, thermogenesis and obesity of a larger multicentre study named "Interaction between nutritional, social-behavioral and metabolic factors for prevention of…
- Trial name
- NCT02048215
- Testing
- Caffeine, Ephedrine, Hypocaloric diet
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Istituto Auxologico Italiano
Heart Failure, Congestive, Renal Insufficiency
Effect of KW-3902IV in Combination With IV Furosemide on Renal Function in Subjects With CHF and Renal Impairment
The purpose of this study is to characterize the safety and tolerability of KW-3902IV and measure its effect on renal function.
- Trial name
- NCT00159614
- Testing
- KW-3902IV
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- NovaCardia, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Coronary Heart Disease
Influencing Factors of the Diagnostic Accuracy of Novel Coronary Functional Evaluation Methods
In this study, patients were retrospectively included, univariate and multivariate analysis of factors affecting their diagnosis inconsistencies was performed, and a new diagnostic model was constructed by logistic regression.
- Trial name
- NCT06178133
- Volunteers
- 500 people
- Sponsor
- Peking University Third Hospital
Coronary Artery Disease
A Randomized Controlled Trial in Women With Coronary Artery Disease Investigating the Effects of Aerobic Interval Training Versus Moderate Intensity Continuous Exercise
Heart disease is the number one killer amongst chronic diseases around the world, and it is responsible for taking the lives of an estimated 17.5 million people each year.
- Trial name
- CAT vs MICE (NCT02966158)
- Testing
- AIT Group
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- University Health Network, Toronto
Sport, Muscle Fatigue
Effect of KA-EX Supplementation on Recovery Parameters in High-Level Young Football Players
The purpose of this study is to evaluate the effects of KA-EX supplementation on recovery parameters in elite young football players.
- Conditions
- Sport, Muscle Fatigue, Recovery of Function (G11.427.698.620), Athletic Performance
- Trial name
- Effect of KA-E (NCT07824752)
- Testing
- KA-EX, Experimental: KA-EX Supplement
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Antonio Molina Lopez
Coronary Artery Disease, Postoperative Care
CABG-AI-Supported Discharge Education
This randomized controlled trial will evaluate the effectiveness of artificial intelligence-supported individualized discharge education for patients undergoing coronary artery bypass graft (CABG) surgery.
- Conditions
- Coronary Artery Disease, Postoperative Care, Patient Discharge, Recovery of Function
- Trial name
- AI-D-E-CABG (NCT07503678)
- Testing
- AI-Supported Individualized Discharge Education, Standard Discharge Education
- Volunteers
- 128 people
- Sponsor
- Hasan Kalyoncu University