Clinical trials: Functional Chest Pain
Adhesive Capsulitis
Additional Effects of Thoracic Spine Mobilization Combined With Glenohumeral Joint Mobilization on Pain, Range of Motion, and Functional Disability in Adhesive Capsulitis
Adhesive capsulitis is a debilitating shoulder condition characterized by pain, restricted range of motion (ROM), and significant functional limitations.
- Trial name
- NCT07328295
- Testing
- Thoracic spine mobilization with Glenohumeral joint mobilization, Glenohumeral joint mobilization only
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Foundation University Islamabad
Angina Pectoris, Stable
Effects of Ivabradine on Residual Myocardial Ischemia After PCI
This is a randomized pharmacological study evaluating the effects of ivabradine in patients with residual angina after PCI. The role of ivabradine in patients with angina, without systolic dysfunction, is not yet clear.
- Trial name
- NCT03866395
- Testing
- Ivabradine
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Azienda Policlinico Umberto I
Observational
Use of FFR-CT in Stable Intermediate Chest Pain Patients With Severe Coronary Calcium Score
A prospective, blinded multicenter study for evaluation of chest pain patients with severe coronary calcium (Agatston score > 399).
- Trial name
- FACC (NCT03548753)
- Where
- Denmark
- Volunteers
- 278 people
- Sponsor
- Odense University Hospital
Angina Pectoris, Diabetes Mellitus, Type 2
Study Protocol for Rosiglitazone Versus Gliclazide in Diabetics With Angina
The principle objective of the trial is to compare rosiglitazone to gliclazide in patients with type 2 diabetes mellitus and chronic stable angina to see how the subjects' angina status changes.
- Trial name
- NCT00225342
- Testing
- Rosiglitazone, Gliclazide (Comparison drug)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Glasgow
Pain, Acute, Surgery
ESP Block in VATS: Programmed Intermittent Bolus Versus Continuous Infusion on Quality of Recovery
Fascial plane blocks, such as ESP, rely on the spread of local anaesthetic on an interfacial plane, automated boluses may be particularly useful for this group of blocks.
- Trial name
- NCT05181371
- Testing
- Ultrasound Guided ESP Block with Programmed Intermittent Bolus (PIB) for VATS, Ultrasound Guided ESP Block with Continuous Infusion (CI) for VATS
- Where
- 2 sites in Ireland
- Volunteers
- 60 people
- Sponsor
- Mater Misericordiae University Hospital
Acute Coronary Syndrome, Myocardial Infarction (MI)
Clinical Echocardiography and S' Wave for Early Recognition of Acute Coronary Syndrome in the Emergency Department, A Prospective Study
The goal of this prospective observational study is to assess the diagnostic accuracy of the tissue Doppler imaging (TDI) S' wave in detecting acute coronary syndrome (ACS) in adult patients presenting to the emergency department…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction (MI), Non-ST Elevation Myocardial Infarction, Unstable Angina
- Trial name
- CLEAR_ECHO (NCT06860997)
- Testing
- Tissue Doppler Imaging (TDI) S' Wave Echocardiography
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Subacromial Impingement Syndrome, Exercise Addiction
Effects of Exercise or Taping on Pain, Function, Range of Motion, Strength and Kyphosis in Subacromial Pain Syndrome
Participants with subacromial pain syndrome underwent shoulder exercises. In addition to the exercises, group A received thoracic extension exercise and group B received kinesio taping.
- Conditions
- Subacromial Impingement Syndrome, Exercise Addiction, Shoulder Pain
- Trial name
- NCT06777121
- Testing
- Shoulder exercises + Thoracic extension exercise, Shoulder exercises + Thoracic kinesio taping, Shoulder exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sevtap Günay
Cystic Fibrosis
Do Physiotherapy Techniques Improve Posture During Admission for a Chest Infection in Adults With Cystic Fibrosis?
Hypothesis: The addition of a series of musculoskeletal techniques to normal optimal care for the treatment of a respiratory exacerbation in inpatient adults with cystic fibrosis, will lead to further improvements in pain…
- Trial name
- NCT00806884
- Testing
- Physiotherapy Musculoskeletal Treatment, Control group measurements
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Pain, Decreased Lung Function
ThOracoscopic Wedge Resection Treated With Chest Tube Removal Intraoperatively
Chest tubes are used routinely although preliminary studies demonstrate the feasibility and safety of intraoperative chest drain removal. Previous studies are however either retrospective or mainly concerning benign disease.
- Conditions
- Pain, Decreased Lung Function, Delayed Discharge
- Trial name
- TOTTI (NCT02829736)
- Testing
- Intraoperative sealing test, Standard post-operative chest tube, Intraoperative chest tube removal
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Thoracic Outlet Syndrome
Effect of Low-Power Laser Therapy on Pain and Functional Outcomes in Patients With Thoracic Outlet Syndrome
The purpose of this study is to evaluate the effect of low-power laser therapy on pain intensity and functional outcomes in patients diagnosed with Thoracic Outlet Syndrome (TOS).
- Trial name
- LPLT-TOS (NCT07535853)
- Testing
- Low level laser therapy, Therapeutic Ultrasound, Physical Therapy Exercises
- Volunteers
- 40 people
- Sponsor
- Cairo University
Angina, Coronary Artery Disease
Exercise-training Before Coronary Artery Bypass Graft (CABG)
The aim is to evaluate the effect of exercise training upon endothelial function in the mammary artery of patients who are scheduled for CABG, as well as study the functional properties of single cells isolated from a small…
- Trial name
- NCT00218985
- Testing
- Exercise training
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Chest Pain, Pneumonia
The Effect of Exercise on Physical Function and Health in Older People After Discharge From Hospital
The aim of this study is to investigate the effect of a multi-component exercise program on physical function, physical activity and health-related quality of life (HRQOL) in older people recently discharged from hospital.
- Conditions
- Chest Pain, Pneumonia, Transient Ischemic Attack, Stroke
- Trial name
- OLPADIS (NCT02905383)
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Coronary Artery Disease, Stable Angina
Functional Assessment of Myocardial Ischemia by Intracoronary Electrocardiogram
In patients with chronic stable coronary artery disease (CAD), percutaneous coronary intervention (PCI) targets hemodynamically significant coronary lesions, i.e., those thought to cause inducible ischemia.
- Conditions
- Coronary Artery Disease, Stable Angina, Coronary Artery Stenosis, Ischemia
- Trial name
- FFRicECG (NCT03985241)
- Testing
- Functional Assessment of Myocardial Ischemia by icECG
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Thoracic Anesthesia, Geriatric Anesthesia
The Effect of Single Lung Ventilation Duration and Intraoperative Brain Oxygenation on Cognitive Function and Postoperative Pain in Geriatric Patients
One lung ventilation (OLV) is commonly used in thoracic surgery. Although the lack of ventilation of the lung in the surgical area (independent lung) during OLV redirects pulmonary blood flow to the dependent lung, shunt…
- Conditions
- Thoracic Anesthesia, Geriatric Anesthesia, One Lung Ventillation (OLV), POCD - Postoperative Cognitive Dysfunction
- Trial name
- NCT07339124
- Testing
- Cognitive Remediation, Pain Medicine
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Neck Pain
Effect of Manual Therapy on Non Specific Neck Pain
The aim of this study is to investigate the effects of Mulligan concept Reverse Natural Apophysial Glide Technique (RNAGS)technique applied to the thoracic region on pain, limitation of movement, and functionality in individuals…
- Trial name
- NCT06200038
- Testing
- Mulligan Reverse Natural Apophysial Glide Technique (RNAGS), Conventional physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Abant Izzet Baysal University
Angina, Stable, Angina Pectoris, Variant
Coronary Microvascular Function and CT Coronary Angiography (CorCTCA)
Angina in patients without obstructive coronary artery disease (CAD) is a clinical conundrum and patient management is heterogeneous. Hypothesis: Abnormal coronary function is common and clinically relevant in this population.
- Conditions
- Angina, Stable, Angina Pectoris, Variant, Microvascular Angina
- Trial name
- CorCTCA (NCT03477890)
- Testing
- Stratified medicine involving a diagnostic intervention
- Where
- 3 sites in United Kingdom
- Volunteers
- 250 people
- Sponsor
- NHS National Waiting Times Centre Board
Angina Pectoris, Myocardial Infarction
The Effect of Remote Ischemic Preconditioning on Major Organ Function in Patients With Coronary Artery Disease Undergoing Orthopedic Surgery
The investigators attempt to investigate the organ protective effect of remote ischemic conditioning in patients undergoing non-cardiac surgery with history of ischemic heart disease.
- Trial name
- RIPC-Angina (NCT02808936)
- Testing
- Remote ischemic preconditioning
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Pain, Postoperative, Cognitive Function Abnormal
Perioperative Cognitive Training in Thoracic Surgery
More than 30% of patients undergoing thoracic surgical procedures develop persistent post-surgical pain (PPSP), which results in impaired functioning, diminished quality of life, and increased risk of chronic opioid use.
- Conditions
- Pain, Postoperative, Cognitive Function Abnormal, Lung Cancer
- Trial name
- COFLEX-T (NCT04563234)
- Testing
- COFLEX neurocognitive training, Crossword puzzles
- Sponsor
- Washington University School of Medicine
Breast Cancer, Cognitive/Functional Effects
Study of Symptoms Caused by Cancer and Cancer Therapy in Patients With Invasive Breast, Lung, Prostate, or Colorectal Cancer
RATIONALE: Questionnaires that assess symptoms caused by cancer and cancer therapy may help improve the ability to plan treatment for patients with invasive cancer to help them live longer and more comfortably.
- Conditions
- Breast Cancer, Cognitive/Functional Effects, Colorectal Cancer, Lung Cancer
- Trial name
- NCT00303914
- Testing
- assessment of therapy complications, cognitive assessment, psychosocial assessment and care
- Where
- 32 sites in United States
- Volunteers
- 2,310 people
- Sponsor
- Eastern Cooperative Oncology Group
Coronary Artery Disease, Myocardial Ischemia
The FAVOR II China Study
Quantitative Flow Ratio (QFR) is a novel method for evaluating the functional significance of coronary stenosis. The purpose of the FAVOR II China study is to evaluate the diagnostic accuracy of on-line QFR with FFR as the…
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Cardiovascular Diseases, Arteriosclerosis
- Trial name
- NCT03191708
- Testing
- Fractional Flow Reserve (FFR)
- Where
- 5 sites in China
- Volunteers
- 308 people
- Sponsor
- China National Center for Cardiovascular Diseases