Clinical trials: Functional Cognitive Disorder
Irritable Bowel Syndrome
Internet-delivered CBT for Irritable Bowel Syndrome
The aim of this study is to investigate the efficacy of a 10 week Internet-delivered CBT treatment for patients diagnosed with IBS. The patients' work with the treatment and is supported through online contact with a therapist.
- Trial name
- NCT01171053
- Testing
- Internet-delivered CBT, Therapist support
- Where
- Sweden
- Volunteers
- 86 people
- Sponsor
- Karolinska Institutet
Alzheimer Disease
A Donanemab (LY3002813) Study in Participants With Preclinical Alzheimer's Disease (TRAILBLAZER-ALZ 3)
The main purpose of this study is to evaluate the safety and efficacy of donanemab in participants with preclinical Alzheimer's Disease (AD) over up to 332 weeks.
- Trial name
- NCT05026866
- Testing
- Donanemab
- Where
- 216 sites in United States, Japan and 1 more
- Volunteers
- 2,996 people
- Sponsor
- Eli Lilly and Company
Type 2 Diabetes
The Effects of Specialty Coffee on Cognitive Function in People With Type 2 Diabetes
Coffee has been found to have beneficial effects on cognitive function and blood sugar control. Benefits include reduced risk of cognitive decline and improved performance on cognitive tests, as well as reduced risk of diabetes…
- Trial name
- NCT05709847
- Testing
- Coffee
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Reading
Advanced ALK/ROS1-positive NSCLC, Carcinoma, Non-Small-Cell Lung (NSCLC)
Vortioxetine for Cognitive Function in ALK-positive NSCLC Treated With Lorlatinib
This observational study evaluates whether vortioxetine - an antidepressant medication with cognitive-enhancing properties - can reduce the neurological and cognitive side effects associated with lorlatinib treatment in patients…
- Conditions
- Advanced ALK/ROS1-positive NSCLC, Carcinoma, Non-Small-Cell Lung (NSCLC), Lung Adenocarcinoma, ALK-positive Non-small Cell Lung Cancer (NSCLC)
- Trial name
- NCT07633626
- Where
- Colombia
- Volunteers
- 24 people
- Sponsor
- Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo
Mild Cognitive Impairment
Feasibility Study of Virtual Sail 3D in Cognitive Functions
This research project will assess the feasibility and preliminary effectiveness of a 6-week intervention to improve cognitive functions using the 3D immersive virtual reality software "CEREBRUM" with virtual sailing scenarios…
- Trial name
- NCT06579378
- Testing
- VSail 3D, WEB-Health
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Cagliari
Cognitive Symptom, Pre Senile Dementia
Compensatory Training to Support Brain Healthy Lifestyle Changes in Those at Risk for Alzheimer's Disease
The Researchers are trying to better understand if behavioral interventions can help improve memory compensation and engagement in healthy lifestyle behaviors in those with memory concerns but normal mental status exam.
- Conditions
- Cognitive Symptom, Pre Senile Dementia, Alzheimer Disease
- Trial name
- NCT04118985
- Testing
- Cognitive rehabilitation and health behavior change intervention, Self-implementation
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Mild Traumatic Brain Injury, Cognitive Impairment
The Effect of Cognitive Rehabilitation Therapy in Improving Cognitive Function of Attention Following Mild Traumatic Brain Injury
This research is a randomised controlled study. The study hypothesis is cognitive rehabilitation for attention deficits following mild traumatic brain injury will improve patient's cognitive outcome, measured by…
- Trial name
- NCT03237676
- Testing
- Structured cognitive rehabilitation therapy, Patient-centred cognitive therapy
- Where
- Malaysia
- Volunteers
- 90 people
- Sponsor
- University of Malaya
Multiple Sclerosis
Cannabis (THC vs. CBD) in Multiple Sclerosis
The goal of this clinical trial is to examine the effect of Cannabis components, THC and CBD, on cognition and bladder symptoms in people with Multiple Sclerosis (MS).
- Trial name
- NCT06261489
- Testing
- THC, CBD
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Marijuana Dependence
Sex Differences in Attentional Bias in Marijuana-dependent Individuals
The purpose of this study is to explore sex differences in cognitive functioning and responses to marijuana-related items, and to determine whether stress impacts these measures.
- Trial name
- NCT01179425
- Testing
- Cognitive stressor
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Colorectal Cancer, Older Adults (60 - 85 Years Old)
Chemo Brain Prehab Project
Colorectal cancer is 37% higher in the North West than the national average and is treated by chemotherapy, including fluorouracil, capecitabine, and oxaliplatin.
- Conditions
- Colorectal Cancer, Older Adults (60 - 85 Years Old), Physically Inactive, Chemotherapy
- Trial name
- CHEMOBRAIN (NCT07341217)
- Testing
- Exercise Prehabilitation, Multivitamins, Standard Care (in control arm)
- Where
- 4 sites in United Kingdom
- Volunteers
- 86 people
- Sponsor
- Dr. Chris Gaffney
Neurologic Diseases, Arthropathy of Knee
Experience of Use and Biopsychosocial Effects of Robotic and Virtual Reality Devices in Neuromotor Rehabilitation
The implementation of virtual reality (VR) and robotic devices in neuromotor rehabilitation has so far provided promising evidence in terms of efficacy throughout different clinical populations.
- Conditions
- Neurologic Diseases, Arthropathy of Knee, Arthropathy of Hip
- Trial name
- NCT05399043
- Testing
- Multidisciplinary Conventional Neuromotor Rehabilitation, Technology-based Rehabilitation
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Cognitive Dysfunction, Mild Cognitive Impairment
Effect of Dual Task Exercise on Cognitive and Physical Function in the Elderly With Mild Cognitive Impairment
The purpose of this study is to investigate the effect of the dual task exercise program on cognitive and physical function in the elderly with mild cognitive impairment.
- Trial name
- NCT05855785
- Testing
- dual task exercise, home exercise
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Seoul National University Boramae Hospital
Apnea, Sleep
Effects of CPAP on Cognitive Function, Neurocognitive Architecture and Function in Patients With OSA: The SMOSAT Trial
Multiple clinical studies have indicated that obstructive sleep apnea (OSA), the most common chronic sleep disorder, may affect neurocognitive function, and that treatment for continuous positive airway pressure (CPAP) has some…
- Trial name
- NCT02886156
- Testing
- CPAP, BSC
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
MRI, Functional, Carotid Artery Stenosis
Cognitive Function and Brain Connectivity in CAS Patients:a Rs-fMRI Study
This is a prospective study aimed to explore the changes of cognitive function after surgery for CAS and the correlation with brain connectivity, in order to look for the clinical biomarkers to predict the carotid stent…
- Trial name
- NCT05292729
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Metastatic Brain Tumor, Cerebral Metastases
Impact of Cognitive Rehab and Physical Activity on Cognition in Patients With Metastatic Brain Tumors Undergoing RT
To determine the feasibility of processes and instruments with an overarching purpose to guide the design of a larger study. To determine the feasibility of individuals with metastatic brain tumor(s) to engage in physical…
- Trial name
- NCT03096431
- Testing
- Physical Activity, Cognitive rehabilitation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Virginia Commonwealth University
Cognitive Impairments, Schizophrenia
Effects of Transcranial Direct Current Stimulation on Cognitive Rehabilitation in Schizophrenia
The aim of this prospective, randomized, double-blind, placebo-controlled study is to assess whether transcranial direct current stimulation (tDCS) applied prior to RehaCom cognitive training can improve cognitive functioning in…
- Trial name
- NCT07273175
- Testing
- active tDCS
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Lodz
Multiple Sclerosis
Intensity Depended Impacts on Cognitive Functions in Persons With Multiple Sclerosis - a Pilot Study
Multiple Sclerosis (MS) is a chronic autoimmune disease where lymphocytes inflict damage to the axons and myelin sheaths of the central nervous system.
- Trial name
- NCT02408367
- Testing
- Exercise, Relaxation
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Jens Bansi
Mild Cognitive Impairment (MCI)
Gamma tACS to Improve Cognitive Function in Mild Cognitive Impairment
Mild cognitive impairment (MCI) is a decline in memory and thinking that exceeds normal aging but does not substantially disrupt daily life, and it raises the risk of developing dementia.
- Trial name
- TACS-MCI (NCT07752316)
- Testing
- transcranial electrical stimulation
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Obesity
Combined Physical-cognitive Exercise and Dietary Intervention for Postmenopausal Obese Women
This study aims to examine the effects of dietary intervention combined with physical-cognitive exergaming on cognitive performance and circulating biomarkers of obese postmenopausal women.
- Trial name
- NCT04768725
- Testing
- Dietary intervention combined with physical-cognitive exergaming, Dietary intervention, Physical-cognitive intervention
- Where
- Thailand
- Volunteers
- 92 people
- Sponsor
- Chiang Mai University
Obesity
Executive Function Training in Childhood Obesity: Food Choice, Quality of Life and Brain Connectivity
This study evaluates if executive function training in obese children can improve food-related choices and produce cognitive and neuroimaging changes, but also improve psychological and physical status and quality of life…
- Trial name
- TOuCH (NCT03615274)
- Testing
- Executive function training, Psychoeducation
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- University of Barcelona
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