Clinical trials: Functional Cognitive Disorder
Alzheimer
Telerehabilitation in Alzheimer's Disease
Telemedicine has developed rapidly during the COVID-19 pandemic and is now integrated into the clinical practice of many hospitals.
- Trial name
- VRTAD (NCT07722169)
- Testing
- Online cognitive telerehabilitation, VRRS tablet
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Schizophrenia, Schizoaffective Disorder
Cognitive Therapy for Negative Symptoms and Functioning
This clinical trial tests the effectiveness of cognitive therapy (CT) to improve outcomes in outpatients diagnosed with schizophrenia or schizoaffective disorder who manifest prominent negative symptoms.
- Trial name
- NCT00350883
- Testing
- Cognitive Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Pennsylvania
Cocaine Use, Cocaine Dependence
rTMS and Cognitive-behavioral Therapy for Cocaine Use Disorder
The goal of the study is to investigate the feasibility, safety, and effect of rTMS on mPFC/dACC activity using a combination of fMRI and clinical outcome measures, when used as an augmentation to CBT.
- Conditions
- Cocaine Use, Cocaine Dependence, Cocaine Use Disorder, Cocaine Use Disorder, Moderate
- Trial name
- COAST (NCT05974202)
- Testing
- Active H7-coil repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- New York State Psychiatric Institute
Type 2 Diabetes Mellitus
The Effect of Metformin and DPP4 Inhibitors on Cognition and Cardiovascular Protection in Type 2 Diabetic Patients
The Impact of Metformin and Dipeptidyl Peptidase- 4 Inhibitors on Cognitive Function and cardiovascular protection in Type 2 Diabetic Patients
- Trial name
- NCT05429554
- Testing
- Vildagliptin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- MTI University
Irritable Bowel Syndrome
Cognitive Behavior Therapy (CBT) Compared to Stress Management for Irritable Bowel Syndrome
The study aims to compare two manualized treatments. They are based on cognitive behavior therapy or stress management. Both treatments are delivered via an internet application and the patients' work with the treatments is…
- Trial name
- NCT01051973
- Testing
- Cognitive behavior therapy, Stress management
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Sleep Quality, Cognitive Functions
Sleep Quality and Cognitive Functions in Adults: A Cross-Sectional Study
This observational cross-sectional study aims to examine the association between sleep quality and cognitive functions in healthy young adults.
- Trial name
- NCT07387783
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Alzheimer's Disease, Mild Cognitive Impairment
A Composite MR Neuroimaging Marker for Alzheimer's Disease
The purpose of this study is to use a functional MRI (fMRI) index to compare the brain activity of healthy volunteers to that of people with mild cognitive impairment (MCI) and Alzheimer's disease.
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Frontotemporal Dementia
- Trial name
- NCT01615666
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Chronic Schizophrenia
Cognitive Remediation and Sheltered Employment in Schizophrenia
This study, driven on schizophrenic patients, is aimed at : 1. Measuring the efficiency of the cognitive remediation program RECOS (COgnitive REmediation in Schizophrenia) on the capacity of the patients suffering from…
- Trial name
- RemedRehab (NCT01891929)
- Testing
- RECOS (COgnitive REmediation for Schizophrenia), TAU (Treatment As Usual)
- Where
- 13 sites in France
- Volunteers
- 79 people
- Sponsor
- Hôpital le Vinatier
Intracranial Lymphatic Circulation Disorder, Alzheimer's Disease
Effect of Cervical Lymphaticovenous and Lymph Node-to-Vein Anastomosis in Patients With Intracranial Lymphatic Circulation Disorder
This study is a single-center, prospective clinical trial designed to evaluate the therapeutic effects of lymphaticovenular anastomosis (LVA) and lymph node-venous anastomosis (LNVA) in patients with intracranial lymphatic…
- Trial name
- CLVA-CLNA-ICLC (NCT07328386)
- Testing
- Cervical Lymphaticovenous and Lymph Node-to-Vein Anastomosis
- Where
- South Korea
- Volunteers
- 114 people
- Sponsor
- Hong Joonpio
Breast Cancer, Cognitive/Functional Effects
Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
RATIONALE: Stereotactic radiation therapy can send x-rays directly to the tumor and cause less damage to normal tissue. Radiation therapy uses high-energy x-rays to kill tumor cells.
- Conditions
- Breast Cancer, Cognitive/Functional Effects, Lung Cancer, Metastatic Cancer
- Trial name
- NCT00377156
- Testing
- radiation therapy, stereotactic radiosurgery
- Where
- 64 sites in United States, Canada
- Volunteers
- 213 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Physiologic Monitoring, Self-report Questionnaire
Can the Belgian Coastal Environment Improve Physical and Cognitive Health in Older Adults?
The goal of this interventional study is to learn if exposure to coastal environments improves the physical and cognitive health of older adults over the age of 60.
- Conditions
- Physiologic Monitoring, Self-report Questionnaire, Sleep Quality, Cognitive Function
- Trial name
- NCT06893224
- Testing
- Coastal exposure, Urban exposure
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Ghent
Autism
Treatment for Children With Autism and Anxiety
Children with high-functioning autism spectrum disorders (ASD) are at high risk for developing significant anxiety symptoms. Cognitive behavior therapies (CBT) are frequently used for children with anxiety symptoms with good…
- Trial name
- NCT01727466
- Testing
- Facing Your Fears
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Major Depression
Inflammatory Markers and Cognitive Function in Major Depression
Major depression is accompanied by cognitive changes as well as alterations in multiple physical functions. The inflammatory system is altered generally toward a pro-inflammatory state.
- Trial name
- NCT01391221
- Testing
- Duloxetine
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal
Binge Drinking
Combining Cognitive Training With tDCS to Enhance Memory Inhibition in Young Binge Drinkers
This study protocol aims to examine the behavioral and electroencephalographic (EEG) correlates of memory inhibition (MI) among college binge drinkers (BDs).
- Trial name
- NCT05237414
- Testing
- Active tDCS, Active CT
- Where
- Portugal
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Minho
Major Depressive Disorder, Post-traumatic Stress Disorder
Cognitive Training Program for Individuals With Depression and Post-Traumatic Stress Disorder
Individuals with affective disorders (including post-traumatic stress disorder (PTSD) and major depressive disorder (MDD)) often experience declines in cognitive abilities such as memory and attention.
- Trial name
- NCT02502604
- Testing
- Goal Management Training
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Breast Cancer
Exercise Program in Cancer and Cognition
This randomized control trial will examine whether a well-controlled and monitored exercise intervention improves cognitive function in postmenopausal women with early-stage breast cancer and will explore whether neuroimaging…
- Trial name
- EPICC (NCT02793921)
- Testing
- Moderate-Intensity Aerobic Exercise Intervention
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- University of Pittsburgh
Alcohol Dependence
Effect of Anti-craving Medication on Cognitive Functions in Alcohol Dependence: an ERP Study
The main aim of this research is to investigate whether the use of cognitive event-related potentials is an interesting way to identify subgroups of alcoholic patients displaying specific clinical symptoms and cognitive…
- Trial name
- NCT02107352
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Brugmann University Hospital
Alzheimer's Disease
Efficacy, Safety and Response Predictors of Astragalus Membranaceus on the Improvement of Cognitive Function in Mild-to-Moderate Alzheimer's Disease
Alzheimer's disease (AD), the most common cause of dementia, is characterized by cognitive impairment, mental and behavioural abnormalities, and social dysfunction.
- Trial name
- NCT05578443
- Testing
- 10g Astragalus, Routine treatment, 20g Astragalus
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Fujian Medical University Union Hospital
Chronic Pain, Opioid Use
Cognitive Function and Addiction Under Opioid Tapering
This study evaluates the effects of opioid dose reduction in the treatment of chronic pain in adults. Participants were divided in two groups: 1) patients that reduced opioid dose and 2) patients that kept the same opioid dose…
- Trial name
- NCT03365817
- Testing
- Opioids taper off, Opioid stable treatment
- Volunteers
- 75 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Heart Failure, Sleep Quality
Association Between Sleep Quality and Self-Care in Heart Failure Patients
The research will be conducted as a prospective and relational study to longitudinally investigate the effect of sleep quality on self-care in patients with heart failure (HF) and to evaluate the relationship between self-care…
- Conditions
- Heart Failure, Sleep Quality, Self Care, Cognitive Function
- Trial name
- NCT06747689
- Where
- Turkey (Türkiye)
- Volunteers
- 207 people
- Sponsor
- Dokuz Eylul University
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