Clinical trials: Functional Cognitive Disorder
Healthy Individuals
Study for Cognitive and Genetic Characterization of a 45-65 Years Old Population
Before Alzheimer's disease (AD) clinical symptoms appear, there is a long period when changes in the brain occur. In this long asymptomatic period or preclinical phase, studies with populations at risk of developing AD have shown…
- Trial name
- NCT01835717
- Where
- Spain
- Volunteers
- 2,743 people, healthy volunteers welcome
- Sponsor
- Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Other Functional Disturbances Following Cardiac Surgery, Memory Disorders
COGNITIVE - Cognitive Function After Sevoflurane or Propofol Anesthesia for Open-heart Operations
The aim of the study is to prove whether general anesthesia with inhaled sevoflurane reduces the frequency of neurological and cognitive impairment after open-heart operations with use of cardiopulmonary by-pass (CPB) in…
- Trial name
- NCT00541918
- Testing
- Diprivan (propofol, Astra Zeneca), Sevorane (sevoflurane, Abbott)
- Where
- 2 sites in Poland
- Sponsor
- Medical University of Gdansk
Sleep, Cognitive Impairment
Observational Study About Sleep Quality and Its Impact on Daily Life of Nursing-home Residents
Introduction: Poor sleep quality is common in most older adults. Because of the progressive aging of the population in Spain, there are more and more nursing-home and day centers, which give care to older adults.
- Conditions
- Sleep, Cognitive Impairment, Quality of Life, Age Problem
- Trial name
- NCT04592796
- Testing
- Xiaomi MiBand2, Socio-demographic questionnaire, EuroQol-5D-5L
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- Universidade da Coruña
Subjective Cognitive Decline (SCD)
Polyamine-enriched Diet in Elderly Individuals With Subjective Cognitive Decline
The overall objective of this study is to examine the effect of polyamine supplementation on cognitive performance and further characterization of individuals with subjective cognitive decline.
- Trial name
- SmartAge (NCT03094546)
- Testing
- Polyamine
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Supplement, Cognition Disorders in Old Age
Erinacine A-enriched Hericium Erinaceus Mycelia for Improvement of Recognition, Vision, and Functional MRI Alterations
This study was designed as randomized double blind placebo study to investigate the efficacy of Erinacine A-enriched Hericium erinaceus mycelia for improvement of recognition, vision, and functional MRI alterations.
- Conditions
- Supplement, Cognition Disorders in Old Age, Vision, fMRI
- Trial name
- NCT04065061
- Testing
- Erinacine A-enriched Hericium Erinaceus Mycelia
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- Chung Shan Medical University
Substance Abuse, Substance Dependence
fMRI Study of a Dual Process Treatment Protocol With Substance Dependent Adults
The purpose of this study is to determine whether drug-dependent adults who participate in a dual processing relapse prevention treatment protocol that allows for sensory-based exposure experiences over 10-weeks in outpatient…
- Conditions
- Substance Abuse, Substance Dependence, Alcohol Abuse, Drug Use
- Trial name
- NCT01320748
- Testing
- Dual Processing, Relapse Prevention
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- Inova Health Care Services
Cognitive Impairment, Cardiac Disease
Cognitive Function in Adults With Cardiac Disease
The purpose of this study is to identify cardiac patients' degree of unappreciated mild impairment in cognitive function patterns of cognitive function, and influencing factors related to cognitive functioning during…
- Trial name
- TimePoints (NCT01043315)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University Hospitals Cleveland Medical Center
General Health and Wellness, Energy and Vitality
M4C Nutraceutical Intervention Human Health Effects Pilot
This 3 month pilot study will be an unblinded, convenience sampling, nutraceutical intervention trial. Twenty fasted subjects will undergo a baseline health assessment via a questionnaire, baseline clinical chemistries, blood…
- Conditions
- General Health and Wellness, Energy and Vitality, Cognitive Function and Mental Health, Weight Management
- Trial name
- M4C Pilot (NCT06476236)
- Testing
- M4C
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Concordia University Wisconsin
Mild Cognitive Impairment
Effects of Bidomain Cognitive and Aerobic Training on Cognitive Functioning in Mild Cognitive Impairment.
The study aims to assess the effects of Bidomain cognitive and aerobic training on both cognitive functioning and quality of life in individuals with mild cognitive impairment.
- Trial name
- NCT06867016
- Testing
- Combined Cognitive & Aerobics Training, Cognitive Training
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Schizophrenia
iTBS on Negative Symptoms and Cognitive Function in Schizophrenia
The negative symptoms and cognitive deficits are common in patients with schizophrenia, and do not respond well to antipsychotics. The effective treatments for negative symptoms and cognitive impairment are still to be explored.
- Trial name
- NCT05137158
- Testing
- Intermittent theta burst stimulation
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Central South University
Mild Cognitive Impairment
Effectiveness of Tongue Resistance Exercises on Tongue and Swallowing Function in Frail Older Adults With MCI
The purpose of this study is to explore the effects of tongue resistance exercises on tongue muscle strength and swallowing function in frail older adults with mild cognitive impairment living in the community.
- Trial name
- NCT06766487
- Testing
- Tongue resistance exercises, cheek bulging exercises
- Where
- Taiwan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Chang Gung Medical Foundation
Mild Traumatic Brain Injury
Symptom-Targeted Rehabilitation for Concussion
The investigators are comparing two methods for helping improve everyday cognitive functioning in Canadian Armed Forces (CAF) veterans who have sustained a mild traumatic brain injury (mTBI).
- Trial name
- STAR-C2 (NCT05520710)
- Testing
- Cognitive Rehabilitation, Education
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- McMaster University
Atrial Fibrillation, Neuropsychology
Silent Cerebrovascular Lesion and Cognitive Decline Prevention by Cholesterol Lowering in Elderly AF Patients
In elderly patients with atrial fibrillation (AF) the presence of silent brain infarcts and neurocognitive deficit is high despite adequate treatment with oral anticoagulation.
- Conditions
- Atrial Fibrillation, Neuropsychology, Magnetic Resonance Imaging, Inflammation
- Trial name
- SPACE (NCT00449410)
- Testing
- Atorvastatin, ezetimibe
- Where
- Netherlands
- Volunteers
- 35 people
- Sponsor
- Radboud University Medical Center
Acute Stroke, Ischemic Stroke
Impact of Stroke Unit Care on Acute Stroke Outcomes
This observational study is designed to evaluate and compare the recovery outcomes of patients who have experienced their first acute stroke.
- Conditions
- Acute Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- NCT07750860
- Volunteers
- 140 people
- Sponsor
- Assiut University
Cognition Disorders in Old Age, Cognitive and Behavioral Impairment
Evaluation of the Effect of L-Arginine on the Cognitive Function in Geriatric Patients
This study aims to evaluate the effect of L-arginine supplementation on cognitive function in geriatric patients. Eligible participants will receive either L-arginine (6 grams once daily) or placebo, and their cognitive…
- Trial name
- NCT07338682
- Testing
- L-Arginine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- German University in Cairo
Colorectal Cancer, Cognitive Behavior Therapy
Cognitive Behavior Therapy (CBT) and Psychological Status and Immune Function
To explore the effect of CBT on psychological status of colorectal cancer patients undergoing chemotherapy. To explore the effect of CBT on immune function of colorectal cancer patients undergoing chemotherapy.
- Conditions
- Colorectal Cancer, Cognitive Behavior Therapy, Immune Function
- Trial name
- NCT04741308
- Testing
- cognitive behavior therapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai 10th People's Hospital
Alzheimer's Disease, Mild Cognitive Impairment
The Treatment of High Intensity Transcranial Current Stimulation for Alzheimer's Disease
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive cognitive dysfunction and behavioral impairment. It is currently the most common type of dementia in the old age.
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Dementia
- Trial name
- NCT06380725
- Testing
- Transcranial alternating current stimulation(real stimulation)
- Volunteers
- 60 people
- Sponsor
- Anhui Provincial Hospital
Concussion, Brain, Mild Traumatic Brain Injury
REhabilitation of MEMory Symptoms After BRain Concussion
Persistent memory symptoms after concussion are common, and likely perpetuated by unhelpful illness beliefs and coping behaviors.
- Trial name
- REMEMBR (NCT06956417)
- Testing
- Cognitive behavioral therapy, Cognitive rehabilitation
- Where
- 8 sites in Canada
- Volunteers
- 184 people
- Sponsor
- University of British Columbia
Ventricular Fibrillation, Ventricular Tachycardia
Investigation of Cognitive Function Before and After Induced Ventricular Fibrillation in Electrophysiological (EP) Study
In this study, changes in electroencephalogram (EEG) and the hemodynamic state during ventricular fibrillation or induced ventricular tachycardia are investigated.
- Trial name
- NCT00176176
- Testing
- EEG
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Heidelberg University
Cognition, Parkinson's Disease
Turkish Validation of the Parkinson Disease Cognitive Functional Rating Scale
The aim of the present study is to translate the Parkinson's Disease-Cognitive Functional Rating Scale into Turkish (PD-CFRS-Turkish version) and to evaluate its validity and reliability.
- Conditions
- Cognition, Parkinson's Disease, Reliability and Validity, Cognitive Functions
- Trial name
- NCT07253376
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gazi University
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