Clinical trials: Functional Cognitive Disorder
Primary Brain Tumour, Radiation Toxicity
Cognitive Function After Radiation Therapy for Primary Brain Tumours
This study will assess cognitive function in patients with a primary brain tumour treated with radiation therapy (RT) to generate radio-sensitivity and volume effect parameters for the development of cognitive dysfunction.
- Conditions
- Primary Brain Tumour, Radiation Toxicity, Cognitive Impairment
- Trial name
- NCT04306432
- Testing
- Cognitive tests and Patient Reported Outcomes
- Where
- 5 sites in Denmark
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Neurocognitive Dysfunction, Brain Metastases
CBF and NCF Changes With Brain Radiation
This study will be a dual-arm prospective longitudinal cohort study for patients with brain metastases, at least one of which is appropriate for radiotherapy, to explore brain and cognitive changes following SRS or WBRT and…
- Trial name
- NCT03606421
- Testing
- SRS and neurocognitive assessments, WBRT and neurocognitive assessments
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- University Health Network, Toronto
Cognitive Function Abnormal, Anesthesia
Perioperative Changes of Cerebrovascular Autoregulation and Association With Cognitive Function
Cerebral blood flow is tightly regulated to ensure constant cerebral perfusion independently from systemic blood pressure fluctuations.
- Conditions
- Cognitive Function Abnormal, Anesthesia, Surgery
- Trial name
- NCT04101006
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Stroke, Cognitive Impairment
Effects of Hyperbaric Oxygen Combined With Aerobic Exercise on Working Memory Among Stroke Patients
This single-center randomized controlled trial enrolled stroke patients with working memory impairment. Participants were randomly divided into the hyperbaric oxygen combined low-intensity focused ultrasound intervention group…
- Trial name
- NCT07772947
- Testing
- Conventional rehabilitation therapy, Moderate-intensity aerobic exercise, Hyperbaric Oxygen Therapy (HBOT)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sixth Hospital of Wuhan, Affiliated Hospital of Jianghan University
Sclerosis, Multiple
Gut Microbiota Composition, Cognitive Function, and Physical Fitness in Multiple Sclerosis Patients
The evidence suggests that multiple sclerosis (MS) induces a decline in motor and cognitive function and provokes a shift in gut microbiome composition in patients.
- Trial name
- MSDANCE (NCT06220409)
- Testing
- Dance classes
- Where
- Slovakia
- Volunteers
- 29 people
- Sponsor
- Comenius University
Stroke
Safety and Efficacy of Multisensory Stimulation Virtual Reality for Stroke Patients.
This was a single-blind randomized controlled trial of multisensory stimulation virtual reality to improve motor and cognitive dysfunction in stroke patients.
- Trial name
- NCT06275516
- Testing
- multi-sensory stimulation immersive VR+ treadmill training, treadmill training
- Where
- China
- Volunteers
- 40 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Chronic Stroke, Cognitive Impairment
pBFS-guided iTBS Over the Left DLPFC for Chronic PSCI
The study aims to investigate the efficacy and safety of intermittent theta burst stimulation (iTBS) guided by the personalized Brain Functional Sector (pBFS) technique in the treatment of patients with chronic post-stroke…
- Trial name
- NCT05953415
- Testing
- active iTBS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Changping Laboratory
Insomnia
Insomnia Treatment and EMA (Ecological Momentary Assessment) Outcomes
The goal of this study is to examine the impact of suvorexant, an FDA-approved insomnia medication, on daytime symptoms (as measured by the Daytime Insomnia Symptoms Scale: cognition, positive mood, negative mood, and…
- Trial name
- NCT05908526
- Testing
- Baseline surveys, Cognitive testing and EMAs, Actiwatch
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Maryland, Baltimore
Epilepsy, Cognitive Function 1, Social
The Effect of Dual Task on Postural Control in Children Diagnosed with Epilepsy
An individual's postural control is often accompanied by other tasks in daily life, such as cognitive tasks. Cognitive dual task (cognitive dual task) is the ability to perform two or more cognitive and motor activities…
- Conditions
- Epilepsy, Cognitive Function 1, Social, Balance; Distorted, Children
- Trial name
- NCT06529133
- Testing
- Evaluation of postural control
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Glucose Metabolism Disorders, Obesity
To Determine the Effect of GLP1 on Cognitive Function, Brain Glucose Metabolism and Neuroplasticity.
To test the hypothesis that GLP1 can exert favourable effects on multiple aspects of brain function. To this purpose, the investigator determine whether chronic increase in GLP1 concentration as it occurs after bariatric surgery…
- Conditions
- Glucose Metabolism Disorders, Obesity, Degenerative Brain Disorder
- Trial name
- NCT03414333
- Testing
- RYGB, GLP-1
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- University of Pisa
Alzheimer Disease
Effects of Dual-Task Training In Individuals With Alzheimer
The purpose of this study is to investigate the effects of dual-task training on balance, fear of falling, cognitive functions, dual-task performance, depression and quality of life in individuals with Alzheimer.
- Trial name
- NCT05765552
- Testing
- Dual-Task Training, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Ege University
Post-Stroke Cognitive Impairment (PSCI), Stroke
Artificial Intelligence-Based Cognitive Training in Patients With Stroke
This study would answer the following question:Does AI application-based training improve cognitive function in Patients with Stroke? The aims of this study: To investigate the efficacy of AI application-based training on…
- Conditions
- Post-Stroke Cognitive Impairment (PSCI), Stroke, Artifical Intelligence
- Trial name
- AICoRe-Stroke (NCT07452276)
- Testing
- cognifit Mobile Application for Cognitive Training, Conventional Cognitive Rehabilitation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Omima Alaa Eldin Hussein
Acquired Brain Injury, Development, Child
COgnitive REhabilitation in Pediatric Patients with ABI, from Vegetative State to Functional Recovery
Acquired brain injuries (ABI) represent one of the most important cause of disability and mortality during the pediatric age, also in the western Countries.
- Trial name
- COREABI (NCT04499092)
- Testing
- Personalized Neuropsychological treatment (CORE-ABI), Sequential Neuropsychological treatment (SET-ABI)
- Where
- Italy
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Type 1 Diabetes Mellitus, Hypoglycemia Unawareness
The Role of Endogenous Lactate in Brain Preservation and Counterregulatory Defenses Against Hypoglycemia
Iatrogenic hypoglycemia is the most frequent acute complication of insulin therapy in people with type 1 diabetes (T1DM). Recurrent hypoglycemic events initiate a process of habituation, characterized by suppression of…
- Trial name
- NCT02308293
- Testing
- High intensity exercise, Lay down comfortably
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Attention Deficit Hyperactivity Disorder
Standardized Lycium Chinense Fruit Extract Enhances Attention and Cognitive Function in Healthy Young People
Lycium chinense fruit (LCF) is widely distributed in East Asia that has been used traditionally for anti-aging purposes. This study was performed to examine the effects of LCF on attention and cognitive function in healthy young…
- Trial name
- NCT03439111
- Testing
- Standardized Lycium chinense Fruit Extract (LCF) capsules
- Where
- South Korea
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Biomix
Schizophrenia
C-Cog in Early Course Schizophrenia Study
The purpose of this study is to examine the role of clinical stability in functional recovery. in first episode schizophrenia.
- Trial name
- NCT05662306
- Testing
- Aripiprazole Lauroxil, Computerized cognitive and functional skills training
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Miami
Development Coordination Disorder, Motor Coordination or Function; Developmental Disorder
The Effects of Yoga on Sensory, Motor, Cognitive Skills, and Perceived Stress in Children With Developmental Coordination Disorder
This clinical study aims to investigate the effects of yoga on children with Developmental Coordination Disorder (DCD). DCD is a condition that can make it difficult for children to perform everyday activities, as it affects…
- Conditions
- Development Coordination Disorder, Motor Coordination or Function; Developmental Disorder, Sensory Integration Disorder, Perceived Stres Level
- Trial name
- NCT07547514
- Testing
- Yoga intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Fenerbahce University
Brain Tumors, Nervous System Tumors
Armodafinil in Treating Fatigue Caused By Radiation Therapy in Patients With Primary Brain Tumors
RATIONALE: Armodafinil may help relieve fatigue and improve quality of life in patients with cancer receiving radiation therapy to the brain.
- Conditions
- Brain Tumors, Nervous System Tumors, Cognition Disorders, Fatigue
- Trial name
- NCT01032200
- Testing
- Armodafinil
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Wake Forest University Health Sciences
Postoperative Cognitive Dysfunction
Feasibility Study of Preoperative Cognitive Training in Cardiac Surgical Patients
The purpose of this study is to evaluate the feasibility of administering a 20-day preoperative cognitive training intervention (Cog-Train) to a widely inclusive sample of cardiac surgical patients.
- Trial name
- Cog-Train (NCT02053207)
- Testing
- Cog-Train Intervention
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Cognitive Impairment, Mild, Executive Dysfunction
Does Computerized Cognitive Training Improve Executive Functioning in the Older Adult?
Explanation of the study: As the older adult population continues to rise, so will normal cognitive aging. This increase raises concern for maintaining cognitive function and possibly delaying the onset of disorders such as…
- Trial name
- CCT (NCT03170492)
- Testing
- RehaCom Computerized Cognitive Training for 480 minutes, Pencil-and-Paper Cognitive Training for 480 minutes
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of the Sciences in Philadelphia
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