Clinical trials: Functional Cognitive Disorder
Obesity, Bariatric Surgery Candidate
Effects of Change in Insulin Resistance and Systemic Inflammation on Brain Structure and Function
Obesity is associated with alterations in brain structure and cognitive impairment and is a risk factor for Alzheimer's disease and vascular dementia.
- Trial name
- NCT03215888
- Testing
- bariatric surgery
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Minnesota
COPD - Chronic Obstructive Pulmonary Disease, Healty Controls
Hemodynamic Responses and Brain Activity During Dual Tasks in COPD Patients Versus Healthy Individuals
Abstract Cognitive dysfunction is joint in patients with chronic obstructive pulmonary disease (COPD). In particular, there are effects in tasks that require attention, executive functions, and working memory related to the…
- Trial name
- NCT06974448
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Stroke
Quantifying Digital Behavior on Smart Phones - Data From Stroke Survivors
In this study, we want to continuously record the interaction of 50 stroke survivors with their smartphones during the first 3 months after discharge.
- Trial name
- QuantStroke (NCT04405635)
- Testing
- No intervention or exposure
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Chronic Kidney Disease (Stage 3-4), Vascular Function
Equol and Vascular Function in Women With Chronic Kidney Disease
The risk of cardiovascular disease (CVD) is significantly elevated in patients with chronic kidney disease (CKD). Notably, women with CKD commonly experience menstrual disturbances induced by CKD, which may contribute to impaired…
- Conditions
- Chronic Kidney Disease (Stage 3-4), Vascular Function, Cognitive Functions, Cerebrovascular Function
- Trial name
- NCT07194590
- Testing
- Equol
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Colorado, Denver
MCI, MCI-AD, Early Stage Alzheimer's Disease
Efficacy and Safety of Dimethyl Fumarate Among Patients with Mild Cognitive Impairment and Dementia Due to Alzheimer's Disease
The goal of this clinical trial is to assess the degree of improvement in cognitive functions, including memory, attention, thinking, executive and language functions in diagnosed patients MCI and AD taking dimethyl fumarate 480…
- Conditions
- MCI, MCI-AD, Early Stage Alzheimer's Disease, Alzheimer's Disease
- Trial name
- NCT06850597
- Testing
- dimethyl fumarate
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Insomnia, Cognitive Impairment
RESET-BRAIN: REhabilitation of SleEp and CogniTive Impairment in BReast Cancer Survivors Using an App-based Intervention
The goal of the study is to investigate whether treating insomnia using app-based cognitive behavioral therapy for insomnia (CBT-I) can improve cognitive impairment in breast cancer survivors compared to an active control group…
- Conditions
- Insomnia, Cognitive Impairment, Breast Cancer
- Trial name
- RESET-BRAIN (NCT06553235)
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep hygiene education
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- Aarhus University Hospital
Major Depressive Disorder (MDD), Cognitive Dysfunction
Cognitive Rehabilitation for Veterans With MDD-related Cognitive Functioning Deficits
Individuals with depression often describe difficulties with memory, attention, concentration, and overall cognitive functioning, which can persist even after mood episodes get better, and can affect treatment and health…
- Trial name
- NCT06728774
- Testing
- Motivationally Enhanced Compensatory Cognitive Training for Major Depressive Disorder (ME-CCT-MDD), Goal-focused Supportive Contact
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Portland VA Medical Center
Mild Traumatic Brain Injury, Functional Neurological Disorder
Rehabilitation for Functional Memory Symptoms After Concussion
This study aims to evaluate the feasibility of novel cognitive behavioural therapy (CBT)-based intervention designed to improve functional memory symptoms after concussion.
- Trial name
- NCT05581810
- Testing
- Cognitive Behavioural Therapy (CBT), Cognitive Rehabilitation
- Where
- 10 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Primary Brain Tumor, Radiation Toxicity
Cognitive Function After Radiation Therapy for Brain Tumours
This study will assess cognitive function in adult patients with a primary brain tumour treated with surgical resection with or without radiation therapy (RT). All types of brain tumours apart from glioblastoma will be included
- Trial name
- WP-12-pre (NCT04118426)
- Testing
- Cognitive testing
- Where
- Denmark
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Healthy Subjects
On the Impact of Common Sweetening Agents on Glucose Regulation, Cognitive Functioning and Gut Microbiota
The study intention is to investigate, in healthy humans, effects of 3 commonly used sweeteners on cardiometabolic risk markers, cognitive functions, and influences on gut microbiota composition.
- Trial name
- NCT02580110
- Testing
- Sucrose, Stevia glycosides, saccharin
- Where
- Sweden
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Lund University
Dementia, Dementia, Vascular
Feasibility of the SmartPrompt for Improving Everyday Function in Dementia
Difficulty completing everyday tasks is a primary reason for the high cost of care, loss of caregiver paid hours, and general caregiver burden associated with dementia.
- Conditions
- Dementia, Dementia, Vascular, Dementia Alzheimers, Dementia, Mixed
- Trial name
- SmartPrompt (NCT04313582)
- Testing
- SmartPrompt smartphone application
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Temple University
Cognitive/Functional Effects, Metastatic Cancer
Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery
RATIONALE: Stereotactic radiosurgery may be able to send x-rays directly to the tumor and cause less damage to normal tissue. Radiation therapy uses high-energy x rays to kill tumor cells.
- Conditions
- Cognitive/Functional Effects, Metastatic Cancer, Neurotoxicity, Radiation Toxicity
- Trial name
- NCT01372774
- Testing
- stereotactic radiosurgery, whole-brain radiation therapy
- Where
- 37 sites in United States
- Volunteers
- 194 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Partial Epilepsy
Effects of Eslicarbazepine Acetate (Esl, Bia 2-093) on Cognitive Function in Children With Partial Onset Seizures
To evaluate the effects of eslicarbazepine acetate on cognition in comparison with placebo as adjunctive therapy in children aged 6 to 16 years old with refractory partial-onset seizures.
- Trial name
- NCT01527513
- Testing
- Eslicarbazepine acetate (BIA 2-093)
- Where
- 36 sites in Italy, Netherlands and 3 more
- Volunteers
- 123 people
- Sponsor
- Bial - Portela C S.A.
Vitamin D Deficiency, Musculoskeletal Diseases
Vitamin D in School Children
The primary purpose of this study it to investigate total circulating 25-hydroxyvitamin D (25(OH)D) in school children (aged 4-11years) in Northern Ireland; thereby establishing the prevalence of vitamin D status (deficiency…
- Conditions
- Vitamin D Deficiency, Musculoskeletal Diseases, Cognitive Delay, Mild
- Trial name
- DVinCHI (NCT05018988)
- Testing
- Oral vitamin D spray
- Where
- United Kingdom
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Neurological Disorders, Cognitive Impairment
Validation of the VIRADIA App for Neurological and Cognitive Diagnostics in Virtual Reality
The VIRADIA study aims to validate and assess the reliability of a newly developed Virtual Reality (VR) diagnostic platform designed for neurological and cognitive testing.
- Conditions
- Neurological Disorders, Cognitive Impairment, Motor Impairment, Neurodegenerative Diseases
- Trial name
- VIRADIA (NCT07268079)
- Testing
- VIRADIA - Virtual Reality Diagnostic Platform
- Where
- Slovakia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Gametherapy
Frailty, Sarcopenia
Comprehensive Geriatric Assessment in Adults Aged 40 Years and Older Living With HIV
People living with HIV are experiencing longer life expectancy due to effective antiretroviral therapy; however, they may develop age-related conditions earlier than the general population.
- Trial name
- HIV-AGE40 (NCT07453303)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Chronic and Episodic Headache, Headache Disorders
PERSONOLOGICAL STRUCTURE, COGNITIVE FUNCTIONS AND CENTRAL SENSITIZATION IN HEADACHE
Headache, in its episodic and chronic forms, cannot be considered solely as an isolated neurological symptom, but as a complex condition of a bio-psycho-social nature.
- Trial name
- AURA (NCT07268768)
- Testing
- Neuropsychological assessment
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Cystic Fibrosis
Cystic Fibrosis and Cognitive Function
The long-term goal of this project is to examine the effects of cystic fibrosis (CF) and cystic fibrosis related diabetes (CFRD) on brain structure and function
- Trial name
- NCT03820349
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Minnesota
Functional Movement Disorder, Fragility
Effect of a Dual-task Intervention Program on Physical and Cognitive Function
Aim: to compare the effects of single-task (ST) and dual-task (DT) training on physical and cognitive function in institutionalized older adults in 1 month.
- Trial name
- NCT06361615
- Testing
- Single-Task, Dual-Task
- Where
- Chile
- Volunteers
- 24 people
- Sponsor
- University of Americas - Chili
Transcranial Direct Current Stimulation, Schizophrenia
Maximizing the Impact of Neuroplasticity Using Transcranial Electrical Stimulation Study 2
Non-invasive neuromodulation, such as transcranial direct current stimulation ( tDCS) , is emerging as an important therapeutic tool with documented effects on brain circuitry, yet little is understood about h ow it changes…
- Conditions
- Transcranial Direct Current Stimulation, Schizophrenia, Schizoaffective Disorder
- Trial name
- MINUTES (NCT03896438)
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Minnesota
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