Clinical trials: Functional Cognitive Disorder
Pregnancy, Postpartum
HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children
Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior.
- Conditions
- Pregnancy, Postpartum, Childbirth, Health Status
- Trial name
- HIIT MAMA (NCT05009433)
- Testing
- High intensity interval training program for pregnant women, Moderate intensity continuous training program for pregnant women, Standard obstetric care with extended education on healthy lifestyle
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Huntington's Disease (HD), Exergame
Comparison of Two Cognitive-Motor Rehabilitation Approaches Via Exergames: a Study of Cognitive, Motor and Behavioral Functions in Huntington's Disease Patients
Huntington's disease (HD) is a rare, hereditary neurodegenerative disorder. It generally manifests itself between the ages of 40 and 50, and results in motor impairment (choreic movements, balance disorders, gait disorders…
- Trial name
- CARE-MH (NCT06807892)
- Testing
- Synergistic management, Sequential management
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Angers
Postoperative Cognitive Dysfunction
LINC01844 as a Diagnostic Biomarker for POCD in Elderly Patients
Postoperative cognitive dysfunction (POCD) is a common complication after surgery that is associated with more adverse events and death.
- Trial name
- NCT06387836
- Testing
- Isoflurane 0.8 MAC, Desflurane 0.8MAC
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Shanghai Zhongshan Hospital
Attention Deficit Hyperactivity Disorder
Training Executive, Attention and Motor Skills (TEAMS): Preliminary Studies
Training Executive, Attention and Motor Skills (TEAMS) is a new research program for preschool children with Attention-Deficit/Hyperactivity Disorder (ADHD) that attempts to use game-like activities and physical exercise to…
- Trial name
- TEAMS (NCT01073176)
- Testing
- TEAMS (Training Attention Executive and Motor Skills)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Queens College, The City University of New York
Anxiety Disorder, Breast Cancer
Mindful Movement Program in Improving Quality of Life in Older Female Breast Cancer Survivors
RATIONALE: Mindful movement is a self-directed activity of mindfulness (intention, attention, and attitude) and physical movement.
- Conditions
- Anxiety Disorder, Breast Cancer, Cancer Survivor, Cognitive/Functional Effects
- Trial name
- NCT00903474
- Testing
- questionnaire administration, study of socioeconomic and demographic variables, CAM exercise therapy
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- City of Hope Medical Center
Influenza
Effect of Oseltamivir on Cognitive Function in Subjects With Influenza
This study has been designed to determine if subjects treated with oseltamivir in addition to standard of care treatment for influenza demonstrate a greater improvement in attention / working memory / processing speed / mood as…
- Trial name
- FOCUS (NCT01249833)
- Testing
- Oseltamivir
- Where
- 16 sites in Canada
- Volunteers
- 122 people
- Sponsor
- Trial Management Group Inc.
The Association of Postoperative Cognitive Dysfunction With Glymphatic Function and Neuroinflammation, The Association of Postoperative Cognitive Dysfunction With CSF Metabolomic Change
CSF Metabolomics and Glymphatic Function in Patients Receiving VP- Shunt Surgery.
In this randomized control study, the investigators intended to evaluate the influence of different anesthetics on postoperative cognitive dysfunction, neuroinflammation, CSF metabolomics, and glymphatic function in patients with…
- Trial name
- NCT06005363
- Testing
- Dexmedetomidine, anesthesia depth monitoring
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Chang Gung Memorial Hospital
Attention Deficit Hyperactivity Disorder (ADHD), ADHD
Effects of Phosphatidylserine and DHA on Cognitive Performance in Children With ADHD
This study aimed to evaluate the effects of different phosphatidylserine (PS) formulations, with or without docosahexaenoic acid (DHA), on cognitive performance in children diagnosed with attention-deficit/hyperactivity disorder…
- Trial name
- PS-DHA-ADHD (NCT07521449)
- Testing
- Phosphatidylserine-Omega3, DHA Omega-3
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Çağlar Charles Daniel Jaicks
Obesity, Neurofeedback
Real-time NIRS Neurofeedback Regulating Brain Cognitive Function in Obese Individuals
To determine the efficacy of real-time fNIRS neurofeedback for regulating the brain cognitive function in obese individuals.
- Trial name
- NCT04071717
- Testing
- NIRS neurofeedback
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Wu Wenjun-1
Aging, Arterial Stiffness
Inorganic Nitrate Supplementation on Cerebrovascular Aging and Arterial Stiffness Study
This study investigates the effect of dietary inorganic nitrate supplementation on 1) large elastic artery stiffness and hemodynamics and 2) cerebrovascular function in middle-aged and older adults.
- Conditions
- Aging, Arterial Stiffness, Endothelial Dysfunction, Hypertension
- Trial name
- INCA (NCT03617302)
- Testing
- Experimental: Nitrate-containing
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gary L. Pierce, PhD
Cardiometabolic Health, Gastro-intestinal Wellbeing
Effects of Wholegrains on Children's Health (KORN)
KORN investigates the effects of wholegrain oat and rye intake on health and cognitive wellbeing in children with overweight.
- Conditions
- Cardiometabolic Health, Gastro-intestinal Wellbeing, Cognitive Function, Overweight
- Trial name
- NCT04430465
- Testing
- Grain products high in wholegrains from oat and rye, Grain products low in wholegrains
- Where
- Denmark
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Focal Epilepsy
The Effects on Cognitive Function of Levetiracetam (Keppra®) Compared to Carbamazepine (Tegretol®, Carmazepine®) as Monotherapy for Children With Partial Seizure; A Multicentric Randomized Controlled Study
Unlike the first generation antiepileptic medications, newer drugs for epilepsy such as levetiracetam are reported to have less adverse effect in children but not many studies have systematically reviewed the subject.
- Trial name
- NCT02208492
- Testing
- Levetiracetam, Carabamazepine
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Yonsei University
Brain and Central Nervous System Tumors, Cognitive/Functional Effects
Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors
RATIONALE: Methylphenidate may decrease side effects of radiation therapy. It is not yet known if methylphenidate is effective in improving quality of life in patients with primary or metastatic brain tumors.
- Conditions
- Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Depression, Fatigue
- Trial name
- NCT00031798
- Testing
- methylphenidate hydrochloride, quality-of-life assessment, radiation therapy
- Where
- 7 sites in United States
- Sponsor
- Wake Forest University Health Sciences
Mild Cognitive Impairment, Alzheimer Dementia
Effects of Muscle Relaxation on Cognitive Function in Patients With Mild Cognitive Impairment and Early Stage Dementia.
Muscle relaxation has been reported to be effective in alleviating anxiety and agitation symptoms in patients with dementia, but no studies have examined the effects of muscle relaxation therapy on cognitive function changes.
- Trial name
- NCT03507192
- Testing
- Muscle relaxation using full body massage machine
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Parkinson Disease
Acute Effects of Cycling Dual-task in Parkinson´s Disease.
Taking into account the process of functional and cognitive evolution that patients with Parkinson's disease experience throughout the pathology, the objective of this study is to evaluate the acute effects of aerobic exercise in…
- Trial name
- NCT05375032
- Testing
- Cycling combined with cognitive tasks, Cycling
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- University of Vigo
Subjects With Mild Cognitive Impairment (MCI) of AD, Alzheimer's Disease (AD) Dementia
Evaluate the Use of [18F]-APN-1607 PET in Subjects With AD-related Cognitive Impairment and Subjects With Normal Cognitive Function
This study is to evaluate the efficacy and safety of [18F]-APN-1607 Injection in PET imaging for detecting AD-related cognitive impairment.
- Trial name
- NCT07422857
- Testing
- [18F]-APN-1607
- Where
- 2 sites in China
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- JYAMS PET Research & Development Limited
Mild Cognitive Impairment, Memory Disorders
A Study of HD-tDCS and Cognitive Training to Improve Cognitive Function in MCI
The primary objective of this project is to assess the feasibility of multi-field, extended HD-tDCS (MFE-HD-tDCS) with simultaneous computerized CT as a viable intervention to improve cognitive function in patients with MCI.
- Conditions
- Mild Cognitive Impairment, Memory Disorders, Memory Loss
- Trial name
- NCT04246164
- Testing
- HD-tDCS combined with CT
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Medical College of Wisconsin
Multiple Sclerosis
Electrical Brain Stimulation for Treatment of Secondary Symptoms in Multiple Sclerosis
Multiple Sclerosis (MS) is an autoimmune disease associated with physical disability, psychological impairment, and cognitive dysfunction. As a result, the disease burden is high, and treatment options are limited.
- Trial name
- NCT06401928
- Testing
- transcranial direct current stimulation, transcranial direct current stimulation combined with cognitive training
- Where
- Iran
- Volunteers
- 53 people
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Social Phobia
Treatment of Social Phobia Over the Internet
Forty-eight people diagnosed with social phobia in an experimental study that randomized into two treatment groups: 1) Internet-based Cognitive Behavioural Therapy (iCBT) (n = 24) or 2) computerized attention training (n = 24).
- Trial name
- SOFIE-8 (NCT01312571)
- Testing
- Internet-based cognitive behavioural therapy (iCBT), Internet-based computerized attention training
- Where
- Sweden
- Volunteers
- 26 people
- Sponsor
- Umeå University
Mild Cognitive Impairment (MCI)
A Comparison of the Efficacy of Different Rehabilitation Strategies in Mild Cognitive Impairment
The aim of this study is to conduct a comparative analysis of the effects of two different rehabilitation approaches on cognitive and functional outcomes in older adults diagnosed with mild cognitive impairment (MCI).
- Trial name
- NCT07547111
- Testing
- Dual Task Training, The computer-assisted cognitive rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul University - Cerrahpasa
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