Clinical trials: Functional Cognitive Disorder
Stress
CALM Study: Can A Prebiotic Fibre bLend Improve Stress, Mood, and Anxiety?
This clinical trial will investigate whether a powdered prebiotic fibre blend can improve perceived stress levels in healthy adults with mild-severe stress levels.
- Trial name
- CALM (NCT07201909)
- Testing
- Prebiotic fibre blend, Maltodextrin powder
- Where
- United Kingdom
- Volunteers
- 156 people
- Sponsor
- Myota GmbH
Parkinson's Disease
Effect of Stimulus Rate on Cognitive and Motor Activity in Young Subjects, Elderly Subjects, and Patients With Parkinson's Disease
The purpose of this study is to investigate how changes in the brain associated with Parkinson's disease influence the control of motor and thinking speed.
- Trial name
- NCT00026598
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebral Small Vessel Diseases
CerebrAlcare Pills on CereBral Small VesseL DiseasE（CABLE）
This is a randomized, double-blinded, placebo-controlled, multicenter trial. Cerebral small vessel disease (CSVD) patients will be diagnosed by Magnetic Resonance Imaging (MRI) and randomized into treatment or control groups.
- Trial name
- NCT05578521
- Testing
- Cerebralcare pills
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Beijing Tiantan Hospital
Aphasia, Acquired
Effect of Participation in Virtual Exercise Sessions in Persons With Aphasia
The purpose of this study is to test the feasibility and acceptability of an online exercise program for community-dwelling individuals with aphasia, a language disorder resulting from brain damage.
- Trial name
- NCT05455463
- Testing
- Online aphasia-adapted physical activity class
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- California State University, East Bay
Spinal Cord Injury
Spinal Cord Injury: Impact on Sensory, Motor, Behavioral and Cognitive Functions
Spinal cord injury (SCI) causes a variety of sensory-motor deficits and neuropsychological consequences. Magnetic resonance imaging (MRI) reveals a reduction in the volume of the somato-sensory and motor cortices, as well as…
- Trial name
- SUPRASPINAL (NCT06887309)
- Testing
- MRI, Neuropsychological tests
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Delirium, Critical Illness
Driving Rehabilitation and Innovation for Evaluating Risk in Post-Intensive Care Unit Survivors
Older adults are at risk for ICU-acquired cognitive decline discernible from clinical, biological, and imaging- related changes in the brain following delirium and critical illness.
- Conditions
- Delirium, Critical Illness, Drive
- Trial name
- DRIVE-PICS (NCT05999903)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Baylor Research Institute
Long Covid
The Effect of Acupuncture Treatment on Cognitive Functions and Brain Networks for Long COVID
Background of study: Long COVID(LC) is a prevalent sequalae of SARS-CoV-2 infection and can affect multiple organ systems. Cognitive dysfunction is one of the most common symptoms in LC with 22% prevalence.
- Trial name
- NCT07355751
- Testing
- Acupuncture
- Where
- 2 sites in China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Tingting Luo
Cognitive Change
Executive Function Training for Children and Adolescents
The goal of this clinical trial is to evaluate how different approaches to executive function (like adding game-like features, varying the number of tasks, and providing coaching) can enhance executive function outcomes in…
- Trial name
- NCT07147894
- Testing
- Nongamified N-back training, Gamified N-back training, Multiple Domain Training
- Where
- United States
- Volunteers
- 780 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Parkinson Disease, Stroke
COMPuter-assisted Self-training to Improve EXecutive Function
This project explores the effects of specialized computer-based cognitive rehabilitation (CBCR) targeting executive functions in three groups of patients: Stroke, Cardiac Arrest and Parkinson's Disease.
- Conditions
- Parkinson Disease, Stroke, Cardiac Arrest, Cognitive Dysfunction
- Trial name
- COMPEX (NCT04229056)
- Testing
- Computer-based cognitive rehabilitation (CBCR), General computer-based cognitive stimulation
- Where
- 2 sites in Denmark
- Volunteers
- 307 people
- Sponsor
- Bispebjerg Hospital
Brain Neoplasms, Delirium - Postoperative
Ciprofol, Propofol and Sevoflurane for Postoperative Delirium in Elderly Brain Tumor Patients
This study will compare three anesthesia medicines used to put people into a deep sleep during surgery: ciprofol, propofol, and sevoflurane. All three are commonly used for general anesthesia, but they work in different ways.
- Trial name
- NCT07799623
- Testing
- Ciprofol, Propofol, Sevoflurane
- Where
- China
- Volunteers
- 381 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Melanoma, Cognitive Impairment
Cognitive Function in Melanoma Patients Treated With Adjuvant Immune Checkpoint Inhibitors
Immune checkpoint inhibitors (ICIs) are a group of novel immunotherapies that boost the body's own defense against the cancer by improving the immune system's ability to recognize and destroy cancer cells.
- Conditions
- Melanoma, Cognitive Impairment, Fatigue, Sleep
- Trial name
- NCT04565769
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
TBI (Traumatic Brain Injury), Brain Concussion
Dual-Task Exercise for Mild Traumatic Brain Injury (mTBI)
The investigators previously developed a virtual 14-day dual-task walking exercise program and tested its feasibility with individuals with mild traumatic brain injury (mTBI) history.
- Conditions
- TBI (Traumatic Brain Injury), Brain Concussion, Clinical Trial, Rehabilitation
- Trial name
- NCT06037603
- Testing
- Brain & Walk Exercise Every Day (BraW-Day)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Huntington Disease
Development of Assessments for Later Stage HD
Later Stage HD Assessments (LSA) is an observational, multinational study aiming at developing two assessments that can be used to measure critical milestones and events during the later stages of Huntington's disease (HD).
- Trial name
- LSA (NCT04370470)
- Where
- 20 sites in United States, United Kingdom
- Volunteers
- 340 people
- Sponsor
- CHDI Foundation, Inc.
Mild Cognitive Impairment
A Pilot Study of tDCS for Mild Cognitive Impairment
The primary objective of this preliminary study is to investigate whether the transcranial direct current stimulation (tDCS) improves the cognitive function in patients with Mild Cognitive Impairment (MCI)
- Trial name
- NCT02227966
- Testing
- Yband (YDT-201N)
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Schizophrenia
Effectiveness of a Board Game Intervention on Cognitive and Functional Outcomes in Older Adults With Schizophrenia
This study aims to evaluate the effects of a scaffolding-based board game intervention on cognitive and functional outcomes in older adults with schizophrenia living in psychiatric nursing homes.
- Trial name
- NCT07781007
- Testing
- Scaffolding-Based Board Game Intervention
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Kaohsiung Kai-Suan Psychiatric Hospital
Type 2 Diabetes
Marathon Runners Compared to Sedentary Matched Control Subjects
The investigators wish to compare very active runners in healthy untrained control subjects on a number of parameters. The project aims to understand the underlying mechanisms by which physical inactivity causes diseases.
- Trial name
- NCT02001805
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Inge Holm
Metabolism - Cerebral Energy
The Efficient Brain Study
Cerebral energy metabolism declines with advanced aging, and is implicated in age-related cognitive decline, Alzheimer's disease (AD), and other forms of neurodegenerative disease (Parkinson's disease).
- Trial name
- NCT02771366
- Testing
- Fermented Papaya Preparation, Granulated Sugar
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida
Multiple Sclerosis, Cognition Disorders
Linking Cognitive Functioning to Multimodal Imaging in Multiple Sclerosis (MS)
Multiple sclerosis (MS) is the most common progressive neurologic disorder to occur in adults of working-age. Despite longstanding recognition of cognitive impairment as a symptom of MS, two obstacles in measurement have limited…
- Trial name
- NCT03723356
- Testing
- Siemens Biograph mMR (molecular MR), fMRI, Diffusion Spectrum Imaging (DSI)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Traumatic Brain Injury, Cognitive Decline
Cognitive and Vascular Functioning Following TBI
This observational study will examine the association of chronic traumatic cerebrovascular injury and cardiovascular risk factors with TBI-related cognitive impairment and vascular dementia.
- Conditions
- Traumatic Brain Injury, Cognitive Decline, Vascular Dementia
- Trial name
- NCT06034509
- Testing
- No intervention. This is an observational study.
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Walter Reed National Military Medical Center
Schizophrenia, Major Depressive Disorder
Influence of rTMS on Symptoms and Cognitive Function in Patients With Psychiatric Disorders
The investigators investigated the effects of high frequency (10Hz) repetitive transcranial magnetic stimulation (rTMS) on the symptoms and cognitive functioning in patients with psychiatric disorders
- Trial name
- NCT04055181
- Testing
- rTMS in schizophrenia Controls, rTMS in schizophrenia patients, rTMS in major depressive disorders controls
- Where
- 6 sites in China
- Volunteers
- 800 people
- Sponsor
- Beijing HuiLongGuan Hospital
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