Clinical trials: Functional Cognitive Disorder
Posttraumatic Stress Disorder
A Case Formulation Approach to Cognitive Processing Therapy
Recent estimates suggest that over 610,000 US Veterans treated by the Veterans Health Administration (VHA) suffer from PTSD, a disorder that can be chronic and debilitating.
- Trial name
- CF-CPT (NCT04407767)
- Testing
- Case Formulation plus Cognitive Processing Therapy, Cognitive Processing Therapy
- Where
- 8 sites in United States
- Volunteers
- 194 people
- Sponsor
- VA Office of Research and Development
Aphasia, Stroke
Brain-based Understanding of Individual Language Differences After Stroke
Strokes often cause a loss of communication ability, referred to as aphasia, as well as cognitive difficulties. Each stroke survivor has a unique pattern of strengths and weaknesses in communication and cognition, and a unique…
- Conditions
- Aphasia, Stroke, Alexia
- Trial name
- BUILD (NCT04991519)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Mild Neurocognitive Disorder
Effectiveness of a Novel Exergame-Based Training Concept for Older Adults With Mild Neurocognitive Disorder
BACKGROUND: Simultaneous motor-cognitive training interventions are considered promising to prevent the decline in cognitive functioning in older adults with mild neurocognitive disorder (mNCD) and can be highly motivating when…
- Trial name
- NCT05387057
- Testing
- Exergame training according to the 'Brain-IT' exergame-based training concept, Usual Care
- Where
- Switzerland
- Volunteers
- 41 people
- Sponsor
- Eling DeBruin
Attention Deficit Hyperactivity Disorder
The Efficacy of Computerized Cognitive Training in Adults With ADHD: Change in ADHD Symptoms, Executive Functions and Quality of Life Following Three Months of Training.
The study group of Adults with ADHD who will receive cognitive (executive attention) computerized training will show significant improvement in ADHD symptomatology,neuropsychological measures,daily functioning and quality of…
- Trial name
- NCT00843141
- Testing
- cognitive computerized training, simple cognitive computerized training
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Hadassah Medical Organization
Malaria,Falciparum, Anemia in Children
Comparing Chemoprevention Approaches for School-based Malaria Control
This is an individually randomized, controlled, single blind three arm clinical trial of malaria chemoprevention strategies Arm 1: Intermittent screening and treatment (IST) - students will receive treatment if they have a…
- Trial name
- NCT05244954
- Testing
- Dihydroartemisinin-Piperaquine, Chloroquine
- Where
- Malawi
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Mild Cognitive Impairment
DIetary Supplements, Executive funcTions and Vitamin D (DIET-D)
The purpose of this study is to compare the effect after 12 weeks of the oral intake of Lecitone®Se + 200UI/day of D3 vitamin with the effect of a placebo on changes in cognitive performance in Trial Making Test score part B…
- Trial name
- DIET-D (NCT01708005)
- Testing
- Lecitone®Se-Vitamin D3
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Angers
Cognitive Impairment, Schizophrenia
Cognitive Rehabilitation in Schizophrenia
The study will investigate the viability of two cognitive rehabilitation strategies to improve functional outcomes for people with schizophrenia.
- Trial name
- NCT00248794
- Testing
- Cognitive Rehabilitation Therapy (CRT) + Skill Training (SDG), Individual Computer Based Cognitive Rehabilitation (ICBCR) and Skills Training (SDG), Skills Group (SDG)
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- VA Office of Research and Development
Schizophrenia
Efficacy Study on Cognitive Functions in Schizophrenic Patients
Primary objectives To compare neurocognitive effects of amisulpride with those of risperidone in patients with chronic schizophrenia, as assessed by the general cognitive index, a measure of overall cognitive functioning in…
- Trial name
- AMIMIND (NCT00761670)
- Testing
- amisulpride and risperidone
- Where
- Hungary
- Volunteers
- 37 people
- Sponsor
- Sanofi
Parkinson Disease
Cognitive-driven ADL Impairment as a Predictor for PDD
Mild cognitive impairment in Parkinson's disease (PD-MCI) is the highest risk factor for Parkinson's disease dementia (PDD). The core feature for differentiating PDD from PD-MCI is the loss of the ability to perform activities of…
- Trial name
- NCT03687203
- Testing
- Functional Activities Questionnaire
- Where
- Germany
- Volunteers
- 182 people
- Sponsor
- University Hospital Tuebingen
Schizophrenia, Memory Disorders
The Effects of Atomoxetine on Cognition and Brain Function Based on Catechol-O-methyltransferase(COMT) Genotype
This study will evaluate whether Atomoxetine improves cognition in healthy volunteers as well as patients with schizophrenia. Atomoxetine is a drug that has been Food and Drug Administration (FDA) approved for Attention Deficit…
- Conditions
- Schizophrenia, Memory Disorders, Cognition Disorders
- Trial name
- Atomoxetine (NCT00548327)
- Testing
- Atomoxetine, Functional magnetic resonance imaging, Neuropsychological Testing
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Hearing Loss, Cognitive Impairment, Mild
ENACT Program on Auditory Perception and Function, Cognitive Function and Health-related Quality of Life
Although previous studies indicated that tackling hearing loss may have a secondary benefit in improving cognitive function and delaying the onset of dementia, a more integrated care approach to optimize both hearing and…
- Trial name
- NCT06955494
- Testing
- Empowerment Network for Auditory-Cognitive Training (ENACT) Program, Usual Care
- Where
- Hong Kong
- Volunteers
- 62 people
- Sponsor
- The University of Hong Kong
Irritable Bowel Syndrome
Self Administered Cognitive Behavior Therapy for Irritable Bowel Syndrome
The primary goal of the proposed trial is to assess the short- and long-term efficacy of cognitive behavior therapy (CBT) for irritable bowel syndrome using two treatment delivery systems (self administered, therapist…
- Trial name
- NCT00738920
- Testing
- Self Administered Cognitive Behavior Therapy, Therapist Administered Cognitive Behavior Therapy, Behavioral Education and Supportive Therapy
- Where
- 2 sites in United States
- Volunteers
- 436 people
- Sponsor
- State University of New York at Buffalo
Alzheimer's Disease
Computerized Cognition Testing in Participants With Mild Alzheimer's Disease (AD) Treated With Donepezil (MK-0000-318)
This study aims to determine whether the Cogstate testing battery can detect improvements in cognitive function in participants with mild AD.
- Trial name
- NCT02064920
- Testing
- Donepezil
- Volunteers
- 36 people
- Sponsor
- Merck Sharp & Dohme LLC
Myotonic Dystrophy 1
Evaluation of Cognitive Functions in 20 Patients With Type 1 Myotonic Dystrophy With Virtual Reality Approach
Type 1 myotonic dystrophy (MD1) is a genetic and hereditary disease that primarily affects muscle tissue, resulting in myotonia (difficulty relaxing after contraction) and atrophy (progressive muscle weakening with decreased…
- Trial name
- GoodDiagNMD (NCT06270186)
- Testing
- Type 1 myotonic dystrophy
- Sponsor
- Centre Hospitalier Universitaire de Nice
Depressive Symptoms, Anxiety
Probiotics, Brain Structure and Psychological Variables
Theory and research on the gut-brain-axis emphasize complex interactions between the gut microbiota, immunological and hormonal responses, brain function, brain structure, as well as resulting behavioral manifestations, such as…
- Conditions
- Depressive Symptoms, Anxiety, Stress
- Trial name
- ProBrain01 (NCT03478527)
- Testing
- Vivomixx® powder
- Where
- Germany
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Cerebral Palsy
Serious Games for Serious Outcomes: Enhancing Cognition, Balance, and Quality of Life in Children With Cerebral Palsy
Children with cerebral palsy (CP) often face challenges with balance, movement, and skills such as memory, problem-solving, and attention. These difficulties can affect not only daily activities but also their quality of life.
- Trial name
- Games4CP (NCT07158424)
- Testing
- Serious games, Intensive rehabilitation, Physical therapy
- Where
- Ukraine
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nataliya Hrabarchuk
Sleep Duration, Child Obesity
Effect of Sleep Extension on Body Weight and Learning in Children (More2Sleep)
More2Sleep is a randomized, controlled, parallel trial with two groups (sleep extension vs control) including 142 school-aged children (6-12 years) who have a BMI above average, defined as age- and sex-specific BMI Z-score above…
- Conditions
- Sleep Duration, Child Obesity, Child Development, Child Behavior
- Trial name
- More2Sleep (NCT06341179)
- Testing
- Sleep extension
- Where
- 3 sites in Denmark
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Fibromyalgia Syndrome
Effects of Basic Body Awareness Therapy Added to Aerobic Exercise in Women With Fibromyalgia
This study aims to investigate the effects of Basic Body Awareness Therapy combined with aerobic exercise on inflammatory biomarkers (interleukin-6 and cortisol), cognitive functions, and depression levels in women diagnosed with…
- Trial name
- BBAT-FMS (NCT07851896)
- Testing
- Basic Body Awareness Therapy, Moderate-Intensity Aerobic Exercise
- Volunteers
- 40 people
- Sponsor
- Hacer Önen Tekin
Brain Abscess, Fatigue
Cognitive Function and Fatigue After Brain Abscess
Brain abscess is a focal bacterial or fungal infection of the brain. Treatment is neurosurgical drainage of pus followed by long-term antibiotic treatment.
- Conditions
- Brain Abscess, Fatigue, Cognitive Dysfunction
- Trial name
- NCT04938362
- Testing
- FDG-PET, EEG
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University of Oslo
Recurrent Depressive Disorder
Study to Evaluate Cognitive Functioning in Remitted Depression During Treatment With Fluvoxamine
Open label, non-comparative, prospective study to evaluate cognitive functioning in remitted depression outpatients during long-term preventive treatment with Fluvoxamine (Fevarin®)
- Trial name
- NCT02016261
- Testing
- Fluvoxamine
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Moscow Research Institute of Psychiatry
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