Clinical trials: Functional Cognitive Disorder
Thoracic Anesthesia, Geriatric Anesthesia
The Effect of Single Lung Ventilation Duration and Intraoperative Brain Oxygenation on Cognitive Function and Postoperative Pain in Geriatric Patients
One lung ventilation (OLV) is commonly used in thoracic surgery. Although the lack of ventilation of the lung in the surgical area (independent lung) during OLV redirects pulmonary blood flow to the dependent lung, shunt…
- Conditions
- Thoracic Anesthesia, Geriatric Anesthesia, One Lung Ventillation (OLV), POCD - Postoperative Cognitive Dysfunction
- Trial name
- NCT07339124
- Testing
- Cognitive Remediation, Pain Medicine
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Tinnitus, Epilepsy, Temporal Lobe
Pathophysiology, Psycho-emotional and Cognitive Functioning Associated With Tinnitus
the investigators have recently shown that patients with drug-resistant temporal lobe epilepsy who have undergone brain surgery targeting the medial temporal lobe structures were more likely to develop tinnitus postoperatively.
- Trial name
- AudiCog (NCT04717388)
- Testing
- acoustics tests, Questionaries,, MRI
- Where
- 2 sites in France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post-Concussion Syndrome, Concussion, Brain
Personalized Brain Stimulation to Treat Chronic Concussive Symptoms
The goal of this study is to investigate a new treatment for chronic symptoms after concussion or mild traumatic brain injury in people aged 18-65 years old.
- Conditions
- Post-Concussion Syndrome, Concussion, Brain, Mild Traumatic Brain Injury, Head Injury
- Trial name
- NCT06073886
- Testing
- Active cTBS, Imaginal exposure
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of California, Los Angeles
Vascular Diseases
Cognitive Training in Stroke Patients
The study aims to investigate the behavioral effects, neural correlates and functional connectivity of cognitive training in patients with stroke
- Trial name
- NCT03644290
- Testing
- Cognitive training, Control Condition
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Alzheimer's Disease (AD)
Exploration of the Efficacy and Mechanisms of Lymphaticovenous Anastomosis in the Treatment of Alzheimer's Disease
The aim of this clinical trial is to determine whether Lymphaticovenous Anastomosis can treat Alzheimer's disease，in AD patients aged 18-80.he main questions it aims to answer are: 1.
- Trial name
- NCT06706947
- Testing
- Lymphaticovenous Anastomosis
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Luo Xinxin
Heart Failure, Mild Cognitive Impairment
Impact of Yoga on Cognitive Function
Mild cognitive impairment is highly prevalent in patients with heart failure and results in poor well-being and quality of life.
- Trial name
- NCT06434168
- Testing
- Yoga intervention, Control condition
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Auburn University
Healthy, Brain Insulin Sensitivity
Long-Term Effects of Walnut Consumption on Brain Function
Rationale: Healthy foods, including mixed nuts, may improve brain function, which is essential for cognitive and metabolic health, and may contribute to improved food intake regulation.
- Conditions
- Healthy, Brain Insulin Sensitivity, Cerebral Blood Flow, Brain Vascular Function
- Trial name
- WalBrain (NCT07422220)
- Testing
- Walnuts
- Where
- Netherlands
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Alcohol Use Disorders
Effect of Cognitive Training on Alcohol Use Outcomes
To purpose of the present study is to investigate the feasibility and efficacy of a computerized working memory training in improving cognitive functioning and alcohol use outcomes, in individuals with alcohol use disorders.
- Trial name
- COGALC (NCT02113618)
- Testing
- Cogmed training, Standard Training
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska University Hospital
Psychotic Disorders, Schizophrenia
Examining the Efficacy of a Virtual Reality Cognitive Remediation Program for People Living With Psychosis
Individuals living with a psychotic disorder often experience changes to their thinking and social skills that can lead to challenges with work, school, relationships and living independently.
- Conditions
- Psychotic Disorders, Schizophrenia, Schizo Affective Disorder
- Trial name
- NCT05973110
- Testing
- Cognitive Remediation, Active Control
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Stroke, Cognitive and Attention Disorders and Disturbances
The RenAtt Method for Diagnosing and Treating Attention Problems After Stroke and Brain Injury, Further Validation of RehAtt® DiSTRO Assessment of Cognitive and Visual Function
Stroke is one of the most common long-term disabilities in the world. Despite better access to more effective acute treatment, WHO reports a prediction of almost a doubling of disability-adjusted life-years (DALYs) in 2050.
- Conditions
- Stroke, Cognitive and Attention Disorders and Disturbances, Digital Health, Screening Strategy
- Trial name
- NCT07762274
- Testing
- Oxford Cognitive Screen
- Where
- 3 sites in Italy, Sweden and 1 more
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Umeå University
Child Development, Cognitive Impairment
Estimating Premorbid Intellectual Functioning in Children and Measuring Change in Cognitive Functioning as Children Develop
Diagnosing and documenting the presence of abnormal change in cognitive functions (such as reasoning abilities) in children over time is of upmost importance when it comes to evaluating the impact of neurological injury, disease…
- Trial name
- NCT04153838
- Testing
- Cognitive test administration
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Alzheimer Disease, Mild Cognitive Impairment
TPSAlz - Transcranial Pulse Stimulation in Alzheimer's Disease
The goal of this study is to evaluate the effects of transcranial pulse stimulation (TPS) in modulating cognitive functions as well as structural and functional connectivity in individuals with mild cognitive impairment and early…
- Trial name
- TPSAlz (NCT07883148)
- Testing
- Transcranial pulse stimulation (TPS)
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- IRCCS San Raffaele Roma
Age-Related Cognitive Decline, Age-Related Memory Disorders
Memory Improvement With Docosahexaenoic Acid Study (MIDAS)
The purpose of this study is to investigate the effect of docosahexaenoic acid (DHA, 22:6n-3) in improving cognitive functions in subjects with age-related cognitive decline.
- Trial name
- MIDAS (NCT00278135)
- Where
- 14 sites in United States
- Volunteers
- 485 people
- Sponsor
- dsm-firmenich Switzerland AG
PTSD, Cognitive Function
Self-regulation of Prefrontal Cortex During Emotional Cognitive Control in PTSD
Deficits in emotional cognitive control are present in a number of clinical psychiatric populations including depression, anxiety, and PTSD.
- Trial name
- SPrC-PTSD (NCT04543513)
- Testing
- Real-time functional magnetic resonance neurofeedback (rtfMRI-nf)
- Where
- United States
- Sponsor
- Laureate Institute for Brain Research, Inc.
Fragile X Syndrome (FXS), Creatine Transporter Deficiency
Optical Imaging in X-linked Disorders.
Fragile X syndrome (FXS, OMIM #300624) and Creatine Transporter Deficiency (CTD, #300352) are the two most common causes of X-linked intellectual disability.
- Trial name
- IMAGINER (NCT06868979)
- Testing
- Clinical assessment, Parental questionnaires, Cognitive assessment
- Where
- France
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Depressive Symptoms, Parkinson's Disease
Rasagiline in Cognitive-impairment Related Depression: AzileCt in COgnitive-impairment Related DepressiOn
The primary endpoint for this study is the clinical response after 12 weeks of treatment, defined as a change in total score from baseline depressive symptoms as measured by the Beck Depression Inventory-Amended (BDI-IA) total…
- Trial name
- ACCORDO (NCT01055379)
- Testing
- Rasagiline
- Where
- 12 sites in Italy
- Volunteers
- 121 people
- Sponsor
- Lundbeck Italia S.p.A.
Alcohol Use Disorder Cognitive Decline
NEUROPSYCHOLOGICAL REHABILITATION FOR ALCOHOL USE DISORDERS
This investigation will take place between September 2024 and June 2025, with the objective of analyzing executive deficits and the impact of Neuropsychological Rehabilitation on Alcohol Use Disorder, comparing different…
- Trial name
- AUD (NCT06933186)
- Testing
- Neuropsychological rehabilitation, Weekly therapeutic groups
- Where
- Portugal
- Volunteers
- 48 people
- Sponsor
- University of Lisbon
Sleep Quality, Cognitive Functions
Sleep Quality and Cognitive Functions in Adults: A Cross-Sectional Study
This observational cross-sectional study aims to examine the association between sleep quality and cognitive functions in healthy young adults.
- Trial name
- NCT07387783
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Irritable Bowel Syndrome
Management of Irritable Bowel Syndrome in Primary Care (MIBS Trial)
Aims: 1. To pilot an randomized, controlled trial (RCT) to assess the effectiveness of the commonly prescribed medications in UK general practice for IBS: mebeverine (anti-spasmodic) and methylcellulose (bulking-agent) and of the…
- Trial name
- MIBS (NCT00934973)
- Testing
- mebeverine, methylcellulose, CBT website with support
- Where
- United Kingdom
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Hazel Everitt
Cognitive Function, Motor Activity
Effects of Exercise Training on Cognitive Function and Neurotrophic Factors in Overweight Adults
The BrainFit Study aims to examine acute effects of High Intensity Interval- vs Resistance or Combined program has benefits on Cognitive Function as well as on secretion and regulation of neurotrophic factors or neurotrophins in…
- Conditions
- Cognitive Function, Motor Activity, Obesity
- Trial name
- BrainFit (NCT02915913)
- Testing
- Experimental: High Intensity Interval, Resistance training, Plus: High Intensity Interval + Resistance Training
- Where
- Colombia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Santo Tomas
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