Clinical trials: Functional Cognitive Disorder
Depression
Effectiveness of Methylphenidate in Improving Cognition and Function in Older Adults With Depression
This study will evaluate the safety and effectiveness of methylphenidate in improving cognition and function in older adults with depression.
- Trial name
- NCT00602290
- Testing
- Citalopram, Methylphenidate (MPH)
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- University of California, Los Angeles
Dementia, Alzheimer Disease
Effects of Remote-based Resistance Training on Cardiometabolic Risk Factors, Cognitive Function, and Quality of Life in Adults Living With Alzheimer's Disease and/or Related Dementias
The investigators aim to study the effects of a 24-week remote-based resistance exercise training program on cardiovascular disease risk factors, cognitive function, and quality of life in older adults living with mild cognitive…
- Conditions
- Dementia, Alzheimer Disease, Dementia, Vascular, Lewy Body Disease
- Trial name
- NCT05004558
- Testing
- Remote-based Resistance Exercise Training
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Drexel University
Virtual Reality
Effect of Virtual Reality on Cognitive Skills
The aim of this study is to investigate the effects of virtual reality (VR) intervention on cognitive skills in children with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT06996678
- Testing
- virtual Reality, occupational therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Hacettepe University
Cognitive Assessment, Psychological Function
Snacks and Brain Health
This project will investigate whether daily snack consumption can improve memory, mood, and overall brain function in people with cognitive impairment.
- Conditions
- Cognitive Assessment, Psychological Function, GI Health
- Trial name
- NCT07348406
- Testing
- Pecan snack, Pretzel snack
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Texas Tech University Health Sciences Center
Traumatic Brain Injury
Transcranial Direct Current Stimulation and Computer-based Training for the Traumatic Brain Injury Rehabilitation
Traumatic Brain Injury (TBI) is a serious public health problem due to its high mortality and morbidity rates, mainly affecting young adult males.
- Trial name
- NCT03382626
- Testing
- anodal tDCS, Computer-assisted training
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
The Association of Postoperative Cognitive Dysfunction With Glymphatic Function and Neuroinflammation, The Association of Postoperative Cognitive Dysfunction With CSF Metabolomic Change
CSF Metabolomics and Glymphatic Function in Patients Receiving VP- Shunt Surgery.
In this randomized control study, the investigators intended to evaluate the influence of different anesthetics on postoperative cognitive dysfunction, neuroinflammation, CSF metabolomics, and glymphatic function in patients with…
- Trial name
- NCT06005363
- Testing
- Dexmedetomidine, anesthesia depth monitoring
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Chang Gung Memorial Hospital
Pregnancy, Postpartum
HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children
Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior.
- Conditions
- Pregnancy, Postpartum, Childbirth, Health Status
- Trial name
- HIIT MAMA (NCT05009433)
- Testing
- High intensity interval training program for pregnant women, Moderate intensity continuous training program for pregnant women, Standard obstetric care with extended education on healthy lifestyle
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Alzheimer Disease
Holistic Nursing Benefits Cognitive and Psychiatric Symptoms in Alzheimer's Patients
This clinical study aims to evaluate the effects of a holistic nursing (HN) intervention on cognitive function, psychological well-being, and overall health outcomes in patients with Alzheimer's disease (AD).
- Trial name
- NCT06868004
- Testing
- Holistic Nursing
- Where
- China
- Volunteers
- 105 people
- Sponsor
- The First People's Hospital of Jingzhou
Mild Cognitive Impairment (MCI), AMCI - Amnestic Mild Cognitive Impairment
Effects of Combined Aerobic and Cognitive Training in a Simultaneous or Sequential Paradigm on Cognition and Brain Functional Activity in Patients with AMCI
Mild Cognitive Impairment (MCI) is a condition in which patients show an objective evidence of impairment in one or more cognitive domains but a spared independence in daily functional abilities.
- Conditions
- Mild Cognitive Impairment (MCI), AMCI - Amnestic Mild Cognitive Impairment, Neurodegenerative Dementia, Neurodegenerative Disease
- Trial name
- NCT06755164
- Testing
- Simultaneous aerobic and cognitive training (SIM), Sequential aerobic and cognitive training (SEQ)
- Where
- Italy
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
IBS - Irritable Bowel Syndrome
RCT of VR Therapy for IBS
Through a pilot randomized controlled trial (RCT), the aim is to test the clinical impact and feasibility of a virtual reality (VR) cognitive behavioral therapy (CBT) program versus sham VR among patients with irritable bowel…
- Trial name
- NCT06687616
- Testing
- SynerGI
- Where
- 2 sites in United States
- Volunteers
- 73 people
- Sponsor
- Christopher Almario
Cerebral Lesion, Cognitive Deficit Following Brain Lesions
Brain Injury and Cognitive Function
The objective of this exploratory study is to elucidate the underlying cerebral mechanisms of cognitive deficits. To achieve this, the investigator will apply functional brain imaging techniques to patients suffering from…
- Trial name
- NCT05922748
- Testing
- imaging, Evoked Potentials, MEG
- Where
- France
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Prodromal Schizophrenia
Neurofeedback Training for High Risk Psychosis
Young people who are at great risk for developing psychosis have cognitive deficits which are strongly related to functioning in the community.
- Trial name
- NCT03447548
- Testing
- Neurofeedback processing speed training, Active control
- Where
- 2 sites in United States
- Volunteers
- 81 people
- Sponsor
- Hartford Hospital
COPD - Chronic Obstructive Pulmonary Disease, Healty Controls
Hemodynamic Responses and Brain Activity During Dual Tasks in COPD Patients Versus Healthy Individuals
Abstract Cognitive dysfunction is joint in patients with chronic obstructive pulmonary disease (COPD). In particular, there are effects in tasks that require attention, executive functions, and working memory related to the…
- Trial name
- NCT06974448
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Hepatitis C, Hepatitis B
Neurocognitive Functioning in Patients With Hepatitis C Pre- and Post-Treatment With Antiviral Medication
The estimated global prevalence of hepatitis C (HCV) infection is approximately 3% (170 million individuals). In Canada there are an estimated 240,000 people infected with HCV.
- Trial name
- NCT00188201
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Schizophrenia Disorders, Cognitive Dysfunction
Cognitive Remediation Therapy for Schizophrenia: Effects on EEG and Emotional Regulation
This study aims to determine whether Cognitive Remediation Therapy (CRT) can improve attention, memory, and emotional regulation in people with schizophrenia.
- Conditions
- Schizophrenia Disorders, Cognitive Dysfunction, Emotion Regulation Disorders
- Trial name
- CRT-SCHZ (NCT06936397)
- Testing
- Cognitive Remediation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beykoz University
Vitamin D Deficiency, Neurocognitive Dysfunction
Vitamin D Supplementation and Neurocognition
This study will evaluate the effect of vitamin D supplementation on the neurocognitive function of older people with lower than normal levels of vitamin D at baseline
- Trial name
- Dcog (NCT03019120)
- Testing
- Vitamin D
- Where
- Israel
- Sponsor
- Rambam Health Care Campus
Subjective Cognitive Decline
Polyamine-enriched Diet in Healthy Older Adults With Subjective Cognitive Decline
The overall objective of this study is to examine the effect of polyamine supplementation on cognitive performance of individuals with subjective cognitive decline.
- Trial name
- preSmartAge (NCT02755246)
- Testing
- Polyamine supplementation
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Pediatric Brain Tumor, Cognitive Impairment
Fitness to Aid the Brain and Cognitive Skills
The study will assess the feasibility of a pilot clinical trial of community-led aerobic exercise training for paediatric brain tumour survivors (PBTS) and the feasibility of a web-based platform to deliver this exercise…
- Trial name
- Fit ABCS (NCT05367076)
- Testing
- Web-based Aerobic Exercise Program
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- The Hospital for Sick Children
Elderly With Type 2 Diabetes
Effects of Nordic Walking in Water on Cerebrovascular Function and Cognitive Impairment in Elderly With Type 2 Diabetes
Nordic walking in water would more advantage than normal daily life in cerebrovascular function and cognitive function in elderly with type 2 diabetes.
- Trial name
- NCT05641090
- Testing
- Nordic walking in water, No exercise intervention
- Where
- Thailand
- Volunteers
- 36 people
- Sponsor
- Chulalongkorn University
Schizophrenia, Schizoaffective Disorder
Decision-Making in Schizophrenia: A Combined Neuroimaging and Experience Sampling Study
The goal of this clinical trial is to learn if attention and ways of thinking impact decision-making and brain processes related to decision-making in people with schizophrenia or schizoaffective disorder relative to people…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Control Subjects
- Trial name
- NCT06745479
- Testing
- Positive Emotion Upregulation
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
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