Clinical trials: Functional Cognitive Disorder
Alcohol Dependence
Individualized Treatment Program for Alcohol Problems
The purpose of this study is to determine if a treatment for alcohol dependence that is specifically tailored to patients' patterns of drinking and coping strategies can result in better outcomes than more standardized treatments.
- Trial name
- IATP (NCT00298792)
- Testing
- Cognitive Behavioral Treatment, Cognitive-behavioral treatment
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Remimazolam Besylate, Thoracoscopic Lobectomy
The Impact of Remimazolam Tosilate on Oxygenation and Postoperative Cognitive Function in Elderly Patients Undergoing Thoracoscopic Lobectomy
Background: During thoracoscopic lobectomy in elderly patients, one-lung ventilation (OLV) is a common procedure. However, this process is prone to cause hypoxemia and postoperative cognitive dysfunction (POCD), which seriously…
- Conditions
- Remimazolam Besylate, Thoracoscopic Lobectomy, Oxygenation, Postoperative Cognitive Dysfunction
- Trial name
- NCT07086911
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Jinqiao Qian
Exertional Heat Injury
Integrating Cognitive Assessments Into the Heat Tolerance Test After Exertional Heat Injury
This prospective observational study is to evaluate soldiers post-exertional heat injury (EHI) during a heat tolerant test (HTT) to investigate the impact on their cognitive performance.
- Trial name
- NCT06764264
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Medical Corps, Israel Defense Force
Mild Cognitive Impairment, MCI
Cognitive Therapy Software for Improving Cognitive Function for Patients With Mild Cognitive Impairment
Cognitive therapy software for improving cognitive function for patients with mild cognitive impairment
- Trial name
- SB-DEX (NCT06264557)
- Testing
- SB-100, Educational book
- Where
- 12 sites in South Korea
- Volunteers
- 140 people
- Sponsor
- Rowan
Mild Cognitive Impairment, Walking
Impact of a Multicomponent Exercise Program on Cognitive and Functional Outcomes in Patients With Mild Cognitive Impairment
The goal of this randomised clinical trial is to investigate the effectiveness of an innovative therapeutic exercise program emphasizing in dual-task exercises in people with amnestic Mild Cognitive Impairment.
- Conditions
- Mild Cognitive Impairment, Walking, Balance, Cognition
- Trial name
- MExeProMCI (NCT07334392)
- Testing
- Innovative therapeutic exercise program, Therapeutic exercise program, Flyer
- Where
- Greece
- Volunteers
- 45 people
- Sponsor
- University of Patras
Cavernous Sinus Meningioma, Proton-therapy
Long-term Cognitive and Functional Impact of Proton-therapy or Modern Fractionated Radiotherapy in Cavernous Sinus Meningioma: An Open-label Randomized 1:1 Phase III Study
Cavernous sinus meningiomas are close to optic nerve, pituitary gland, cranial nerve, and hippocampi. The doses delivered to these structures are crucial and radiotherapy of cavernous sinus meningiomas exposes patients to late…
- Conditions
- Cavernous Sinus Meningioma, Proton-therapy, Photon Radiotherapy, Cognitive Impairment
- Trial name
- COG-PROTON-01 (NCT05895344)
- Testing
- Proton-therapy, Photon radiotherapy
- Where
- 13 sites in France
- Volunteers
- 160 people
- Sponsor
- Centre Francois Baclesse
Breast Cancer, Breast Cancer Survivor
Effects of Supervised Aerobic Exercise on Biomarkers, Physical Function, and Quality of Life in Breast Cancer Survivors
This study evaluates the effects of a 12-week supervised aerobic exercise program in women who have completed primary treatment for early-stage breast cancer and are in remission.
- Conditions
- Breast Cancer, Breast Cancer Survivor, Aerobic Exercise
- Trial name
- NCT07798492
- Testing
- Supervised Aerobic Exercise Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Gazi University
Juvenile Huntington Disease, Juvenile-Onset Huntington Disease
Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease
The goal of this observational study is to learn about brain development in Juvenile-onset Huntington's Disease (JoHD). The main questions it aims to answer are: Is brain development different in JoHD than Adult-onset…
- Trial name
- NCT05707663
- Where
- 5 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of Iowa
COPD
Effects of Combined Cognitive Rehabilitation in COPD Patients
This study was to examine the effect of endurance training combined with cognitive training in patients with COPD. The intervention group underwent Cognitive Training added to Endurance Training and the control group underwent…
- Trial name
- NCT03907839
- Testing
- clinical trials
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculty of Medicine, Sousse
COPD
The Effects of Creative Dance Based Exercise Training on Respiratory, Balance and Cognitive Functions, Respiratory and Peripheral Muscle Strength and Functional Capacity in Patients With Chronic Obstructive Pulmonary Disease (COPD)
COPD is a common, preventable and treatable disease associated with an increased chronic inflammatory response of the airways and lungs to harmful gases and particles and characterized by progressive airflow restriction, which is…
- Trial name
- NCT04039334
- Testing
- Conventional Chest Physiotherapy, Creative Dance Based Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Bezmialem Vakif University
Breast Cancer, Cardiovascular Risk
Time Restricted Eating in Survivors Trial 2.0
After chemotherapy, older breast cancer survivors experience a faster decline in brain function. This can make it harder to enjoy life, stay social, and maintain independence.
- Conditions
- Breast Cancer, Cardiovascular Risk, Cognitive Function, Physical Function
- Trial name
- TEST2 (NCT07259434)
- Testing
- Time Restricted Eating, Healthy Eating Education
- Where
- Canada
- Volunteers
- 152 people
- Sponsor
- University of Toronto
Systemic Lupus Erythematosus
Memantine in Systemic Lupus Erythematosus
Neuropsychiatric manifestations of Systemic Lupus Erythematosus (NPSLE) are both common and an important source of morbidity. Of the case definitions for NPSLE syndromes that have recently been developed, cognitive dysfunction…
- Trial name
- NCT00181298
- Testing
- Memantine
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Johns Hopkins University
Frailty, Mild Cognitive Impairment
Influence of Square-stepping Exercise on Brain Activation, Cognitive Function and Physical Performance in Frail Elders With MCI
This study is to elucidate the possible mechanisms of SSE by examining brain activation differences between SSE patterns and usual walking, as well as the relationship between brain activity and SSE performance, between cognitive…
- Trial name
- NCT05173363
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- National Yang Ming Chiao Tung University
Multiple Sclerosis
Study of Social Cognition by Morphological and Functional Imaging in Multiple Sclerosis Patients
In recent years, studies have brought knowledge of the difficulties of social cognition in Multiple Sclerosis (MS). The brain tissue alteration at the origin of these difficulties in social cognition mechanisms remain poorly…
- Trial name
- SOCOG-MS (NCT02290587)
- Testing
- Brain MRI - Clinical and cognitive evaluation, MRI
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Healthy Volunteer
Effects of Interrupting Sedentary Behavior on Metabolic and Cognitive Outcomes in Children
Background: Some studies in adults have found that insulin and glucose blood levels are lower when a long period of sitting is broken up with walking, compared to sitting without breaks.
- Trial name
- NCT01888939
- Testing
- Walking on a Treadmill, Sedendary Activities Only
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Schizophrenia
A 20-Year Follow-up of First Episode Psychosis: Longitudinal Effects of Early Treatment Strategies and Relapse
The study aims to address the following questions: 1. Do subgroups defined by early medication choices, relapse, and medication taken over 20 years differ in clinical, cognitive, and functional outcomes? 2.
- Trial name
- NCT07616999
- Where
- China
- Volunteers
- 178 people
- Sponsor
- The University of Hong Kong
Thyroid Gland; Node, Pregnancy
Swedish Iodine in Pregnancy and Development in Children (SWIDDICH) Study
THE ULTIMATE GOAL of this project is to answer the question "In MILD IODINE DEFICIENCY (ID), should a tablet with vitamins and minerals, including 150 μg iodine/day be administered to pregnant women with a normal diet, to attain…
- Conditions
- Thyroid Gland; Node, Pregnancy, Cognitive Developmental Delay
- Trial name
- SWIDDICH (NCT02378246)
- Testing
- Iodine
- Where
- 4 sites in Sweden
- Volunteers
- 1,337 people
- Sponsor
- Göteborg University
Schizophrenia
Improving Real-world Function for Persons with Schizophrenia: a Single-case Experimental Design
Existing treatment for individuals with psychosis primarily targets positive symptoms but has only modest effects on cognition and negative symptoms.
- Trial name
- ImproFunc (NCT06790186)
- Testing
- Perceive, Recall, Plan and Perform intervention Interventions:
- Volunteers
- 27 people
- Sponsor
- Sykehuset Innlandet HF
Mild Cognitive Impairment
Memory Aid - Working Memory Training in Patients With Mild Cognitive Impairment.
Background: Mild Cognitive Impairment (MCI) is a condition characterized by memory problems more severe than normal cognitive changes due to old age, and less severe than dementia.
- Trial name
- MCI (NCT01991405)
- Testing
- Computerized Working Memory Training.
- Where
- Norway
- Volunteers
- 90 people
- Sponsor
- Sorlandet Hospital HF
Tramatic Brain Injury
The Effects of Chronic Exposure to Low-Level Blasts
Background: Repeated exposure to explosions may lead to changes in the way that people think or feel. Breachers (people trained to use explosives to get into buildings) are exposed to repeated blasts as part of their job.
- Trial name
- NCT01524822
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
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