Clinical trials: Functional Constipation
Irritable Bowel Syndrome With Constipation, Functional Constipation
IBS-C Questionnaire Study
The study is a multi-centre, observational study which enrolls 150 IBS-C patients and 150 non-IBS-C patients in China.
- Trial name
- NCT04968652
- Where
- 10 sites in China
- Volunteers
- 300 people
- Sponsor
- AstraZeneca
Rome IV Functional Constipation
Microbiome Analysis of Constipated Versus Non-constipation Patients
This study intends to evaluate the microbiome of chronically constipated patients as compared to those with a non-constipated gastrointestinal system.
- Trial name
- NCT04106232
- Testing
- No change in procedure except for specimen collection throughout procedure
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- HyGIeaCare, Inc.
Functional Constipation
Evaluation of the Efficacy of a New Specific Infant Formula in Case of Functional Constipation
This study aims to assess the clinical efficacy, safety and tolerance of a new formula containing a prebiotic and a mix of probiotics in the specific population of infants suffering from functional constipation through a…
- Trial name
- NCT05340712
- Testing
- new infant formula, Standard formula
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- United Pharmaceuticals
Constipation - Functional
Study on the Effect of Rhubarb Extract on Stool Frequency and Biological Markers of Intestinal Function in Seniors With Low Defecation
Randomized double-blind clinical study versus placebo evaluating the effect of supplementation with rhubarb extract on stool frequency and biological markers of intestinal function in seniors with a low number of defecations per…
- Trial name
- NCT05541991
- Testing
- single dose coated tablet Fruits & Fibres Rhubarbe with standardised rhubarb extract, double dose coated tablet Fruits & Fibres Rhubarbe with standardised rhubarb extract
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- ortis
Functional Constipation
A Proof of Concept Study of Pradigastat in Patients With Functional Constipation
The purpose of this study is to evaluate the efficacy, safety, and tolerability of pradigastat 20 and 40 mg as compared to placebo in patients with Functional Constipation.
- Trial name
- NCT04620161
- Testing
- Pradigastat Tablets 20mg, Pradigastat Tablets 40mg
- Where
- 25 sites in United States, China
- Volunteers
- 181 people
- Sponsor
- Anji Pharma
Constipation - Functional
Evaluation of the Effect of Chicory Inulin-type Fructans in Constipated Adults
Constipation is common in the general population, especially in women and in the elderly, which can significantly affect quality of life of the individual.
- Trial name
- NCT05447481
- Testing
- chicory inulin-type fructan
- Volunteers
- 40 people
- Sponsor
- Sensus
Functional Constipation
Linaclotide Safety and Efficacy in 2 to 5-Year-Old Participants With Functional Constipation
The purpose of this study is to evaluate the dose response, safety, and efficacy of linaclotide when compared with placebo in pediatric participants, 2 to 5 years of age, with Functional Constipation.
- Trial name
- NCT04110145
- Testing
- Linaclotide
- Where
- 18 sites in United States
- Volunteers
- 35 people
- Sponsor
- Allergan
Functional Constipation
Effect of an 8-week Bifidobacterium Lactis HN019 Supplementation on Functional Constipation
This prospective, two-arm (parallel groups), double-blind, randomized, placebo-controlled, multi-center clinical trial will investigate the effects of an 8-week Bifidobacterium lactis HN019 supplementation on stool frequency and…
- Trial name
- BifidoDigest (NCT04231162)
- Testing
- Active product, Control product
- Where
- 4 sites in France
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Danisco
Constipation - Functional
Assessing GS500 in Functional Constipation
This study is designed to evaluate the safety, tolerability and efficacy of GS500 as a superabsorbent hydrogel for relief of constipation in subjects with functional constipation.
- Trial name
- TRANSIT (NCT04887896)
- Testing
- GS500
- Volunteers
- 260 people
- Sponsor
- Gelesis, Inc.
Rome IV Functional Constipation
HygiRelief Procedure and HygiSample Evaluation for Functional Constipation
This study has a single center, prospective, open label design. The population will include patients diagnosed with Rome IV Functional Constipation who are at the time of study enrollment being managed with a stable dose of…
- Trial name
- NCT04532879
- Testing
- HygiPrep (HyGIeaCare System)
- Sponsor
- HyGIeaCare, Inc.
Functional Gastrointestinal Disorders, Infantile Colic
Observational Prospective Study With Probiotic Supplementation on Infants With FGDI
This observational prospective study evaluates the safety, tolerability and efficacy of a probiotic formula in infants with functional gastrointestinal disorders (FGDI)
- Conditions
- Functional Gastrointestinal Disorders, Infantile Colic, Functional Constipation
- Trial name
- NCT04944628
- Testing
- Probiotic
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- AB Biotics, SA
Functional Constipation
Prucalopride in Pediatric Subjects With Functional Constipation
To evaluate the efficacy of prucalopride compared to placebo for the treatment of functional constipation in a paediatric population, aged ≥ 6 months to < 18 years.
- Trial name
- FC (NCT01330381)
- Testing
- prucalopride, PEG 4000
- Where
- Netherlands
- Volunteers
- 215 people
- Sponsor
- Shire
Functional Constipation
Effect of Lactobacillus Gasseri DSM 27123 on Functional Constipation in Healthy Women
The primary objective is to determine the change in frequency of complete spontaneous bowel movements (CSBMs) after 4 weeks of oral supplementation with Lactobacillus gasseri DSM 27123 in healthy adult women with functional…
- Trial name
- NCT02592200
- Testing
- Lactobacillus gasseri DSM 27123
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- BioGaia AB
Constipation - Functional
Lubiprostone in Children With Functional Constipation
Study to determine if children (6-17 years old) with functional constipation will respond to being treated with lubiprostone for 12 weeks.
- Trial name
- NCT02042183
- Testing
- Lubiprostone
- Where
- 117 sites in United States, Belgium and 5 more
- Volunteers
- 606 people
- Sponsor
- Sucampo Pharma Americas, LLC
Functional Constipation, Healthy
Evaluating Efficacy of Investigational Products on Spontaneous Bowel Movements in Healthy People With ≤ 3 Complete Weekly Spontaneous Bowel Movements
Low and High doses of Actazin and Livaux will be compared against a control formula and placebo to evaluate how each investigational study product effects complete spontaneous bowel movements in healthy adults that currently…
- Trial name
- NCT03462199
- Testing
- Actazin (green kiwi powder) High Dose, Actazin (green kiwi powder) Low Dose, Control Formula (Actazin green kiwi powder + PreticX prebiotic)
- Where
- Canada
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- AIDP, Inc.
Chronic Functional Constipation
Effectiveness & Safety of Promelaxin® Microenemas Against Macrogol 4000 P.O. in Chronic Constipation in Children 6-48 Months
The study is aimed at the efficacy and safety evalutation of the study treatments through a 2-weeks study period and the subsequent follow-up-
- Trial name
- NCT02751411
- Testing
- micro-enema with Promelaxin, Macrogol 4000
- Where
- 4 sites in Italy
- Volunteers
- 158 people
- Sponsor
- Aboca Spa Societa' Agricola
Constipation - Functional
Evaluation of the Safety of Lubiprostone in Pediatric Participants Aged ≥ 6 Years to < 18 Years With Functional Constipation
A study of the safety of lubiprostone in pediatric participants aged ≥ 6 Years to < 18 years diagnosed with functional constipation.
- Trial name
- NCT02766777
- Testing
- Lubiprostone
- Where
- 13 sites in United States
- Volunteers
- 87 people
- Sponsor
- Sucampo Pharma Americas, LLC
Constipation - Functional
Effect of a Mixture of Fibers and Carbohydrates on Intestinal Transit in Children Diagnosed With Functional Constipation
Once the patients who are candidates to enter the study are identified, the patients will be randomly be assigned to two groups, according to the sequence: Group A: study product+wash out+control product Group B: control…
- Trial name
- VEGY-DOWN(A) (NCT04028258)
- Where
- 3 sites in Spain
- Volunteers
- 120 people
- Sponsor
- Laboratorios Ordesa
Constipation - Functional
Lubiprostone for Children With Constipation
This study is for children with constipation. Children who completed 3 months of treatment in the earlier study (NCT02042183): were invited to participate will receive lubiprostone for 9 more months will see if lubiprostone…
- Trial name
- NCT02138136
- Testing
- Lubiprostone
- Where
- 85 sites in United States, Belgium and 5 more
- Volunteers
- 419 people
- Sponsor
- Sucampo Pharma Americas, LLC
Constipation - Functional
HyGIeaCare Procedure for Chronic Constipation
To assess the safety and clinical effectiveness of using the FDA cleared HyGIeaCare System to relieve constipation in patients not responding to standard laxative treatment.
- Trial name
- NCT03335969
- Testing
- colon irrigation
- Where
- United States
- Sponsor
- HyGIeaCare, Inc.