Clinical trials: Functional Constipation (FC)
Functional Constipation
A Study to Assess Adverse Events and Change in Disease Activity in Pediatric Participants (Age 6 Months to <2 Years) With Functional Constipation Who Are Treated With Linaclotide
Functional constipation (FC) is a common healthcare problem in children of all ages, potentially due to genetic predisposition, inadequate fiber and fluid intake, and immobility.
- Trial name
- NCT05760313
- Testing
- Linaclotide
- Where
- 38 sites in United States, Bulgaria and 5 more
- Volunteers
- 19 people
- Sponsor
- AbbVie
Functional Constipation, Irritable Bowel Syndrome With Constipation
Linaclotide Safety and Efficacy in Pediatric Participants, 6 to 17 Years of Age, With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC)
The objective of LIN-MD-64 is to evaluate the safety and efficacy of 12 weeks of linaclotide therapy (72 μg daily) in comparison with placebo in pediatric participants, 6 to 17 years of age, who fulfill modified Rome III Criteria…
- Trial name
- NCT04026113
- Testing
- Linaclotide
- Where
- 115 sites in United States, Belgium and 12 more
- Volunteers
- 438 people
- Sponsor
- AbbVie
Functional Constipation (FC)
This is a Randomized, Double-blind, Placebo-controlled, Multicenter, Parallel-group Study of the Efficacy and Safety of 2 Weight-based Treatment Groups of Plecanatide Versus Placebo in Children and Adolescent Participants 6 to Less Than 18 Years of Age With FC
The goal of this clinical trial is to learn if plecanatide can treat functional constipation in children and adolescents aged 6 to less than 18 years.
- Trial name
- Trulance (NCT07723924)
- Testing
- plecanatide
- Where
- 29 sites in United States
- Volunteers
- 180 people
- Sponsor
- Bausch Health Americas, Inc.
Functional Constipation in Children Ages 6-17 Years
A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 6-17 Years Who Fulfill Modified Rome III Criteria for Child/Adolescent Functional Constipation (FC)
The purpose of this study was to evaluate dose response of the safety and efficacy of linaclotide for the treatment of functional constipation (FC), in children age 6-17 years.
- Trial name
- NCT02559570
- Testing
- LIN Dose A, LIN Dose B, LIN Dose C
- Where
- 62 sites in United States, Canada
- Volunteers
- 173 people
- Sponsor
- Forest Laboratories
Chronic Constipation, Functional Constipation
A Phase 2 Study to Evaluate Pharmacodynamics of YKP10811 in Patients With Chronic or Functional Constipation
This will be a single-center, randomized, parallel group, multiple dose administration, double-blind, placebo-controlled study to evaluate the effects of YKP10811 on gastric, small bowel, and colonic transit in patients with…
- Trial name
- NCT01523184
- Testing
- YKP10811 Drug Product Capsule
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- SK Life Science, Inc.
Functional Constipation
The Efficacy of a Probiotic for Functional Constipation (FC)
Investigate the effect of a probiotic (live bacteria) in individuals with functional constipation.
- Trial name
- SLOG (NCT06083311)
- Testing
- Probiotic
- Where
- Germany
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Functional Constipation (FC), Chronic Idiopathic Constipation (CIC)
A Study to Assess Adverse Events and Change in Symptoms With Linaclotide Versus Placebo in Pediatric Subjects, Ages 2 to 5 Years, With Functional Constipation
Functional constipation (FC) is a common healthcare problem in children of all ages, potentially due to genetic predisposition, inadequate fiber and fluid intake, and immobility.
- Trial name
- NCT05652205
- Testing
- Linaclotide
- Where
- 48 sites in United States, Bulgaria and 2 more
- Volunteers
- 123 people
- Sponsor
- AbbVie
Functional Constipation (FC)
The Beneficial Effect on the Bowel Function of a Food Supplement Based on Sea Buckthorn (Hippophae Rhamnoides L.) Extract in Subjects With Primary Functional Constipation
The study will aim to evaluate the efficacy and tolerability of a supplementation with Sea Buckthorn (Hippophae rhamnoides L.) at two different dosages for the management of the balance of intestinal function in subjects with…
- Trial name
- NCT07082673
- Testing
- Sea Buckthorn (Hippophae rhamnoides L.) botanical extract 500 mg., Sea buckthorn (Hippophae rhamnoides L.) 1500 mg.
- Where
- Italy
- Volunteers
- 135 people
- Sponsor
- ISTITUTO FARMOCHIMICO FITOTERAPICO: EPO SRL
Functional Constipation (FC)
Efficacy of Notrande Shuhuajun Probiotic Supplement on Lmproving Constipation in Preschool Children
The goal of this interventional study is to evaluate the effectiveness of Notrande Shuhuajun Probiotic Supplement intake on the improvement of functional constipation in preschool children (3-6 years old).
- Trial name
- NCT07002489
- Testing
- Nuotelande Shuhuajun Study Product
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Shandong Sibote Biotechnology Co., Ltd.
Irritable Bowel Syndrome With Constipation, Functional Constipation
Long-term Safety of Linaclotide in Pediatric Participants With FC or IBS-C
LIN-MD-66 is a Phase 3 open-label study with 24 weeks (Functional Constipation participants) or 52 weeks (Irritable bowel syndrome with constipation participants) of linaclotide exposure that will enroll pediatric participants…
- Trial name
- NCT04166058
- Testing
- Irritable Bowel Syndrome with Constipation (IBS-C) participants (LIN-MD-63 and LIN-MD-64 completers), Functional Constipation (FC) participants (LIN-MD-62 and LIN-MD-64 completers)
- Where
- 72 sites in United States, Canada and 2 more
- Volunteers
- 381 people
- Sponsor
- AbbVie
Functional Constipation (FC)
Fiber Nutritional Supplement for Management of Constipation During Pregnancy
This study aims to evaluate the effectiveness of a daily Fiber Nutritional Supplement (Materna® Opti fiber), containing partially hydrolyzed guar gum (PHGG) and vitamins C, D, zinc, and selenium, combined with nutritional…
- Trial name
- NCT07588633
- Testing
- fiber supplement (PHGG) with counselling for constipation management
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)