Clinical trials: Functional Disability, open to volunteers
Motor Delay, Infant Development
Wearable Sensor Toolkit for Infant Motor Development
The purpose of this study is to develop and test a fully automated, wireless sensor-based toolkit for infants that can capture early indicators (0-3 months) of motor deficits during activities of daily life and track motor…
- Conditions
- Motor Delay, Infant Development, Motor Development of Premature Infants, Motor Coordination or Function; Developmental Disorder
- Trial name
- NCT07866495
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Shirley Ryan AbilityLab
Low Back Pain
Effectiveness of Dry Needling in Patients With Chronic Nonspecific Low Back Pain
Low back pain is a major health problem that affects psychosocial, economical, functional and physical aspects of the patients' life.
- Trial name
- NCT05100381
- Testing
- dry needling
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Iran University of Medical Sciences
Stress, Psychological, Cognitive Decline
MindWalk Intervention for Older South Asian Caregivers of People With Cognitive Disabilities (CD)
Older South Asian family caregivers experience elevated psychological stress and limited physical activity (PA) due to caregiving responsibilities and additional factors such as lack of access to services, cultural/linguistic…
- Trial name
- NCT06002919
- Testing
- MindWalk Intervention
- Where
- 8 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Illinois Chicago
Young Children With Motor Disabilities
Inspiration From Eye-tracking Data: Investigating the Impact of Combining Specific Environmental Features and Power Mobility Training
This study has three main objectives. First, the investigators want to see how using a lightweight head-mounted eye tracker (HMET) can help to understand looking behavior, visual focus, and social interaction in toddlers with…
- Trial name
- NCT06928077
- Testing
- ROC-Stand training with specific environmental features, ROC-Stand training without specific environmental features, Conventional therapy
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Chang Gung Memorial Hospital
Dyslexia, Developmental, Reading
Enhancing Letter-Speech Sound Learning and Reading Network Activation With Transcranial Electrical Stimulation
This study investigates the effects of transcranial electrical stimulation (tES) on the brain and its potential to enhance reading-related learning.
- Conditions
- Dyslexia, Developmental, Reading, Dyslexia, Learning
- Trial name
- LexiStim (NCT07546292)
- Testing
- Transcranial random noise stimulation
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Silvia Brem
Chronic Low-back Pain (cLBP)
Combined and Aquatic Exercise in Chronic Low Back Pain
The goal of this randomized clinical trial is to evaluate the effects of a combined aquatic- and land-based exercise program, as well as an aquatic-exercise program, compared with a control group receiving home-based exercise, on…
- Trial name
- NCT07732595
- Testing
- Aquatic-exercise Program, Land-based Exercise Program, Home-based Exercise Program
- Where
- Portugal
- Volunteers
- 90 people
- Sponsor
- University of Beira Interior
Piriformis Syndrome
Comparative Effects of Post-Isometric Relaxation and Reciprocal Inhibition Techniques inPiriformis Syndrome
Piriformis Syndrome (PS) is a condition which is characterized by pain, numbness, and limited range of motion (ROM) due to compression or irritation of the sciatic nerve by the piriformis muscle.
- Trial name
- NCT07646314
- Testing
- Post isometrics Relaxation Techniques (PIR), Reciprocal Inhibition Technique
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Disability Evaluation, Recovery of Function
Effectiveness of VR Rehabilitation for People With Asymmetrical Gait Patterns
A randomized comparative study will be conducted to evaluate the rehabilitation process using a VR-based application versus conventional therapy in 40 patients (sample size determined using a sample size calculator).
- Conditions
- Disability Evaluation, Recovery of Function, Rehabilitation
- Trial name
- NCT07568821
- Testing
- Virtual Reality (VR) and Standard Rehabilitation, Standard Rehabilitation
- Volunteers
- 40 people
- Sponsor
- University of Rzeszow
Down Syndrome (Trisomy 21)
Vascular Function in Adults With Down Syndrome
Adults with Down syndrome (Ds) are often thought to have a lower risk of heart and blood vessel disease because they tend to have lower blood pressure (BP) and fewer heart attacks than people without Ds.
- Trial name
- VDS (NCT07630207)
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Episodic Migraine, Chronic Migraine
CGRP Inhibition, Autonomic Function, and Migraine
The purpose of this clinical study is to better understand the function of the autonomic nervous system in patients with migraine. We aim to understand whether the autonomic functions change depending on the migraine status (i.e.
- Trial name
- CGRP-1 (NCT04628429)
- Testing
- Erenumab, Galcanezumab, Fremanezumab
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Rheumatoid Arthritis (RA)
Evaluation of Functional Disability in Rheumatoid Arthritis Patients
Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune inflammatory disease that mainly affects the joints and periarticular soft tissues.
- Trial name
- NCT07801261
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sohag University
Lumbar Radiculopathy
Comparative Effects of Mulligan Bent Leg Raise Versus Spinal Mobilization With Leg Movement in Lumbar Radiculopathy
Lumbar radiculopathy is a spinal nerve root disorder often caused by lumbar disc herniation or compression, leading to radiating leg pain, restricted movement, and functional difficulties.
- Trial name
- NCT07726823
- Testing
- Mulligan Bent Leg Raise (MBLR), Spinal Mobilization With Leg Movement (SMWLM)
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Neck Pain, School Based Intervention
Pressure Biofeedback on Deep Cervical Flexor Muscles
This study aims to reduce mechanical neck pain and improve deep cervical flexor muscle endurance by using pressure biofeedback training for school educators to improve their job satisfaction and quality of life.
- Conditions
- Neck Pain, School Based Intervention, Functional Disabilities
- Trial name
- NCT07535879
- Testing
- Pressure Biofeedback Training, General Musculoskeletal Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Cervical Myofascial Pain Syndrome
Comparative Effect of Active Release Technique and Myofascial Release in Cervical Myofascial Syndrome
The aim of this randomized controlled trial is to find the comparative effect of Active Release Technique and Myofascial release, each combined with eye exercises, on asthenopia, sleep quality, stress, pain and functional…
- Trial name
- NCT07571655
- Testing
- Myofascial Release + Eye exercises, Active Release Technique + Eye exercises
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Kidney Transplant; Complications, Frailty
Effect of Home-based Training Program for Kidney Transplant Recipients (HOMETRAIN-KTR)
Does home-based training work in kidney transplant recipients with reduced physical function? The goal of this clinical trial is to learn if home-based training works to better physical function in adult kidney transplant…
- Conditions
- Kidney Transplant; Complications, Frailty, Physical Disability
- Trial name
- NCT06379009
- Testing
- Training
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Anterior Cruciate Ligament Injuries
Perturbation Training vs Functional Activities on Pain, ROM, Balance, and Function Post-ACL
Anterior cruciate ligament (ACL) injuries are among the most common and functionally disabling knee injuries, particularly in physically active individuals.
- Trial name
- NCT07642752
- Testing
- Perturbation Training Group, Task-Oriented Functional Activities Group, Control Group (Standard Rehabilitation Protocol)
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Alcohol Use Disorder, Mild Traumatic Brain Injury
rTMS Target Identification for Functional Disability in AUD+mTBI
The objectives of this VA Merit application are to identify a neural target unique to Veterans with co-occurring alcohol use disorder and mild traumatic brain injury (AUD+mTBI) and to test the efficacy of this target as a…
- Trial name
- rTMS-TARGET-ID (NCT04043442)
- Testing
- Magventure MagProX100 with MagOption stimulator and Magpro Cool Coil B65 A/P
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- VA Office of Research and Development
Deep Gluteal Syndrome
Neural Gliders With and Without ESWT for Deep Gluteal Syndrome
This study is a randomized controlled trial comparing Neural Gliders with and without Extracorporeal Shock Wave Therapy (ESWT) in patients with Deep Gluteal Syndrome.
- Trial name
- Neural Gliders (NCT07772674)
- Testing
- Group A= Neural Gliders with ESWT, Group B= Neural Gliders without ESWT
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- University of Management and Technology Sialkot Pakistan
Physical Disability, Physical Activity
Frame Running for Exercise and Participation for Children and Young People With Physical Disabilities
The goal of this quasi-experimental single-arm trial is to evaluate whether a structured Frame Running training program can improve functional ability, participation, and quality of life in children and young people with physical…
- Conditions
- Physical Disability, Physical Activity, Physical Function, Quality of Life
- Trial name
- FRAME-EX (NCT07543614)
- Testing
- Frame Running Training
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Odense University Hospital
Multiple Sclerosis, Healthy Controls Group - Age and Sex-matched
Measurement Properties of the Walking Adaptability Ladder Test and Foot Tap Test in Multiple Sclerosis
Walking and motor control impairments are among the most common manifestations experienced by people with multiple sclerosis (pwMS) and may already be present in individuals with mild disability.
- Trial name
- NCT07505355
- Where
- 4 sites in Belgium, Italy and 1 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasselt University