Clinical trials: Functional Disorder
Chronic Myeloproliferative Disorders, Cognitive/Functional Effects
Registry of Older Patients With Cancer
RATIONALE: Gathering information about older patients with cancer may help the study of cancer in the future. PURPOSE: This research study is gathering information from older patients with cancer into a registry.
- Conditions
- Chronic Myeloproliferative Disorders, Cognitive/Functional Effects, Leukemia, Lymphoma
- Trial name
- NCT01137825
- Where
- 7 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Functional Neurological Disorder
Dance/Movement Therapy for Functional Neurological Disorder
Building on evidence for somatic or physical interventions in functional neurological disorder (FND), the goal of this study is to test the feasibility of a structured dance/movement task in individuals with FND, and explore the…
- Trial name
- DMTforFND (NCT07378488)
- Testing
- Structured dance/movement, Physical exercise/body coordination
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- King's College London
Crohn Disease, Functional Gastrointestinal Disorders
Gastro-intestinal Biopotential Recorder by Means of Surface ELEctrodes
The goal of this clinical trial is to compare the gastro-intestinal biopotentials recorded with a homemade device using surface electrodes placed on the abdomen in healthy volunteers, Crohn's disease patients without fibrosis…
- Conditions
- Crohn Disease, Functional Gastrointestinal Disorders, Healthy
- Trial name
- GRELE (NCT06197334)
- Testing
- Gastro-intestinal biopotentials recording
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Respiration Disorder, Posture
Thoracic Mobility, Posture, Functional Capacity, and Respiratory Rate in Children Playing Wind Instruments
The aim of this study is to evaluate thoracic mobility, posture, functional capacity, and respiratory rate in children aged 8-14 years who play wind instruments and to compare these findings with those of their peers who do not…
- Conditions
- Respiration Disorder, Posture, Functional Capacity, Music
- Trial name
- WIND-KIDS (NCT07477535)
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Venous Thromboembolism (VTE), Exercise Therapy
Early Exercise-Based Rehabilitation in Patients Hospitalized for Acute Pulmonary Embolism
Up to half of patients with pulmonary embolism (PE) suffer from impaired quality of life, reduced physical capacity, and symptoms like shortness of breath even three months after diagnosis, despite standard treatment with…
- Conditions
- Venous Thromboembolism (VTE), Exercise Therapy, Quality of Life (QOL), Anxiety Depression
- Trial name
- RehabPE (NCT07143539)
- Testing
- Exercise-based rehabilitation program
- Where
- 6 sites in Switzerland
- Volunteers
- 160 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Functional Neurological Disorder, Convulsion, Non-Epileptic
Establishment of an Interdisciplinary Functional Neurological Disorder (FND) Treatment Program and Development of a Clinical Care Pathway for FND
The purpose of this study is to help providers develop an interdisciplinary treatment pathway for functional neurological disorder (FND) at University of Alabama at Birmingham (UAB), and will involve psychiatry, speech therapy…
- Conditions
- Functional Neurological Disorder, Convulsion, Non-Epileptic, Functional Seizure
- Trial name
- NCT06362161
- Where
- United States
- Volunteers
- 1,100 people
- Sponsor
- University of Alabama at Birmingham
Short Bowel Syndrome, Malabsorption Syndromes
Safety and Efficacy of Crofelemer in Adult Patients With Short Bowel Syndrome and Intestinal Failure (SBS-IF) Without Colon-in-continuity (CIC)
A 24-week, randomized, placebo-controlled, double-blind study to evaluate the efficacy, safety and tolerability of crofelemer in patients with Short Bowel Syndrome and Intestinal Failure (SBS-IF) without colon-in-continuity (CIC)…
- Conditions
- Short Bowel Syndrome, Malabsorption Syndromes, Short Gut Syndrome, Post-Op Complication
- Trial name
- CRO-SBS-IF (NCT06904872)
- Testing
- Crofelemer Powder for Oral Solution
- Where
- 8 sites in Germany, Italy
- Volunteers
- 18 people
- Sponsor
- Napo Therapeutics, S.p.A.
Functional Gastrointestinal Disorders (FGID)
Internet-delivered Psychological Treatment of Functional Gastrointestinal Disorders
Brief Summary Functional gastrointestinal disorders (FGID), including irritable bowel syndrome (IBS), are common conditions characterized by recurrent gastrointestinal symptoms that cannot be fully explained by structural…
- Trial name
- NCT07636122
- Testing
- I-CBT
- Volunteers
- 30 people
- Sponsor
- University of Aarhus
Cerebral Palsy (CP), Spastic Quadriplegia
Impact of Task-Specific Electrical Stimulation on Upper Limb Functional Motor Skills in Children With Spastic Quadriplegia
Cerebral palsy is a non-progressive lesion of the brain occurring before 2 years of age resulting in disorders of posture and movement.( Ostensjo S, 2004)( Keles MN, 2018) .
- Conditions
- Cerebral Palsy (CP), Spastic Quadriplegia, Upper Limb Function, Functional Motor Disorder
- Trial name
- NCT07631390
- Testing
- The Chattanooga Continuum™, Designed Physical therapy program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kafrelsheikh University
Functional Gastrointestinal Disorders
Functionally Enhanced Limosilactobacillus Reuteri Probiotic Preparation in Elderly Patients With Functional Bowel Disorders
This is a single-center, open-label, single-arm interventional study designed to evaluate the effects of a functionally enhanced Limosilactobacillus reuteri probiotic preparation on intestinal immunity, gut microbiota balance…
- Trial name
- NCT07624656
- Testing
- Functionally Enhanced Limosilactobacillus reuteri Probiotic Preparation
- Volunteers
- 30 people
- Sponsor
- Maanshan Shiqiye Hospital
Depression - Major Depressive Disorder, Bipolar Disorder (BD)
Flumazenil for Benzodiazepine Reversal in Electroconvulsive Therapy
The goal of this study is to investigate whether administering flumazenil to reverse the effects of benzodiazepines and/or zopiclone during electroconvulsive therapy (ECT) can help reduce cognitive side effects without…
- Conditions
- Depression - Major Depressive Disorder, Bipolar Disorder (BD), Functional Magnetic Resonance Imaging (fMRI), Cognition
- Trial name
- FLEET (NCT07619092)
- Testing
- Flumazenil, Electroconvulsive therapy (ECT)
- Where
- Denmark
- Volunteers
- 145 people
- Sponsor
- Anders Jørgensen
Functional Gastrointestinal Disorder
Long Term Follow up on Functional Gastrointestinal Disorder (FGID)
Long term prognosis and risk factors in functional gastrointestinal disorder (FGID) is largely unknown. The investigators plan to retrospectively analyse a cohort of children who were referred to the Pediatric Clinic due to…
- Trial name
- LUFT (NCT02689648)
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Umeå University
Functional Neurological Disorder
Feasibility of Remotely Measured Activity Behavior for Individuals With Functional Neurologic Disorder
This study evaluates whether remotely measured daily activity behavior, captured through a thigh-worn accelerometer, can serve as a reliable and ecologically valid indicator of symptom impact in individuals with Functional…
- Trial name
- NCT07478666
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Functional Neurological Disorder, Functional Movement Disorder
The Effect of Psychoeducational Diagnosis Communication on Perception of Illness, Satisfaction, and Behavioral Intentions Among Patients With Functional Neurological Movement Disorders
Functional neurological movement disorders are common conditions that can lead to significant limitations in daily life. They result from a functional disorder in the brain.
- Trial name
- NCT07588282
- Testing
- Psychoeducational communication guide for first-diagnosis of FND
- Where
- Austria
- Volunteers
- 35 people
- Sponsor
- Medical University of Graz
Functional Movement Disorder, Functional Neurological Disorder
Tremor Retrainer Software Application for Functional Tremor
The purpose of this clinical trial is to learn about the Tremor Retrainer smartphone application and Simplified Functional Movement Disorder Rating Scale in patients with functional tremor.
- Conditions
- Functional Movement Disorder, Functional Neurological Disorder, Functional Neurological Symptom Disorder
- Trial name
- NCT06257069
- Testing
- Tremor Retrainer Smartphone Application
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Functional Gastrointestinal Disorders
NLP to Aid in the Evaluation and Diagnosis of FGIDs
The study has two arms, where the same natural language processing (NLP) and probabilistic graphical modeling technology will be utilized on patients' report of symptoms in both arms.
- Trial name
- NCT05501028
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Massachusetts General Hospital
Autism, Depression
Adapting BA for Minimally Verbal Autistic Adults
The present study aims to adapt and evaluate the feasibility of the BeatIt-2 behavioral activation intervention for people with intellectual disabilities and low mood to be implemented with minimally verbal autistic individuals.
- Conditions
- Autism, Depression, Autism Spectrum Disorder With Impaired Functional Language, Autism Spectrum Disorder
- Trial name
- NCT06064422
- Testing
- BeatIt-MV
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rutgers, The State University of New Jersey
Dyspepsia, Functional Gastrointestinal Disorders
Traditional Dietary Advice Versus Low FODMAP Diet in Postprandial Functional Dyspepsia
Functional dyspepsia is common, affecting 7.2% of the global population, and associated with substantial health impairment. Almost 80% of patients with functional dyspepsia report meal-related symptoms and are classified as…
- Trial name
- NCT05810168
- Testing
- Dietary modifications
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Anxiety Disorder, Cognitive/Functional Effects
Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer
RATIONALE: Participating in a physical activity program designed to increase free time physical activity and receiving written health education materials may influence the chance of cancer recurring as well as impact on physical…
- Conditions
- Anxiety Disorder, Cognitive/Functional Effects, Colorectal Cancer, Depression
- Trial name
- CHALLENGE (NCT00819208)
- Testing
- exercise intervention, counseling intervention, educational intervention
- Where
- 47 sites in United States, Australia and 4 more
- Volunteers
- 889 people
- Sponsor
- Canadian Cancer Trials Group
Chronic Pain, Pelvic Pain
Vibratory Stimulation for the Treatment of Chronic Pain
The purpose of this study is to perform a first in man study with VCR stimulation of the belly and back for patients with chronic pain conditions including pelvic pain, functional abdominal pain, or low back pain.
- Conditions
- Chronic Pain, Pelvic Pain, Functional Abdominal Pain Syndrome, Low Back Pain
- Trial name
- NCT04069572
- Testing
- Vibrotactile Stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University