Clinical trials: Functional Dysphonia
Dysphonia
Comprehensive Voice Rehabilitation Program Compared With Vocal Function Exercises
The purpose of this study is to evaluate the effectiveness and safety of the Comprehensive Voice Rehabilitation Program compared with Vocal Function Exercises in behavioral dysphonia.
- Trial name
- Voicetherapy (NCT02409758)
- Testing
- Voice therapy
- Volunteers
- 106 people
- Sponsor
- Federal University of São Paulo
Gastroesophageal Reflux, Functional Dysphonia
Assessment on Effects of Tongjiang Granule in Treating Nonerosive Reflux Disease Overlapping Epigastric Pain Syndrome
Overlapping gastrointestinal symptoms of functional gastrointestinal diseases (FGIDs) is an internationally recognized problem in modern medical diagnosis and treatment.
- Trial name
- NCT05312463
- Testing
- Tongjiang granule, Tongjiang granule simulant
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Spasmodic Dysphonia, Focal Dystonia
Role of Neurotransmission and Functional CNS Networks in Spasmodic Dysphonia
This study will examine how the brain controls speech in patients with spasmodic dysphonia, a voice disorder that involves involuntary spasms of muscles in the larynx (voice box), causing breaks in speech.
- Trial name
- NCT00713414
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Improved Healing of Scarred Vocal Folds, Improved Vocal Fold Status
Pilot Study of Stem Cell Treatment of Patients With Vocal Fold Scarring
This is a pilot-study of 16 selected Swedish patients which all have severe hoarseness or aphonia due to vocal fold scarring (from previous surgery, radiation therapy, inflammation or possibly hereditary).
- Conditions
- Improved Healing of Scarred Vocal Folds, Improved Vocal Fold Status, Improved Vocal Fold Function
- Trial name
- NCT01981330
- Testing
- aMSC, aMSC+hyaluronan gel
- Where
- Sweden
- Volunteers
- 16 people
- Sponsor
- Karolinska University Hospital
Crohn Disease, Ulcerative Colitis
Safety and Efficacy of Fecal Microbiota Transplantation
The gut microbiota is critical to health and functions with a level of complexity comparable to that of an organ system. Dysbiosis, or alterations of this gut microbiota ecology, have been implicated in a number of disease…
- Conditions
- Crohn Disease, Ulcerative Colitis, Celiac Disease, Irritable Bowel Syndrome
- Trial name
- NCT04014413
- Testing
- Fecal Microbiota Transplantation
- Where
- Hong Kong
- Volunteers
- 450 people
- Sponsor
- Chinese University of Hong Kong
Laryngeal Dystonia, Focal Dystonia
Effects of Neuromodulation in Laryngeal Dystonia
Laryngeal dystonia (LD) causes excessive vocal fold abduction (opening) or adduction (closing) leading to decreased voice quality, job prospects, self-worth and quality of life.
- Trial name
- NCT05095740
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Functional Dysphonia
A Trial of Transcranial Magnetic Stimulation in the Treatment of Functional Dyspepsia
The goal of this clinical trial is to learn if theta burst stimulation (TBS), a form of Transcranial Magnetic Stimulation (TMS), can treat functional dyspepsia (FD) and compare its effectiveness against conventional drug…
- Trial name
- NCT06559748
- Testing
- transcranial magnetic thetaburst stimulation （TBS）
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Hoarseness, Dysphonia
A Study of Local Administration of Autologous Mesenchymal Stromal Cells in Dysphonic Patients With Vocal Fold Scarring
The overall aim of the project is to develop a new method for treatment of untreatable severe hoarseness due to vocal fold scarring by local injection of autologous mesenchymal stromal cells (MSC).
- Conditions
- Hoarseness, Dysphonia, Aphonia, Vocal Fold Scar
- Trial name
- NCT04290182
- Testing
- MSC-KI-PL-204
- Where
- Sweden
- Volunteers
- 9 people
- Sponsor
- Karolinska University Hospital