Clinical trials: Functional Electrical Stimulation
Stroke
Effects of Device-assisted Practice of ADL on Arm/Hand Recovery in Individuals With Moderate to Severe Stroke
A large number of post-stroke survivors cannot functionally use their paretic upper extremity (UE). This study therefore investigates effects of device-assisted practice of activities of daily living (ADL) in a close-to-normal…
- Trial name
- NCT04077073
- Testing
- ReIn-Hand, Robot
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Northwestern University
Stroke, Acute, Stroke
Treatments for Recovery of Hand Function in Acute Stroke Survivors
Impaired hand function is one of the most frequently persisting consequences of stroke. The purpose of this study is to investigate whether two different types of treatment improve recovery of hand function after stroke.
- Conditions
- Stroke, Acute, Stroke, Hemiparesis, Hemiplegia
- Trial name
- NCT00565045
- Testing
- Neuromuscular electrical stimulator
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- MetroHealth Medical Center
Healthy, Brain Stimulation
Effects of Transcranial Electrical Stimulation on Task Performance in Healthy Adults
The objective of this randomized, double-blind, sham-controlled, crossover study is to evaluate the effects of transcranial electrical stimulation (tES) on complex cognitive task performance in healthy adult volunteers.
- Conditions
- Healthy, Brain Stimulation, Transcranial Direct Current Stimulation (tDCS), Cognition
- Trial name
- BRAIN-STIM (NCT06995560)
- Testing
- Active Transcranial Electrical Stimulation
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Irritable Bowel Syndrome, Abdominal Pain
Percutaneous Electrical Nerve Field Stimulation for Adults With Irritable Bowel Syndrome
This is a prospective, double-blind, randomized, sham-controlled pilot study evaluating the efficacy of percutaneous electrical nerve field stimulation for the treatment of adult patients with irritable bowel syndrome (IBS).
- Conditions
- Irritable Bowel Syndrome, Abdominal Pain, Autonomic Nervous System Imbalance
- Trial name
- NCT04428619
- Testing
- Peripheral Electrical Nerve Field Stimulation (PENFS) Device
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, Los Angeles
Anesthesia, Pain
Memory & Conditioning Under Anesthesia
The purpose of this study is to determine the effects of pain on long-term memory and conditioned physiologic responses in the presence and absence of distinct intravenous anesthetics.
- Trial name
- MCA (NCT04062123)
- Testing
- Dexmedetomidine, Propofol, Fentanyl
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Keith M Vogt
Transcranial Electrical Stimulation
Transcranial Electrostimulation and Obstructive Sleep Apnea Surgery
Postoperative pain after major surgery for obstructive sleep apnea (OSA), such as palatopharyngoplasty (PPP) and maxillomandibular advancement (MMA) is moderate-to-severe, and may persist for weeks.
- Trial name
- NCT03735004
- Testing
- Transcranial electrostimulation (TES)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Stroke
Noninvasive Spinal Stimulation in Stroke
This is a randomized control trial that will evaluate the effectiveness of transcutaneous (non-invasive) spinal cord stimulation on gait and balance function for individuals with hemiplegia due to stroke.
- Trial name
- NCT03714282
- Testing
- Noninvasive spinal stimulation with gait training, Conventional gait training
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Combined Brain and Peripheral Nerve Stimulation for Stroke
Cerebrovascular disease is a major cause of disability worldwide. The catastrophic burden of stroke is more dramatic in low- and middle- income countries, and the scarcity of evidence-based rehabilitation interventions represents…
- Trial name
- NCT01907737
- Testing
- Active tDCS, Active PNS
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- University of Sao Paulo General Hospital
Dysphagia
Functional Electrical Stimulation in Irradiated Nasopharyngeal Carcinoma (NPC)
The purpose of this study is to determine whether functional electrical stimulation is effective in the treatment of dysphagia due to nasopharyngeal cancer post radiotherapy
- Trial name
- NCT00815087
- Testing
- Functional electrical stimulation, Exercise home program
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Spinal Cord Injury
Patterned Functional Electrical Stimulation (FES) Ergometry of Arm and Shoulder in Individuals With Spinal Cord Injury
To determine whether functional electrical stimulation (FES) promotes neurological and physical recovery in patients with spinal cord injury (SCI).
- Trial name
- NCT01005615
- Testing
- Non-FES Upper Extremity Exercise, RT300-SLSA, from Restorative Therapies, Inc.
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Spinal Cord Injuries, Tetraplegia
Restoring High Dimensional Hand Function to Persons With Chronic High Tetraplegia
This study is for people who have a paralyzed arm and hand from a spinal cord injury, who have also received a recording electrode array in the brain as part of the BrainGate study.
- Conditions
- Spinal Cord Injuries, Tetraplegia, Quadriplegia
- Trial name
- NCT03482310
- Testing
- Using the Neuroport cortical recording array to determine the desired grasp pattern for a functional electrical stimulation (FES) system
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injury, Acute, Neurogenic Bladder
Sacral Nerve Stimulation in Improving Bladder Function After Acute Traumatic Spinal Cord Injury
The purpose of this study is to see what effects sacral neuromodulation has on bladder function and quality of life in patients with acute spinal cord injury.
- Conditions
- Spinal Cord Injury, Acute, Neurogenic Bladder, Incontinence, Urinary Tract Infections
- Trial name
- NCT03083366
- Testing
- PrimeAdvanced Surescan 97702 Neurostimulator - Medtronic (Minneapolis, MN)
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- University of Utah
Multiple Sclerosis
Effects of Functional Electrical Stimulation Cycling Versus Cycling Only on Walking and Quality of Life in MS
This study will seek to determine the benefits that FES-LE cycling has over cycling alone on walking performance and quality of life in people with multiple sclerosis.
- Trial name
- MSCycling (NCT02606604)
- Testing
- RT 300: Lower Extremity Cycling
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stony Brook University
Stroke, Hemiplegia
Functional Electrical Stimulation for Footdrop in Hemiparesis
The objective of this research is to determine if electrical stimulation can improve the strength and coordination of the lower limb muscles, and the walking ability of stroke survivors.
- Trial name
- NCT00148343
- Testing
- Odstock Dropped-Foot Stimulator (ODFS), Conventional Standard of Care, Traditional Physical Therapy Treatment
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- MetroHealth Medical Center
Diabetes Mellitus, Obesity
Exercise to Reduce Obesity in Spinal Cord Injury
The purpose of this proposal was to evaluate and compare the health benefits of using upper extremity exercise versus functional electrical stimulation for lower extremity exercise.
- Conditions
- Diabetes Mellitus, Obesity, Paraplegia, Quadriplegia
- Trial name
- NCT00270855
- Testing
- Arm Crank Ergometry, FES Cycle Ergometer
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Office of Research and Development
Anesthesia, Pain
Neural Correlates of Lidocaine Analgesia
The purpose of this study is to characterize the effects of intravenous lidocaine on pain processing and cognitive function. Functional magnetic resonance imaging will be used to identify the neural correlates of these phenomena.
- Trial name
- NeuCLA (NCT05501600)
- Testing
- Peripheral Nerve Stimulation, Lidocaine IV
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Keith M Vogt
Foot Drop
Augmenting Gait in a Population Exhibiting Foot Drop With Adaptive Functional Electrical Stimulation
The objective of this study is to investigate the effects of personalized, adaptive, current-steering functional electrical stimulation (FES) of the lower leg to improve gait in people with foot drop.
- Trial name
- NCT05346640
- Testing
- Cionic Neural Sleeve
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Cionic, Inc.
Osteoarthritis, Osteoarthritis, Knee
A 12-Week Home-Based Electrical Stimulation Program for Strength in Adults With Knee Osteoarthritis
The purpose of this research is to investigate if a 12-week program of stimulation assisted activities can combat disuse atrophy for individuals diagnosed with knee osteoarthritis (KOA).
- Trial name
- NCT05765435
- Testing
- 12-week exercise and walking program, NMES, FES
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Cionic, Inc.
Stroke, Upper Extremity Paresis
Therapies for Recovery of Hand Function After Stroke
After a stroke, it is very common to lose the ability to open the affected hand. The purpose of this study is to compare the effects of three different therapies on recovery of hand function after stroke and determine if any one…
- Conditions
- Stroke, Upper Extremity Paresis, Hemiplegia
- Trial name
- NCT03574623
- Testing
- Electrical Stimulator, Occupational Therapy
- Where
- 4 sites in United States
- Volunteers
- 132 people
- Sponsor
- MetroHealth Medical Center
Multiple Sclerosis
Impact of Direct Current Electrical Stimulation on Spasticity Levels and Functional Muscle Use in MS
In an individual with MS the central nervous system (CNS) is over-protective and causes the threshold for stretch reflex and muscle tightness to be set lower than normal.
- Trial name
- NCT04942938
- Testing
- Neubie
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- CommonSpirit Health