Clinical trials: Functional Immune Response
HIV, HIV/AIDS
Reducing Proviral HIV DNA With Interferon-a
The purpose of this study is to determine if treatment with pegylated interferon alpha 2b (peg-IFN-α2b) will reduce the amount of integrated HIV DNA in peripheral blood cells and tissues of individuals with chronic HIV infection…
- Trial name
- BEAT-HIV (NCT02227277)
- Testing
- Peg-IFN-α2b
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- The Wistar Institute
Glycemic and Insulinemic Response, Type 1 Diabetes (T1D)
Glycemic Response to Carbob-Enriched Pasta in Healthy and With Type 1 Diabetes People
Carob (Ceratonia siliqua) is a fruit traditionally used in various Mediterranean countries for the preparation of sweets and beverages.
- Trial name
- GR-CEP (NCT06994403)
- Testing
- Durum wheat pasta enriched with carob flour, Standard durum wheat pasta, White bread reference meal
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federico II University
Immune Response
The Immune Function Intervention Trial
The purpose of the study is to examine whether cardiovascular exercise training improves immune responses to vaccination in previously sedentary older adults.
- Trial name
- ImFIT (NCT00548990)
- Testing
- cardiovascular exercise training, flexibility/balance control
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Adjuvant Chemotherapy, Colon Cancer
Modulation of Immune Response by Oral Zinc Supplementation in Chemotherapy for Colon Cancer
In leukocytes of patients undergoing adjuvant chemotherapy for colon cancer treatment: a)identify genes modulated by oral supplementation of zinc; b) evaluate the effects of oral zinc supplementation on humoral immunity and…
- Conditions
- Adjuvant Chemotherapy, Colon Cancer, Immunity
- Trial name
- NCT01261962
- Testing
- zinc
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Lymphoma
MRI Compared to PET/CT for Staging and Treatment Response in Lymphoma
The lymph nodes or masses,positron emission tomography/computed tomography (PET/CT) standardized uptake values(SUV) results, whole body magnetic resonance imaging(MRI) intravoxel incoherent motion(IVIM) sequence D, D*, f values…
- Trial name
- NCT02733887
- Testing
- magnetic resonance imaging, positron emission tomography/computed tomography, fludeoxyglucose F 18
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Guangxi Medical University
Type 1 Diabetes, Type 2 Diabetes
Glucotoxicity and Acute Exercise
Experimental hyperglycemia (5 hours) will be induced via a constant- or fluctuating-rate glucose infusion to establish different patterns of glycemia in healthy individuals.
- Trial name
- NCT01771614
- Testing
- Exercise, Hyperglycemia
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
HIV Infections
Quality of Life, Depression and Sexual Function in Men Living With HIV
This observational case-control study evaluates quality of life, depressive symptoms, and sexual function in heterosexual men living with HIV who are receiving effective combination antiretroviral therapy and have achieved…
- Trial name
- NCT07376239
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Obesity, Overweight
Long-term Effects of Arabinoxylans on Intestinal Barrier Function
The higher prevalence of overweight and obesity among the population contributes to increased incidences of chronic metabolic diseases.
- Trial name
- NCT01877044
- Testing
- NAXUS
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Stress (Psychology)
Effects of Mechanical Massage on Sleep Quality, Immunity, and Stress
This bicentric, randomized, single-blind clinical investigation aims to evaluate the effects of a multisession mechanical massage (endermologie) program on sleep quality, immune function, and stress levels in individuals…
- Trial name
- NCT07811284
- Testing
- Mechanized Massage (LPG Cellu M6 Alliance)
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bescored