Clinical trials: Functional Iron Deficiency, open to volunteers
Iron-Deficiency Anemia, Neurobehavioral Manifestations
Impact of Iron Deficiency Anemia on Neurobehavioral and Cognitive Development in Children Aged 6 to 24 Months
The goal of this observational study is to explore the relationship between iron-deficiency anemia and neurobehavioral development in children aged 6-24 months.
- Conditions
- Iron-Deficiency Anemia, Neurobehavioral Manifestations, Growth Disorders, Nutritional Status
- Trial name
- NCT06662045
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Pingshan District Maternal & Child Healthcare Hospital of Shenzhen
Heart Failure, Systolic, Iron Deficiencies
IV Iron and SGLT2 Inhibitor on Ventricular Function and Myocardial Iron Content in Heart Failure With Iron Deficiency
Background. Treatment with intravenous iron has been shown to improve symptoms, functional capacity, and quality of life in patients with heart failure with reduced ejection fraction (HFrEF) and iron deficiency.
- Trial name
- COMBINED-HF (NCT06434025)
- Testing
- Iron Carboxymaltose, Dapagliflozin 10mg Tab
- Where
- Brazil
- Volunteers
- 99 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Iron Deficiency
Effects of Iron Supplementation on Skeletal Muscle Properties in Females With Suboptimal Iron Storage
The goal of this clinical trial is to learn whether oral iron supplementation will increase skeletal muscle iron storage and its effects on exercise capacity in females with suboptimal iron status.
- Trial name
- MyoIRON (NCT07084298)
- Testing
- Oral iron supplement
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Iron Deficiency Anemia Treatment, Iron Deficiency
How Does Perimenopausal Menorrhagia Affect Women's Quality of Life and Cognitive Function?
The goal of this clinical trial is to investigate how iron status and heavy bleeding during the menopausal transition affect women's cognitive function and quality of life.
- Conditions
- Iron Deficiency Anemia Treatment, Iron Deficiency, Iron Deficiency (Without Anemia)
- Trial name
- MENO (NCT06798584)
- Testing
- FeoSol Original Iron Supplement Tablets, 21st Century Gelatin Capsules
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Purdue University
Heart Failure With Preserved Ejection Fraction, Iron Deficiency
IV Iron Therapy for Older Adults With Heart Failure With Preserved Ejection Fraction and Iron Deficiency
This randomized, double-blind, placebo-controlled clinical trial evaluates intravenous ferric derisomaltose in older adults with HFpEF and iron deficiency.
- Trial name
- INFUSE-HFpEF (NCT07686692)
- Testing
- Ferric derisomaltose
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duke University
Iron Deficiency Anemia
Impact of Intravenous Iron on Musculoskeletal Function in Older Adults
Anaemia is a risk factor for functional decline and frailty in older adults including decreased physical performance and muscle strength, increased hospitalisation risk and mortality, falls, and poorer recovery from activities of…
- Trial name
- FERIDA (NCT05708170)
- Testing
- Ferinject, Ferrous Sulfate 200 MG
- Volunteers
- 100 people
- Sponsor
- Liverpool Hope University
Aortic Valve Stenosis, Iron Deficiency
Iron Infusion in Patients Undergoing Transcatheter Aortic Valve Implantation
The aim of the open-label, randomized controlled superiority IRON TAVI trial is to investigate whether intravenous iron therapy (ferric carboxymaltose) improves Health-Related Quality of Life (HRQOL) in patients with severe…
- Conditions
- Aortic Valve Stenosis, Iron Deficiency, TAVI(Transcatheter Aortic Valve Implantation), Cardiovascular Diseases
- Trial name
- IRON TAVI (NCT07370688)
- Testing
- Intravenous ferric carboxymaltose
- Where
- Netherlands
- Volunteers
- 402 people
- Sponsor
- Erasmus Medical Center
Bleeding Disorders, Iron
Impact of IV Iron on Bleeding Symptoms in Iron Deficient Patients With Inherited Bleeding Disorders
This is a prospective, single-arm, single-center observational study evaluating the impact of intravenous (IV) iron replacement in patients with inherited bleeding disorders and iron deficiency (ferritin <50ng/dL).
- Conditions
- Bleeding Disorders, Iron, Platelet, Bleeding
- Trial name
- IRON-BD (NCT07083583)
- Testing
- IV Iron (standard of care)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Nicoletta C Machin
Pulmonary Hypertension, Iron Deficiency
The Impact of IV Iron on Exercise Capacity and Quality of Life in Pulmonary Hypertension
Pulmonary hypertension (PH) is a condition characterized by elevated blood pressure in the pulmonary arteries. This leads to symptoms such as shortness of breath and a significantly reduced exercise capacity, resulting in a very…
- Trial name
- IRON-PH (NCT07359599)
- Testing
- Ferric Carboxymaltose (FCM), Sodium Chloride (NaCl) 0.9 %
- Where
- 7 sites in Belgium
- Volunteers
- 306 people
- Sponsor
- Ziekenhuis Oost-Limburg
Chronic Heart Failure, Iron Deficiency, Latent
The Prevalence of Iron Deficiency and the Effectiveness of Ferinject® in Patients With HFpEF (ID-HFpEF)
Observational cohort randomized controlled study to study the influence of correction of ID by intravenous injection of ferric carboxymaltose (Ferinject®) on quality of life indicators, functional status in a cohort of patients…
- Trial name
- ID-HFpEF (NCT05793996)
- Testing
- Ferinject, Diet therapy
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences