Clinical trials: Functional Knee Pain
Knee Discomfort, Joint Pain
Turmeric Efficacy for Mobility and Joint Function
The objective of the study is to test the capacity of a 12-weeks Turmipure GOLD® supplementation to reduce joint discomfort.
- Trial name
- T-MOTION (NCT04506411)
- Testing
- Turmipure GOLD®, Turmeric rhizome PE 95% curcuminoids
- Where
- 8 sites in Croatia, Slovenia
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Givaudan France Naturals
Pain, Physical Function
Osteoarthritis Outcomes in Different Ages
We aim to study if there are differences in outcomes between different age groups for persons with knee or hip osteoarthritis during treatment in digitally delivered exercise and education treatment.
- Conditions
- Pain, Physical Function, Age
- Trial name
- NCT05208463
- Testing
- Joint Academy
- Where
- Sweden
- Volunteers
- 14,610 people
- Sponsor
- Joint Academy
Osteoarthritis
An Investigation of ReNu™ Knee Injection in Patients With Osteoarthritis
This is a Prospective, Randomized study evaluating the efficacy of ReNu for the treatment of Kellgren-Lawrence grade 2 or 3 osteoarthritis.
- Trial name
- NCT02318511
- Testing
- Knee injection, ReNu amniotic allograft, Hyaluronic Acid
- Where
- 12 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NuTech Medical, Inc
Osteoarthritis, Knee
Robotic-Assisted Versus Conventional Total Knee Arthroplasty With Virtual Home-Based Rehabilitation
The goal of this clinical trial is to learn whether robotic-assisted total knee replacement improves recovery compared with conventional total knee replacement in adults with knee osteoarthritis when both groups follow the same…
- Trial name
- R-TKR VCare (NCT07716267)
- Testing
- Robotic-assisted Total Knee Arthroplasty, Conventional Total Knee Arthroplasty, Hybrid Virtually-Assisted Peri-operative Rehabilitation Program
- Volunteers
- 60 people
- Sponsor
- Mark Hurworth
Knee Discomfort, Pain Physical Activity
Polyherbal Capsule Formulation for Joint Health
This is a multicenter, randomized, double-blind, placebo-controlled, study in subjects with exercise-related knee pain/discomfort to determine the efficacy of a polyherbal capsule compared to placebo capsule in improving exercise…
- Trial name
- NCT02157701
- Testing
- Polyherbal capsule
- Where
- 5 sites in United States
- Volunteers
- 108 people
- Sponsor
- NewChapter, Inc.
Osteoarthritis, Knee
A Telehealth Study of a Wearable Electroceutical & Sports Sleeve for Knee Osteoarthritis Pain Relief & Improved Function
The purpose of this telemedicine 24-person open-label study is to evaluate the safety and usability of a proprietary wearable microcurrent electroceutical (a device that delivers micro-ampere electronic pulses) made by Healables…
- Trial name
- HEAL01WMCOA1 (NCT04938271)
- Testing
- HEAL-122 microcurrent electroceutical with e-textile sports knee sleeve
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Healables Ltd.
Osteoarthritis of Knee, Edema
Microcurrent Stimulation Reduces Post-Operative Swelling and Healing Time Following Knee Replacement Surgery
The purpose of this study is to determine if patients undergoing a total knee arthroplasty (TKA) experience a clinically significant reduction in healing time when treated post operatively with a specific form of micro and…
- Conditions
- Osteoarthritis of Knee, Edema, Wounds and Injuries
- Trial name
- NCT02623660
- Testing
- ODIN1, Standard Care, Diagnostic Device Testing
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bioelectric Research Corporation
Osteoarthritis of the Knee, Degenerative Osteoarthritis
Platelet-Rich Plasma and the Effects of NSAIDs on Pain and Functional Scores in Knee Osteoarthritis
The primary research purpose is to determine if the use of a drug therapy intervention (each study participant will be randomly assigned to receive one of 3 study medications which will be blinded from everyone, including the…
- Conditions
- Osteoarthritis of the Knee, Degenerative Osteoarthritis, Knee Pain Chronic
- Trial name
- PRPNSAIDsKOA (NCT05742763)
- Testing
- Ibuprofen and PRP, Acetaminophen and PRP
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- QC Kinetix LLC
Pain
Pivotal Study on the NOVABLOC System for Patients Undergoing Primary Total Knee Arthroplasty
Multi-center, randomized, blinded, sham-controlled study to determin the safety and efficacy of the NOVABLOC system on post-operative pain in patients undergoing TKA procedures.
- Trial name
- NOVABLOC-TKA (NCT07191067)
- Testing
- Percutaneous radiofrequency electrical nerve stimulation, Non-therapeutic stimulation
- Where
- 5 sites in United States
- Volunteers
- 123 people
- Sponsor
- Synaptrix, Inc.
Anterior Cruciate Ligament Reconstruction
Study of RNS60 on Pain and Function After Knee Anterior Cruciate Ligament Surgery
The purpose of this study is to see if use of RNS60 during ACL reconstruction surgery decreases pain and improves functional capacity post-operation.
- Trial name
- NCT01922427
- Testing
- RNS60
- Sponsor
- Revalesio Corporation
Severe Osteoarthritis of the Knee
Study of Ampion for the Treatment of Pain and Function in Patients With Severe Osteoarthritis of the Knee.
The purpose of this study is to confirm the safety and efficacy of Ampion for the treatment of pain and function in patients with severe osteoarthritis of the knee.
- Trial name
- NCT03988023
- Testing
- Ampion, Saline
- Where
- United States
- Volunteers
- 1,043 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Osteoarthritis, Pain
Celebrex Total Knee Arthroplasty Study
This study will investigate the benefits of administering celecoxib (Celebrex), a selective cyclooxygenase -2 (COX-2) inhibitor, in treating osteoarthritis (OA) subjects undergoing elective unilateral primary total knee…
- Trial name
- NCT00359151
- Testing
- Celecoxib
- Where
- 7 sites in United States
- Volunteers
- 22 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Knee Arthritis, Knee Osteoarthritis
Gold Factor on Knee Joint Health and Function
The purpose of this clinical study was to determine whether gold nanoparticles (AuNP) supplement holds clinical value in improving joint health, function, and quality of life for arthritis patients.
- Conditions
- Knee Arthritis, Knee Osteoarthritis, Knee Pain Chronic, Knee Discomfort
- Trial name
- NCT05347602
- Testing
- Gold Factor (Gold Nanoparticles, AuNPs)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- 4Life Research, LLC
Chronic Osteoarthritis
OXN PR Compared to OxyPR to Demonstrate Non-inferiority in Pain & Locomotor Function & Improvement in Symptoms of Constipation in OA Subjects
The primary objectives are to demonstrate that the treatment with OXN PR tablets is non-inferior to the treatment with OxyPR with regards to analgesic efficacy and locomotor function.
- Trial name
- NCT00902837
- Testing
- Oxycodone naloxone prolonged release tablets (OXN), oxycodone prolonged release tablet, oxycodone naloxone tablet
- Where
- 36 sites in Belgium, Czechia and 4 more
- Volunteers
- 181 people
- Sponsor
- Mundipharma Research GmbH & Co KG