Clinical trials: Functional Motor Disorder
Stroke
Repetitive Nerve Stimulation to Improve Recovery After Stroke
Upper limb paresis is the most common type of post-stroke neurological impairment and a major cause of functional disability. Repetitive peripheral sensory stimulation (RPSS) is a novel strategy to improve upper limb motor…
- Trial name
- RESTORES (NCT03956407)
- Testing
- Suprathreshold repetitive peripheral sensory stimulation, Subthreshold repetitive sensory stimulation
- Where
- Brazil
- Volunteers
- 51 people
- Sponsor
- Hospital Israelita Albert Einstein
Sickle Cell Anemia, Muscle Dysfunction
Physical Rehabilitation in Sickle Cell Anemia
Sickle cell anemia (SCA) is one of the most neglected diseases worldwide, according to the World Health Organization. In the adult population with SCA, the systemic effects of the disease, such as respiratory and peripheral…
- Conditions
- Sickle Cell Anemia, Muscle Dysfunction, Quality of Life, Physical Activity
- Trial name
- NCT04705792
- Testing
- Physical activity
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Centro Universitário Augusto Motta
Sarcopenia, Aging
Dual-benefits of Aerobic and Resistance Training
This study evaluates the effect of three different exercise strategies on physical function in older adults. Participants will be randomly assigned to one of three exercise groups: resistance training, moderate-intensity…
- Conditions
- Sarcopenia, Aging, Disability Physical
- Trial name
- DART (NCT03978572)
- Testing
- Resistance Training, Moderate-Intensity Continuous Cycling, High-Intensity Interval Cycling
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio University
Knee Osteoarthritis
The Efficacy of Exercise and Alternative Applications of NMES on Pain and Function in Patients With Knee OA
The aim of the study was to investigate the efficacy of exercise and different size electrodes of neuromuscular electrical stimulation (NMES) applications on pain, range of motion (ROM), muscle strength, function status and…
- Trial name
- NCT03571698
- Testing
- Neuromuscular Electrical Stimulator
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Multiple Sclerosis, Chronic Progressive, Multiple Sclerosis
MUSCLE - Nordic Walking in MUltiple SCLErosis
The aim of the study is to analyze the effects of Nordic Walking and free walking in the clinical-functional, postural balance, motor control, muscular echographic quality, and gait analysis (pendulum gait mechanism), in people…
- Conditions
- Multiple Sclerosis, Chronic Progressive, Multiple Sclerosis, Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary Progressive
- Trial name
- MUSCLE (NCT05385731)
- Testing
- Nordic Walking (NWG), Free Walking (FWG), Health Education (HEG)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Leonardo A. Peyré-Tartaruga
Pregnancy
Prenatal Exercise and Cardiovascular Health (PEACH)
Maintenance of a healthy pregnancy depends on an appropriate adaptation and responsiveness of blood vessels, to ensure appropriate blood flow to the fetus during everyday stressors.
- Trial name
- PEACH (NCT02948439)
- Testing
- Aerobic exercise
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Multiple Sclerosis
Relıabılıty and valıdıty of the supıne-to-stand Test wıth Multiple Sclerosis
Background: Supine-to-Stand Test (SST) requires muscle strength, flexibility, and dynamic balance and can be used as a marker of functional motor competence in patients with Multiple Sclerosis (pwMS).
- Trial name
- NCT06790992
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Sanko University
Chronic Obstructive Pulmonary Disease, Bronchiectasis
The Prevalence of Gastro-oesophageal Reflux in Chronic Lung Disease
Gastric reflux into the oesophagus may further lung damage in respiratory disease. The proportion of adults with chronic lung disease and gastric reflux is unknown.
- Trial name
- NCT00697177
- Where
- Australia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Stroke
Effects of Task-Based Mirror Therapy for Post-stroke Shoulder-Hand Syndrome
The study aims to determine the effects of task-based mirror therapy on edema, pain and upper limb motor function with shoulder-hand syndrome in post stroke patients.
- Trial name
- NCT07428811
- Testing
- Task based mirror therapy, Conventional exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Long COVID-19, Post-COVID-19 Syndrome
Exercise and Post-COVID/ Long-COVID: Effects of Different Training Modalities on Various Parameters in People Affected by the Sequelae of COVID-19
The current COVID-19 pandemic is the most severe health crisis of the 21st century. This is not only due to the deaths caused by the disease.
- Conditions
- Long COVID-19, Post-COVID-19 Syndrome, COVID-19
- Trial name
- NCT05204511
- Testing
- endurance training, concurrent training
- Where
- Austria
- Volunteers
- 66 people
- Sponsor
- University of Vienna
Stroke
Ipsihand Device Use in Stroke Patients to Assess Functional Motor Outcomes
This study aims to evaluate the impact of the Neurolutions Upper Extremity Rehabilitation System, known as IpsiHand, on improving functional motor control for post-stroke patients with hemiparesis.
- Trial name
- NCT04338971
- Testing
- IpsiHand Therapy
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Neurolutions, Inc.
Nutrition Disorder, Child, Gross Motor Development Delay
Effect of a Nutritional Support System for Improving Gross Motor Function in Cerebral Palsy
Background: Most patients with cerebral palsy (CP) are dependent on parents due to the spasticity and limitations in their gross motor function.
- Conditions
- Nutrition Disorder, Child, Gross Motor Development Delay, Neuro: Cerebral Palsy, Diet Modification
- Trial name
- ENSSIGMCP (NCT03933709)
- Testing
- Nutritional Support System (NSS), deworming, recommended diet
- Volunteers
- 30 people
- Sponsor
- Anahuac University
Surgery--Complications
Effect of Multimodal Postoperative Rehabilitation on Functional and Cognitive Decline
Older adults, especially those with frailty, have a higher risk for complications, functional and cognitive decline after urgent surgery.
- Trial name
- NCT05290532
- Testing
- Individualized exercise training
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Hospital of Navarra
Muscle Spasticity
Muscle Ultrasound Measures as Biomarkers of Upper Motor Neuron Function
Background: Primary lateral sclerosis (PLS) is a rare disease. It leads to weakness in the muscle of the arms, legs, and face. People with PLS develop muscle stiffness called spasticity.
- Trial name
- NCT02408900
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
DNS, Cerebral Palsy
Effects of Reflex Mediated Core Stability Exercise on Sensory Processing Skills and Gross Motor Function
Current literature on DNS in CP primarily focuses on motor outcomes like postural control and balance. Therefore, there are fewer studies up to researcher's knowledge about DNS's impact on broad sensory processing skills in CP.
- Conditions
- DNS, Cerebral Palsy, Sensory Processing Disorder, Gross Motor Function
- Trial name
- NCT07729800
- Testing
- Reflex mediated core stability exercise, conventional therapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Cognitive Impairment, Child Autism
Exercise and Cognition in Children With ASD
Physical exercise is widely reported to be beneficial to executive functions (EFs) in children with autism spectrum disorder (ASD).
- Trial name
- NCT05503459
- Testing
- Bicycle learning, Stationary cycling
- Where
- Hong Kong
- Volunteers
- 82 people
- Sponsor
- Education University of Hong Kong
Cerebrovascular Accident
Post-Stroke Improvement of Motor Function
Open-label clinical study where all new patients presenting with cerebrovascular accidents and consenting to treatment are given intravenously a new combination of medications.
- Trial name
- PSIOM (NCT03543917)
- Testing
- Perfusion with New Combination Medication
- Where
- Romania
- Volunteers
- 17 people
- Sponsor
- Fundatia Bio-Forum
Multiple Sclerosis
Effect of Multimodal Exercise Training in Patients With Multiple Sclerosis
The study aims to examine the effects of multimodal exercise training including aerobic, strengthening and balance exercises via face-to-face and asynchronous video-based telerehabilitation on disease activity, disability level…
- Trial name
- PwMS (NCT06676618)
- Testing
- Multimodal Exercise Training, Control Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University - Cerrahpasa
SCI - Spinal Cord Injury, Motor Imagery
Near-Infrared Imaging of Motor Imagery Effects in Spinal Cord Injury
The primary objective of this clinical trial is to investigate the efficacy of motor imagery-based brain-computer interface (MI-BCI) technology in improving motor function among patients with spinal cord injury (SCI), as well as…
- Conditions
- SCI - Spinal Cord Injury, Motor Imagery, Brain-Computer Interfaces
- Trial name
- NCT07106060
- Testing
- EEG-based rehabilitation training device (L-B300), EEG-based rehabilitation training device (L-B300)（Not connected）
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shengjing Hospital
Multiple Sclerosis, Hypertension
Vascular Mechanisms, Functional Outcomes, & Exercise Among Persons With Multiple Sclerosis With Hypertension
The goal of this study is to determine if 12 weeks of cycling exercise training at home will improve three parameters: 1) blood pressure, 2) cognition, and 3) walking ability among persons with multiple sclerosis who have high…
- Trial name
- NCT06554340
- Testing
- Home-based aerobic training
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Massachusetts, Boston